HU0103939D0 - Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride - Google Patents
Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chlorideInfo
- Publication number
- HU0103939D0 HU0103939D0 HU0103939A HUP0103939A HU0103939D0 HU 0103939 D0 HU0103939 D0 HU 0103939D0 HU 0103939 A HU0103939 A HU 0103939A HU P0103939 A HUP0103939 A HU P0103939A HU 0103939 D0 HU0103939 D0 HU 0103939D0
- Authority
- HU
- Hungary
- Prior art keywords
- methformin
- piperidinyl
- propoxy
- pyridine
- hydroxy
- Prior art date
Links
- SGEIEGAXKLMUIZ-PEZBUJJGSA-N (3z)-n-(2-hydroxy-3-piperidin-1-ylpropoxy)-1-oxidopyridin-1-ium-3-carboximidoyl chloride Chemical compound C1CCCCN1CC(O)CO\N=C(/Cl)C1=CC=C[N+]([O-])=C1 SGEIEGAXKLMUIZ-PEZBUJJGSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0103939A HU0103939D0 (en) | 2001-09-27 | 2001-09-27 | Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride |
PCT/HU2002/000098 WO2003026653A1 (en) | 2001-09-27 | 2002-09-26 | Pharmaceutical composition comprising metformin and n-`2-hydroxy-3-(1-piperidinyl)-propoxy! pyridine-1-oxide-3-carboximidoyl chloride |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0103939A HU0103939D0 (en) | 2001-09-27 | 2001-09-27 | Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride |
Publications (1)
Publication Number | Publication Date |
---|---|
HU0103939D0 true HU0103939D0 (en) | 2001-11-28 |
Family
ID=89979729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0103939A HU0103939D0 (en) | 2001-09-27 | 2001-09-27 | Pharmaceutical composition containing methformin and n-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride |
Country Status (2)
Country | Link |
---|---|
HU (1) | HU0103939D0 (en) |
WO (1) | WO2003026653A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0303584A3 (en) * | 2003-10-30 | 2009-12-28 | Cytrx Corp | Use of a hydroximic acid halide derivative in the treatment of neurodegenerative diseases |
JPWO2005117855A1 (en) * | 2004-06-04 | 2008-04-03 | 興和株式会社 | Drugs for the prevention or treatment of diabetes |
US20080227813A1 (en) * | 2006-09-26 | 2008-09-18 | Jack Raymond Barber | Pharmaceutical compositions and methods for treating diseases associated with neurodegeneration |
TW200901958A (en) * | 2007-05-04 | 2009-01-16 | Cytrx Corp | Diabetic wound healing |
CA2728363C (en) | 2008-06-26 | 2019-02-19 | Orphazyme Aps | Use of hsp70 as a regulator of enzymatic activity |
ES2753169T3 (en) | 2010-11-30 | 2020-04-07 | Orphazyme As | Procedures to increase intracellular activity of Hsp70 |
HUE054957T2 (en) * | 2014-09-15 | 2021-10-28 | Orphazyme As | Arimoclomol formulation |
WO2017178029A1 (en) | 2016-04-13 | 2017-10-19 | Orphazyme Aps | Heat shock proteins and cholesterol homeostasis |
ES2831764T3 (en) | 2016-04-29 | 2021-06-09 | Orphazyme As | Arimoclomol for the treatment of glucocerebrosidase-associated disorders |
WO2022106614A1 (en) | 2020-11-19 | 2022-05-27 | Orphazyme A/S | Processes for preparing arimoclomol citrate and intermediates thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP9900475D0 (en) * | 1999-02-26 | 1999-04-28 | Biorex Kutato Fejlesztoe Kft | O-(3-piperidino-2-hydroxy-1-propyl)-hiyroximic acid-halogenid derivative, it's use for treating insulin resistance, and pharmaceutical compositions containing them as active component |
HUP0001583A2 (en) * | 2000-04-18 | 2002-11-28 | BIOREX Kutató és Fejlesztő Rt. | A pyridine-1-oxide derivative and process for its transformation into pharmaceutically effective compounds |
-
2001
- 2001-09-27 HU HU0103939A patent/HU0103939D0/en unknown
-
2002
- 2002-09-26 WO PCT/HU2002/000098 patent/WO2003026653A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2003026653A1 (en) | 2003-04-03 |
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