MX2011007776A - Compsiciones y metodos para inhibir la expresion de genes ptp1b. - Google Patents
Compsiciones y metodos para inhibir la expresion de genes ptp1b.Info
- Publication number
- MX2011007776A MX2011007776A MX2011007776A MX2011007776A MX2011007776A MX 2011007776 A MX2011007776 A MX 2011007776A MX 2011007776 A MX2011007776 A MX 2011007776A MX 2011007776 A MX2011007776 A MX 2011007776A MX 2011007776 A MX2011007776 A MX 2011007776A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- expression
- compositions
- inhibiting expression
- ptplb
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/03—Phosphoric monoester hydrolases (3.1.3)
- C12Y301/03048—Protein-tyrosine-phosphatase (3.1.3.48)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
Abstract
Esta invención se refiere a un ácido ribonucleico bicatenario (ARNds) para inhibir la expresión de un gen PTP1B. La invención también se refiere a una composición farmacéutica que comprende las moléculas o vectores de ARNds o de ácido nucleico que codifican éstos junto con un portador farmacéuticamente aceptable; métodos para tratar enfermedades causadas por la expresión de un gen PTP1B utilizando tal composición farmacéutica; y métodos para inhibir la expresión de PTP1B en una célula.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09151962 | 2009-02-03 | ||
PCT/EP2010/050814 WO2010089221A1 (en) | 2009-02-03 | 2010-01-26 | Compositions and methods for inhibiting expression of ptp1b genes |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011007776A true MX2011007776A (es) | 2011-08-12 |
Family
ID=41786274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011007776A MX2011007776A (es) | 2009-02-03 | 2010-01-26 | Compsiciones y metodos para inhibir la expresion de genes ptp1b. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20100197773A1 (es) |
EP (1) | EP2393926A1 (es) |
KR (1) | KR20110100316A (es) |
CN (1) | CN102307996A (es) |
AR (1) | AR075688A1 (es) |
AU (1) | AU2010211133A1 (es) |
BR (1) | BRPI1008109A2 (es) |
CA (1) | CA2750459A1 (es) |
IL (1) | IL213147A0 (es) |
MX (1) | MX2011007776A (es) |
SG (1) | SG173182A1 (es) |
TW (1) | TW201031425A (es) |
WO (1) | WO2010089221A1 (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2012242642A1 (en) | 2011-04-13 | 2013-05-02 | Ionis Pharmaceuticals, Inc. | Antisense modulation of PTP1B expression |
KR102100093B1 (ko) | 2012-07-31 | 2020-05-15 | 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 | 췌장 베타 세포 형성의 생체내 유도를 위한 방법 및 조성물 |
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-
2010
- 2010-01-26 CA CA2750459A patent/CA2750459A1/en not_active Abandoned
- 2010-01-26 KR KR1020117017998A patent/KR20110100316A/ko not_active Application Discontinuation
- 2010-01-26 EP EP10701514A patent/EP2393926A1/en not_active Withdrawn
- 2010-01-26 BR BRPI1008109-7A patent/BRPI1008109A2/pt not_active IP Right Cessation
- 2010-01-26 WO PCT/EP2010/050814 patent/WO2010089221A1/en active Application Filing
- 2010-01-26 CN CN2010800064446A patent/CN102307996A/zh active Pending
- 2010-01-26 AU AU2010211133A patent/AU2010211133A1/en not_active Abandoned
- 2010-01-26 SG SG2011054731A patent/SG173182A1/en unknown
- 2010-01-26 MX MX2011007776A patent/MX2011007776A/es not_active Application Discontinuation
- 2010-01-29 US US12/696,100 patent/US20100197773A1/en not_active Abandoned
- 2010-02-02 AR ARP100100271A patent/AR075688A1/es unknown
- 2010-02-02 TW TW099103073A patent/TW201031425A/zh unknown
-
2011
- 2011-05-26 IL IL213147A patent/IL213147A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
BRPI1008109A2 (pt) | 2015-08-25 |
TW201031425A (en) | 2010-09-01 |
AU2010211133A1 (en) | 2011-07-21 |
KR20110100316A (ko) | 2011-09-09 |
AR075688A1 (es) | 2011-04-20 |
US20100197773A1 (en) | 2010-08-05 |
EP2393926A1 (en) | 2011-12-14 |
WO2010089221A1 (en) | 2010-08-12 |
IL213147A0 (en) | 2011-07-31 |
CN102307996A (zh) | 2012-01-04 |
SG173182A1 (en) | 2011-09-29 |
CA2750459A1 (en) | 2010-08-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |