EA015860B1 - Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа - Google Patents
Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа Download PDFInfo
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- EA015860B1 EA015860B1 EA200801071A EA200801071A EA015860B1 EA 015860 B1 EA015860 B1 EA 015860B1 EA 200801071 A EA200801071 A EA 200801071A EA 200801071 A EA200801071 A EA 200801071A EA 015860 B1 EA015860 B1 EA 015860B1
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- neutrokine
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Landscapes
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| US73596305P | 2005-11-14 | 2005-11-14 | |
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| US83415006P | 2006-07-31 | 2006-07-31 | |
| US83415206P | 2006-07-31 | 2006-07-31 | |
| PCT/US2006/038756 WO2007142667A2 (en) | 2005-10-13 | 2006-10-05 | Treatment of patients with autoantibody positive disease |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2013148049A1 (en) * | 2012-03-29 | 2013-10-03 | The General Hospital Corporation | Recombinant cytotoxic t-lymphocyte-associated protein 4 (ctla4) |
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| US8212004B2 (en) * | 1999-03-02 | 2012-07-03 | Human Genome Sciences, Inc. | Neutrokine-alpha fusion proteins |
| US6812327B1 (en) * | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| US7879328B2 (en) * | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
| EP2275449B1 (en) * | 2000-06-16 | 2016-09-28 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to BLyS |
| US20030091565A1 (en) | 2000-08-18 | 2003-05-15 | Beltzer James P. | Binding polypeptides and methods based thereon |
| US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| EA015860B1 (ru) * | 2005-10-13 | 2011-12-30 | Хьюман Дженом Сайенсиз, Инк. | Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа |
| US8211649B2 (en) | 2006-03-31 | 2012-07-03 | Human Genome Sciences, Inc. | Methods of diagnosing and prognosing hodgkin's lymphoma |
| WO2008070135A2 (en) * | 2006-12-06 | 2008-06-12 | Medimmune, Llc. | Methods of treating systemic lupus erythematosus |
| US20100261172A1 (en) * | 2007-05-03 | 2010-10-14 | Medimmune, Llc | Interferon alpha-induced pharmacodynamic markers |
| CA2685147A1 (en) * | 2007-05-03 | 2008-11-13 | Medimmune, Llc | Auto-antibody markers of autoimmune disease |
| BRPI0822447A2 (pt) | 2008-03-14 | 2015-06-16 | Biocon Ltd | Anticorpo monoclonal e método do mesmo |
| SI2291657T1 (sl) | 2008-05-01 | 2016-09-30 | Zymogenetics, Inc. | Nivoji blys/april heterotrimerjev v serumu in uporaba pri diagnostičnih postopkih |
| US10301265B2 (en) * | 2008-05-28 | 2019-05-28 | Virginia I. Roxas-Duncan | Small molecule inhibitors of botulinum neurotoxins |
| CN104398471A (zh) * | 2008-11-28 | 2015-03-11 | Abbvie公司 | 稳定的抗体组合物和用于稳定其的方法 |
| WO2010093993A2 (en) * | 2009-02-12 | 2010-08-19 | Human Genome Sciences, Inc. | Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance |
| US10005830B2 (en) | 2009-03-05 | 2018-06-26 | Ablynx N.V. | Antigen binding dimer-complexes, methods of making/avoiding and uses thereof |
| US9265834B2 (en) * | 2009-03-05 | 2016-02-23 | Ablynx N.V. | Stable formulations of polypeptides and uses thereof |
| HRP20161194T1 (hr) | 2009-03-10 | 2016-11-04 | Biogen Ma Inc. | Anti-bcma protutijela |
| WO2010126898A1 (en) * | 2009-04-27 | 2010-11-04 | The Trustees Of The University Of Pennsylvania | Methods for reducing the level of alloantibodies in a subject |
| HUE026406T2 (en) * | 2009-06-19 | 2016-06-28 | Teva Pharma | Treatment of multiple sclerosis with laquinimod |
| EP2451969A2 (en) | 2009-07-07 | 2012-05-16 | University Of Southern California | Biomarkers for the early detection of autoimmune diseases |
| CN105616410A (zh) * | 2009-07-30 | 2016-06-01 | 泰华制药工业有限公司 | 利用拉喹莫德治疗克隆氏病 |
| ES2731052T3 (es) | 2009-08-10 | 2019-11-13 | Active Biotech Ab | Tratamiento de la enfermedad de Huntington usando laquinimod |
| CN101621801B (zh) * | 2009-08-11 | 2012-11-28 | 华为终端有限公司 | 无线局域网的认证方法、系统及服务器、终端 |
| PT2473528E (pt) * | 2009-09-03 | 2015-03-04 | Ablynx NV | Formulações estáveis de polipéptidos e seus usos |
| WO2011061712A1 (en) * | 2009-11-20 | 2011-05-26 | Biocon Limited | Formulations of antibody |
| US9687523B2 (en) * | 2010-02-04 | 2017-06-27 | University Of Southern California | Compositions and methods for the treatment of sjörgren's syndrome |
