|
JPS6058915A
(ja)
*
|
1983-09-12 |
1985-04-05 |
Fujisawa Pharmaceut Co Ltd |
薬物含有脂質小胞体製剤
|
|
JPS6072831A
(ja)
*
|
1983-09-29 |
1985-04-24 |
Kao Corp |
ベシクル用組成物
|
|
JPS6072830A
(ja)
*
|
1983-09-29 |
1985-04-24 |
Kao Corp |
ベシクル用組成物
|
|
EP0152379A3
(de)
*
|
1984-02-15 |
1986-10-29 |
Ciba-Geigy Ag |
Verfahren zur Herstellung von pharmazeutischen Zusammensetzungen enthaltend unilamellare Liposomen
|
|
DE3515335C2
(de)
*
|
1985-04-27 |
1995-01-26 |
Bayer Ag |
Arzneizubereitung enthaltend Dihydropyridine und Verfahren zu ihrer Herstellung
|
|
IL79114A
(en)
*
|
1985-08-07 |
1990-09-17 |
Allergan Pharma |
Method and composition for making liposomes
|
|
MY101125A
(en)
*
|
1985-12-23 |
1991-07-31 |
Kao Corp |
Gel-like emulsion and o/w emulsions obtained from gel-like emulsion
|
|
FR2597346B1
(fr)
*
|
1986-04-22 |
1989-08-18 |
Oreal |
Procede pour faciliter la formation de niosomes en dispersion dans une phase aqueuse et pour ameliorer leur stabilite et leur taux d'encapsulation, et dispersions correspondantes.
|
|
FR2597367B1
(fr)
*
|
1986-04-22 |
1988-07-15 |
Oreal |
Procede pour faciliter la formation de spherules lipidiques en dispersion dans une phase aqueuse et pour ameliorer leur stabilite et leur taux d'encapsulation, et dispersions correspondantes.
|
|
GB8630273D0
(en)
*
|
1986-12-18 |
1987-01-28 |
Til Medical Ltd |
Pharmaceutical delivery systems
|
|
DK86988A
(da)
*
|
1987-02-25 |
1988-08-26 |
Takeda Chemical Industries Ltd |
Liposompraeparat og anvendelse deraf
|
|
JP2611307B2
(ja)
*
|
1987-02-25 |
1997-05-21 |
武田薬品工業株式会社 |
リポソーム製剤およびその製造法
|
|
US5252336A
(en)
*
|
1990-04-18 |
1993-10-12 |
Takeda Chemical Industries, Ltd. |
Liposome composition whose liposome membrane contains a polyoxyethylene derivative
|
|
DE4107152C2
(de)
*
|
1991-03-06 |
1994-03-24 |
Gregor Cevc |
Präparate zur nichtinvasiven Verabreichung von Antidiabetica
|
|
US6165500A
(en)
*
|
1990-08-24 |
2000-12-26 |
Idea Ag |
Preparation for the application of agents in mini-droplets
|
|
CA2067754C
(en)
*
|
1990-08-24 |
2002-06-04 |
Gregor Cevc |
Preparation for the application of agents in mini-droplets
|
|
DE4107153A1
(de)
*
|
1991-03-06 |
1992-09-10 |
Gregor Cevc |
Praeparat zur wirkstoffapplikation in kleinsttroepfchenform
|
|
FR2674128A1
(fr)
*
|
1991-03-19 |
1992-09-25 |
Patrinove |
"vecteurs de structure capsulaire" et leurs applications dans le transport de substances ou principes actifs.
|
|
DE4208527A1
(de)
*
|
1992-03-17 |
1993-09-23 |
Max Planck Gesellschaft |
Liposomen mit negativer ueberschussladung
|
|
US5877016A
(en)
|
1994-03-18 |
1999-03-02 |
Genentech, Inc. |
Human trk receptors and neurotrophic factor inhibitors
|
|
US5708142A
(en)
|
1994-05-27 |
1998-01-13 |
Genentech, Inc. |
Tumor necrosis factor receptor-associated factors
|
|
DE4423131A1
(de)
*
|
1994-07-01 |
1996-01-04 |
Bayer Ag |
Neue hIL-4-Mutantenproteine als Antagonisten oder partielle Agonisten des humanen Interleukin 4
|
|
US6093697A
(en)
*
|
1994-11-07 |
2000-07-25 |
The University Of Virginia Patent Foundation |
Synthetic insulin mimetic substances
|
|
US7888466B2
(en)
|
1996-01-11 |
2011-02-15 |
Human Genome Sciences, Inc. |
Human G-protein chemokine receptor HSATU68
|
|
BR9612752A
(pt)
|
1996-10-25 |
2000-01-18 |
Human Genome Sciences Inc |
Neutrocina
|
|
US6156728A
(en)
|
1996-11-01 |
2000-12-05 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
US6593290B1
(en)
|
1996-11-01 |
2003-07-15 |
Genentech, Inc. |
Treatment of inner ear hair cells
|
|
CA2291221A1
(en)
|
1997-05-30 |
1998-12-03 |
Human Genome Sciences, Inc. |
32 human secreted proteins
|
|
US6663899B2
(en)
|
1997-06-13 |
2003-12-16 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
US6113947A
(en)
*
|
1997-06-13 |
2000-09-05 |
Genentech, Inc. |
Controlled release microencapsulated NGF formulation
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
US5906979A
(en)
*
|
1998-01-27 |
1999-05-25 |
Insmed Pharmaceuticals, Inc. |
Compositions and methods for treating metabolic diseases characterized by hyperandrogenism and/or anovulation and/or infertility
|
|
JP4485051B2
(ja)
|
1998-02-04 |
2010-06-16 |
ジェネンテック， インコーポレイテッド |
上皮細胞増殖因子としてのヘレグリンの用途
|
|
EP2050762A3
(en)
|
1998-03-10 |
2009-07-08 |
Genentech, Inc. |
Human cornichon-like protein and nucleic acids encoding it
|
|
JP4532733B2
(ja)
|
1998-03-17 |
2010-08-25 |
ジェネンテック， インコーポレイテッド |
Ｖｅｇｆおよびｂｍｐ１と相同なポリペプチド群
|
|
EP1093457B8
(en)
|
1998-03-19 |
2011-02-02 |
Human Genome Sciences, Inc. |
Cytokine receptor common gamma chain like
|
|
US6290987B1
(en)
*
|
1998-09-27 |
2001-09-18 |
Generex Pharmaceuticals, Inc. |
Mixed liposome pharmaceutical formulation with amphiphiles and phospholipids
|
|
AUPP785098A0
(en)
|
1998-12-21 |
1999-01-21 |
Victor Chang Cardiac Research Institute, The |
Treatment of heart disease
|
|
JP2002533379A
(ja)
|
1998-12-23 |
2002-10-08 |
イデア アクチェンゲゼルシャフト |
生体内における局所的に非侵襲性である用途のための改善された製剤
|
|
ES2173678T3
(es)
|
1999-01-27 |
2002-10-16 |
Idea Ag |
Vacunacion no invasiva a traves de la piel.
