NO975977L - Substituted purine derivatives, processes for their preparation and use - Google Patents

Substituted purine derivatives, processes for their preparation and use

Info

Publication number
NO975977L
NO975977L NO975977A NO975977A NO975977L NO 975977 L NO975977 L NO 975977L NO 975977 A NO975977 A NO 975977A NO 975977 A NO975977 A NO 975977A NO 975977 L NO975977 L NO 975977L
Authority
NO
Norway
Prior art keywords
processes
preparation
purine derivatives
substituted purine
substituted
Prior art date
Application number
NO975977A
Other languages
Norwegian (no)
Other versions
NO975977D0 (en
NO314583B1 (en
Inventor
Anuschirwan Peyman
Jochen Knolle
Volkmar Wehner
Gerhard Breipohl
Jean-Fran Ois Gourvest
Denis Carniato
Thomas Richard Gadek
Original Assignee
Hoechst Ag
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag, Genentech Inc filed Critical Hoechst Ag
Publication of NO975977D0 publication Critical patent/NO975977D0/en
Publication of NO975977L publication Critical patent/NO975977L/en
Publication of NO314583B1 publication Critical patent/NO314583B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO19975977A 1996-12-20 1997-12-19 Substituted purine derivatives, methods of preparation and pharmaceutical compositions containing them NO314583B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19653646A DE19653646A1 (en) 1996-12-20 1996-12-20 Substituted purine derivatives, processes for their preparation, agents containing them and their use

Publications (3)

Publication Number Publication Date
NO975977D0 NO975977D0 (en) 1997-12-19
NO975977L true NO975977L (en) 1998-06-22
NO314583B1 NO314583B1 (en) 2003-04-14

Family

ID=7815761

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19975977A NO314583B1 (en) 1996-12-20 1997-12-19 Substituted purine derivatives, methods of preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
EP (1) EP0853084B1 (en)
JP (1) JP4620190B2 (en)
KR (1) KR19980064655A (en)
CN (2) CN1495184A (en)
AR (1) AR010700A1 (en)
AT (1) ATE404562T1 (en)
AU (1) AU728865B2 (en)
BR (1) BR9706387A (en)
CA (1) CA2225366C (en)
CZ (1) CZ294437B6 (en)
DE (2) DE19653646A1 (en)
HK (1) HK1012190A1 (en)
HU (1) HUP9702507A3 (en)
ID (1) ID19254A (en)
IL (1) IL122642A0 (en)
NO (1) NO314583B1 (en)
NZ (1) NZ329431A (en)
PL (1) PL323969A1 (en)
RU (1) RU2228335C2 (en)
TR (1) TR199701647A3 (en)
TW (1) TW523515B (en)
ZA (1) ZA9711317B (en)

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US6420558B1 (en) 1998-04-09 2002-07-16 Meiji Seika Kaisha, Ltd. Aminopiperidine derivates as integrin αvβ3 antagonists
JP2002533404A (en) 1998-12-23 2002-10-08 ジー・ディー・サール・アンド・カンパニー Methods of using integrin antagonists and radiation therapy as combination therapy in the treatment of neoplasia
UA71945C2 (en) 1999-01-27 2005-01-17 Pfizer Prod Inc Substituted bicyclic derivatives being used as anticancer agents
JP3270834B2 (en) 1999-01-27 2002-04-02 ファイザー・プロダクツ・インク Heteroaromatic bicyclic derivatives useful as anticancer agents
EP1065208A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Substituted purine derivatives as inhibitors of cell adhesion
EP1065207A1 (en) * 1999-07-02 2001-01-03 Aventis Pharma Deutschland GmbH Naphthyridine derivatives, processes for their preparation, their use, and pharmaceutical compositions comprising them
WO2001010844A1 (en) 1999-08-05 2001-02-15 Meiji Seika Kaisha, Ltd. φ-AMINO-α-HYDROXYCARBOXYLIC ACID DERIVATIVES HAVING INTEGRIN αvβ3 ANTAGONISM
EP1176145A1 (en) * 2000-07-28 2002-01-30 Aventis Pharma Deutschland GmbH Novel guanidino derivatives as inhibitors of cell adhesion
DE10042655A1 (en) 2000-08-31 2002-03-14 Aventis Pharma Gmbh Process for the preparation of inhibitors of cell adhesion
KR100438820B1 (en) * 2001-03-05 2004-07-05 삼성코닝 주식회사 Method for manufacturing compound semiconductor substrate of III-V group
CN1247258C (en) 2001-04-24 2006-03-29 默克专利有限公司 Combination therapy using anti-angiogenic agents and tnfa
FR2847254B1 (en) * 2002-11-19 2005-01-28 Aventis Pharma Sa NOVEL VITRONECTIN RECEPTOR ANTAGONIST DERIVATIVES, PROCESS FOR PREPARING THEM, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS REFLECTING THEM
FR2870541B1 (en) 2004-05-18 2006-07-14 Proskelia Sas ANTIGONISTIC PYRIMIDINE DERIVATIVES OF VITRONECTIN RECEPTOR
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
ES2521679T3 (en) 2006-01-18 2014-11-13 Merck Patent Gmbh Specific therapy using integrin ligands for cancer treatment
JP2010516645A (en) 2007-01-18 2010-05-20 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング Specific therapies and drugs using integrin ligands to treat cancer
ES2677246T3 (en) 2007-10-11 2018-07-31 Daiichi Sankyo Company, Limited Antibody that targets Siglec-15 osteoclast-related protein
NZ586129A (en) * 2007-11-14 2012-06-29 Myrexis Inc Therapeutic compounds and their use in treating diseases and disorders
JP5653909B2 (en) 2009-04-09 2015-01-14 第一三共株式会社 Anti-Siglec-15 antibody
KR20120104491A (en) 2009-05-25 2012-09-21 메르크 파텐트 게엠베하 Continuous administration of cilengitide in cancer treatments
MX2013003828A (en) 2010-10-05 2013-06-28 Daiichi Sankyo Co Ltd Antibody targeting osteoclast-related protein siglec-15.
SG11201405966PA (en) 2012-03-30 2014-11-27 Daiichi Sankyo Co Ltd Cdr-modified anti-siglec-15 antibody
CN103665043B (en) 2012-08-30 2017-11-10 江苏豪森药业集团有限公司 A kind of tenofovir prodrug and its application in medicine
JP6649902B2 (en) 2014-05-30 2020-02-19 ファイザー・インク Carbonitrile derivatives as selective androgen receptor modulators
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