| WO2011109338A1 (en) * | 2010-03-01 | 2011-09-09 | Alexion Pharmaceuticals Inc. | Methods and compositions for treating degos' disease |
| SG183515A1 (en) * | 2010-03-03 | 2012-10-30 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
| WO2011109531A1 (en) * | 2010-03-03 | 2011-09-09 | Teva Pharmaceutical Industries Ltd. | Treatment of rheumatoid arthritis with a combination of laquinimod and methotrexate |
| KR20150135552A (ko) | 2010-03-03 | 2015-12-02 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드를 이용한 루푸스 신장염의 치료 |
| US9606117B2 (en) | 2011-01-13 | 2017-03-28 | University Of Southern California | Bioassay for the early detection of autoimmune diseases |
| SG11201401330YA (en) | 2011-10-12 | 2014-05-29 | Teva Pharma | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| US9161935B2 (en) | 2012-02-03 | 2015-10-20 | Teva Pharmaceutical Industries, Ltd. | Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| US10189899B2 (en) | 2013-07-23 | 2019-01-29 | Biocon Limited | Use of a CD6 binding partner and method based thereon |
| TWI694836B (zh) | 2014-05-16 | 2020-06-01 | 英商葛蘭素史克智慧財產管理有限公司 | 抗體調配物 |
| US10039826B2 (en) * | 2015-02-09 | 2018-08-07 | Ucb Biopharma Sprl | Pharmaceutical formulation comprising antibodies which bind colony stimulating factor-1 receptor (CSF1R) |
| AR104847A1 (es) * | 2015-06-17 | 2017-08-16 | Lilly Co Eli | Formulación de anticuerpo anti-cgrp |
| EP4606820A3 (en) * | 2015-11-30 | 2025-10-29 | Medimmune, LLC | Optimized ratios of amino acids and sugars as amorphous stabilizing compounds in pharmaceutical compositions containing high concentrations of protein-based therapeutic agents |
| US11242401B2 (en) | 2016-10-21 | 2022-02-08 | Biocon Limited | Monoclonal antibody and a method of use for the treatment of lupus |
| BR112019010064A2 (pt) | 2016-11-18 | 2019-10-01 | Astellas Pharma Inc | novo fragmento fab do anticorpo muc1 anti-humano |
| WO2018127914A1 (en) * | 2017-01-05 | 2018-07-12 | Yeda Research And Development Co. Ltd. | Peptides for treating sjogren's syndrome |
| KR20240042244A (ko) | 2017-05-19 | 2024-04-01 | 신닥스 파마슈티컬스, 인크. | 조합 요법 |
| TWI795415B (zh) | 2017-07-07 | 2023-03-11 | 日商安斯泰來製藥股份有限公司 | 新穎的抗人類ＣＥＡＣＡＭ５抗體Ｆａｂ片段 |
| BR112020023420A8 (pt) | 2018-05-17 | 2022-07-05 | Astellas Pharma Inc | Complexo tendo fragmento fab de anticorpo anti-muc1 humano, peptídeo ligador e/ou ligante |
| EP3865154A4 (en) * | 2018-10-10 | 2022-11-09 | Astellas Pharma Inc. | PHARMACEUTICAL COMPOSITION CONTAINING ANTIBODY FAB FRAGMENT COMPLEX AT LABELED ANTI-HUMAN SITE |
| MX2021009851A (es) | 2019-02-18 | 2021-09-10 | Lilly Co Eli | Formulacion de anticuerpos terapeuticos. |
| CN115812077A (zh) * | 2020-05-08 | 2023-03-17 | 高山免疫科学股份有限公司 | April和baff抑制性免疫调节蛋白及其使用方法 |
| JP2023527563A (ja) * | 2020-05-29 | 2023-06-29 | チヌーク セラピューティクス，インコーポレイテッド | ＡＰＲＩＬ結合抗体によるＩｇＡ腎症を治療する方法 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013148049A1 (en) * | 2012-03-29 | 2013-10-03 | The General Hospital Corporation | Recombinant cytotoxic t-lymphocyte-associated protein 4 (ctla4) |
| US9758566B2 (en) | 2012-03-29 | 2017-09-12 | The General Hospital Corporation | Recombinant cytotoxic T-lymphocyte-associated protein 4 (CTLA4) |
Also Published As
| Publication number | Publication date |
|---|---|
| NZ597082A (en) | 2013-11-29 |
| JP5905184B2 (ja) | 2016-04-20 |
| EP1933873A4 (en) | 2009-12-02 |
| JP2013040207A (ja) | 2013-02-28 |
| NO20081842L (no) | 2008-07-08 |
| KR20080074120A (ko) | 2008-08-12 |
| CA2626082A1 (en) | 2007-12-13 |
| CA2626082C (en) | 2017-04-11 |
| EA200801071A1 (ru) | 2008-10-30 |
| IL190733A0 (en) | 2008-11-03 |
| WO2007142667A2 (en) | 2007-12-13 |
| IL217632A (en) | 2013-06-27 |
| US20090081213A1 (en) | 2009-03-26 |
| NZ568204A (en) | 2012-01-12 |
| AU2006344395A1 (en) | 2007-12-13 |
| US20070086979A1 (en) | 2007-04-19 |
| EP1933873A2 (en) | 2008-06-25 |
| WO2007142667A3 (en) | 2008-12-18 |
| US20090081231A1 (en) | 2009-03-26 |
| JP2009521398A (ja) | 2009-06-04 |
| JP5936994B2 (ja) | 2016-06-22 |
| KR20140077946A (ko) | 2014-06-24 |
| JP2013032402A (ja) | 2013-02-14 |
| HK1222681A1 (en) | 2017-07-07 |
| AU2006344395B2 (en) | 2013-05-02 |
| EP3037544A1 (en) | 2016-06-29 |
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