AU4988697A - Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents - Google Patents

Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents

Info

Publication number
AU4988697A
AU4988697A AU49886/97A AU4988697A AU4988697A AU 4988697 A AU4988697 A AU 4988697A AU 49886/97 A AU49886/97 A AU 49886/97A AU 4988697 A AU4988697 A AU 4988697A AU 4988697 A AU4988697 A AU 4988697A
Authority
AU
Australia
Prior art keywords
beta
fd4c
fddc
antiviral agents
potent antiviral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU49886/97A
Inventor
Ellen Carmichael
Shu-Hui Chen
Yung-Chi Cheng
Terrence W. Doyle
Xiuyan Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Vion Pharmaceuticals Inc
Original Assignee
Yale University
Vion Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yale University, Vion Pharmaceuticals Inc filed Critical Yale University
Publication of AU4988697A publication Critical patent/AU4988697A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
AU49886/97A 1996-10-24 1997-10-23 Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents Abandoned AU4988697A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73615696A 1996-10-24 1996-10-24
US08736156 1996-10-24
PCT/US1997/018860 WO1998017281A1 (en) 1996-10-24 1997-10-23 MONOPHOSPHATE PRODRUGS OF β-L-FD4C AND β-L-FddC AS POTENT ANTIVIRAL AGENTS

Publications (1)

Publication Number Publication Date
AU4988697A true AU4988697A (en) 1998-05-15

Family

ID=24958728

Family Applications (1)

Application Number Title Priority Date Filing Date
AU49886/97A Abandoned AU4988697A (en) 1996-10-24 1997-10-23 Monophosphate prodrugs of beta-l-fd4c and beta-l-fddc as potent antiviral agents

Country Status (2)

Country Link
AU (1) AU4988697A (en)
WO (1) WO1998017281A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7361400A (en) * 1999-09-08 2001-04-10 Metabasis Therapeutics, Inc. Prodrugs for liver specific drug delivery
CA2747325A1 (en) 2000-04-12 2001-10-25 Human Genome Sciences, Inc. Albumin fusion proteins
CA2413160A1 (en) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Human tumor necrosis factor delta and epsilon
KR100978904B1 (en) * 2001-12-14 2010-08-31 파마셋 인코포레이티드 N4-Acylcytosine nucleosides for treatment of viral infections
ES2425738T3 (en) 2001-12-21 2013-10-17 Human Genome Sciences, Inc. Albumin Fusion Proteins
US20040157793A1 (en) * 2002-11-12 2004-08-12 Stuyver Lieven J. Modified nucleosides as antiviral agents
US7892563B2 (en) 2003-05-20 2011-02-22 Wyeth Holdings Corporation Methods for treatment of severe acute respiratory syndrome (SARS)
JP5905184B2 (en) 2005-10-13 2016-04-20 ヒューマン ジノーム サイエンシーズ， インコーポレイテッドＨｕｍａｎ Ｇｅｎｏｍｅ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． Methods and compositions for use in treating patients with autoantibody positive disease
US8076303B2 (en) 2005-12-13 2011-12-13 Spring Bank Pharmaceuticals, Inc. Nucleotide and oligonucleotide prodrugs
US8076476B2 (en) 2007-11-15 2011-12-13 Avi Biopharma, Inc. Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits
US8299206B2 (en) 2007-11-15 2012-10-30 Avi Biopharma, Inc. Method of synthesis of morpholino oligomers
US8729058B2 (en) 2009-10-27 2014-05-20 Michael Zasloff Methods and compositions for treating and preventing viral infections
WO2011066260A2 (en) 2009-11-25 2011-06-03 Michael Zasloff Formulations comprising aminosterols
CN108239128B (en) 2016-12-23 2019-03-29 江苏奥赛康药业股份有限公司 The preparation method of beta-nucleosides class compound

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW374087B (en) * 1993-05-25 1999-11-11 Univ Yale L-2',3'-dideoxy nucleotide analogs as anti-hepatitis B(HBV) and anti-HIV agents

Also Published As

Publication number Publication date
WO1998017281A1 (en) 1998-04-30

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