EA202090994A1 - Композиции и способы ингибирования экспрессии генов вируса гепатита в - Google Patents

Композиции и способы ингибирования экспрессии генов вируса гепатита в

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EA202090994A1
EA202090994A1 EA202090994A EA202090994A EA202090994A1 EA 202090994 A1 EA202090994 A1 EA 202090994A1 EA 202090994 A EA202090994 A EA 202090994A EA 202090994 A EA202090994 A EA 202090994A EA 202090994 A1 EA202090994 A1 EA 202090994A1
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Prior art keywords
hepatitis
inhibiting
expression
methods
compositions
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EA202090994A
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English (en)
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Дэниел Чин
Йохен Деккерт
Маркус Хоссбах
Маттиас Йон
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Эрроухэд Фармасьютикалс, Инк.
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Publication of EA202090994A1 publication Critical patent/EA202090994A1/ru

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Abstract

Настоящее изобретение относится к двунитевой рибонуклеиновой кислоте (днРНК) для ингибирования экспрессии гена вируса гепатита B. Изобретение также относится к фармацевтической композиции, которая содержит днРНК, или молекулы нуклеиновой кислоты, или векторы, кодирующие их, вместе с фармацевтически приемлемым носителем; к способам для лечения заболеваний, вызванных инфекцией вируса гепатита B, с применением указанной фармацевтической композиции, и способам ингибирования экспрессии гена вируса геатита B в клетке.
EA202090994A 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в EA202090994A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11172235 2011-06-30
US13/535,454 US8809293B2 (en) 2011-06-30 2012-06-28 Compositions and methods for inhibiting gene expression of hepatitis B virus

Publications (1)

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EA202090994A1 true EA202090994A1 (ru) 2020-08-31

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Application Number Title Priority Date Filing Date
EA202090994A EA202090994A1 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в
EA201690497A EA035756B1 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в
EA202191537A EA202191537A1 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в
EA201391394A EA024762B9 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в

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EA201690497A EA035756B1 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в
EA202191537A EA202191537A1 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в
EA201391394A EA024762B9 (ru) 2011-06-30 2012-06-28 Композиции и способы ингибирования экспрессии генов вируса гепатита в

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US (2) US8809293B2 (ru)
EP (3) EP3418386B1 (ru)
JP (5) JP6165723B2 (ru)
KR (5) KR102434357B1 (ru)
CN (3) CN106434665B (ru)
AU (5) AU2012275355B2 (ru)
BR (1) BR112013031021A2 (ru)
CA (2) CA2833778C (ru)
DK (1) DK2726613T3 (ru)
EA (4) EA202090994A1 (ru)
ES (1) ES2690538T3 (ru)
HK (1) HK1193633A1 (ru)
HR (1) HRP20181564T1 (ru)
IL (3) IL230226B (ru)
MX (2) MX342731B (ru)
PL (1) PL2726613T3 (ru)
PT (1) PT2726613T (ru)
SG (1) SG194751A1 (ru)
SI (1) SI2726613T1 (ru)
TW (4) TWI695066B (ru)
WO (1) WO2013003520A1 (ru)
ZA (1) ZA201307914B (ru)

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