EA015606B1 - Способ лечения связанного с глюкозой расстройства - Google Patents

Способ лечения связанного с глюкозой расстройства Download PDF

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Publication number
EA015606B1
EA015606B1 EA200870088A EA200870088A EA015606B1 EA 015606 B1 EA015606 B1 EA 015606B1 EA 200870088 A EA200870088 A EA 200870088A EA 200870088 A EA200870088 A EA 200870088A EA 015606 B1 EA015606 B1 EA 015606B1
Authority
EA
Eurasian Patent Office
Prior art keywords
dihydrobenzo
compound
dioxinyl
group
acid
Prior art date
Application number
EA200870088A
Other languages
English (en)
Russian (ru)
Other versions
EA200870088A1 (ru
Inventor
Вирджиния Л. Смит-Свинтоски
Аллен Б. Рейтц
Original Assignee
Янссен Фармацевтика Н.В.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Янссен Фармацевтика Н.В. filed Critical Янссен Фармацевтика Н.В.
Publication of EA200870088A1 publication Critical patent/EA200870088A1/ru
Publication of EA015606B1 publication Critical patent/EA015606B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
EA200870088A 2005-12-19 2006-12-19 Способ лечения связанного с глюкозой расстройства EA015606B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75167705P 2005-12-19 2005-12-19
US11/611,961 US8497298B2 (en) 2005-12-19 2006-12-18 Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
PCT/US2006/048477 WO2007092086A2 (en) 2005-12-19 2006-12-19 Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels

Publications (2)

Publication Number Publication Date
EA200870088A1 EA200870088A1 (ru) 2009-02-27
EA015606B1 true EA015606B1 (ru) 2011-10-31

Family

ID=38225368

Family Applications (2)

Application Number Title Priority Date Filing Date
EA200870088A EA015606B1 (ru) 2005-12-19 2006-12-19 Способ лечения связанного с глюкозой расстройства
EA201000630A EA016892B1 (ru) 2005-12-19 2006-12-19 Применение бензоконденсированных гетероциклических сульфамидных производных для понижения уровней липидов в крови

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201000630A EA016892B1 (ru) 2005-12-19 2006-12-19 Применение бензоконденсированных гетероциклических сульфамидных производных для понижения уровней липидов в крови

Country Status (24)

Country Link
US (1) US8497298B2 (https=)
EP (1) EP1973541B1 (https=)
JP (1) JP5190374B2 (https=)
KR (1) KR101363332B1 (https=)
CN (1) CN101365441B (https=)
AT (1) ATE486595T1 (https=)
AU (1) AU2006337617B8 (https=)
BR (1) BRPI0620011A2 (https=)
CA (1) CA2634419C (https=)
CR (1) CR10169A (https=)
CY (1) CY1111161T1 (https=)
DE (1) DE602006018066D1 (https=)
DK (1) DK1973541T3 (https=)
EA (2) EA015606B1 (https=)
HR (1) HRP20110008T1 (https=)
IL (1) IL192101A (https=)
MY (1) MY148866A (https=)
NO (1) NO20083003L (https=)
NZ (1) NZ569043A (https=)
PL (1) PL1973541T3 (https=)
PT (1) PT1973541E (https=)
RS (1) RS51521B (https=)
SI (1) SI1973541T1 (https=)
WO (1) WO2007092086A2 (https=)

Families Citing this family (16)

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Publication number Priority date Publication date Assignee Title
MY147767A (en) 2004-06-16 2013-01-31 Janssen Pharmaceutica Nv Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders
KR20080012360A (ko) * 2005-05-20 2008-02-11 얀센 파마슈티카 엔.브이. 설파미드 유도체의 제조 방법
US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
EA200870556A1 (ru) 2006-05-19 2009-06-30 Янссен Фармацевтика Н.В. Комбинированная терапия в лечении эпилепсии и родственных расстройств
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
US20090247616A1 (en) * 2008-03-26 2009-10-01 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety
EA018567B1 (ru) 2008-06-23 2013-08-30 Янссен Фармацевтика Нв Кристаллическая форма (2s)-(-)-n-(6-хлор-2,3-дигидробензо[1,4]диоксин-2-илметил)сульфамида
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
JP2014528953A (ja) 2011-09-29 2014-10-30 ヤンセン ファーマシューティカ エヌ．ベー． スルファミド誘導体の調製プロセス
KR20140082762A (ko) 2011-09-29 2014-07-02 얀센 파마슈티카 엔.브이. 설파미드 유도체의 개선된 제조 방법
JP6227535B2 (ja) * 2012-08-30 2017-11-08 株式会社三和化学研究所 脂質異常症の予防又は治療薬
CN105232544A (zh) * 2015-11-11 2016-01-13 朱忠良 一种抗糖尿病的口服药物组合物
CN105232543A (zh) * 2015-11-11 2016-01-13 朱忠良 一种抗糖尿病的口服药物组合物

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WO2006007435A1 (en) * 2004-06-16 2006-01-19 Janssen Pharmaceutica, N.V. Sulfamate and sulfamide derivatives for the treatment of epilepsy and related disorders

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