MA27860A1 - Derives de lincomycine nouveaux possedant une activite antimicrobienne - Google Patents
Derives de lincomycine nouveaux possedant une activite antimicrobienneInfo
- Publication number
- MA27860A1 MA27860A1 MA28672A MA28672A MA27860A1 MA 27860 A1 MA27860 A1 MA 27860A1 MA 28672 A MA28672 A MA 28672A MA 28672 A MA28672 A MA 28672A MA 27860 A1 MA27860 A1 MA 27860A1
- Authority
- MA
- Morocco
- Prior art keywords
- new
- lincomycin derivatives
- antimicrobial activity
- lincomycin
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
- C07H15/16—Lincomycin; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Crystallography & Structural Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
Dérivés de lincomycine nouveaux possédant une activité antimicrobienne Des dérivés de lincomycine nouveaux sont décrits. Ces dérivés de lincomycine présentent une activité antibactérienne. Les composés de la présente invention peuvent présenter de puissantes activités contre des bactéries, comprenant des organismes Gram-positifs, et peuvent être des agents antimicrobiens utiles. Des procédés de synthèse et méthodes d'utilisation des composés sont également décrits.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47929603P | 2003-06-17 | 2003-06-17 | |
US47950203P | 2003-06-17 | 2003-06-17 | |
US10/642,807 US7164011B2 (en) | 2002-08-15 | 2003-08-15 | Lincomycin derivatives possessing antibacterial activity |
US10/777,455 US7199105B2 (en) | 2002-08-15 | 2004-02-11 | Lincomycin derivatives possessing antibacterial activity |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27860A1 true MA27860A1 (fr) | 2006-04-03 |
Family
ID=40203032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA28672A MA27860A1 (fr) | 2003-06-17 | 2005-12-16 | Derives de lincomycine nouveaux possedant une activite antimicrobienne |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP1644393A2 (fr) |
JP (1) | JP2007516172A (fr) |
KR (1) | KR20060091050A (fr) |
AU (1) | AU2004261550A1 (fr) |
BR (1) | BRPI0411534A (fr) |
CA (1) | CA2528592A1 (fr) |
EC (1) | ECSP056233A (fr) |
GE (1) | GEP20084437B (fr) |
HK (1) | HK1090061A1 (fr) |
IL (1) | IL172183A0 (fr) |
IS (1) | IS8147A (fr) |
MA (1) | MA27860A1 (fr) |
MX (1) | MXPA05013915A (fr) |
NO (1) | NO20055893L (fr) |
OA (1) | OA13179A (fr) |
RS (1) | RS20050931A (fr) |
WO (1) | WO2005012320A2 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7199105B2 (en) | 2002-08-15 | 2007-04-03 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antibacterial activity |
CA2493799A1 (fr) | 2002-08-15 | 2004-02-26 | Vicuron Pharmaceuticals, Inc. | Derives de lincomycine presentant une activite antibacterienne |
US7256177B2 (en) | 2003-06-17 | 2007-08-14 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antibacterial activity |
US7199106B2 (en) | 2003-06-17 | 2007-04-03 | Vicuron Pharmaceuticals, Inc. | Lincomycin derivatives possessing antimicrobial activity |
EP1654268A2 (fr) * | 2003-06-17 | 2006-05-10 | Vicuron Pharmaceuticals, Inc. | Derives de lincomycine a activite anti-bacterienne |
US7361743B2 (en) | 2004-02-11 | 2008-04-22 | Pfizer Inc | Lincomycin derivatives possessing antibacterial activity |
CN101291916A (zh) * | 2005-08-31 | 2008-10-22 | 惠氏公司 | 甘氨酰环素的9-氨基羰基取代衍生物 |
US7871982B2 (en) | 2005-12-09 | 2011-01-18 | Meiji Seika Kaisha, Ltd. | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient |
EP2166015A4 (fr) | 2007-05-31 | 2012-09-05 | Meiji Seika Kaisha | Dérivé de la lincosamide et agent antibactérien le comprenant en tant qu'ingrédient actif |
EP2151447A4 (fr) * | 2007-05-31 | 2012-09-05 | Meiji Seika Kaisha | Dérivés de la lincomycine et agents antibactériens les contenant en tant qu'ingrédient actif |
US20130267699A1 (en) | 2011-06-24 | 2013-10-10 | California Institute Of Technology | Quaternary heteroatom containing compounds |
US8822679B2 (en) * | 2011-06-24 | 2014-09-02 | California Institute Of Technology | Quaternary heteroatom containing compounds |
US10421696B2 (en) | 2014-12-18 | 2019-09-24 | California Institute Of Technology | Enantioselective synthesis of α-quaternary mannich adducts by palladium-catalyzed allylic alkylation |
EP3274342B1 (fr) | 2015-03-27 | 2022-05-04 | California Institute of Technology | Alkylation décarboxylative catalytique asymétrique d'alkyle au moyen de faibles concentrations de catalyseur et d'un précatalyseur robuste |
