BRPI0409217A - derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona - Google Patents

derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Info

Publication number
BRPI0409217A
BRPI0409217A BRPI0409217-1A BRPI0409217A BRPI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A BR PI0409217 A BRPI0409217 A BR PI0409217A
Authority
BR
Brazil
Prior art keywords
derivatives
bicycloexylphenyloxazolidinone
analogues
methods
antimicrobial derivatives
Prior art date
Application number
BRPI0409217-1A
Other languages
English (en)
Inventor
Adam Robert Renslo
Mikhail Fedor Gordeev
Dinesh Vinoobhai Patel
Hongwu Gao
Vara Prassad Venkata N Josyula
Original Assignee
Pharmacia & Upjohn Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Co Llc filed Critical Pharmacia & Upjohn Co Llc
Publication of BRPI0409217A publication Critical patent/BRPI0409217A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings

Abstract

"DERIVADOS E ANáLOGOS ANTIMICROBIANOS DA ¢3.1.0! BICICLOEXILFENILOXAZOLIDINONA". A presente invenção proporciona alguns derivados ¢3.1.0! bicíclicos de oxazolidinona de Fórmula I ou seus sais ou promedicamentos farmaceuticamente aceitáveis que são agentes antibacterianos, composições farmacêuticas que os contêm, métodos para a sua utilização e métodos para preparar estes compostos.
BRPI0409217-1A 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona BRPI0409217A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US46113403P 2003-04-09 2003-04-09
PCT/IB2004/001135 WO2004089943A1 (en) 2003-04-09 2004-03-30 Antimicrobial [3.1.0] bicyclohexylphenyl-oxazolidinone derivatives and analogues

Publications (1)

Publication Number Publication Date
BRPI0409217A true BRPI0409217A (pt) 2006-03-28

Family

ID=33159819

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409217-1A BRPI0409217A (pt) 2003-04-09 2004-03-30 derivados e análogos antimicrobianos da [3.1.0]bicicloexilfeniloxazolidinona

Country Status (7)

Country Link
US (2) US7279494B2 (pt)
EP (1) EP1615916A1 (pt)
JP (1) JP2006522791A (pt)
BR (1) BRPI0409217A (pt)
CA (1) CA2521685A1 (pt)
MX (1) MXPA05010783A (pt)
WO (1) WO2004089943A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2492264A3 (en) 2003-06-03 2012-12-19 Rib-X Pharmaceuticals, Inc. Biaryl Heterocyclic Compounds And Methods Of Making And Using The Same
US8324398B2 (en) 2003-06-03 2012-12-04 Rib-X Pharmaceuticals, Inc. Process for the synthesis of biaryl oxazolidinones
CA2529292A1 (en) * 2003-07-02 2005-01-20 Merck & Co., Inc. Oxazolidinone antibiotics and derivatives thereof
CA2530140C (en) * 2003-07-02 2010-11-09 Merck & Co., Inc. Cyclopropyl group substituted oxazolidinone antibiotics and derivatives thereof
EP1713785A1 (en) 2003-12-17 2006-10-25 Rib-X Pharmaceuticals, Inc. Halogenated biaryl heterocyclic compounds and methods of making and using the same
WO2006133397A2 (en) 2005-06-08 2006-12-14 Rib-X Pharmaceuticals, Inc. Process for the synthesis of triazoles
CA2743971A1 (en) 2008-11-20 2010-05-27 Panacea Biotec Ltd. Novel antimicrobials
BR112012000657A2 (pt) 2009-06-26 2016-11-16 Panacea Biotec Ltd novos azabicilohexanos
BR112013007566A2 (pt) 2010-09-28 2016-08-02 Panacea Biotec Ltd novos compostos bicíclicos
WO2012059823A1 (en) * 2010-11-03 2012-05-10 Wockhardt Limited Process for the preparation of phosphoric acid mono- (l-{4- [(s) -5- (acetylaminomethyl) - 2 - oxo - oxazolidin- 3 - yl] - 2, 6 - difluorophenyl} - 4 -methoxymethylpiperidin- 4 - yl) ester

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) * 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) * 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) * 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
MY115155A (en) 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
GB9702213D0 (en) 1996-02-24 1997-03-26 Zeneca Ltd Chemical compounds
EP0984947B8 (en) 1997-05-30 2005-06-15 Pharmacia & Upjohn Company LLC Oxazolidinone antibacterial agents having a thiocarbonyl functionality
AU764184B2 (en) * 1998-01-23 2003-08-14 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
CN1311787A (zh) 1998-06-05 2001-09-05 阿斯特拉曾尼卡有限公司 噁唑烷酮衍生物、其制备方法以及含有它们的药物组合物
GB9821938D0 (en) 1998-10-09 1998-12-02 Zeneca Ltd Chemical compounds
TWI244481B (en) * 1998-12-23 2005-12-01 Pfizer 3-azabicyclo[3.1.0]hexane derivatives useful in therapy
HUP0203869A2 (hu) * 1999-12-21 2003-07-28 Pharmacia & Upjohn Co. Szulfoximin funkcionalitással rendelkező oxazolidinok és alkalmazásuk mikrobaellenes szerként, a vegyületeket tartalmazó gyógyszerkészítmények
GB0009803D0 (en) 2000-04-25 2000-06-07 Astrazeneca Ab Chemical compounds
PL363960A1 (en) 2000-07-17 2004-11-29 Ranbaxy Laboratories Limited Oxazolidinone derivatives as antimicrobials
ATE321024T1 (de) * 2000-10-17 2006-04-15 Pharmacia & Upjohn Co Llc Verfahren zur herstellung von oxazolidinonverbindungen
AR038536A1 (es) * 2002-02-25 2005-01-19 Upjohn Co N-aril-2-oxazolidinona-5- carboxamidas y sus derivados

Also Published As

Publication number Publication date
US20080090884A1 (en) 2008-04-17
CA2521685A1 (en) 2004-10-21
WO2004089943A1 (en) 2004-10-21
JP2006522791A (ja) 2006-10-05
WO2004089943A8 (en) 2005-09-29
EP1615916A1 (en) 2006-01-18
MXPA05010783A (es) 2005-12-12
US7279494B2 (en) 2007-10-09
US20050192325A1 (en) 2005-09-01

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2159 DE 22/05/2012.