EA026109B1 - АГЕНТЫ, СВЯЗЫВАЮЩИЕСЯ С РЕЦЕПТОРОМ Notch1, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ - Google Patents

АГЕНТЫ, СВЯЗЫВАЮЩИЕСЯ С РЕЦЕПТОРОМ Notch1, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ Download PDF

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EA026109B1
EA026109B1 EA201170158A EA201170158A EA026109B1 EA 026109 B1 EA026109 B1 EA 026109B1 EA 201170158 A EA201170158 A EA 201170158A EA 201170158 A EA201170158 A EA 201170158A EA 026109 B1 EA026109 B1 EA 026109B1
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Prior art keywords
antibody
receptor
antibodies
cells
cancer
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EA201170158A
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English (en)
Russian (ru)
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EA201170158A1 (ru
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Остин Л. Герни
Тимоти Чарльз Хоуи
Морин Фитч Брунс
Фумико Такада Аксельрод
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Онкомед Фармасьютикалз, Инк.
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Publication of EA201170158A1 publication Critical patent/EA201170158A1/ru
Publication of EA026109B1 publication Critical patent/EA026109B1/ru

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EA201170158A 2008-07-08 2009-07-08 АГЕНТЫ, СВЯЗЫВАЮЩИЕСЯ С РЕЦЕПТОРОМ Notch1, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ EA026109B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US7909508P 2008-07-08 2008-07-08
US11269908P 2008-11-07 2008-11-07
US11270108P 2008-11-07 2008-11-07
PCT/US2009/003995 WO2010005567A2 (en) 2008-07-08 2009-07-08 Notch1 receptor binding agents and methods of use thereof

Publications (2)

Publication Number Publication Date
EA201170158A1 EA201170158A1 (ru) 2011-08-30
EA026109B1 true EA026109B1 (ru) 2017-03-31

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EA201170158A EA026109B1 (ru) 2008-07-08 2009-07-08 АГЕНТЫ, СВЯЗЫВАЮЩИЕСЯ С РЕЦЕПТОРОМ Notch1, И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
EA201170157A EA201170157A1 (ru) 2008-07-08 2009-07-08 Notch-связывающие агенты и антагонисты и способы их применения

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EA201170157A EA201170157A1 (ru) 2008-07-08 2009-07-08 Notch-связывающие агенты и антагонисты и способы их применения

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US (11) US8435513B2 (OSRAM)
EP (4) EP2307051B1 (OSRAM)
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KR (2) KR101682490B1 (OSRAM)
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EA (2) EA026109B1 (OSRAM)
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WO2007136856A2 (en) * 2006-05-19 2007-11-29 The Johns Hopkins University Heyl as a therapeutic target and a diagnostic marker for neoplasia and uses therefor
CA2655362A1 (en) 2006-06-13 2007-12-21 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
TWI419904B (zh) 2006-12-18 2013-12-21 Genentech Inc 拮抗劑抗-ｎｏｔｃｈ３抗體及其用於預防及治療ｎｏｔｃｈ３相關疾病之用途
AU2008209482B2 (en) 2007-01-24 2014-05-01 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
NZ590127A (en) 2008-07-08 2012-11-30 Oncomed Pharm Inc Notch1 receptor binding agents and methods of use thereof
US8834875B2 (en) 2010-01-13 2014-09-16 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
PE20120080A1 (es) * 2008-10-01 2012-02-17 Genentech Inc Anticuerpos anti-notch2 y metodos de uso
WO2010146550A1 (en) 2009-06-18 2010-12-23 Pfizer Inc. Anti notch-1 antibodies
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