EA201070453A1 - Экструдируемые и экструдированные композиции для доставки биологически активных агентов, способ их получения и способ их использования - Google Patents

Экструдируемые и экструдированные композиции для доставки биологически активных агентов, способ их получения и способ их использования

Info

Publication number
EA201070453A1
EA201070453A1 EA201070453A EA201070453A EA201070453A1 EA 201070453 A1 EA201070453 A1 EA 201070453A1 EA 201070453 A EA201070453 A EA 201070453A EA 201070453 A EA201070453 A EA 201070453A EA 201070453 A1 EA201070453 A1 EA 201070453A1
Authority
EA
Eurasian Patent Office
Prior art keywords
biologically active
user
delivery
extrude
receiving
Prior art date
Application number
EA201070453A
Other languages
English (en)
Other versions
EA021051B1 (ru
Inventor
Ричард К. Фуиж
Original Assignee
Филип Моррис Продактс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US12/122,201 external-priority patent/US9125434B2/en
Application filed by Филип Моррис Продактс С.А. filed Critical Филип Моррис Продактс С.А.
Publication of EA201070453A1 publication Critical patent/EA201070453A1/ru
Publication of EA021051B1 publication Critical patent/EA021051B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F47/00—Smokers' requisites not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/74—Fixation, conservation, or encapsulation of flavouring agents with a synthetic polymer matrix or excipient, e.g. vinylic, acrylic polymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/70—Fixation, conservation, or encapsulation of flavouring agents
    • A23L27/79—Fixation, conservation, or encapsulation of flavouring agents in the form of films
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00—Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/12—Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
    • A24B15/14—Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco made of tobacco and a binding agent not derived from tobacco
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B3/00—Preparing tobacco in the factory
    • A24B3/18—Other treatment of leaves, e.g. puffing, crimpling, cleaning
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Abstract

Неводная экструдируемая композиция содержит по меньшей мере один термопластичный полимер в количестве, большем чем 20 мас.% от совокупной композиции, и табак. Экструдированный биологически активный продукт в форме листа может быть получен в результате экструдирования или формования из горячего расплава неводной композиции, содержащей по меньшей мере один термопластичный полимер и биологически активный агент, при этом лист является растворимым во рту пользователя и приводит в результате к замедленному высвобождению биологически активного агента в организме пользователя. Лист для доставки биологически активного агента пользователю может иметь форму, которая может быть размещена в контакте со слизистой оболочкой пользователя и характеризуется средним временем растворения продолжительностью от 5 до 50 мин.
EA201070453A 2007-10-11 2008-10-10 Биологически активный продукт EA021051B1 (ru)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US97916907P 2007-10-11 2007-10-11
US99038107P 2007-11-27 2007-11-27
US12/122,201 US9125434B2 (en) 2007-10-11 2008-05-16 Smokeless tobacco product, smokeless tobacco product in the form of a sheet, extrudable tobacco composition, method for manufacturing a smokeless tobacco product, method for delivering super bioavailable nicotine contained in tobacco to a user, and packaged smokeless tobacco product sheet
US5419508P 2008-05-19 2008-05-19
PCT/US2008/011374 WO2009048522A1 (en) 2007-10-11 2008-10-02 Smokeless tobacco product
PCT/US2008/011634 WO2009048606A1 (en) 2007-10-11 2008-10-10 Extrudable and extruded compositions for delivery of bioactive agents, method of making the same and method of using same

Publications (2)

Publication Number Publication Date
EA201070453A1 true EA201070453A1 (ru) 2010-12-30
EA021051B1 EA021051B1 (ru) 2015-03-31

Family

ID=40549454

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201070452A EA021392B1 (ru) 2007-10-11 2008-10-02 Бездымный табачный продукт
EA201070453A EA021051B1 (ru) 2007-10-11 2008-10-10 Биологически активный продукт

Family Applications Before (1)

Application Number Title Priority Date Filing Date
EA201070452A EA021392B1 (ru) 2007-10-11 2008-10-02 Бездымный табачный продукт

Country Status (15)

Country Link
US (2) US8613285B2 (ru)
EP (2) EP2217102B1 (ru)
JP (2) JP5518720B2 (ru)
KR (3) KR101564472B1 (ru)
CN (4) CN107048483A (ru)
AU (2) AU2008311350B2 (ru)
BR (2) BRPI0818163B1 (ru)
CA (2) CA2702222C (ru)
EA (2) EA021392B1 (ru)
IL (2) IL204925A (ru)
MX (2) MX2010003928A (ru)
MY (6) MY185300A (ru)
SG (1) SG187480A1 (ru)
WO (2) WO2009048522A1 (ru)
ZA (1) ZA201002595B (ru)

