AU2006344395B2 - Methods and compositions for use in treatment of patients with autoantibody positive diseases - Google Patents

Methods and compositions for use in treatment of patients with autoantibody positive diseases Download PDF

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Publication number
AU2006344395B2
AU2006344395B2 AU2006344395A AU2006344395A AU2006344395B2 AU 2006344395 B2 AU2006344395 B2 AU 2006344395B2 AU 2006344395 A AU2006344395 A AU 2006344395A AU 2006344395 A AU2006344395 A AU 2006344395A AU 2006344395 B2 AU2006344395 B2 AU 2006344395B2
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Australia
Prior art keywords
neutrokine
alpha
patient
antagonist
specific embodiment
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AU2006344395A
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English (en)
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AU2006344395A1 (en
Inventor
Marc Chevrier
William Friemuth
Daniel Odenheimer
Melissa D. Perkins
Zhenshao Zhong
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GlaxoSmithKline Intellectual Property Development Ltd
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GlaxoSmithKline Intellectual Property Development Ltd
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38801932&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AU2006344395(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by GlaxoSmithKline Intellectual Property Development Ltd filed Critical GlaxoSmithKline Intellectual Property Development Ltd
Publication of AU2006344395A1 publication Critical patent/AU2006344395A1/en
Priority to AU2013205399A priority Critical patent/AU2013205399A1/en
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Assigned to GLAXOSMITHKLINE INTELLECTUAL PROPERTY LIMITED reassignment GLAXOSMITHKLINE INTELLECTUAL PROPERTY LIMITED Request for Assignment Assignors: HUMAN GENOME SCIENCES, INC.
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Neurosurgery (AREA)
  • Cell Biology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
AU2006344395A 2005-10-13 2006-10-05 Methods and compositions for use in treatment of patients with autoantibody positive diseases Active AU2006344395B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2013205399A AU2013205399A1 (en) 2005-10-13 2013-04-23 Methods and compositions for use in treatment of patients with autoantibody positive diseases

Applications Claiming Priority (53)

Application Number Priority Date Filing Date Title
US72562605P 2005-10-13 2005-10-13
US72562705P 2005-10-13 2005-10-13
US72562905P 2005-10-13 2005-10-13
US72562505P 2005-10-13 2005-10-13
US72562805P 2005-10-13 2005-10-13
US60/725,629 2005-10-13
US60/725,625 2005-10-13
US60/725,628 2005-10-13
US60/725,627 2005-10-13
US60/725,626 2005-10-13
US73596705P 2005-11-14 2005-11-14
US73598805P 2005-11-14 2005-11-14
US73596305P 2005-11-14 2005-11-14
US73596405P 2005-11-14 2005-11-14
US73598705P 2005-11-14 2005-11-14
US60/735,987 2005-11-14
US60/735,967 2005-11-14
US60/735,988 2005-11-14
US60/735,963 2005-11-14
US60/735,964 2005-11-14
US77665906P 2006-02-27 2006-02-27
US77666506P 2006-02-27 2006-02-27
US77665806P 2006-02-27 2006-02-27
US77666006P 2006-02-27 2006-02-27
US77666406P 2006-02-27 2006-02-27
US60/776,659 2006-02-27
US60/776,665 2006-02-27
US60/776,660 2006-02-27
US60/776,664 2006-02-27
US60/776,658 2006-02-28
US78138706P 2006-03-13 2006-03-13
US60/781,387 2006-03-13
US78755706P 2006-03-31 2006-03-31
US60/787,557 2006-03-31
US79736006P 2006-05-04 2006-05-04
US79735106P 2006-05-04 2006-05-04
US60/797,351 2006-05-04
US60/797,360 2006-05-04
US81487006P 2006-06-20 2006-06-20
US81486906P 2006-06-20 2006-06-20
US60/814,869 2006-06-20
US60/814,870 2006-06-20
US81555906P 2006-06-22 2006-06-22
US81555806P 2006-06-22 2006-06-22
US60/815,559 2006-06-22
US60/815,558 2006-06-22
US81582706P 2006-06-23 2006-06-23
US60/815,827 2006-06-23
US83415206P 2006-07-31 2006-07-31
US83415006P 2006-07-31 2006-07-31
US60/834,152 2006-07-31
US60/834,150 2006-07-31
PCT/US2006/038756 WO2007142667A2 (en) 2005-10-13 2006-10-05 Treatment of patients with autoantibody positive disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2013205399A Division AU2013205399A1 (en) 2005-10-13 2013-04-23 Methods and compositions for use in treatment of patients with autoantibody positive diseases

Publications (2)

Publication Number Publication Date
AU2006344395A1 AU2006344395A1 (en) 2007-12-13
AU2006344395B2 true AU2006344395B2 (en) 2013-05-02

Family

ID=38801932

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006344395A Active AU2006344395B2 (en) 2005-10-13 2006-10-05 Methods and compositions for use in treatment of patients with autoantibody positive diseases

Country Status (12)

Country Link
US (3) US20070086979A1 (enExample)
EP (2) EP3037544A1 (enExample)
JP (3) JP5905184B2 (enExample)
KR (2) KR20080074120A (enExample)
AU (1) AU2006344395B2 (enExample)
CA (1) CA2626082C (enExample)
EA (1) EA015860B1 (enExample)
HK (1) HK1222681A1 (enExample)
IL (2) IL190733A0 (enExample)
NO (1) NO20081842L (enExample)
NZ (2) NZ568204A (enExample)
WO (1) WO2007142667A2 (enExample)

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