MA27180A1 - N-aryl-2-oxazolidinone-5-carboxamides et leurs derives, et leur utilisation comme agents antibacteriens - Google Patents

N-aryl-2-oxazolidinone-5-carboxamides et leurs derives, et leur utilisation comme agents antibacteriens

Info

Publication number
MA27180A1
MA27180A1 MA27837A MA27837A MA27180A1 MA 27180 A1 MA27180 A1 MA 27180A1 MA 27837 A MA27837 A MA 27837A MA 27837 A MA27837 A MA 27837A MA 27180 A1 MA27180 A1 MA 27180A1
Authority
MA
Morocco
Prior art keywords
aryl
antibacterial agents
oxazolidinone
carboxamides
derivatives
Prior art date
Application number
MA27837A
Other languages
English (en)
Inventor
Richard C Thomas
Michael R Barbachyn
Gary W Luehr
Upinder Singh
Toni-Jo Poel
Mikhail F Gordeev
Adam Renslo
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of MA27180A1 publication Critical patent/MA27180A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom

Abstract

DEPOSANT Société dite: PHARMACIA & UPJOHN COMPANY REVENDICATION DE PRIORITES US 25 Février 2002 60/359,495 Voir en annexe le titre de l'invention et le texte de l'abrégé N-aryl-2-oxazolidinone-5-carboxamides et leurs dérivés, et leur utilisation comme agents antibactériens Les composés de formule B-C-A-CO-NH-R1 dans laquelle A a la structure i, ii ou iii, de formule (I), (II) ou (III), C représente un groupe aryle ou hétéroaryle facultativement substitué et B représente un groupement cyclique spécifié, ou bien C et B, conjointement, représentent un groupement hétérobicyclique, sont utiles comme agents antibactériens.
MA27837A 2002-02-25 2004-08-24 N-aryl-2-oxazolidinone-5-carboxamides et leurs derives, et leur utilisation comme agents antibacteriens MA27180A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35949502P 2002-02-25 2002-02-25

Publications (1)

Publication Number Publication Date
MA27180A1 true MA27180A1 (fr) 2005-01-03

Family

ID=27766097

Family Applications (1)

Application Number Title Priority Date Filing Date
MA27837A MA27180A1 (fr) 2002-02-25 2004-08-24 N-aryl-2-oxazolidinone-5-carboxamides et leurs derives, et leur utilisation comme agents antibacteriens

Country Status (36)

Country Link
US (1) US6919329B2 (fr)
EP (1) EP1478629B1 (fr)
JP (1) JP2005524660A (fr)
KR (1) KR100613532B1 (fr)
CN (1) CN1639135A (fr)
AP (1) AP1902A (fr)
AR (1) AR038536A1 (fr)
AT (1) ATE342258T1 (fr)
AU (1) AU2003210807A1 (fr)
BR (1) BR0307924A (fr)
CA (1) CA2476038A1 (fr)
CO (1) CO5611128A2 (fr)
CY (1) CY1105797T1 (fr)
DE (1) DE60308998T2 (fr)
DK (1) DK1478629T3 (fr)
EA (1) EA007490B1 (fr)
EC (1) ECSP045245A (fr)
ES (1) ES2271615T3 (fr)
GE (1) GEP20074198B (fr)
HR (1) HRP20040717A2 (fr)
IS (1) IS7376A (fr)
MA (1) MA27180A1 (fr)
MX (1) MXPA04008205A (fr)
MY (1) MY135233A (fr)
NO (1) NO20044062L (fr)
NZ (1) NZ534521A (fr)
OA (1) OA12779A (fr)
PL (1) PL372461A1 (fr)
PT (1) PT1478629E (fr)
SI (1) SI1478629T1 (fr)
TN (1) TNSN04163A1 (fr)
TW (1) TW200305568A (fr)
UA (1) UA80112C2 (fr)
WO (1) WO2003072553A1 (fr)
YU (1) YU72804A (fr)
ZA (1) ZA200406362B (fr)

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Also Published As

Publication number Publication date
AP2004003110A0 (en) 2004-09-30
AP1902A (en) 2008-10-15
EA007490B1 (ru) 2006-10-27
MY135233A (en) 2008-03-31
WO2003072553A8 (fr) 2004-09-16
WO2003072553A1 (fr) 2003-09-04
BR0307924A (pt) 2004-12-07
ES2271615T3 (es) 2007-04-16
PL372461A1 (en) 2005-07-25
PT1478629E (pt) 2007-01-31
ZA200406362B (en) 2006-02-22
MXPA04008205A (es) 2004-11-26
SI1478629T1 (sl) 2007-02-28
UA80112C2 (en) 2007-08-27
TNSN04163A1 (fr) 2007-03-12
EA200400893A1 (ru) 2005-02-24
IS7376A (is) 2004-07-29
NZ534521A (en) 2007-02-23
KR20040091668A (ko) 2004-10-28
YU72804A (sh) 2006-08-17
EP1478629A1 (fr) 2004-11-24
ATE342258T1 (de) 2006-11-15
CO5611128A2 (es) 2006-02-28
CN1639135A (zh) 2005-07-13
GEP20074198B (en) 2007-09-25
NO20044062L (no) 2004-10-26
AU2003210807A1 (en) 2003-09-09
KR100613532B1 (ko) 2006-08-16
US20040044052A1 (en) 2004-03-04
EP1478629B1 (fr) 2006-10-11
US6919329B2 (en) 2005-07-19
TW200305568A (en) 2003-11-01
CY1105797T1 (el) 2011-02-02
JP2005524660A (ja) 2005-08-18
DE60308998D1 (de) 2006-11-23
CA2476038A1 (fr) 2003-09-04
AR038536A1 (es) 2005-01-19
DE60308998T2 (de) 2007-03-01
HRP20040717A2 (en) 2005-02-28
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ECSP045245A (es) 2004-09-28
OA12779A (en) 2006-07-06

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