ECSP045245A - N-aril-2-oxazolidinona-5-carboxamidas y sus derivados - Google Patents

N-aril-2-oxazolidinona-5-carboxamidas y sus derivados

Info

Publication number
ECSP045245A
ECSP045245A EC2004005245A ECSP045245A ECSP045245A EC SP045245 A ECSP045245 A EC SP045245A EC 2004005245 A EC2004005245 A EC 2004005245A EC SP045245 A ECSP045245 A EC SP045245A EC SP045245 A ECSP045245 A EC SP045245A
Authority
EC
Ecuador
Prior art keywords
oxazolidinona
carboxamids
aril
derivatives
formulas
Prior art date
Application number
EC2004005245A
Other languages
English (en)
Inventor
Richard C Thomas
Toni-Jo Poel
Michael Robert Barbachyn
Mikhail F Gordeev
Gary W Luehr
Adam Renslo
Upinder Singh
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of ECSP045245A publication Critical patent/ECSP045245A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención proporciona agentes antibacterianos que tienen las fórmulas I, II y III descritas en la presente memoria descriptiva.
EC2004005245A 2002-02-25 2004-08-25 N-aril-2-oxazolidinona-5-carboxamidas y sus derivados ECSP045245A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35949502P 2002-02-25 2002-02-25

Publications (1)

Publication Number Publication Date
ECSP045245A true ECSP045245A (es) 2004-09-28

Family

ID=27766097

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2004005245A ECSP045245A (es) 2002-02-25 2004-08-25 N-aril-2-oxazolidinona-5-carboxamidas y sus derivados

Country Status (36)

Country Link
US (1) US6919329B2 (es)
EP (1) EP1478629B1 (es)
JP (1) JP2005524660A (es)
KR (1) KR100613532B1 (es)
CN (1) CN1639135A (es)
AP (1) AP1902A (es)
AR (1) AR038536A1 (es)
AT (1) ATE342258T1 (es)
AU (1) AU2003210807A1 (es)
BR (1) BR0307924A (es)
CA (1) CA2476038A1 (es)
CO (1) CO5611128A2 (es)
CY (1) CY1105797T1 (es)
DE (1) DE60308998T2 (es)
DK (1) DK1478629T3 (es)
EA (1) EA007490B1 (es)
EC (1) ECSP045245A (es)
ES (1) ES2271615T3 (es)
GE (1) GEP20074198B (es)
HR (1) HRP20040717A2 (es)
IS (1) IS7376A (es)
MA (1) MA27180A1 (es)
MX (1) MXPA04008205A (es)
MY (1) MY135233A (es)
NO (1) NO20044062L (es)
NZ (1) NZ534521A (es)
OA (1) OA12779A (es)
PL (1) PL372461A1 (es)
PT (1) PT1478629E (es)
SI (1) SI1478629T1 (es)
TN (1) TNSN04163A1 (es)
TW (1) TW200305568A (es)
UA (1) UA80112C2 (es)
WO (1) WO2003072553A1 (es)
YU (1) YU72804A (es)
ZA (1) ZA200406362B (es)

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EP1451164A2 (en) * 2001-07-12 2004-09-01 PHARMACIA & UPJOHN COMPANY Amide derivatives having improved solubility

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ATE342258T1 (de) 2006-11-15
NO20044062L (no) 2004-10-26
DK1478629T3 (da) 2007-01-29
ZA200406362B (en) 2006-02-22
KR20040091668A (ko) 2004-10-28
WO2003072553A8 (en) 2004-09-16
MA27180A1 (fr) 2005-01-03
IS7376A (is) 2004-07-29
UA80112C2 (en) 2007-08-27
BR0307924A (pt) 2004-12-07
MY135233A (en) 2008-03-31
US6919329B2 (en) 2005-07-19
OA12779A (en) 2006-07-06
DE60308998D1 (de) 2006-11-23
JP2005524660A (ja) 2005-08-18
PL372461A1 (en) 2005-07-25
YU72804A (sh) 2006-08-17
EP1478629A1 (en) 2004-11-24
AU2003210807A1 (en) 2003-09-09
CN1639135A (zh) 2005-07-13
GEP20074198B (en) 2007-09-25
US20040044052A1 (en) 2004-03-04
MXPA04008205A (es) 2004-11-26
EA200400893A1 (ru) 2005-02-24
CO5611128A2 (es) 2006-02-28
CA2476038A1 (en) 2003-09-04
AP1902A (en) 2008-10-15
SI1478629T1 (sl) 2007-02-28
EP1478629B1 (en) 2006-10-11
KR100613532B1 (ko) 2006-08-16
EA007490B1 (ru) 2006-10-27
ES2271615T3 (es) 2007-04-16
AR038536A1 (es) 2005-01-19
WO2003072553A1 (en) 2003-09-04
CY1105797T1 (el) 2011-02-02
PT1478629E (pt) 2007-01-31
AP2004003110A0 (en) 2004-09-30
TNSN04163A1 (fr) 2007-03-12
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NZ534521A (en) 2007-02-23
HRP20040717A2 (en) 2005-02-28

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