|
|
ES2173679T3
(es)
|
1999-01-27 |
2002-10-16 |
Idea Ag |
Inmunizacion/transporte transnasal con vehiculos altamente adaptables.
|
|
WO2000050620A2
(en)
|
1999-02-26 |
2000-08-31 |
Human Genome Sciences, Inc. |
Human endokine alpha and methods of use
|
|
US6635249B1
(en)
|
1999-04-23 |
2003-10-21 |
Cenes Pharmaceuticals, Inc. |
Methods for treating congestive heart failure
|
|
MXPA02000053A
(es)
|
1999-07-05 |
2003-07-21 |
Idea Ag |
Un metodo para mejorar el tratamiento a traves de barreras adaptables semipermeables.
|
|
AU2001266557A1
(en)
|
2000-04-12 |
2001-10-23 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
AU2001282856A1
(en)
|
2000-06-15 |
2001-12-24 |
Human Genome Sciences, Inc. |
Human tumor necrosis factor delta and epsilon
|
|
CA2648051A1
(en)
|
2000-06-23 |
2002-01-03 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
EP2792747A1
(en)
|
2000-06-23 |
2014-10-22 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of disorders involving angiogenesis
|
|
US6989247B2
(en)
|
2000-11-28 |
2006-01-24 |
Celltech R & D, Inc. |
Compositions and methods for diagnosing or treating psoriasis
|
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
|
AUPR546801A0
(en)
|
2001-06-05 |
2001-06-28 |
Commonwealth Scientific And Industrial Research Organisation |
Recombinant antibodies
|
|
AU2002335657A1
(en)
|
2001-08-24 |
2003-03-10 |
Neuronz Biosciences, Inc. |
Neural regeneration peptide and methods for their use in treatment of brain damage
|
|
KR101008785B1
(ko)
|
2001-08-29 |
2011-01-14 |
제넨테크, 인크. |
유사분열촉진 활성을 가진 Ｂｖ８ 핵산 및 폴리펩티드
|
|
MXPA04002751A
(es)
|
2001-09-24 |
2005-09-08 |
Univ Oregon Health & Science |
Modificacion del comportamiento de alimentacion.
|
|
US20030077282A1
(en)
|
2001-10-12 |
2003-04-24 |
Bigler Michael Eric |
Use of bispecific antibodies to regulate immune responses
|
|
EP2261250B1
(en)
|
2001-12-21 |
2015-07-01 |
Human Genome Sciences, Inc. |
GCSF-Albumin fusion proteins
|
|
AU2003201998C1
(en)
|
2002-01-10 |
2012-10-25 |
Imperial Innovations Limited |
Modification of feeding behavior
|
|
US8058233B2
(en)
|
2002-01-10 |
2011-11-15 |
Oregon Health And Science University |
Modification of feeding behavior using PYY and GLP-1
|
|
WO2003099320A1
(en)
|
2002-05-24 |
2003-12-04 |
Zensun (Shanghai) Sci-Tech.Ltd |
Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy
|
|
EP2305710A3
(en)
|
2002-06-03 |
2013-05-29 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
|
US7473432B2
(en)
|
2002-10-11 |
2009-01-06 |
Idea Ag |
NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery
|
|
ES2347239T3
(es)
|
2002-12-02 |
2010-10-27 |
Amgen Fremont Inc. |
Anticuerpos dirigidos al factor de necrosis tumoral y usos de los mismos.
|
|
GB0300571D0
(en)
|
2003-01-10 |
2003-02-12 |
Imp College Innovations Ltd |
Modification of feeding behaviour
|
|
NZ541480A
(en)
|
2003-03-12 |
2008-03-28 |
Genentech Inc |
Use of Bv8 and/or EG-VEGF to promote hematopoiesis
|
|
EP1613750B1
(en)
|
2003-03-19 |
2015-10-14 |
Amgen Fremont Inc. |
Antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen and uses thereof
|
|
WO2004103313A2
(en)
|
2003-05-20 |
2004-12-02 |
The American National Red Cross |
Methods of reducing vascular permeability in tissue by inhibition of tissue plasminogen activator (tpa) and tpa inhibitors useful therein
|
|
US7291590B2
(en)
|
2003-06-12 |
2007-11-06 |
Queen's University At Kingston |
Compositions and methods for treating atherosclerosis
|
|
CN104059147A
(zh)
|
2003-06-27 |
2014-09-24 |
艾默根佛蒙特有限公司 |
针对表皮生长因子受体的缺失突变体的抗体及其使用
|
|
EP1667521B1
(en)
|
2003-09-12 |
2011-12-07 |
Tercica, Inc. |
Methods for treatment of insulin-like growth factor-1 (igf-1) deficiency
|
|
WO2005074650A2
(en)
|
2004-02-02 |
2005-08-18 |
Ambrx, Inc. |
Modified human four helical bundle polypeptides and their uses
|
|
WO2005090564A1
(ja)
|
2004-03-19 |
2005-09-29 |
Genomidea Inc. |
血管内皮増殖促進遺伝子
|
|
US20050260679A1
(en)
|
2004-03-19 |
2005-11-24 |
Sirid-Aimee Kellerman |
Reducing the risk of human anti-human antibodies through V gene manipulation
|
|
EP1598428A1
(en)
|
2004-05-18 |
2005-11-23 |
Georg Dewald |
Methods and kits to detect Hereditary angioedema type III
|
|
AU2005265163B2
(en)
|
2004-06-18 |
2009-10-01 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
|
US8299083B2
(en)
|
2004-08-17 |
2012-10-30 |
The Johns Hopkins University |
PDE5 inhibitor compositions and methods for treating cardiac indications
|
|
CA2583061C
(en)
|
2004-10-06 |
2015-02-17 |
Kwang Guan Tay |
Antibody production method
|
|
EP1824886B1
(en)
|
2004-11-17 |
2010-12-22 |
Amgen Inc. |
Fully human monoclonal antibodies to il-13
|
|
ATE504602T1
(de)
|
2004-12-20 |
2011-04-15 |
Amgen Fremont Inc |
Für humane matriptase spezifische bindungsproteine
|
|
RU2394839C2
(ru)
|
2004-12-21 |
2010-07-20 |
Астразенека Аб |
Антитела против ангиопоэтина-2 и их применение
|
|
BRPI0519430A2
(pt)
|
2004-12-22 |
2009-02-10 |
Ambrx Inc |
hormânio do crescimento humano modificado
|
|
MX2007007590A
(es)
|
2004-12-22 |
2007-12-10 |
Ambrx Inc |
Composiciones que contienen, metodos que involucran y usos de aminoacidos no naturales y polipeptidos.
