IL122642A0 - Substituted purine derivatives processes for their preparation their use and compositions comprising them - Google Patents

Substituted purine derivatives processes for their preparation their use and compositions comprising them

Info

Publication number
IL122642A0
IL122642A0 IL12264297A IL12264297A IL122642A0 IL 122642 A0 IL122642 A0 IL 122642A0 IL 12264297 A IL12264297 A IL 12264297A IL 12264297 A IL12264297 A IL 12264297A IL 122642 A0 IL122642 A0 IL 122642A0
Authority
IL
Israel
Prior art keywords
compositions
preparation
purine derivatives
substituted purine
derivatives processes
Prior art date
Application number
IL12264297A
Original Assignee
Hoechst Ag
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Genentech Inc filed Critical Hoechst Ag
Publication of IL122642A0 publication Critical patent/IL122642A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL12264297A 1996-12-20 1997-12-18 Substituted purine derivatives processes for their preparation their use and compositions comprising them IL122642A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19653646A DE19653646A1 (en) 1996-12-20 1996-12-20 Substituted purine derivatives, processes for their preparation, agents containing them and their use

Publications (1)

Publication Number Publication Date
IL122642A0 true IL122642A0 (en) 1998-08-16

Family

ID=7815761

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12264297A IL122642A0 (en) 1996-12-20 1997-12-18 Substituted purine derivatives processes for their preparation their use and compositions comprising them

Country Status (22)

Country Link
EP (1) EP0853084B1 (en)
JP (1) JP4620190B2 (en)
KR (1) KR19980064655A (en)
CN (2) CN1101816C (en)
AR (1) AR010700A1 (en)
AT (1) ATE404562T1 (en)
AU (1) AU728865B2 (en)
BR (1) BR9706387A (en)
CA (1) CA2225366C (en)
CZ (1) CZ294437B6 (en)
DE (2) DE19653646A1 (en)
HK (1) HK1012190A1 (en)
HU (1) HUP9702507A3 (en)
ID (1) ID19254A (en)
IL (1) IL122642A0 (en)
NO (1) NO314583B1 (en)
NZ (1) NZ329431A (en)
PL (1) PL323969A1 (en)
RU (1) RU2228335C2 (en)
TR (1) TR199701647A2 (en)
TW (1) TW523515B (en)
ZA (1) ZA9711317B (en)

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CN1140511C (en) 1998-04-09 2004-03-03 明治制果株式会社 Amino piperidine derivatives as integrin alpha beta 3 antagonists
WO2000038715A2 (en) 1998-12-23 2000-07-06 G.D. Searle & Co. Use of an integrin antagonist and radiation in the treatment of neoplasia
JP3270834B2 (en) 1999-01-27 2002-04-02 ファイザー・プロダクツ・インク Heteroaromatic bicyclic derivatives useful as anticancer agents
UA71945C2 (en) 1999-01-27 2005-01-17 Pfizer Prod Inc Substituted bicyclic derivatives being used as anticancer agents
EP1065207A1 (en) 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
EP1065208A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Substituted purine derivatives as inhibitors of cell adhesion
WO2001010844A1 (en) 1999-08-05 2001-02-15 Meiji Seika Kaisha, Ltd. φ-AMINO-α-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN αvβ3 ANTAGONISM
EP1176145A1 (en) 2000-07-28 2002-01-30 Aventis Pharma Deutschland GmbH Novel guanidino derivatives as inhibitors of cell adhesion
DE10042655A1 (en) * 2000-08-31 2002-03-14 Aventis Pharma Gmbh Process for the preparation of inhibitors of cell adhesion
KR100438820B1 (en) * 2001-03-05 2004-07-05 삼성코닝 주식회사 Method for manufacturing compound semiconductor substrate of III-V group
AU2002316855B2 (en) 2001-04-24 2008-03-13 Merck Patent Gmbh Combination therapy using anti-angiogenic agents and TNFalpha
FR2847254B1 (en) 2002-11-19 2005-01-28 Aventis Pharma Sa NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, PROCESS FOR PREPARING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS REFLECTING THEM
FR2870541B1 (en) 2004-05-18 2006-07-14 Proskelia Sas ANTIGONISTIC PYRIMIDINE DERIVATIVES OF VITRONECTIN RECEPTOR
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
ES2425396T3 (en) 2006-01-18 2013-10-15 Merck Patent Gmbh Specific therapy using integrin ligands for cancer treatment
DK2101805T3 (en) 2007-01-18 2013-01-21 Merck Patent Gmbh INTEGRIC LANDS FOR USE IN CANCER TREATMENT
HUE025262T2 (en) * 2007-10-11 2016-02-29 Daiichi Sankyo Co Ltd ANTIBODY TARGETING OSTEOCLAST-RELATED PROTEIN Siglec-15
WO2009065035A1 (en) * 2007-11-14 2009-05-22 Myriad Genetics, Inc. Therapeutic compounds and their use in treating diseases and disorders
KR101690340B1 (en) 2009-04-09 2016-12-27 다이이찌 산쿄 가부시키가이샤 ANTI-Siglec-15 ANTIBODY
JP2012528079A (en) 2009-05-25 2012-11-12 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Continuous administration of integrin ligand to treat cancer
MX2013003828A (en) 2010-10-05 2013-06-28 Daiichi Sankyo Co Ltd Antibody targeting osteoclast-related protein siglec-15.
ES2660472T3 (en) 2012-03-30 2018-03-22 Daiichi Sankyo Company, Limited Anti-Siglec-15 antibody modified with CDR
CN103665043B (en) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 A kind of tenofovir prodrug and its application in medicine
US10328082B2 (en) 2014-05-30 2019-06-25 Pfizer Inc. Methods of use and combinations
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (21)