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JPS4730696Y1 (en) * 1966-12-10 1972-09-13
JPS6396663A (en) * 1986-10-13 1988-04-27 Mita Ind Co Ltd Electrostatic charge image developing toner
JPS6396553A (en) * 1986-10-14 1988-04-27 Sekisui Chem Co Ltd Packing material
DE4129603A1 (en) * 1991-09-06 1993-03-11 Thomae Gmbh Dr K CONDENSED 5-LOW HETEROCYCLES, METHOD FOR THE PRODUCTION THEREOF, AND MEDICAMENTS CONTAINING THESE COMPOUNDS
MX9207334A (en) * 1991-12-18 1993-08-01 Glaxo Inc NUCLEIC ACIDS PEPTIDICS AND PHARMACEUTICAL FORMULATION CONTAINING THEM
FR2700337B1 (en) * 1993-01-11 1995-04-14 Lafon Labor Imidazopyridine-2-one derivatives, their preparation process and their use in therapy.
US6133444A (en) * 1993-12-22 2000-10-17 Perseptive Biosystems, Inc. Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions
DE4405378A1 (en) * 1994-02-19 1995-08-24 Merck Patent Gmbh Adhesion receptor antagonists
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US5929046A (en) * 1994-06-08 1999-07-27 Cancer Research Campaign Technology Limited Pyrimidine and purine derivatives and their use in treating tumour cells
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
BR9508178A (en) * 1994-06-29 1997-11-18 Smithkline Beecham Corp Vitronectin receptor antagonists
US5525606A (en) * 1994-08-01 1996-06-11 The United States Of America As Represented By The Department Of Health And Human Services Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
WO1996020212A2 (en) * 1994-12-28 1996-07-04 Buchardt, Dorte Peptide nucleic acid incorporating a chiral backbone
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
DE69632324T2 (en) * 1995-06-07 2005-06-16 PerSeptive Biosystems, Inc., Framingham PNA-DNA CHIMESES AND PNA SYNTHESES FOR THEIR PREPARATION
JPH1025294A (en) * 1996-03-26 1998-01-27 Akira Matsuda Condensed heterocyclic derivative, its production and malignant tumor therapeutic agent containing the same
JP2000507552A (en) * 1996-03-26 2000-06-20 デュポン ファーマシューティカルズ カンパニー Aryloxy and arylthio fused pyridines, aryloxy and arylthio fused pyrimidines and derivatives thereof
GB9613021D0 (en) * 1996-06-21 1996-08-28 Pharmacia Spa Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors
AU717387B2 (en) * 1996-07-24 2000-03-23 Rolf H. Berg Peptide nucleic acids having enhanced binding affinity, sequence specificity and solubility
US5866702A (en) * 1996-08-02 1999-02-02 Cv Therapeutics, Incorporation Purine inhibitors of cyclin dependent kinase 2

Also Published As

Publication number Publication date
EP0853084A3 (en) 1998-09-09
DE59712958D1 (en) 2008-09-25
PL323969A1 (en) 1998-06-22
TW523515B (en) 2003-03-11
HK1012190A1 (en) 1999-07-30
NZ329431A (en) 2000-01-28
CN1495184A (en) 2004-05-12
JPH10182645A (en) 1998-07-07
AR010700A1 (en) 2000-06-28
CA2225366C (en) 2006-10-10
EP0853084A2 (en) 1998-07-15
IL122642A0 (en) 1998-08-16
EP0853084B1 (en) 2008-08-13
JP4620190B2 (en) 2011-01-26
ATE404562T1 (en) 2008-08-15
MX9710277A (en) 1998-10-31
ID19254A (en) 1998-06-28
AU4846697A (en) 1998-06-25
AU728865B2 (en) 2001-01-18
CZ411497A3 (en) 1998-07-15
ZA9711317B (en) 1998-06-22
NO975977D0 (en) 1997-12-19
CA2225366A1 (en) 1998-06-20
HU9702507D0 (en) 1998-03-02
HUP9702507A3 (en) 1999-12-28
TR199701647A2 (en) 1998-07-21
RU2228335C2 (en) 2004-05-10
HUP9702507A2 (en) 1999-05-28
DE19653646A1 (en) 1998-06-25
TR199701647A3 (en) 1998-07-21
CZ294437B6 (en) 2005-01-12
CN1101816C (en) 2003-02-19
KR19980064655A (en) 1998-10-07
CN1193623A (en) 1998-09-23
BR9706387A (en) 2000-03-14
NO314583B1 (en) 2003-04-14

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