|
|
EP1851245B1
(en)
|
2005-01-26 |
2012-10-10 |
Amgen Fremont Inc. |
Antibodies against interleukin-1 beta
|
|
WO2007059082A1
(en)
|
2005-11-10 |
2007-05-24 |
Curagen Corporation |
Method of treating ovarian and renal cancer using antibodies against t cell immunoglobulin domain and mucin domain 1 (tim-1) antigen
|
|
PL2163562T3
(pl)
|
2005-06-21 |
2014-03-31 |
Xoma Us Llc |
Przeciwciała wiążące IL-1 beta i ich fragmenty
|
|
AU2006272497B2
(en)
|
2005-07-27 |
2012-07-19 |
University Of Florida Research Foundation, Inc. |
Small compounds that correct protein misfolding and uses thereof
|
|
EP3037544A1
(en)
|
2005-10-13 |
2016-06-29 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of systemic lupus erythematosus (sle) patients with autoantibody positive diseases
|
|
EP2339014B1
(en)
|
2005-11-16 |
2015-05-27 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
|
US20070213264A1
(en)
|
2005-12-02 |
2007-09-13 |
Mingdong Zhou |
Neuregulin variants and methods of screening and using thereof
|
|
WO2008024128A2
(en)
|
2005-12-05 |
2008-02-28 |
Simon Delagrave |
Loop-variant pdz domains as biotherapeutics, diagnostics and research reagents
|
|
CN105753983A
(zh)
|
2005-12-13 |
2016-07-13 |
阿斯利康(瑞典)有限公司 |
胰岛素样生长因子特异性结合蛋白及其用途
|
|
PL1969003T3
(pl)
|
2005-12-14 |
2011-05-31 |
Herantis Pharma Plc |
Zastosowanie białka czynnika neurotroficznego
|
|
CN101370519B
(zh)
|
2005-12-15 |
2013-07-24 |
阿斯利康(瑞典)有限公司 |
治疗癌症的促血管生成素-2拮抗剂和VEGF-A、KDR和/或Flt1拮抗剂的组合
|
|
BRPI0621124A2
(pt)
|
2005-12-22 |
2011-11-29 |
Genentech Inc |
métodos para recuperação de uma proteìna de ligação à heparina
|
|
RU2457854C2
(ru)
|
2005-12-30 |
2012-08-10 |
Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи Лимитед |
Длительное высвобождение нейрегулина для улучшения сердечной функции
|
|
TW200813091A
(en)
|
2006-04-10 |
2008-03-16 |
Amgen Fremont Inc |
Targeted binding agents directed to uPAR and uses thereof
|
|
JP5140824B2
(ja)
*
|
2006-04-19 |
2013-02-13 |
国立大学法人 東京大学 |
リゾホスファチジルスレオニンおよびその誘導体
|
|
WO2007143121A2
(en)
|
2006-06-01 |
2007-12-13 |
President And Fellows Of Harvard College |
Purification of a bivalently active antibody using a non-chromatographic method
|
|
CL2007002225A1
(es)
|
2006-08-03 |
2008-04-18 |
Astrazeneca Ab |
Agente de union especifico para un receptor del factor de crecimiento derivado de plaquetas (pdgfr-alfa); molecula de acido nucleico que lo codifica; vector y celula huesped que la comprenden; conjugado que comprende al agente; y uso del agente de un
|
|
EP2054437A2
(en)
|
2006-08-07 |
2009-05-06 |
Teva Biopharmaceuticals USA, Inc. |
Albumin-insulin fusion proteins
|
|
KR20090060294A
(ko)
|
2006-09-08 |
2009-06-11 |
암브룩스, 인코포레이티드 |
변형된 인간 혈장 폴리펩티드 또는 Ｆｃ 스캐폴드 및 그의 용도
|
|
AU2007319359A1
(en)
|
2006-11-14 |
2008-05-22 |
Genentech, Inc. |
Modulators of neuronal regeneration
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
CN103405768A
(zh)
|
2006-12-20 |
2013-11-27 |
爱克索马技术有限公司 |
用于治疗IL-1β相关疾病的方法
|
|
BRPI0809583B1
(pt)
|
2007-03-30 |
2022-02-22 |
Ambrx, Inc |
Polipeptídeo fgf-21 modificado, composição compreendendo o mesmo, método para produzir o referido polipetídeo fgf-21 e célula compreendendo um polinucleotídeo
|
|
WO2008140026A1
(ja)
|
2007-05-11 |
2008-11-20 |
Bizen Chemical Co., Ltd. |
新規のロイコトリエン受容体アンタゴニスト
|
|
US20110206673A1
(en)
|
2007-06-27 |
2011-08-25 |
Liu Dongxu |
Polypeptides and polynucleotides for artemin and related ligands, and methods of use thereof
|
|
US20090156488A1
(en)
|
2007-09-12 |
2009-06-18 |
Zensun (Shanghai) Science & Technology Limited |
Use of neuregulin for organ preservation
|
|
EP2040075A1
(en)
|
2007-09-24 |
2009-03-25 |
Julius-Maximilians-Universität Würzburg |
Compounds and markers for surface-enhanced raman scattering
|
|
EP2207809B1
(en)
|
2007-09-26 |
2013-07-03 |
U3 Pharma GmbH |
Heparin-binding epidermal growth factor-like growth factor antigen binding proteins
|
|
CN101918026B
(zh)
|
2007-11-20 |
2016-03-02 |
Ambrx公司 |
经修饰胰岛素多肽和其用途
|
|
US8637029B2
(en)
|
2007-12-20 |
2014-01-28 |
Xoma Technology Ltd. |
Methods for the treatment of gout
|
|
JP5702150B2
(ja)
|
2008-02-08 |
2015-04-15 |
アンブルックス, インコーポレイテッドAmbrx, Inc. |
修飾されているレプチンポリペプチドおよびそれらの使用
|
|
FI20080326A0
(fi)
|
2008-04-30 |
2008-04-30 |
Licentia Oy |
Neurotroofinen tekijä MANF ja sen käytöt
|
|
TR201904041T4
(tr)
|
2008-06-09 |
2019-04-22 |
Max Planck Gesellschaft |
Protein agregasyonu ile bağlantılı hastalıklarda ve/veya nörodejeneratif hastalıklarda rol oynayan proteinlerin agregasyonunu inhibe etmeye yönelik ilaçlar.
