EA200501444A1 - Экспрессирующие векторы, содержащие ie2-промотор mcmv - Google Patents

Экспрессирующие векторы, содержащие ie2-промотор mcmv

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Publication number
EA200501444A1
EA200501444A1 EA200501444A EA200501444A EA200501444A1 EA 200501444 A1 EA200501444 A1 EA 200501444A1 EA 200501444 A EA200501444 A EA 200501444A EA 200501444 A EA200501444 A EA 200501444A EA 200501444 A1 EA200501444 A1 EA 200501444A1
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EA
Eurasian Patent Office
Prior art keywords
mcmv
vectors containing
expressing vectors
gene
mcmv promoter
Prior art date
Application number
EA200501444A
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English (en)
Other versions
EA010096B1 (ru
Inventor
Филипп Шателлар
Маркус Имхоф
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Апплайд Резеч Системз Арс Холдинг Н.В.
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Application filed by Апплайд Резеч Системз Арс Холдинг Н.В. filed Critical Апплайд Резеч Системз Арс Холдинг Н.В.
Publication of EA200501444A1 publication Critical patent/EA200501444A1/ru
Publication of EA010096B1 publication Critical patent/EA010096B1/ru

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    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/01DNA viruses
    • C07K14/03Herpetoviridae, e.g. pseudorabies virus
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2710/16011Herpesviridae
    • C12N2710/16111Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16141Use of virus, viral particle or viral elements as a vector
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/20Vector systems having a special element relevant for transcription transcription of more than one cistron
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    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/60Vector systems having a special element relevant for transcription from viruses

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  • Health & Medical Sciences (AREA)
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  • Plant Pathology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Настоящее изобретение относится к экспрессирующему вектору, содержащему IE2-промотор mCMV-гена, либо его фрагмент, стимулирующий функциональную экспрессию, и/или IE2-энхансер mCMV-гена, либо его фрагмент, усиливающий функциональную экспрессию, где указанный экспрессирующий вектор не содержит целого mCMV-гена.Отчет о международном поиске был опубликован 2004.11.04.
EA200501444A 2003-03-11 2004-03-10 Экспрессирующие векторы, содержащие ie2-промотор mcmv EA010096B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03100617 2003-03-11
PCT/EP2004/050280 WO2004081167A2 (en) 2003-03-11 2004-03-10 Expression vectors comprising the mcmv ie2 promoter

Publications (2)

Publication Number Publication Date
EA200501444A1 true EA200501444A1 (ru) 2006-02-24
EA010096B1 EA010096B1 (ru) 2008-06-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA200501444A EA010096B1 (ru) 2003-03-11 2004-03-10 Экспрессирующие векторы, содержащие ie2-промотор mcmv

Country Status (26)

Country Link
US (3) US7824907B2 (ru)
EP (1) EP1601776B1 (ru)
JP (3) JP5171033B2 (ru)
KR (1) KR101180139B1 (ru)
CN (1) CN100429315C (ru)
AT (1) ATE399872T1 (ru)
AU (1) AU2004219917B2 (ru)
BR (1) BRPI0408246A (ru)
CA (1) CA2516157C (ru)
CY (1) CY1108344T1 (ru)
DE (1) DE602004014738D1 (ru)
DK (1) DK1601776T3 (ru)
EA (1) EA010096B1 (ru)
ES (1) ES2309508T3 (ru)
HK (1) HK1085766A1 (ru)
HR (1) HRP20050705B1 (ru)
IL (1) IL170754A (ru)
MX (1) MXPA05009608A (ru)
NO (1) NO333818B1 (ru)
PL (1) PL1601776T4 (ru)
PT (1) PT1601776E (ru)
RS (1) RS50488B (ru)
SI (1) SI1601776T1 (ru)
UA (1) UA88138C2 (ru)
WO (1) WO2004081167A2 (ru)
ZA (1) ZA200506400B (ru)

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CN103173480B (zh) * 2013-03-01 2015-06-24 上海中医药大学附属曙光医院 一种利用双荧光素酶报告基因筛选多药耐药相关microRNA的方法
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KR102288857B1 (ko) 2013-12-20 2021-08-11 노파르티스 아게 신규한 진핵 세포 및 관심 생성물의 재조합 발현 방법
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Also Published As

Publication number Publication date
KR20050113193A (ko) 2005-12-01
HRP20050705A2 (en) 2005-12-31
KR101180139B1 (ko) 2012-09-13
ZA200506400B (en) 2006-12-27
CN100429315C (zh) 2008-10-29
EP1601776B1 (en) 2008-07-02
MXPA05009608A (es) 2006-03-21
RS50488B (sr) 2010-03-02
US20150252383A1 (en) 2015-09-10
NO20054642L (no) 2005-10-10
HRP20050705B1 (hr) 2013-08-31
JP5848202B2 (ja) 2016-01-27
CA2516157C (en) 2012-09-18
CN1759184A (zh) 2006-04-12
DK1601776T3 (da) 2008-10-13
US9051582B2 (en) 2015-06-09
PL1601776T4 (pl) 2009-05-29
JP2015180222A (ja) 2015-10-15
AU2004219917A1 (en) 2004-09-23
CA2516157A1 (en) 2004-09-23
UA88138C2 (en) 2009-09-25
JP2006520589A (ja) 2006-09-14
AU2004219917B2 (en) 2008-01-31
JP2012235787A (ja) 2012-12-06
JP5171033B2 (ja) 2013-03-27
CY1108344T1 (el) 2014-02-12
IL170754A (en) 2010-11-30
ES2309508T3 (es) 2008-12-16
PL1601776T3 (pl) 2008-12-31
DE602004014738D1 (de) 2008-08-14
BRPI0408246A (pt) 2006-03-01
WO2004081167A2 (en) 2004-09-23
US20110008839A1 (en) 2011-01-13
HK1085766A1 (en) 2006-09-01
US20070258962A1 (en) 2007-11-08
WO2004081167A3 (en) 2004-11-04
EA010096B1 (ru) 2008-06-30
EP1601776A2 (en) 2005-12-07
NO333818B1 (no) 2013-09-23
RS20050687A (en) 2007-11-15
ATE399872T1 (de) 2008-07-15
PT1601776E (pt) 2008-09-17
US7824907B2 (en) 2010-11-02
SI1601776T1 (sl) 2008-10-31

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