Families Citing this family (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10026698A1 (de) 2000-05-30 2001-12-06 Basf Ag Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung
US8025899B2 (en) 2003-08-28 2011-09-27 Abbott Laboratories Solid pharmaceutical dosage form
US8377952B2 (en) 2003-08-28 2013-02-19 Abbott Laboratories Solid pharmaceutical dosage formulation
EP2443943A4 (en) * 2009-06-16 2014-09-03 Japan Tobacco Inc TOBACCO PRODUCT FOR ORAL USE
US9848634B2 (en) * 2009-06-30 2017-12-26 Philip Morris Products S.A. Smokeless tobacco product
JP2011016781A (ja) * 2009-07-10 2011-01-27 Tsukioka:Kk フィルム状製剤
US8360072B2 (en) * 2009-10-09 2013-01-29 Philip Morris Usa Inc. Combination treatment of tobacco extract using antioxidants and antioxidant scavengers
US8640714B2 (en) 2009-11-12 2014-02-04 Philip Morris Usa Inc. Oral chewable tobacco product and method of manufacture thereof
US20110220130A1 (en) * 2009-12-15 2011-09-15 John-Paul Mua Tobacco Product And Method For Manufacture
HUE025446T2 (en) * 2009-12-30 2016-04-28 Novartis Ag Melt extruded nicotine thin strips
SE534627C2 (sv) 2010-02-17 2011-11-01 Swedish Match North Europe Ab Orala rökfria tobaksprodukter och orala rökfria icke tobaksinnehållande snusprodukter innehållande karbamid
EP2554059B1 (en) * 2010-03-29 2015-11-25 Japan Tobacco, Inc. Oral tobacco material
CN103458715B (zh) 2010-08-05 2017-11-03 奥驰亚客户服务公司 一种无烟烟草产品以及其使用和制作方法
CN107568782B (zh) * 2010-08-05 2020-10-27 奥驰亚客户服务有限责任公司 复合无烟烟草产品、系统及方法
KR101537922B1 (ko) * 2010-08-20 2015-07-17 니뽄 다바코 산교 가부시키가이샤 담배 플래이버 방출재 및 그것을 함유하는 비가열형 담배 플래이버 흡인기
US9775376B2 (en) * 2010-12-01 2017-10-03 R.J. Reynolds Tobacco Company Smokeless tobacco pastille and moulding process for forming smokeless tobacco products
US8383135B2 (en) 2010-12-03 2013-02-26 Richard C. Fuisz Solid dosage form that promotes reliable oral, esophageal and GI transit
JP5995836B2 (ja) * 2011-03-30 2016-09-21 日本たばこ産業株式会社 口腔用たばこ及びその製造方法
CN102178337B (zh) * 2011-05-10 2013-09-04 中国烟草总公司郑州烟草研究院 一种基于造纸法再造烟叶加工特性的单独制丝工艺与设备
PT3033950T (pt) * 2011-05-31 2018-11-08 Philip Morris Products Sa Hastes para utilização em artigos para fumar
CA2838589C (en) * 2011-06-08 2019-08-20 Lts Lohmann Therapie-Systeme Ag Edible oral strip or wafer dosage form containing ion exchange resin for taste masking
US8241661B1 (en) * 2011-06-24 2012-08-14 Fuisz Richard C Biocompatible film with variable cross-sectional properties
US9474303B2 (en) * 2011-09-22 2016-10-25 R.J. Reynolds Tobacco Company Translucent smokeless tobacco product
CN103040089B (zh) * 2012-01-20 2016-08-17 奥驰亚客户服务公司 口腔用产品
AU2013204701B2 (en) * 2012-01-20 2016-12-01 Altria Client Services Llc Oral product
CN102754907B (zh) 2012-01-20 2015-06-24 奥驰亚客户服务公司 口腔用产品
CN103040090B (zh) 2012-01-20 2016-03-30 奥驰亚客户服务公司 脱除烟草的口腔用产品
US9854831B2 (en) 2012-01-20 2018-01-02 Altria Client Services Llc Oral product
CN102754908B (zh) 2012-01-20 2015-06-10 奥驰亚客户服务公司 口腔用烟草产品
CN103039688B (zh) 2012-01-20 2016-01-06 奥驰亚客户服务公司 口腔用产品
NZ626974A (en) * 2012-03-27 2016-09-30 Nicoccino Ab Nicotine formulation
EP2653042A1 (en) * 2012-04-20 2013-10-23 JT International SA pH-stabilized oral tobacco composition
UA115054C2 (uk) * 2012-04-30 2017-09-11 Філіп Морріс Продактс С.А. Тютюновий субстрат
US20130340773A1 (en) * 2012-06-22 2013-12-26 R.J. Reynolds Tobacco Company Composite tobacco-containing materials