|
|
UA103774C2
(uk)
|
2008-07-23 |
2013-11-25 |
Амбркс, Інк. |
Модифіковані поліпептиди бичачого гранулоцитарного колонієстимулювального фактора (g-csf) та їх застосування
|
|
EP3629022A1
(en)
|
2008-07-25 |
2020-04-01 |
Richard W. Wagner |
Protein screening methods
|
|
CN104306967A
(zh)
|
2008-09-10 |
2015-01-28 |
霍夫曼-拉罗奇有限公司 |
抑制眼部血管生成的方法
|
|
US8192738B2
(en)
|
2008-09-19 |
2012-06-05 |
Medimmune, Llc |
Targeted antibodies directed to DLL4
|
|
CN107022020A
(zh)
|
2008-09-26 |
2017-08-08 |
Ambrx公司 |
修饰的动物促红细胞生成素多肽和其用途
|
|
MX343802B
(es)
|
2008-09-26 |
2016-11-23 |
Ambrx Inc |
Microorganismos y vacunas dependientes de replicacion de aminoacidos no naturales.
|
|
MX2011004306A
(es)
|
2008-10-22 |
2011-07-28 |
Genentech Inc |
Modulacion de degeneracion de axones.
|
|
WO2010070136A2
(en)
|
2008-12-19 |
2010-06-24 |
Centre de Recherche Public de la Santé |
Novel caviidae allergens and uses thereof
|
|
US20110312872A1
(en)
|
2008-12-22 |
2011-12-22 |
Universität Regensburg |
Norrin in the treatment of diseases associated with an increased tgf-beta activity
|
|
AU2009331528A1
(en)
|
2008-12-23 |
2011-08-11 |
Astrazeneca Ab |
Targeted binding agents directed to alpha5beta1 and uses thereof
|
|
EP2390261A4
(en)
|
2009-01-20 |
2012-11-14 |
Hanall Biopharma Co Ltd |
MODIFIED HUMAN THROMBOPOIETIN POLYPEPTIDE FRAGMENT AND METHOD FOR THE PRODUCTION THEREOF
|
|
WO2010093993A2
(en)
|
2009-02-12 |
2010-08-19 |
Human Genome Sciences, Inc. |
Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance
|
|
WO2010092109A2
(en)
|
2009-02-13 |
2010-08-19 |
Novartis Ag |
Nucleic acid molecule of a biosynthetic cluster encoding non ribosomal peptide synthases and uses thereof
|
|
EP2260857A1
(en)
|
2009-06-11 |
2010-12-15 |
Alfact Innovation |
Novel applications of HIP/PAP or derivatives thereof
|
|
IN2012DN00352A
(da)
|
2009-06-16 |
2015-08-21 |
Bikam Pharmaceuticals Inc |
|
|
EP2305285A1
(en)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Means and methods for treating ischemic conditions
|
|
EP2305810A1
(en)
|
2009-10-02 |
2011-04-06 |
Technische Universität München |
miRNAs in the treatment of fibrosis
|
|
WO2011046457A1
(en)
|
2009-10-16 |
2011-04-21 |
Auckland Uniservices Limited |
Anti-neoplastic uses of artemin antagonists
|
|
AU2010310589A1
(en)
|
2009-10-22 |
2012-05-10 |
Genentech, Inc. |
Modulation of axon degeneration
|
|
US8729058B2
(en)
|
2009-10-27 |
2014-05-20 |
Michael Zasloff |
Methods and compositions for treating and preventing viral infections
|
|
RS60033B1
(sr)
|
2009-11-24 |
2020-04-30 |
Medimmune Ltd |
Ciljano vezujući agensi usmereni na b7-h1
|
|
WO2011066260A2
(en)
|
2009-11-25 |
2011-06-03 |
Michael Zasloff |
Formulations comprising aminosterols
|
|
CN104017063A
(zh)
|
2009-12-21 |
2014-09-03 |
Ambrx公司 |
经过修饰的猪促生长素多肽和其用途
|
|
EA201290541A1
(ru)
|
2009-12-21 |
2013-05-30 |
Амбркс, Инк. |
Модифицированные бычьи соматотропиновые полипептиды и их применение
|
|
US20130053438A1
(en)
|
2010-01-19 |
2013-02-28 |
Universitat Innsbruck |
Pharmaceutical compositions comprising lignans and their derivatives for the medical management of angiogenesis and hypovascularity
|
|
CA2788021A1
(en)
|
2010-01-27 |
2011-08-04 |
Children's Medical Center Corporation |
Pro-angiogenic fragments of prominin-1 and uses thereof
|
|
WO2011131626A1
(en)
|
2010-04-19 |
2011-10-27 |
Medizinische Universität Innsbruck |
Tmem195 encodes for tetrahydrobiopterin-dependent alkylglycerol monooxygenase activity
|
|
EP2566964B1
(en)
|
2010-05-07 |
2016-10-19 |
Centre National De La Recherche Scientifique |
Ucp1 (thermogenin) - inducing agents for use in the treatment of a disorder of the energy homeostasis
|
|
CA2802635A1
(en)
|
2010-06-18 |
2011-12-22 |
Xiberscience Gmbh |
Peptides as active agents to stabilize biologic barriers
|
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
|
MA34521B1
(fr)
|
2010-08-17 |
2013-09-02 |
Ambrx Inc |
Polypeptides de relaxine modifiés et leurs utilisations
|
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
AU2012209466C1
(en)
|
2011-01-27 |
2016-06-23 |
Neuren Pharmaceuticals Limited |
Treatment of Autism Spectrum Disorders using Glycyl-L-2-Methylprolyl-L-Glutamic Acid
|
|
MX2013010185A
(es)
|
2011-03-10 |
2014-02-17 |
Genentech Inc |
Tratamiento de alteraciones con funcion de barrera vascular alterada.
|
|
CN103917093B
(zh)
|
2011-06-14 |
2017-08-11 |
比卡姆药品公司 |
视蛋白结合配体、组合物及使用方法
|
|
WO2013017656A1
(en)
|
2011-08-02 |
2013-02-07 |
Medizinische Universität Wien |
Antagonists of ribonucleases for treating obesity
|
|
WO2013025939A2
(en)
|
2011-08-16 |
2013-02-21 |
Indiana University Research And Technology Corporation |
Compounds and methods for treating cancer by inhibiting the urokinase receptor
|
|
WO2013024144A1
(en)
|
2011-08-16 |
2013-02-21 |
Evotec (München) Gmbh |
Markers for susceptibility to an inhibitor of an src-family kinase
|
|
WO2013053076A1
(en)
|
2011-10-10 |
2013-04-18 |
Zensun （Shanghai）Science & Technology Limited |
Compositions and methods for treating heart failure
|
|
MX2014005957A
(es)
|
2011-11-16 |
2015-02-04 |
Amgen Inc |
Metodos para tratar trastornos relacionados con mutante viii de eliminacion de factor de crecimiento epidermico.