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JPS4730696Y1 (en) * 1966-12-10 1972-09-13
JPS6396663A (en) * 1986-10-13 1988-04-27 Mita Ind Co Ltd Electrostatic charge image developing toner
JPS6396553A (en) * 1986-10-14 1988-04-27 Sekisui Chem Co Ltd Packing material
DE4129603A1 (en) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K CONDENSED 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THESE COMPOUNDS
MX9207334A (en) * 1991-12-18 1993-08-01 Glaxo Inc NUCLEIC ACIDS PEPTIDICS AND PHARMACEUTICAL FORMULATION CONTAINING THEM
FR2700337B1 (en) * 1993-01-11 1995-04-14 Lafon Labor Imidazopyridine-2-one derivatives, their preparation process and their use in therapy.
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
DE4405378A1 (en) * 1994-02-19 1995-08-24 Merck Patent Gmbh Adhesion receptor antagonists
US5554746A (en) * 1994-05-16 1996-09-10 Isis Pharmaceuticals, Inc. Lactam nucleic acids
US5929046A (en) * 1994-06-08 1999-07-27 Cancer Research Campaign Technology Limited Pyrimidine and purine derivatives and their use in treating tumour cells
US5994361A (en) * 1994-06-22 1999-11-30 Biochem Pharma Substituted purinyl derivatives with immunomodulating activity
JPH10504808A (en) * 1994-06-29 1998-05-12 スミスクライン・ビーチャム・コーポレイション Vitronectin receptor antagonist
US5525606A (en) * 1994-08-01 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
AU4729796A (en) * 1994-12-28 1996-07-19 Peter E. Nielsen Peptide nucleic acid incorporating a chiral backbone
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
EP0840741B1 (en) * 1995-06-07 2004-04-28 Perseptive Biosystems, Inc. Pna-dna chimeras and pna synthons for their preparation
EP0901476A4 (en) * 1996-03-26 2001-08-16 Du Pont Pharm Co Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
JPH1025294A (en) * 1996-03-26 1998-01-27 Akira Matsuda Condensed heterocyclic derivative, its production and malignant tumor therapeutic agent containing the same
GB9613021D0 (en) * 1996-06-21 1996-08-28 Pharmacia Spa Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
CA2261566A1 (en) * 1996-07-24 1998-01-29 Buchardt, Dorte Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2

Also Published As

Publication number Publication date
CN1101816C (en) 2003-02-19
ATE404562T1 (en) 2008-08-15
ID19254A (en) 1998-06-28
HUP9702507A3 (en) 1999-12-28
RU2228335C2 (en) 2004-05-10
HK1012190A1 (en) 1999-07-30
PL323969A1 (en) 1998-06-22
KR19980064655A (en) 1998-10-07
CA2225366A1 (en) 1998-06-20
EP0853084A3 (en) 1998-09-09
CN1495184A (en) 2004-05-12
DE19653646A1 (en) 1998-06-25
ZA9711317B (en) 1998-06-22
DE59712958D1 (en) 2008-09-25
AR010700A1 (en) 2000-06-28
MX9710277A (en) 1998-10-31
CZ294437B6 (en) 2005-01-12
TW523515B (en) 2003-03-11
JP4620190B2 (en) 2011-01-26
TR199701647A3 (en) 1998-07-21
NO975977L (en) 1998-06-22
EP0853084A2 (en) 1998-07-15
AU728865B2 (en) 2001-01-18
AU4846697A (en) 1998-06-25
NO314583B1 (en) 2003-04-14
CZ411497A3 (en) 1998-07-15
JPH10182645A (en) 1998-07-07
BR9706387A (en) 2000-03-14
CA2225366C (en) 2006-10-10
CN1193623A (en) 1998-09-23
EP0853084B1 (en) 2008-08-13
TR199701647A2 (en) 1998-07-21
NO975977D0 (en) 1997-12-19
HUP9702507A2 (en) 1999-05-28
HU9702507D0 (en) 1998-03-02
NZ329431A (en) 2000-01-28

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