IL122642A0 - Substituted purine derivatives processes for their preparation their use and compositions comprising them - Google Patents

Substituted purine derivatives processes for their preparation their use and compositions comprising them

Info

Publication number
IL122642A0
IL122642A0 IL12264297A IL12264297A IL122642A0 IL 122642 A0 IL122642 A0 IL 122642A0 IL 12264297 A IL12264297 A IL 12264297A IL 12264297 A IL12264297 A IL 12264297A IL 122642 A0 IL122642 A0 IL 122642A0
Authority
IL
Israel
Prior art keywords
compositions
preparation
purine derivatives
substituted purine
derivatives processes
Prior art date
Application number
IL12264297A
Original Assignee
Hoechst Ag
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Genentech Inc filed Critical Hoechst Ag
Publication of IL122642A0 publication Critical patent/IL122642A0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
IL12264297A 1996-12-20 1997-12-18 Substituted purine derivatives processes for their preparation their use and compositions comprising them IL122642A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19653646A DE19653646A1 (en) 1996-12-20 1996-12-20 Substituted purine derivatives, processes for their preparation, agents containing them and their use

Publications (1)

Publication Number Publication Date
IL122642A0 true IL122642A0 (en) 1998-08-16

Family

ID=7815761

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12264297A IL122642A0 (en) 1996-12-20 1997-12-18 Substituted purine derivatives processes for their preparation their use and compositions comprising them

Country Status (22)