|
|
AU2012346214B2
(en)
|
2011-11-30 |
2017-09-14 |
Bikam Pharmaceuticals, Inc. |
Opsin-binding ligands, compositions and methods of use
|
|
EP2601941A1
(en)
|
2011-12-06 |
2013-06-12 |
Ludwig-Maximilians-Universität München |
Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents
|
|
WO2013083810A1
(en)
|
2011-12-09 |
2013-06-13 |
F. Hoffmann-La Roche Ag |
Identification of non-responders to her2 inhibitors
|
|
CN104144946A
(zh)
|
2011-12-19 |
2014-11-12 |
爱克索马美国有限责任公司 |
治疗痤疮的方法
|
|
JP6684490B2
(ja)
|
2012-01-09 |
2020-04-22 |
ザ・スクリップス・リサーチ・インスティテュート |
超長相補性決定領域及びその使用
|
|
WO2013106489A1
(en)
|
2012-01-09 |
2013-07-18 |
The Scripps Research Institute |
Humanized antibodies with ultralong cdr3s
|
|
EP2626066A1
(en)
|
2012-02-10 |
2013-08-14 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Combination therapy comprising selective VEGFR-2 inhibitors and MEK inhibitors
|
|
EP2666775A1
(en)
|
2012-05-21 |
2013-11-27 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
JP6267193B2
(ja)
|
2012-05-22 |
2018-01-24 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
置換ジピリジルアミン類及びそれらの使用
|
|
EA026393B1
(ru)
|
2012-05-22 |
2017-04-28 |
Дженентек, Инк. |
N-замещенные бензамиды и их применение в лечении боли
|
|
EP2866821B1
(en)
|
2012-07-02 |
2018-11-14 |
Medizinische Universität Wien |
Complement split product c4d for the treatment of inflammatory conditions
|
|
KR101663436B1
(ko)
|
2012-07-06 |
2016-10-06 |
제넨테크, 인크. |
N-치환된 벤즈아미드 및 이의 사용 방법
|
|
EP2687225A1
(en)
|
2012-07-19 |
2014-01-22 |
Alfact Innovation |
HIP/PAP protein and derivatives thereof for use in treating cancer
|
|
EP2695950A1
(en)
|
2012-08-10 |
2014-02-12 |
Blackfield AG |
Markers for responsiveness to an inhibitor of the fibroblast growth factor receptor
|
|
WO2014031649A1
(en)
|
2012-08-21 |
2014-02-27 |
Genesys Research Institute |
Compositions and methods for treating or preventing anthracycline induced cardiotoxicity
|
|
MX2015003565A
(es)
|
2012-09-27 |
2015-06-22 |
Hoffmann La Roche |
Compuestos de sulfanamida sustituidos.
|
|
CN104813168B
(zh)
|
2012-11-30 |
2017-10-20 |
霍夫曼-拉罗奇有限公司 |
需要pd‑l1抑制剂综合疗法的患者的鉴定
|
|
CA2896187A1
(en)
|
2013-01-18 |
2014-07-24 |
F. Hoffmann-La Roche Ag |
3-substituted pyrazoles and use as dlk inhibitors
|
|
EP2968280A4
(en)
|
2013-03-14 |
2016-08-10 |
Genentech Inc |
SUBSTITUTED TRIAZOLOPYRIDINES AND METHOD OF USE THEREOF
|
|
MY182082A
(en)
|
2013-05-01 |
2021-01-18 |
Hoffmann La Roche |
Biheteroaryl compounds and uses thereof
|
|
CN105164114B
(zh)
|
2013-05-01 |
2018-03-23 |
豪夫迈·罗氏有限公司 |
C‑连接的杂环烷基取代的嘧啶类和它们的用途
|
|
EP2999797B1
(en)
|
2013-05-21 |
2018-07-04 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Isoforms of gata6 and nkx2-1 as markers for diagnosis and therapy of cancer and as targets for anti-cancer therapy
|
|
BR112015029293A2
(pt)
|
2013-05-22 |
2018-04-24 |
Zensun Shanghai Science & Tech Ltd |
método e kit para prevenir, tratar ou retardar uma doença ou distúrbio cardiovascular em um mamífero
|
|
WO2014191630A2
(en)
|
2013-05-28 |
2014-12-04 |
Helsingin Yliopisto |
Non-human animal model encoding a non-functional manf gene
|
|
US20160130585A1
(en)
|
2013-05-28 |
2016-05-12 |
The Johns Hopkins University |
Aptamers for the treatment of sickle cell disease
|
|
EP2810648A1
(en)
|
2013-06-04 |
2014-12-10 |
Daniel Rauh |
Targeting domain-domain interaction for the identification of kinase modulators
|
|
EP2835135A3
(en)
|
2013-06-19 |
2015-06-24 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
Means and methods for treating pseudomonas infection
|
|
WO2014207213A1
(en)
|
2013-06-28 |
2014-12-31 |
Medizinische Universität Innsbruck |
Novel inhibitors of protein kinase c epsilon signaling
|
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
|
CN111518199A
(zh)
|
2013-07-18 |
2020-08-11 |
图鲁斯生物科学有限责任公司 |
具有超长互补决定区的人源化抗体
|
|
WO2015022326A1
(en)
|
2013-08-12 |
2015-02-19 |
Xiber Science Gmbh |
Peptides as active agents for treating primary graft dysfunction
|
|
JP6822839B2
(ja)
|
2013-09-13 |
2021-01-27 |
ザ・スクリップス・リサーチ・インスティテュート |
修飾された治療剤、及びその組成物
|
|
JP6745220B2
(ja)
|
2013-09-16 |
2020-08-26 |
ツェーエムエム−フォルシュングスツェントルム フュア モレクラレ メディツィン ゲーエムベーハー |
骨髄性悪性腫瘍の診断のための突然変異体カルレチクリン
|
|
MX363457B
(es)
|
2013-10-11 |
2019-03-25 |
Hoffmann La Roche |
Compuestos de sulfonamida heterociclica sustituida utiles como moduladores del canal del receptor de potencial transitorio a1 (trpa1).
|
|
KR102339240B1
(ko)
|
2013-10-15 |
2021-12-15 |
더 스크립스 리서치 인스티튜트 |
펩타이드 키메라 항원 수용체 t 세포 스위치 및 이의 용도
|
|
ES2741308T3
(es)
|
2013-10-15 |
2020-02-10 |
Scripps Research Inst |
Interruptores de células T con receptores de antígenos quiméricos y usos de los mismos
|
|
EP4212180A1
(en)
|
2013-12-18 |
2023-07-19 |
The Scripps Research Institute |
Modified therapeutic agents, stapled peptide lipid conjugates, and compositions thereof
|
|
MX2016008110A
(es)
|
2013-12-20 |
2016-08-19 |
Hoffmann La Roche |
Derivados de pirazol como inhibidores de la cinasa de cremallera de leucina dual (dlk) y usos de los mismos.