US20140166028A1 (en) * 2012-12-14 2014-06-19 Richard C. Fuisz Enhanced Delivery of Nicotine, THC, Tobacco, Cannabidiol or Base Alkaloid from an Electronic Cigarette or Other Vapor or Smoke Producing Device Through Use of an Absorption Conditioning Unit
GB201222986D0 (en) 2012-12-20 2013-01-30 British American Tobacco Co Smokeless oral tobacco product and preparation thereof
US10779570B2 (en) 2013-01-30 2020-09-22 Philip Morris Products S.A. Aerosol from tobacco
EP2967124B1 (en) 2013-03-14 2023-05-03 Altria Client Services LLC Fiber-wrapped smokeless-tobacco product
WO2014144254A2 (en) 2013-03-15 2014-09-18 Altria Client Services Inc. Methods and machines for pouching smokeless tobacco and tobacco substitute products
CN103284318B (zh) * 2013-06-20 2015-03-11 中国烟草总公司山东省公司 一种舌下烟及其制备方法
WO2015014903A2 (en) * 2013-07-31 2015-02-05 Pharnext Diagnostic tools for alzheimer's disease
JP6149662B2 (ja) * 2013-10-03 2017-06-21 セイコーエプソン株式会社 シート製造装置、シート製造方法
WO2015068058A1 (en) 2013-11-06 2015-05-14 Rk Technology & Investments Pte. Ltd. Tobacco free 'niconuts'and the process thereof
WO2015138899A2 (en) 2014-03-14 2015-09-17 Altria Client Services Inc. Polymer encased smokeless tobacco products
EP3597052B1 (en) 2014-03-14 2023-12-27 Altria Client Services LLC Product portion enrobing process and apparatus
CA2952223C (en) * 2014-06-13 2023-08-01 United Therapeutics Corporation Treprostinil formulations
HUE040016T2 (hu) * 2014-08-20 2019-02-28 Philip Morris Products Sa Eljárás dohányspecifikus nitrózaminok mennyiségének csökkentésére nikotintartalmú folyadékokban
KR101506708B1 (ko) 2014-09-03 2015-03-30 주식회사 다림바이오텍 금연 보조용 설하분무제와 트로키를 제조하는 방법 및 이에 의하여 제조된 설하분무제와 트로키
DK3199040T3 (da) * 2014-10-24 2021-03-29 Japan Tobacco Inc Oral tobakssammensætning og fremstillingsfremgangsmåde deraf
JP6924773B2 (ja) * 2016-05-31 2021-08-25 フィリップ・モーリス・プロダクツ・ソシエテ・アノニム キャストシートの厚さをチェックするためのキャスティング装置および方法
US20180084823A1 (en) 2016-09-27 2018-03-29 BOND STREET MANUFACTURING LLC (a Florida LLC) Vaporizable Tobacco Wax Compositions and Container thereof
US10918127B2 (en) * 2016-09-27 2021-02-16 Bond Street Manufacturing Llc Vaporizable tobacco wax compositions and container thereof
US10709165B2 (en) 2016-09-27 2020-07-14 Bond Street Manufacturing Llc Vaporizable tobacco wax compositions
WO2018071415A1 (en) * 2016-10-10 2018-04-19 Purdue Research Foundation Continuous roll-to-roll freeze-drying system and process
US20180103681A1 (en) 2016-10-18 2018-04-19 Altria Client Services Llc Methods and systems for increasing stability of the pre-vapor formulation of an e-vaping device
US20180103680A1 (en) * 2016-10-18 2018-04-19 Altria Client Services Llc Methods and systems for improving stability of the pre-vapor formulation of an e-vaping device
ES2952041T3 (es) * 2016-11-22 2023-10-26 Nutrition & Biosciences Usa 4 Inc Esteres de polialfa-1,3-glucano y artículos fabricados a partir de los mismos
US11839604B2 (en) 2016-12-31 2023-12-12 Bioxcel Therapeutics, Inc. Use of sublingual dexmedetomidine for the treatment of agitation
US10238600B2 (en) 2017-04-13 2019-03-26 Richard C. Fuisz Package, system and methods for custody and control of drugs, and method and composition for making an oral soluble film, containing at least one active agent
US9901545B1 (en) 2017-04-13 2018-02-27 Richard C. Fuisz Method and composition for making an oral soluble film, containing at least one active agent
WO2019086422A1 (en) * 2017-10-31 2019-05-09 Philip Morris Products S.A. Method for producing a multilayer coated sheet including a material containing alkaloids