Country Link
EP (1) EP0853084B1 (en)
JP (1) JP4620190B2 (en)
KR (1) KR19980064655A (en)
CN (2) CN1101816C (en)
AR (1) AR010700A1 (en)
AT (1) ATE404562T1 (en)
AU (1) AU728865B2 (en)
BR (1) BR9706387A (en)
CA (1) CA2225366C (en)
CZ (1) CZ294437B6 (en)
DE (2) DE19653646A1 (en)
HK (1) HK1012190A1 (en)
HU (1) HUP9702507A3 (en)
ID (1) ID19254A (en)
IL (1) IL122642A0 (en)
NO (1) NO314583B1 (en)
NZ (1) NZ329431A (en)
PL (1) PL323969A1 (en)
RU (1) RU2228335C2 (en)
TR (1) TR199701647A2 (en)
TW (1) TW523515B (en)
ZA (1) ZA9711317B (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1074543B1 (en) 1998-04-09 2012-01-25 Meiji Seika Pharma Co., Ltd. Aminopiperidine derivatives as integrin alpha v beta 3 antagonists
CA2356748A1 (en) 1998-12-23 2000-07-06 G.D. Searle & Co. Method of using an integrin antagonist and radiation therapy as combination therapy in the treatment of neoplasia
JP3270834B2 (en) 1999-01-27 2002-04-02 ファイザー・プロダクツ・インク Heteroaromatic bicyclic derivatives useful as anticancer agents
UA71945C2 (en) 1999-01-27 2005-01-17 Pfizer Prod Inc Substituted bicyclic derivatives being used as anticancer agents
EP1065208A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Substituted purine derivatives as inhibitors of cell adhesion
EP1065207A1 (en) 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
AU6316900A (en) 1999-08-05 2001-03-05 Meiji Seika Kaisha Ltd. Omega-amino-alpha-hydroxycarboxylic acid derivatives having integrin alphavbeta3antagonism
EP1176145A1 (en) * 2000-07-28 2002-01-30 Aventis Pharma Deutschland GmbH Novel guanidino derivatives as inhibitors of cell adhesion
DE10042655A1 (en) 2000-08-31 2002-03-14 Aventis Pharma Gmbh Process for the preparation of inhibitors of cell adhesion
KR100438820B1 (en) * 2001-03-05 2004-07-05 삼성코닝 주식회사 Method for manufacturing compound semiconductor substrate of III-V group
AU2002316855B2 (en) 2001-04-24 2008-03-13 Merck Patent Gmbh Combination therapy using anti-angiogenic agents and TNFalpha
FR2847254B1 (en) * 2002-11-19 2005-01-28 Aventis Pharma Sa NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, PROCESS FOR PREPARING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS REFLECTING THEM
FR2870541B1 (en) 2004-05-18 2006-07-14 Proskelia Sas ANTIGONISTIC PYRIMIDINE DERIVATIVES OF VITRONECTIN RECEPTOR
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
CA2637387A1 (en) 2006-01-18 2007-07-26 Simon Goodman Specific therapy using integrin ligands for treating cancer
WO2008087025A2 (en) 2007-01-18 2008-07-24 Merck Patent Gmbh Specific therapy and medicament using integrin ligands for treating cancer
DK2206727T3 (en) 2007-10-11 2015-07-06 Daiichi Sankyo Co Ltd ANTIBODY SPECIFIC TO OSTEOKLASTRELATERET PROTEIN Siglec-15
JP2011503206A (en) * 2007-11-14 2011-01-27 ミレクシス， インコーポレイテッド Therapeutic compounds and methods of use thereof in the treatment of diseases and disorders
AU2010235453B2 (en) 2009-04-09 2013-10-03 Daiichi Sankyo Company,Limited Anti-Siglec-15 antibody
US20120130146A1 (en) 2009-05-25 2012-05-24 Merck Patent Gmbh Continuous administration of cilengitide in cancer treatments
EP2625205A2 (en) 2010-10-05 2013-08-14 Daiichi Sankyo Company, Limited Antibody targeting osteoclast-related protein siglec-15
SG11201405966PA (en) 2012-03-30 2014-11-27 Daiichi Sankyo Co Ltd Cdr-modified anti-siglec-15 antibody
CN103665043B (en) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 A kind of tenofovir prodrug and its application in medicine
RU2016146826A (en) 2014-05-30 2018-07-04 Пфайзер Инк. CARBONITRIL DERIVATIVES AS SELECTIVE ANDROGEN RECEPTOR MODULATORS
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4730696Y1 (en) * 1966-12-10 1972-09-13
JPS6396663A (en) * 1986-10-13 1988-04-27 Mita Ind Co Ltd Electrostatic charge image developing toner
JPS6396553A (en) * 1986-10-14 1988-04-27 Sekisui Chem Co Ltd Packing material
DE4129603A1 (en) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K CONDENSED 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THESE COMPOUNDS
MX9207334A (en) * 1991-12-18 1993-08-01 Glaxo Inc NUCLEIC ACIDS PEPTIDICS AND PHARMACEUTICAL FORMULATION CONTAINING THEM
FR2700337B1 (en) * 1993-01-11 1995-04-14 Lafon Labor Imidazopyridine-2-one derivatives, their preparation process and their use in therapy.
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
DE4405378A1 (en) * 1994-02-19 1995-08-24 Merck Patent Gmbh Adhesion receptor antagonists
US5554746A (en) * 1994-05-16 1996-09-10 Isis Pharmaceuticals, Inc. Lactam nucleic acids
US5929046A (en) * 1994-06-08 1999-07-27 Cancer Research Campaign Technology Limited Pyrimidine and purine derivatives and their use in treating tumour cells
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
JPH10504808A (en) * 1994-06-29 1998-05-12 スミスクライン・ビーチャム・コーポレイション Vitronectin receptor antagonist
US5525606A (en) * 1994-08-01 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
WO1996020212A2 (en) * 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
JP2001518054A (en) * 1995-06-07 2001-10-09 パーセプティブ バイオシステムズ，インコーポレーテッド PNA-DNA chimera and PNA synthon for chimera synthesis
JPH1025294A (en) * 1996-03-26 1998-01-27 Akira Matsuda Condensed heterocyclic derivative, its production and malignant tumor therapeutic agent containing the same
EP0901476A4 (en) * 1996-03-26 2001-08-16 Du Pont Pharm Co Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
GB9613021D0 (en) * 1996-06-21 1996-08-28 Pharmacia Spa Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
DE69734783T2 (en) * 1996-07-24 2006-08-17 Buchardt, Dorte PEPTID NUCLEIC ACIDS WITH INCREASED BINDING SAFFINITY, SEQUENCE SPECIFICITY AND SOLUBILITY
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2