|
|
EP3104873B1
(en)
|
2014-02-13 |
2019-09-04 |
Technische Universität München |
Fgf-8 for use in treating diseases or disorders of energy homeostasis
|
|
CN106458856A
(zh)
|
2014-03-07 |
2017-02-22 |
约翰霍普金斯大学 |
组蛋白赖氨酸特异性的脱甲基酶(lsd1)和组蛋白脱乙酰基酶(hdac)的抑制剂
|
|
US10507227B2
(en)
|
2014-04-15 |
2019-12-17 |
The Hospital For Sick Children |
Cationic antimicrobial peptides
|
|
US20170073690A1
(en)
|
2014-05-15 |
2017-03-16 |
CEMM - Forschungzentrum Fuer Molekulare Medizin GMBH |
Antagonists of slc38a9 and their use in therapy
|
|
EP2947460A1
(en)
|
2014-05-22 |
2015-11-25 |
Medizinische Universität Wien |
Personalized therapy of inflammation-associated cancer using methods of assessing the susceptibility of a subject to the treatment with EGFR inhibitors/antagonists
|
|
WO2015184260A2
(en)
|
2014-05-30 |
2015-12-03 |
The Johns Hopkins University |
Methods for treating mendelian disorders of the epigenetic machinery
|
|
US10005724B2
(en)
|
2014-07-07 |
2018-06-26 |
Genentech, Inc. |
Therapeutic compounds and methods of use thereof
|
|
JP6759203B2
(ja)
*
|
2014-08-09 |
2020-09-23 |
アバンティ・ポーラ・リピッド・インコーポレイテッド |
薬物及び他の物質の送達のための経口組成物
|
|
CA2958879A1
(en)
|
2014-08-22 |
2016-02-25 |
Auckland Uniservices Limited |
Channel modulators
|
|
EP3000814A1
(en)
|
2014-09-26 |
2016-03-30 |
Domain Therapeutics |
Substituted pyrazoloquinazolinones and pyrroloquinazolinones as allosteric modulators of group II metabotropic glutamate receptors
|
|
CN114805533A
(zh)
|
2014-10-24 |
2022-07-29 |
百时美施贵宝公司 |
修饰的fgf-21多肽及其用途
|
|
WO2016079321A1
(en)
|
2014-11-20 |
2016-05-26 |
Cemm Forschungszentrum Für Molekulare Medizin Gmbh |
Antagonists of setdb2 for use in the therapy of infectious diseases
|
|
WO2016135140A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
4-aminoquinazoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135137A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Substituted 4-(phenylamino)quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
WO2016135138A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxoquinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
RU2722832C2
(ru)
|
2015-02-23 |
2020-06-04 |
Сигалл Терапьютикс Сас |
Неприродные семафорины класса 3 и их медицинское применение
|
|
WO2016135139A1
(en)
|
2015-02-23 |
2016-09-01 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
2,3-dihydrocyclopenta[b]quinoline derivatives as mth1 inhibitors for the therapy of cancer
|
|
EP3268373B1
(en)
|
2015-03-09 |
2022-04-27 |
F. Hoffmann-La Roche AG |
Tricyclic dlk inhibitors and uses thereof
|
|
WO2016154621A1
(en)
|
2015-03-26 |
2016-09-29 |
The California Institute For Biomedical Research |
SWITCHABLE NON-scFv CHIMERIC RECEPTORS, SWITCHES, AND USES THEREOF
|
|
EP3283113A4
(en)
|
2015-04-15 |
2018-12-05 |
The California Institute for Biomedical Research |
Optimized pne-based chimeric receptor t cell switches and uses thereof
|
|
WO2016170102A1
(en)
|
2015-04-22 |
2016-10-27 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Combination of an antiandrogen with a vitamin k antagonist or with a gamma -glutamyl carboxylase inhibitor for the therapy of androgen receptor positive cancer
|
|
US20180146703A1
(en)
*
|
2015-05-15 |
2018-05-31 |
The Johns Hopkins University |
Novel fluoride prenatal dietary supplement
|
|
KR20180008761A
(ko)
|
2015-05-22 |
2018-01-24 |
제넨테크, 인크. |
치환된 벤즈아미드 및 이의 이용 방법
|
|
WO2016205488A1
(en)
|
2015-06-17 |
2016-12-22 |
The California Institute For Biomedical Research |
Modified therapeutic agents and compositions thereof
|
|
EP3319613B1
(en)
|
2015-07-07 |
2023-02-22 |
The Research Foundation for The State University of New York |
Use of amine carboxyboranes as therapeutic delivery of carbon monoxide and as general drug delivery system in the presence of reactive oxygen species
|
|
WO2017023793A2
(en)
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Methods for cancer and immunotherapy using glutamine analogues, including don
|
|
EP3328374A4
(en)
|
2015-07-31 |
2019-03-13 |
The Johns Hopkins University |
GLUTAMINANTAGONISTS FOR THE TREATMENT OF COGNITIVE DEFICITES
|
|
WO2017023774A1
(en)
|
2015-07-31 |
2017-02-09 |
The Johns Hopkins University |
Prodrugs of glutamine analogs
|
|
US10842763B2
(en)
|
2015-07-31 |
2020-11-24 |
The Johns Hopkins University |
Methods for cancer and immunotherapy using prodrugs of glutamine analogs
|
|
WO2017035271A1
(en)
|
2015-08-27 |
2017-03-02 |
Genentech, Inc. |
Therapeutic compounds and methods of use thereof
|
|
JP7100362B2
(ja)
|
2015-11-13 |
2022-07-13 |
ドメイン・セラピューティクス |
グループｉｉ代謝型グルタミン酸受容体のアロステリックモジュレーターとしての置換三環式１，４－ベンゾジアゼピノン誘導体
|
|
EP3380466A1
(en)
|
2015-11-25 |
2018-10-03 |
Genentech, Inc. |
Substituted benzamides useful as sodium channel blockers
|
|
SI3386997T1
(sl)
|
2015-12-09 |
2021-11-30 |
Medizinische Universitaet Wien |
Spojine platine s funkcionalnimi monomaleimidi za zdravljenje raka
|
|
KR20190031425A
(ko)
|
2016-01-15 |
2019-03-26 |
함부르크대학교 |
O-람노실 잔기를 보유하는 플라보노이드-유형 화합물
|
|
JP2019508496A
(ja)
|
2016-02-15 |
2019-03-28 |
チェム−フォルシュングスツェントルン フュル モレクラーレ メディツィン ゲゼルシャフト ミット ベシュレンクテル ハフツング |
癌の治療法のためのｔａｆ１阻害剤
|
|
EP3216458A1
(en)
|
2016-03-07 |
2017-09-13 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Modified vascular endothelial growth factor a (vegf-a) and its medical use
|
|
JP2019513714A
(ja)
|
2016-03-30 |
2019-05-30 |
ジェネンテック， インコーポレイテッド |
置換ベンズアミド及びその使用方法
|
|
GB2555264A
(en)
|
2016-04-15 |
2018-04-25 |
Univ Oxford Innovation Ltd |
Adenosine receptor modulators for the treatment of circadian rhythm disorders
|
|
WO2018005659A1
(en)
*
|
2016-06-28 |
2018-01-04 |
Aequor, Inc. |
Antimicrobial compounds and methods of use
|
|
WO2018015411A1
(en)
|
2016-07-20 |
2018-01-25 |
F. Hoffmann-La Roche Ag |
Sulfonylcycloalkyl carboxamide compounds as trpa1 modulators
|
|
EP3487853B1
(en)
|
2016-07-20 |
2022-06-08 |
F. Hoffmann-La Roche AG |
Bicyclic proline compounds
|
|
EP3493848B1
(en)
|
2016-08-02 |
2021-09-29 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Heterocyclic diamidines
|
|
WO2018029288A1
(en)
|
2016-08-12 |
2018-02-15 |
F. Hoffmann-La Roche Ag |
Sulfonyl pyridyl trp inhibitors
|
|
MX2019000735A
(es)
|
2016-09-16 |
2019-12-02 |
Res Triangle Inst |
Antagonistas opioides kappa de tetrahidroisoquinolina.