WO2019086462A1 (en) * 2017-10-31 2019-05-09 Philip Morris Products S.A. Sheet of a material containing alkaloids and method for producing the same
WO2019086447A1 (en) * 2017-10-31 2019-05-09 Philip Morris Products S.A. Method for producing a sheet of a material containing alkaloids and bobbin comprising the same
WO2019086412A1 (en) * 2017-10-31 2019-05-09 Philip Morris Products S.A. Method for producing a bobbin of a sheet of a material containing alkaloids and bobbin comprising the same
US11864580B2 (en) 2017-12-22 2024-01-09 G.D S.P.A. Method and unit for crimping a web of material for the tobacco industry
WO2019129861A1 (en) * 2017-12-29 2019-07-04 Philip Morris Products S.A. Method for the preparation of a sheet including a homogenized material containing alkaloids and aerosol forming article comprising a component prepared from it
KR101998288B1 (ko) * 2018-03-09 2019-07-09 (주)씨엘팜 무연 담배용 조성물 및 이를 포함하는 구강 용해 필름형 무연 담배
CN108185539B (zh) * 2018-03-21 2021-03-05 福建中烟工业有限责任公司 一种感官质量得到改善的电子烟及其制作方法
BR112020026672A2 (pt) 2018-06-27 2021-03-30 Bioxcel Therapeutics, Inc. Formulações de filme contendo dexmedetomidina e métodos para produzi-las
CA3142820A1 (en) * 2019-06-07 2020-12-10 Ncp Nextgen A/S Oral pouched product
DK180339B1 (en) 2019-06-07 2020-12-18 Ncp Nextgen As Nicotine pouch composition and pouch comprising such
KR20220049526A (ko) 2019-07-19 2022-04-21 바이오엑셀 테라퓨틱스 인코포레이티드 비-진정성 덱스메데토미딘 치료 양생법
CN112754061B (zh) * 2019-11-06 2023-07-25 秦皇岛烟草机械有限责任公司 一种烟草材料的生产工艺及生产设备
US11883527B2 (en) 2019-12-09 2024-01-30 Nicoventures Trading Limited Oral composition and method of manufacture
US11793230B2 (en) 2019-12-09 2023-10-24 Nicoventures Trading Limited Oral products with improved binding of active ingredients
US11617744B2 (en) 2019-12-09 2023-04-04 Nico Ventures Trading Limited Moist oral compositions
US11889856B2 (en) 2019-12-09 2024-02-06 Nicoventures Trading Limited Oral foam composition
US11872231B2 (en) 2019-12-09 2024-01-16 Nicoventures Trading Limited Moist oral product comprising an active ingredient
CA3160750A1 (en) 2019-12-09 2021-06-17 Anthony Richard Gerardi Oral product comprising a cannabinoid
US11826462B2 (en) 2019-12-09 2023-11-28 Nicoventures Trading Limited Oral product with sustained flavor release
US11672862B2 (en) 2019-12-09 2023-06-13 Nicoventures Trading Limited Oral products with reduced irritation
US11712059B2 (en) 2020-02-24 2023-08-01 Nicoventures Trading Limited Beaded tobacco material and related method of manufacture
US11173114B1 (en) 2020-07-10 2021-11-16 Nova Thin Film Pharmaceuticals Llc Method and system for manufacturing and oral soluble films and oral soluble films made by thereby
WO2022019029A1 (ja) * 2020-07-20 2022-01-27 日本たばこ産業株式会社 再構成たばこシートの製造装置および製造方法
US11839602B2 (en) 2020-11-25 2023-12-12 Nicoventures Trading Limited Oral cannabinoid product with lipid component
IL309950A (en) * 2021-07-09 2024-03-01 Nicoventures Trading Ltd Extracted structures
KR102432888B1 (ko) * 2022-04-11 2022-08-17 (주)벨슨 식용필름 및 이를 이용한 피부미용방법
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1492600A (en) 1921-08-20 1924-05-06 Philip B Laskey Method of making candy
US2433877A (en) 1941-10-09 1948-01-06 Int Cigar Mach Co Tobacco sheets and filaments and methods of making them
US3411515A (en) 1967-04-28 1968-11-19 Philip Morris Inc Method of preparing a reconstituted tobacco sheet employing a pectin adhesive
US3693629A (en) * 1971-06-01 1972-09-26 Brown & Williamson Tobacco Lightly prized tobacco