WO2017156239A1 (fr) | 2016-03-11 | 2017-09-14 | California Institute Of Technology | Compositions et procédés d'acylation de lactames |
EP3480190B1 (fr) | 2017-11-01 | 2023-01-04 | California Institute of Technology | Procédés d'alkylation allylique énantiosélective d'esters, lactones et lactames avec des alcools allyliques inactivés |
US11214568B2 (en) | 2018-10-18 | 2022-01-04 | California Institute Of Technology | Gem-disubstituted pyrrolidines, piperazines, and diazepanes, and compositions and methods of making the same |
CN110357839A (zh) * | 2019-08-29 | 2019-10-22 | 重庆经致制药技术开发有限公司 | 布瓦西坦手性中间体的制备方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL128232C (fr) * | 1964-04-13 | |||
US3268556A (en) * | 1964-04-13 | 1966-08-23 | Upjohn Co | Novel lincomycin derivatives |
NL146501C (fr) * | 1964-07-01 | |||
US3282917A (en) * | 1964-08-17 | 1966-11-01 | Upjohn Co | Methyl n-(1-alkyl-4-alkoxy-prolyl)-alpha-thiolincosaminide compounds and process therefor |
NL140527B (nl) * | 1965-02-08 | 1973-12-17 | Upjohn Co | Werkwijze ter bereiding van aan lincomycine verwante verbindingen. |
US3496163A (en) * | 1965-02-08 | 1970-02-17 | Upjohn Co | 7-halo-7-deoxylincomycins and process for preparing the same |
US3555007A (en) * | 1968-07-22 | 1971-01-12 | Upjohn Co | 7-deoxy-7-halo lincomycin d derivatives |
US3549615A (en) * | 1968-10-17 | 1970-12-22 | Upjohn Co | Lincomycin derivatives and process for producing the same |
DE2118636A1 (de) * | 1970-04-20 | 1971-11-04 | The Upjohn Co., Kalamazoo, Mich. (V.StA.) | 3-Nucleotide von Lincomycin und deren Analogen, Verfahren zu ihrer Herstellung und ihre Verwendung in therapeutischen Präparaten |
US3787390A (en) * | 1971-06-23 | 1974-01-22 | Upjohn Co | Analogs of lincomycin and process |
US3849396A (en) * | 1973-01-08 | 1974-11-19 | Upjohn Co | Lincomycin and clindamycin 1-o-ethers |
US3923602A (en) * | 1973-10-25 | 1975-12-02 | Upjohn Co | Composition of matter and process |
JPS5641239A (en) * | 1979-09-13 | 1981-04-17 | Hitachi Cable Ltd | Flame-retardant composition |
US4278789A (en) * | 1979-11-23 | 1981-07-14 | The Upjohn Company | Lincomycin compounds |
CA2493799A1 (fr) * | 2002-08-15 | 2004-02-26 | Vicuron Pharmaceuticals, Inc. | Derives de lincomycine presentant une activite antibacterienne |
BRPI0411537A (pt) * | 2003-06-17 | 2006-08-01 | Vicuron Pharm Inc | derivados de lincomicina que possuem atividade antibacteriana |
-
2004
- 2004-06-17 WO PCT/US2004/019689 patent/WO2005012320A2/fr active Application Filing
- 2004-06-17 AU AU2004261550A patent/AU2004261550A1/en not_active Abandoned
- 2004-06-17 KR KR1020057024291A patent/KR20060091050A/ko active Search and Examination
- 2004-06-17 BR BRPI0411534-1A patent/BRPI0411534A/pt not_active IP Right Cessation
- 2004-06-17 EP EP04776816A patent/EP1644393A2/fr not_active Withdrawn
- 2004-06-17 RS YUP-2005/0931A patent/RS20050931A/sr unknown
- 2004-06-17 OA OA1200500364A patent/OA13179A/en unknown
- 2004-06-17 MX MXPA05013915A patent/MXPA05013915A/es unknown
- 2004-06-17 CA CA002528592A patent/CA2528592A1/fr not_active Abandoned
- 2004-06-17 GE GEAP20049117A patent/GEP20084437B/en unknown
- 2004-06-17 JP JP2006517464A patent/JP2007516172A/ja active Pending
-
2005
- 2005-11-24 IS IS8147A patent/IS8147A/is unknown
- 2005-11-24 IL IL172183A patent/IL172183A0/en unknown
- 2005-12-12 NO NO20055893A patent/NO20055893L/no not_active Application Discontinuation
- 2005-12-16 MA MA28672A patent/MA27860A1/fr unknown
- 2005-12-16 EC EC2005006233A patent/ECSP056233A/es unknown
-
2006
- 2006-09-21 HK HK06110528.4A patent/HK1090061A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2004261550A1 (en) | 2005-02-10 |
GEP20084437B (en) | 2008-07-25 |
WO2005012320A2 (fr) | 2005-02-10 |
HK1090061A1 (en) | 2006-12-15 |
WO2005012320A3 (fr) | 2005-10-20 |
CA2528592A1 (fr) | 2005-02-10 |
NO20055893L (no) | 2006-03-14 |
IS8147A (is) | 2005-11-24 |
RS20050931A (en) | 2008-04-04 |
OA13179A (en) | 2006-12-13 |
KR20060091050A (ko) | 2006-08-17 |
BRPI0411534A (pt) | 2006-08-22 |
EP1644393A2 (fr) | 2006-04-12 |
ECSP056233A (es) | 2006-04-19 |
MXPA05013915A (es) | 2006-07-03 |
IL172183A0 (en) | 2011-08-01 |
JP2007516172A (ja) | 2007-06-21 |
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