|
|
JP7349359B2
(ja)
|
2016-10-17 |
2023-09-22 |
エフ． ホフマン－ラ ロシュ アーゲー |
二環式ピリドンラクタム及びその使用方法。
|
|
KR20230172612A
(ko)
|
2016-10-19 |
2023-12-22 |
더 스크립스 리서치 인스티튜트 |
인간화된 표적화 모이어티 및/또는 최적화된 키메라 항원 수용체-상호작용 도메인을 갖는 키메라 항원 수용체 효과기 세포 스위치 및 이의 용도
|
|
AU2017359288A1
(en)
|
2016-11-14 |
2019-05-30 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Combination of a BRD4 inhibitor and an antifolate for the therapy of cancer
|
|
JP7171567B2
(ja)
|
2016-11-28 |
2022-11-15 |
エフ．ホフマン－ラ ロシュ アーゲー |
一過性受容体電位型チャネル阻害剤としてのオキサジアゾロン類
|
|
MA46937A
(fr)
|
2016-11-30 |
2019-10-09 |
Oncotyrol Center For Personalized Cancer Medicine Gmbh |
3-amino-1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-ones en tant qu'inhibiteurs de kinases dépendantes des cyclines
|
|
TW201831478A
(zh)
|
2016-12-02 |
2018-09-01 |
瑞士商赫孚孟拉羅股份公司 |
雙環醯胺化合物及其使用方法
|
|
US11072607B2
(en)
|
2016-12-16 |
2021-07-27 |
Genentech, Inc. |
Inhibitors of RIP1 kinase and methods of use thereof
|
|
TW201837051A
(zh)
|
2017-02-08 |
2018-10-16 |
美商必治妥美雅史谷比公司 |
包含藥物動力學增強劑之經修飾之鬆弛素(relaxin)多肽及其用途
|
|
WO2018162607A1
(en)
|
2017-03-07 |
2018-09-13 |
F. Hoffmann-La Roche Ag |
Oxadiazole transient receptor potential channel inhibitors
|
|
JP2020511511A
(ja)
|
2017-03-24 |
2020-04-16 |
ジェネンテック， インコーポレイテッド |
ナトリウムチャネル阻害剤としての４−ピペリジン−ｎ−（ピリミジン−４−イル）クロマン−７−スルホンアミド誘導体
|
|
CA3063288A1
(en)
|
2017-05-12 |
2018-11-15 |
Mavalon Therapeutics Limited |
Substituted heterocyclic compounds as allosteric modulators of group ii metabotropic glutamate receptors
|
|
AU2018265584B2
(en)
|
2017-05-12 |
2023-09-28 |
Ludwig-Maximilians-Universität München |
Phenyl-heterocycle-phenyl derivatives for use in the treatment or prevention of melanoma
|
|
PL3652178T3
(pl)
|
2017-07-14 |
2024-05-06 |
F. Hoffmann-La Roche Ag |
Bicykliczne związki ketonowe i sposoby ich stosowania
|
|
CA3070089A1
(en)
|
2017-07-19 |
2019-01-24 |
Auckland Uniservices Limited |
Cytokine modulation
|
|
KR20200070297A
(ko)
|
2017-10-11 |
2020-06-17 |
에프. 호프만-라 로슈 아게 |
Rip1 키나아제 억제제로서 사용하기 위한 이환형 화합물
|
|
WO2019089365A1
(en)
|
2017-10-30 |
2019-05-09 |
Enterin Laboratories, Inc. |
New squalamine solid forms and methods of making the same
|
|
WO2019086494A1
(en)
|
2017-10-31 |
2019-05-09 |
F. Hoffmann-La Roche Ag |
Bicyclic sulfones and sulfoxides and methods of use thereof
|
|
EP3720850A1
(en)
|
2017-12-05 |
2020-10-14 |
ETH Zurich |
New compounds for use as a therapeutically active substance and in particular for use in the treatment of tumors
|
|
AR114585A1
(es)
|
2018-02-20 |
2020-09-23 |
Hoffmann La Roche |
Proceso para preparar compuestos antagonistas de canales potenciales transitorios del receptor de 1-arilsulfonil-pirrolidin-2-carboxamida y formas cristalinas de los mismos
|
|
TW202000651A
(zh)
|
2018-02-26 |
2020-01-01 |
美商建南德克公司 |
治療性組成物及其使用方法
|
|
US10710994B2
(en)
|
2018-03-19 |
2020-07-14 |
Genentech, Inc. |
Oxadiazole transient receptor potential channel inhibitors
|
|
CN111936494A
(zh)
|
2018-03-30 |
2020-11-13 |
豪夫迈·罗氏有限公司 |
作为钠通道抑制剂的取代的氢-吡啶并-吖嗪
|
|
WO2019193161A1
(en)
|
2018-04-06 |
2019-10-10 |
Universität Wien |
Bumetanide derivatives for the therapy of stroke and other neurological diseases/disorders involving nkccs
|
|
AU2019247641A1
(en)
|
2018-04-06 |
2020-11-12 |
Zilentin AG |
Bumetanide derivatives for the therapy of hyperhidrosis
|
|
WO2019204537A1
(en)
|
2018-04-20 |
2019-10-24 |
Genentech, Inc. |
N-[4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-5,6-dihydro-4h-pyrrolo[1,2-b]pyrazol e-2-carboxamide derivatives and related compounds as rip1 kinase inhibitors for treating e.g. irritable bowel syndrome (ibs)
|
|
WO2019207051A1
(en)
|
2018-04-25 |
2019-10-31 |
Università Degli Studi Di Torino |
Medical use of combinations of non-natural semaphorins 3 and antimetabolites
|
|
TW202003490A
(zh)
|
2018-05-22 |
2020-01-16 |
瑞士商赫孚孟拉羅股份公司 |
治療性化合物及其使用方法
|
|
MX2021002301A
(es)
|
2018-08-28 |
2021-04-28 |
Ambrx Inc |
Bioconjugados de anticuerpo-foliato anti-cd3 y sus usos.