US3968804A (en) * 1974-05-20 1976-07-13 Amf Incorporated Extruded tobacco sheet
US4136162A (en) 1974-07-05 1979-01-23 Schering Aktiengesellschaft Medicament carriers in the form of film having active substance incorporated therein
US4144894A (en) 1977-06-29 1979-03-20 Amf Incorporated Reconstituted tobacco composition and process for manufacturing same
US4625737A (en) 1982-12-30 1986-12-02 Philip Morris Incorporated Foamed, extruded, tobacco-containing smoking article and method of making the same
US4650663A (en) 1983-07-20 1987-03-17 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates of antitussives
US4581232A (en) 1983-07-20 1986-04-08 Warner-Lambert Company Magnesium trisilicate suitable for preparation of medicament adsorbates
US4624269A (en) * 1984-09-17 1986-11-25 The Pinkerton Tobacco Company Chewable tobacco based product
US4606357A (en) * 1984-11-19 1986-08-19 Dusek Russell L Tobacco composition
AU6541786A (en) 1985-10-09 1987-05-05 Desitin Arzneimittel Gmbh Process for producing an administration or dosage form of drugs, reagents or other active ingredients
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
USRE33093E (en) 1986-06-16 1989-10-17 Johnson & Johnson Consumer Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
GB8704197D0 (en) * 1987-02-23 1987-04-01 British American Tobacco Co Tobacco reconstitution
US4855326A (en) 1987-04-20 1989-08-08 Fuisz Pharmaceutical Ltd. Rapidly dissoluble medicinal dosage unit and method of manufacture
JP2687401B2 (ja) * 1988-03-22 1997-12-08 藤沢薬品工業株式会社 内服用懸濁剤
IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorption containing ranitidine together with synthetic resin replaces cations, its preparation and pharmaceutical preparations containing it
DE4005656C2 (de) 1990-02-22 1994-05-26 Bat Cigarettenfab Gmbh Verfahren und Vorrichtung zur Herstellung einer Tabak-Folie
US20010006677A1 (en) * 1996-10-29 2001-07-05 Mcginity James W. Effervescence polymeric film drug delivery system
DE19646392A1 (de) 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
US6072100A (en) 1998-01-28 2000-06-06 Johnson & Johnson Consumer Products, Inc. Extrudable compositions for topical or transdermal drug delivery
US6596298B2 (en) 1998-09-25 2003-07-22 Warner-Lambert Company Fast dissolving orally comsumable films
US6552024B1 (en) * 1999-01-21 2003-04-22 Lavipharm Laboratories Inc. Compositions and methods for mucosal delivery
US6375963B1 (en) 1999-06-16 2002-04-23 Michael A. Repka Bioadhesive hot-melt extruded film for topical and mucosal adhesion applications and drug delivery and process for preparation thereof
US7067116B1 (en) * 2000-03-23 2006-06-27 Warner-Lambert Company Llc Fast dissolving orally consumable solid film containing a taste masking agent and pharmaceutically active agent at weight ratio of 1:3 to 3:1
DE10032456A1 (de) * 2000-07-04 2002-01-31 Lohmann Therapie Syst Lts Schnell zerfallende Darreichungsform zur Freisetzung von Wirkstoffen im Mundraum oder in Körperhöhlen
US20020168398A1 (en) * 2001-03-06 2002-11-14 Yves Delmotte Elongated biopolymer structure containing fibrin
NZ530439A (en) * 2001-04-20 2004-11-26 Lavipharm Lab Inc Intraoral delivery of nicotine for smoking cessation
DK1383400T3 (da) 2001-05-01 2008-07-07 Regent Court Technologies Llc Rögfrit tobaksprodukt
MXPA04003392A (es) 2001-10-10 2005-04-11 Gary A Tipton Proceso de recoleccion de pretratamiento de agua de desperdicio y proceso de tratamiento final.
