AU2017255959B2 - Arimoclomol for treating glucocerebrosidase associated disorders - Google Patents

Arimoclomol for treating glucocerebrosidase associated disorders Download PDF

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AU2017255959B2
AU2017255959B2 AU2017255959A AU2017255959A AU2017255959B2 AU 2017255959 B2 AU2017255959 B2 AU 2017255959B2 AU 2017255959 A AU2017255959 A AU 2017255959A AU 2017255959 A AU2017255959 A AU 2017255959A AU 2017255959 B2 AU2017255959 B2 AU 2017255959B2
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gba
pharmaceutical ingredient
active pharmaceutical
use according
disease
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AU2017255959A1 (en
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Claus Bornaes
Cathrine Kolster Fog-Tonnesen
Anders Mørkeberg HINSBY
Thomas Kirkegaard Jensen
Nikolaj Havnsøe Torp Petersen
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Zevra Denmark AS
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Zevra Denmark AS
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
AU2017255959A 2016-04-29 2017-04-28 Arimoclomol for treating glucocerebrosidase associated disorders Active AU2017255959B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2020277270A AU2020277270B2 (en) 2016-04-29 2020-11-27 Arimoclomol for treating glucocerebrosidase associated disorders

Applications Claiming Priority (3)

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DKPA201670281 2016-04-29
DKPA201670281 2016-04-29
PCT/EP2017/060205 WO2017186919A1 (en) 2016-04-29 2017-04-28 Arimoclomol for treating glucocerebrosidase associated disorders

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AU2017255959A1 AU2017255959A1 (en) 2018-11-15
AU2017255959B2 true AU2017255959B2 (en) 2020-10-15

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US (3) US20190111041A1 (da)
EP (2) EP3448382B1 (da)
JP (2) JP6818045B2 (da)
KR (2) KR102254140B1 (da)
CN (1) CN109069496A (da)
AU (2) AU2017255959B2 (da)
BR (1) BR112018070653A2 (da)
CA (1) CA3021900A1 (da)
CY (1) CY1123717T1 (da)
DK (1) DK3448382T3 (da)
ES (1) ES2831764T3 (da)
HR (1) HRP20210047T1 (da)
HU (1) HUE052158T2 (da)
IL (2) IL262411B (da)
LT (1) LT3448382T (da)
PT (1) PT3448382T (da)
RS (1) RS61291B1 (da)
RU (2) RU2750154C2 (da)
SI (1) SI3448382T1 (da)
WO (1) WO2017186919A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3183559A1 (en) * 2020-06-24 2021-12-30 Thomas Kirkegaard Jensen Arimoclomol for treating gaucher disease
US20230416224A1 (en) 2020-11-19 2023-12-28 Zevra Denmark A/S Processes for preparing arimoclomol citrate and intermediates thereof

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