Also Published As

Publication number Publication date
CA2225366C (en) 2006-10-10
CZ411497A3 (en) 1998-07-15
HUP9702507A2 (en) 1999-05-28
AU4846697A (en) 1998-06-25
NO314583B1 (en) 2003-04-14
JP4620190B2 (en) 2011-01-26
CA2225366A1 (en) 1998-06-20
BR9706387A (en) 2000-03-14
DE19653646A1 (en) 1998-06-25
NO975977L (en) 1998-06-22
AR010700A1 (en) 2000-06-28
AU728865B2 (en) 2001-01-18
NO975977D0 (en) 1997-12-19
ID19254A (en) 1998-06-28
TR199701647A3 (en) 1998-07-21
NZ329431A (en) 2000-01-28
HU9702507D0 (en) 1998-03-02
EP0853084A2 (en) 1998-07-15
HUP9702507A3 (en) 1999-12-28
KR19980064655A (en) 1998-10-07
CN1101816C (en) 2003-02-19
TR199701647A2 (en) 1998-07-21
ZA9711317B (en) 1998-06-22
MX9710277A (en) 1998-10-31
EP0853084A3 (en) 1998-09-09
CZ294437B6 (en) 2005-01-12
JPH10182645A (en) 1998-07-07
HK1012190A1 (en) 1999-07-30
TW523515B (en) 2003-03-11
PL323969A1 (en) 1998-06-22
DE59712958D1 (en) 2008-09-25
ATE404562T1 (en) 2008-08-15
CN1495184A (en) 2004-05-12
CN1193623A (en) 1998-09-23
RU2228335C2 (en) 2004-05-10
EP0853084B1 (en) 2008-08-13

Similar Documents

Publication Publication Date Title
IL122642A0 (en) Substituted purine derivatives processes for their preparation their use and compositions comprising them
AP9901556A0 (en) Sulpponamide derivatives process for their preparation and their use as medicaments
HK1016580A1 (en) Purine derivatives and processes for their preparation
ZA968322B (en) Solid sillicone compositions and methods for their preparation and use
GB2326093B (en) Avermectin formulation
AP9801369A0 (en) Dispersible macromole-cule compositions and methods for their preparation and use
IL118825A (en) Substituted 6-dimethylaminomethyl-1-phenyl-cyclohexane derivatives their preparation and use
HK1112180A1 (en) Pharmaceutical use and compositions involving isoflavones
IL116066A0 (en) Controlled release caffeine composition and its preparation
IL116851A0 (en) 3-arylidene-2-oxindole derivatives their preparation and use
IL126381A (en) Heterocyclic azahexane derivatives and antiviral compositions containing them
IL114795A0 (en) N-benzylindole- and benmzopyrazole derivatives their preparation and use
IL136308A0 (en) Antipicornaviral compounds and methods for their use and preparation
IL129089A0 (en) New derivatives from piperidine-keto acid their preparation and use
IL125710A0 (en) Arylglycinamide derivatives their preparation and pharmaceutical compositions containing them
HUP9904694A3 (en) Spiropyrrolidine derivatives, their use and pharmaceutical compositions containing them
GB2327190B (en) Process for the preparation of depilatory compositions and their use
ZA973097B (en) Novel aspire-hydroxy acid derivatives their preparation and use
ZA981976B (en) Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation
IL117623A (en) Maltitol composition and its preparation
IL118443A0 (en) Cycloalkane-benzylidene derivatives their preparation and use
IL125149A (en) Pyrazol-4-yl-hetaroyl derivatives their preparation and herbicidal compositions comprising them
IL121691A0 (en) N-benzylazolium derivatives their preparation and compositions containing them
IL123092A0 (en) Pyrazol-4-ylbenzoyl derivatives their preparation and use
GR3035834T3 (en) Benzoxazindione derivatives, process for their preparation and their use