|
|
WO2020051099A1
(en)
|
2018-09-03 |
2020-03-12 |
Genentech, Inc. |
Carboxamide and sulfonamide derivatives useful as tead modulators
|
|
PT3849614T
(pt)
|
2018-09-11 |
2024-02-28 |
Ambrx Inc |
Conjugados de polipeptídeos de interleucina-2 e suas utilizações
|
|
WO2020053808A1
(en)
|
2018-09-12 |
2020-03-19 |
Georg Dewald |
Method of diagnosing vasoregulatory disorders
|
|
JP2022512746A
(ja)
|
2018-10-19 |
2022-02-07 |
アンブルックス，インコーポレイテッド |
インターロイキン－１０ポリペプチド複合体、その二量体、およびそれらの使用
|
|
US20230067929A1
(en)
|
2018-12-17 |
2023-03-02 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of cancer
|
|
WO2020146615A1
(en)
|
2019-01-11 |
2020-07-16 |
Genentech, Inc. |
Bicyclic pyrrolotriazolr ketone compounds and methods of use thereof
|
|
US20220226488A1
(en)
|
2019-02-12 |
2022-07-21 |
Ambrx, Inc. |
Compositions containing, methods and uses of antibody-tlr agonist conjugates
|
|
CA3148591A1
(en)
|
2019-07-26 |
2021-02-04 |
Amgen Inc. |
Anti-il13 antigen binding proteins
|
|
US20210047425A1
(en)
|
2019-08-12 |
2021-02-18 |
Purinomia Biotech, Inc. |
Methods and compositions for promoting and potentiating t-cell mediated immune responses through adcc targeting of cd39 expressing cells
|
|
WO2021064142A1
(en)
|
2019-10-02 |
2021-04-08 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer
|
|
WO2021064141A1
(en)
|
2019-10-02 |
2021-04-08 |
Tolremo Therapeutics Ag |
Inhibitors of dual specificity tyrosine phosphorylation regulated kinase 1b
|
|
US20230124700A1
(en)
|
2019-10-16 |
2023-04-20 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Oxazole and thioazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2021074418A1
(en)
|
2019-10-16 |
2021-04-22 |
Cemm - Forschungszentrum Für Molekulare Medizin Gmbh |
Carbazole-type cullin ring ubiquitin ligase compounds and uses thereof
|
|
AU2020371784A1
(en)
|
2019-10-24 |
2022-06-02 |
Minotaur Therapeutics, Inc. |
Chimeric cytokine modified antibodies and methods of use thereof
|
|
KR20220101138A
(ko)
|
2019-11-13 |
2022-07-19 |
제넨테크, 인크. |
치료적 화합물 및 사용 방법
|
|
JP2023502794A
(ja)
|
2019-11-19 |
2023-01-25 |
モダグ ゲーエムベーハー |
α－シヌクレインの凝集に関連する疾患の診断、治療および予防のための新規な化合物
|
|
WO2021173889A1
(en)
|
2020-02-26 |
2021-09-02 |
Ambrx, Inc. |
Uses of anti-cd3 antibody folate bioconjugates
|
|
JP2023517595A
(ja)
|
2020-03-11 |
2023-04-26 |
アンブルックス，インコーポレイテッド |
インターロイキン－２ポリペプチド結合物およびその使用方法
|
|
US20230235036A1
(en)
|
2020-06-05 |
2023-07-27 |
The J. David Gladstone Institutes, a testamentary trust established under the Will of J. David Glads |
Acvr1 (alk2) receptor inhibition to treat neurological diseases
|
|
GB202101299D0
(en)
|
2020-06-09 |
2021-03-17 |
Avacta Life Sciences Ltd |
Diagnostic polypetides and methods
|
|
WO2021260110A1
(en)
|
2020-06-25 |
2021-12-30 |
Tolremo Therapeutics Ag |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment, amelioration or prevention of fibrotic disease
|
|
EP3939578A1
(en)
|
2020-07-13 |
2022-01-19 |
Novaremed Ltd. |
Compounds for treatment or prevention of an infection resulting from a coronavirus and/or a coronavirus-induced disease
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
KR20230073200A
(ko)
|
2020-08-20 |
2023-05-25 |
암브룩스, 인코포레이티드 |
항체-tlr 작용제 접합체, 그 방법 및 용도
|
|
EP3964497A1
(en)
|
2020-09-04 |
2022-03-09 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Substituted vicinal diamine compounds and their use in the treatment, amelioration or prevention of pain
|
|
CA3200566A1
(en)
|
2020-10-02 |
2022-04-07 |
Genentech, Inc. |
Process for the preparation of biheteroaryl compounds and crystal forms thereof
|
|
CA3194868A1
(en)
|
2020-10-16 |
2022-04-21 |
Georg Winter |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|
|
WO2022087274A1
(en)
|
2020-10-21 |
2022-04-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Antibodies that neutralize type-i interferon (ifn) activity
|
|
CN117321076A
(zh)
|
2021-02-19 |
2023-12-29 |
美国卫生及公众服务部代表 |
中和SARS-CoV-2的单结构域抗体
|
|
JP2024512775A
(ja)
|
2021-04-03 |
2024-03-19 |
アンブルックス，インコーポレイテッド |
抗ｈｅｒ２抗体薬物コンジュゲート及びその使用
|
|
EP4320109A1
(en)
|
2021-04-07 |
2024-02-14 |
Tolremo Therapeutics AG |
Heterocyclic derivatives, pharmaceutical compositions and their use in the treatment or amelioration of cancer
|
|
EP4329887A1
(en)
|
2021-04-28 |
2024-03-06 |
Minotaur Therapeutics, Inc. |
Humanized chimeric bovine antibodies and methods of use
|
|
CN117677394A
(zh)
|
2021-05-14 |
2024-03-08 |
克拉里斯生物医疗股份有限公司 |
用于治疗眼部疾病的生长因子的组合物
|
|
WO2023028056A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
3-amino piperidyl sodium channel inhibitors
|
|
WO2023028077A1
(en)
|
2021-08-24 |
2023-03-02 |
Genentech, Inc. |
Sodium channel inhibitors and methods of designing same
|
|
US20230203062A1
(en)
|
2021-11-24 |
2023-06-29 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
TW202332429A
(zh)
|
2021-11-24 |
2023-08-16 |
美商建南德克公司 |
治療性化合物及其使用方法
|
|
US20230364031A1
(en)
|
2022-04-19 |
2023-11-16 |
Garth Cooper |
Treatment of brain copper disorders
|
|
WO2023203172A1
(en)
|
2022-04-20 |
2023-10-26 |
Proxygen Gmbh |
Heterocyclic cullin ring ubiquitin ligase compounds and uses thereof
|