EA201990698A1 - Антитела, специфические к tgf-бета - Google Patents

Антитела, специфические к tgf-бета

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Publication number
EA201990698A1
EA201990698A1 EA201990698A EA201990698A EA201990698A1 EA 201990698 A1 EA201990698 A1 EA 201990698A1 EA 201990698 A EA201990698 A EA 201990698A EA 201990698 A EA201990698 A EA 201990698A EA 201990698 A1 EA201990698 A1 EA 201990698A1
Authority
EA
Eurasian Patent Office
Prior art keywords
fibrosis
antibodies specific
beta
tgf
antibodies
Prior art date
Application number
EA201990698A
Other languages
English (en)
Inventor
Дэниел Бединджер
Ширин С. Кхан
Амер Мирза
Аджай Дж. Нарасимха
Тосихико Такеути
Original Assignee
Ксома Текнолоджи Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Ксома Текнолоджи Лтд. filed Critical Ксома Текнолоджи Лтд.
Publication of EA201990698A1 publication Critical patent/EA201990698A1/ru

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    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
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Abstract

Настоящее описание касается в основном материалов и методов для антител, специфических к трансформирующему фактору роста бета (TGFPβ), включая TGFβ1, TGFβ2 и TGFβ3, и использования этих антител при лечении субъектов, имеющих рак, глазное заболевание, состояние или нарушение, фиброз, включая офтальмический фиброз или фиброз глаз, и другие состояния или нарушения, связанные с экспрессией TGFβ.
EA201990698A 2011-06-03 2012-06-01 Антитела, специфические к tgf-бета EA201990698A1 (ru)

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Application Number Priority Date Filing Date Title
US201161493230P 2011-06-03 2011-06-03

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EA201990698A1 true EA201990698A1 (ru) 2019-12-30

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EA201391777A EA032790B1 (ru) 2011-06-03 2012-06-01 Антитела, специфические к tgf-бета
EA201990698A EA201990698A1 (ru) 2011-06-03 2012-06-01 Антитела, специфические к tgf-бета

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US (6) US8569462B2 (ru)
EP (2) EP2714735B1 (ru)
JP (5) JP6363948B2 (ru)
KR (4) KR102051014B1 (ru)
CN (3) CN103732623B (ru)
AU (4) AU2012261933B2 (ru)
BR (1) BR112013030958B1 (ru)
CA (1) CA2837556C (ru)
CY (1) CY1124610T1 (ru)
DK (1) DK2714735T3 (ru)
EA (2) EA032790B1 (ru)
ES (1) ES2894398T3 (ru)
HR (1) HRP20211582T1 (ru)
HU (1) HUE056808T2 (ru)
IL (2) IL229638B (ru)
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MY (2) MY171135A (ru)
PH (1) PH12018500401B1 (ru)
PL (1) PL2714735T3 (ru)
PT (1) PT2714735T (ru)
RS (1) RS62457B1 (ru)
SG (2) SG195253A1 (ru)
SI (1) SI2714735T1 (ru)
WO (1) WO2012167143A1 (ru)
ZA (1) ZA201309050B (ru)

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