JP5701468B2 (ja) * 2001-10-12 2015-04-15 モノソル・アールエックス・エルエルシー 自己凝集しない均一な異種性を有する薄膜、その生成方法、およびそれから製造した薬物送達系
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US7666337B2 (en) 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
DE60105820D1 (de) 2001-10-22 2004-10-28 Pera Ivo E Zusammensetzung zur Reduzierung oder Entwöhnung von Nikotinabhängigkeit
US20040037879A1 (en) 2001-11-02 2004-02-26 Adusumilli Prasad S. Oral controlled release forms useful for reducing or preventing nicotine cravings
US20030091633A1 (en) * 2001-11-15 2003-05-15 John Kelly Methods and compositions for use of (S)-bisoprolol
US20050061339A1 (en) * 2001-12-21 2005-03-24 Henri Hansson Tobacco and/or tobacco substitute composition for use as a snuff in the oral cavity
JP2004043450A (ja) * 2002-05-16 2004-02-12 Kyukyu Yakuhin Kogyo Kk 速溶性フィルム状製剤
CN100396332C (zh) * 2002-05-16 2008-06-25 救急药品工业株式会社 速溶性膜剂
US6586449B1 (en) * 2002-05-28 2003-07-01 Cambrex Charles City, Inc. Nicotine-containing, controlled release composition and method
SE0201659D0 (sv) * 2002-05-31 2002-05-31 Astrazeneca Ab Modified release pharmaceutical formulation
US20060257463A1 (en) 2002-05-31 2006-11-16 University Of Mississippi Transmucosal delivery of cannabinoids
CN1747722A (zh) * 2003-02-04 2006-03-15 赛福伦公司 无糖经口腔粘膜的固态剂型及其应用
DE10328942A1 (de) * 2003-06-27 2005-01-27 Lts Lohmann Therapie-Systeme Ag Transmukosale Darreichungsformen mit verminderter Schleimhautirritation
NO320962B1 (no) 2003-07-04 2006-02-20 Telenor Asa Anvendelse av polarisasjon for a skille ulike typer informasjon
PL2446881T3 (pl) * 2003-07-24 2014-08-29 Glaxosmithkline Llc Folie rozpuszczające się w jamie ustnej
EP1691631A4 (en) * 2003-11-07 2012-09-05 Us Smokeless Tobacco Co TOBACCO COMPOSITIONS
US8627828B2 (en) 2003-11-07 2014-01-14 U.S. Smokeless Tobacco Company Llc Tobacco compositions
US20050208108A1 (en) * 2004-03-19 2005-09-22 Jannusch Leonard C Thermoplastic films and methods for making
JP4413665B2 (ja) * 2004-03-19 2010-02-10 救急薬品工業株式会社 口腔内粘膜フィルム剤
ES2393191T3 (es) * 2004-11-30 2012-12-19 Fertin Pharma A/S Método para proporcionar un alivio rápido a un consumidor de una goma de mascar de nicotina
US20060207721A1 (en) 2005-03-17 2006-09-21 Greg Slominski Polymer adhesive splicing of water-soluble, orally ingestible thin film webs
JP5215175B2 (ja) * 2005-05-25 2013-06-19 ユーエス スモークレス タバコ カンパニー リミテッド ライアビリティ カンパニー タバコ組成物
KR100748390B1 (ko) * 2005-11-14 2007-08-10 주식회사 대웅 상피세포성장인자를 포함하는 상처치료용 서방성 필름 제형
JP5469868B2 (ja) * 2006-02-17 2014-04-16 ノバルティス アーゲー 分解可能な口腔フィルム
US8585753B2 (en) * 2006-03-04 2013-11-19 John James Scanlon Fibrillated biodegradable prosthesis
EP2010366B1 (en) * 2006-03-24 2017-03-22 Auxilium International Holdings, Inc. Process for the preparation of a hot-melt extruded laminate
US7946296B2 (en) * 2006-05-26 2011-05-24 Philip Morris Usa Inc. Dissolvable tobacco film strips and method of making the same
US20080029117A1 (en) 2006-08-01 2008-02-07 John-Paul Mua Smokeless Tobacco
EP2063864A4 (en) 2006-09-20 2012-03-14 Monosol Rx Llc EDIBLE WATER-SOLUBLE FILM CONTAINING FLAVOR-REDUCING AGENT

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CA2702222C (en) 2016-08-30
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IL204925A0 (en) 2010-11-30
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EP2205227A4 (en) 2013-07-03
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US8613285B2 (en) 2013-12-24
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