DK3448382T3 - Arimoclomol til behandling af glucocerebrosidase-associerede lidelser - Google Patents

Arimoclomol til behandling af glucocerebrosidase-associerede lidelser Download PDF

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Publication number
DK3448382T3
DK3448382T3 DK17720480.7T DK17720480T DK3448382T3 DK 3448382 T3 DK3448382 T3 DK 3448382T3 DK 17720480 T DK17720480 T DK 17720480T DK 3448382 T3 DK3448382 T3 DK 3448382T3
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Denmark
Prior art keywords
arimoclomol
glucocerebrosidase
treatment
associated disorders
disorders
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DK17720480.7T
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English (en)
Inventor
Claus Bornaes
Cathrine Kolster Fog-Tønnesen
Anders Mørkeberg Hinsby
Thomas Kirkegaard Jensen
Nikolaj Havnsøe Torp Petersen
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Orphazyme As
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
DK17720480.7T 2016-04-29 2017-04-28 Arimoclomol til behandling af glucocerebrosidase-associerede lidelser DK3448382T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201670281 2016-04-29
PCT/EP2017/060205 WO2017186919A1 (en) 2016-04-29 2017-04-28 Arimoclomol for treating glucocerebrosidase associated disorders

Publications (1)

Publication Number Publication Date
DK3448382T3 true DK3448382T3 (da) 2020-12-07

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DK17720480.7T DK3448382T3 (da) 2016-04-29 2017-04-28 Arimoclomol til behandling af glucocerebrosidase-associerede lidelser

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US (3) US20190111041A1 (da)
EP (2) EP3782624A1 (da)
JP (2) JP6818045B2 (da)
KR (2) KR102254140B1 (da)
CN (1) CN109069496A (da)
AU (2) AU2017255959B2 (da)
BR (1) BR112018070653A2 (da)
CA (1) CA3021900A1 (da)
CY (1) CY1123717T1 (da)
DK (1) DK3448382T3 (da)
ES (1) ES2831764T3 (da)
HR (1) HRP20210047T1 (da)
HU (1) HUE052158T2 (da)
IL (2) IL262411B (da)
LT (1) LT3448382T (da)
PT (1) PT3448382T (da)
RS (1) RS61291B1 (da)
RU (2) RU2750154C2 (da)
SI (1) SI3448382T1 (da)
WO (1) WO2017186919A1 (da)

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Publication number Priority date Publication date Assignee Title
KR20230035586A (ko) * 2020-06-24 2023-03-14 켐팜 덴마크 에이/에스 고셔병을 치료하기 위한 아리모클로몰
IL303026A (en) 2020-11-19 2023-07-01 Zevra Denmark As Processes for preparing arimoclomol citrate and its intermediates

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US11253505B2 (en) 2022-02-22
WO2017186919A1 (en) 2017-11-02
RU2018138791A3 (da) 2020-06-25
JP6818045B2 (ja) 2021-01-20
CN109069496A (zh) 2018-12-21
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US20190111041A1 (en) 2019-04-18
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US20200289497A1 (en) 2020-09-17
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KR102254140B1 (ko) 2021-05-24
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