BR112013007566A2 - novos compostos bicíclicos - Google Patents

novos compostos bicíclicos

Info

Publication number
BR112013007566A2
BR112013007566A2 BR112013007566A BR112013007566A BR112013007566A2 BR 112013007566 A2 BR112013007566 A2 BR 112013007566A2 BR 112013007566 A BR112013007566 A BR 112013007566A BR 112013007566 A BR112013007566 A BR 112013007566A BR 112013007566 A2 BR112013007566 A2 BR 112013007566A2
Authority
BR
Brazil
Prior art keywords
formula
compounds
gpcr
polymorphs
prodrugs
Prior art date
Application number
BR112013007566A
Other languages
English (en)
Inventor
Jagattaran Das
Nishan Singh
Rajesh Jain
Sanjay Trehan
Sudhir Kumar Sharma
Original Assignee
Panacea Biotec Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd
Publication of BR112013007566A2 publication Critical patent/BR112013007566A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

novos compostos bicíclicos. a presente invenção refere-se a novos compostos de fórmula i, os seus derivados farmaceuticamente aceitáveis, formas tautoméricas, os seus isômeros, polimorfos, pró-drogas, metabolitos, sais ou solvatos. a invenção também se refere a processos para a síntese de novos compostos de fórmula i, os seus derivados farmaceuticamente aceitáveis, formas tautoméricas, os seus isômeros, polimorfos, pró-drogas, metabolitos, sais ou solvatos. a presente invenção proporciona ainda composições farmacêuticas compreendendo os compostos de fórmula i e aos métodos de tratamento ou prevenção de uma ou mais desordens do sistema nervoso central e/ou periférico, de preferência por modulação dos alvos neurológicos e/ou psiquiátricos (gpcr e/ou não-gpcr).
BR112013007566A 2010-09-28 2011-09-27 novos compostos bicíclicos BR112013007566A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN2322DE2010 2010-09-28
IN1515DE2011 2011-05-26
PCT/IN2011/000669 WO2012042539A2 (en) 2010-09-28 2011-09-27 Novel bicyclic compounds

Publications (1)

Publication Number Publication Date
BR112013007566A2 true BR112013007566A2 (pt) 2016-08-02

Family

ID=45048157

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013007566A BR112013007566A2 (pt) 2010-09-28 2011-09-27 novos compostos bicíclicos

Country Status (6)

Country Link
US (1) US9133116B2 (pt)
EP (1) EP2621902B1 (pt)
JP (1) JP2013542929A (pt)
AR (1) AR083202A1 (pt)
BR (1) BR112013007566A2 (pt)
WO (1) WO2012042539A2 (pt)

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Also Published As

Publication number Publication date
US9133116B2 (en) 2015-09-15
AR083202A1 (es) 2013-02-06
EP2621902B1 (en) 2017-04-12
JP2013542929A (ja) 2013-11-28
WO2012042539A3 (en) 2012-05-31
US20130253029A1 (en) 2013-09-26
WO2012042539A2 (en) 2012-04-05
EP2621902A2 (en) 2013-08-07

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