EA200500624A1 - Промотор для il-18bp, его получение и применение - Google Patents

Промотор для il-18bp, его получение и применение

Info

Publication number
EA200500624A1
EA200500624A1 EA200500624A EA200500624A EA200500624A1 EA 200500624 A1 EA200500624 A1 EA 200500624A1 EA 200500624 A EA200500624 A EA 200500624A EA 200500624 A EA200500624 A EA 200500624A EA 200500624 A1 EA200500624 A1 EA 200500624A1
Authority
EA
Eurasian Patent Office
Prior art keywords
promoter
preparation
application
interleukin
relates
Prior art date
Application number
EA200500624A
Other languages
English (en)
Other versions
EA007460B1 (ru
Inventor
Даниэла Новик
Менахем Рубинштейн
Владимир Хургин
Original Assignee
Йеда Рисерч Энд Дивелопмент Ко. Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Йеда Рисерч Энд Дивелопмент Ко. Лтд. filed Critical Йеда Рисерч Энд Дивелопмент Ко. Лтд.
Publication of EA200500624A1 publication Critical patent/EA200500624A1/ru
Publication of EA007460B1 publication Critical patent/EA007460B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Physics & Mathematics (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Настоящее изобретение относится к промотору белка, связывающего интерлейкин-18 (IL-18BP), к его получению и использованию.Отчет о международном поиске был опубликован 2004.05.27.
EA200500624A 2002-10-10 2003-10-09 Промотор для il-18bp, его получение и применение EA007460B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL15223202A IL152232A0 (en) 2002-10-10 2002-10-10 Promoter to il-18bp, its preparation and use
PCT/IL2003/000815 WO2004033694A2 (en) 2002-10-10 2003-10-09 Promoter to il-18bp, its preparation and use

Publications (2)

Publication Number Publication Date
EA200500624A1 true EA200500624A1 (ru) 2005-10-27
EA007460B1 EA007460B1 (ru) 2006-10-27

Family

ID=29765055

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200500624A EA007460B1 (ru) 2002-10-10 2003-10-09 Промотор для il-18bp, его получение и применение

Country Status (22)

Country Link
US (1) US7868154B2 (ru)
EP (1) EP1556412B1 (ru)
JP (1) JP4579688B2 (ru)
KR (1) KR101140498B1 (ru)
CN (1) CN100372871C (ru)
AT (1) ATE454401T1 (ru)
AU (1) AU2003269465B2 (ru)
BR (1) BR0315222A (ru)
CA (1) CA2501879C (ru)
CY (1) CY1109904T1 (ru)
DE (1) DE60330886D1 (ru)
DK (1) DK1556412T3 (ru)
EA (1) EA007460B1 (ru)
ES (1) ES2335489T3 (ru)
HK (1) HK1082510A1 (ru)
IL (2) IL152232A0 (ru)
MX (1) MXPA05003871A (ru)
NO (1) NO334018B1 (ru)
PT (1) PT1556412E (ru)
SI (1) SI1556412T1 (ru)
UA (1) UA88601C2 (ru)
WO (1) WO2004033694A2 (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2499599C2 (ru) 2007-09-28 2013-11-27 Интрексон Корпорейшн Конструкции терапевтического переключения генов и биореакторы для экспрессии биотерапевтических молекул и их применение
KR101823702B1 (ko) * 2009-12-16 2018-01-30 큐알엔에이, 인크. 막 결합 전사 인자 펩티다제, 부위 １(ｍｂｔｐｓ１)에 대한 천연 안티센스 전사체의 억제에 의한 ｍｂｔｐｓ１ 관련 질환의 치료
CN115943929A (zh) * 2015-04-13 2023-04-11 再生元制药公司 人源化SIRPα-IL15敲入小鼠及其使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4966843A (en) * 1982-11-01 1990-10-30 Cetus Corporation Expression of interferon genes in Chinese hamster ovary cells
JP2524939B2 (ja) * 1991-12-03 1996-08-14 株式会社ニチレイ エンハンサ−及びその用途
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
JP2006501839A (ja) 2006-01-19
ATE454401T1 (de) 2010-01-15
CY1109904T1 (el) 2014-09-10
DE60330886D1 (de) 2010-02-25
BR0315222A (pt) 2005-08-23
ES2335489T3 (es) 2010-03-29
HK1082510A1 (en) 2006-06-09
MXPA05003871A (es) 2005-06-22
UA88601C2 (ru) 2009-11-10
NO20051938L (no) 2005-04-20
IL167768A (en) 2012-09-24
IL152232A0 (en) 2003-05-29
US7868154B2 (en) 2011-01-11
AU2003269465B2 (en) 2007-07-12
PT1556412E (pt) 2010-02-02
CN100372871C (zh) 2008-03-05
CA2501879A1 (en) 2004-04-22
DK1556412T3 (da) 2010-04-26
NO334018B1 (no) 2013-11-18
KR20050083727A (ko) 2005-08-26
WO2004033694A2 (en) 2004-04-22
EP1556412A2 (en) 2005-07-27
KR101140498B1 (ko) 2012-04-30
SI1556412T1 (sl) 2010-03-31
US20060239984A1 (en) 2006-10-26
EA007460B1 (ru) 2006-10-27
EP1556412B1 (en) 2010-01-06
AU2003269465A1 (en) 2004-05-04
CN1726225A (zh) 2006-01-25
WO2004033694A3 (en) 2004-05-27
JP4579688B2 (ja) 2010-11-10
CA2501879C (en) 2017-08-29

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM