DK3290530T3 - Konservering af cellefrie nukleinsyrer - Google Patents
Konservering af cellefrie nukleinsyrer Download PDFInfo
- Publication number
- DK3290530T3 DK3290530T3 DK17185367.4T DK17185367T DK3290530T3 DK 3290530 T3 DK3290530 T3 DK 3290530T3 DK 17185367 T DK17185367 T DK 17185367T DK 3290530 T3 DK3290530 T3 DK 3290530T3
- Authority
- DK
- Denmark
- Prior art keywords
- preservation
- cell
- nucleic acids
- free nucleic
- free
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
- C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
- C09K15/20—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing nitrogen and oxygen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/125—Specific component of sample, medium or buffer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2527/00—Reactions demanding special reaction conditions
- C12Q2527/127—Reactions demanding special reaction conditions the enzyme inhibitor or activator used
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Materials Engineering (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15347209P | 2009-02-18 | 2009-02-18 | |
| EP10704474.5A EP2398912B1 (en) | 2009-02-18 | 2010-02-11 | Preservation of cell-free nucleic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3290530T3 true DK3290530T3 (da) | 2020-12-07 |
Family
ID=42112198
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK17185367.4T DK3290530T3 (da) | 2009-02-18 | 2010-02-11 | Konservering af cellefrie nukleinsyrer |
| DK10704474.5T DK2398912T3 (en) | 2009-02-18 | 2010-02-11 | Conservation of cell-free nucleic acids |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK10704474.5T DK2398912T3 (en) | 2009-02-18 | 2010-02-11 | Conservation of cell-free nucleic acids |
Country Status (7)
| Country | Link |
|---|---|
| US (10) | US8304187B2 (enExample) |
| EP (3) | EP3290530B1 (enExample) |
| DE (1) | DE202010018569U1 (enExample) |
| DK (2) | DK3290530T3 (enExample) |
| ES (1) | ES2649572T3 (enExample) |
| NO (1) | NO2398912T3 (enExample) |
| WO (1) | WO2010096323A1 (enExample) |
Families Citing this family (121)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10966421B2 (en) | 2002-10-16 | 2021-04-06 | Streck, Inc. | Method and device for collecting and preserving cells for analysis |
| US8532930B2 (en) | 2005-11-26 | 2013-09-10 | Natera, Inc. | Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals |
| US10081839B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US10083273B2 (en) | 2005-07-29 | 2018-09-25 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| CA3116156C (en) | 2008-08-04 | 2023-08-08 | Natera, Inc. | Methods for allele calling and ploidy calling |
| WO2010078194A1 (en) * | 2008-12-30 | 2010-07-08 | Streck, Inc. | Method for screening blood using a preservative that may be in a substantially solid state form |
| US11634747B2 (en) * | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| DE202010018569U1 (de) | 2009-02-18 | 2017-09-26 | Streck Inc. | Konservierung zellfreier Nukleinsäuren |
| WO2011041485A1 (en) | 2009-09-30 | 2011-04-07 | Gene Security Network, Inc. | Methods for non-invasive prenatal ploidy calling |
| EP3103883A1 (en) * | 2009-11-09 | 2016-12-14 | Streck, Inc. | Stabilization of rna in and extracting from intact cells within a blood sample |
| WO2011113043A2 (en) * | 2010-03-12 | 2011-09-15 | University Of South Florida | Sample storage for molecular and immunological detection |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| EP2854057B1 (en) | 2010-05-18 | 2018-03-07 | Natera, Inc. | Methods for non-invasive pre-natal ploidy calling |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| WO2012040603A2 (en) | 2010-09-23 | 2012-03-29 | Biocept, Inc. | Use of diazolidinyl urea for anti-clumping of biological samples |
| CA2821906C (en) | 2010-12-22 | 2020-08-25 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| JP6153874B2 (ja) | 2011-02-09 | 2017-06-28 | ナテラ, インコーポレイテッド | 非侵襲的出生前倍数性呼び出しのための方法 |
| US9956281B2 (en) | 2011-05-04 | 2018-05-01 | Streck, Inc. | Inactivated virus compositions and methods of preparing such compositions |
| EP2721140B1 (en) | 2011-06-19 | 2016-11-23 | Abogen, Inc. | Devices, solutions and methods for sample collection |
| ES2687126T3 (es) * | 2011-09-26 | 2018-10-23 | Qiagen Gmbh | Estabilización y aislamiento de ácidos nucleicos extracelulares |
| US11021733B2 (en) | 2011-09-26 | 2021-06-01 | Qiagen Gmbh | Stabilization and isolation of extracellular nucleic acids |
| CA2849354C (en) * | 2011-09-26 | 2021-11-09 | Preanalytix Gmbh | Stabilisation and isolation of extracellular nucleic acids |
| EP4159857A1 (en) | 2011-09-26 | 2023-04-05 | QIAGEN GmbH | Rapid method for isolating extracellular nucleic acids |
| WO2013074927A1 (en) * | 2011-11-16 | 2013-05-23 | University Of Georgia Research Foundation, Inc. | Method for isolating total rna from cells |
| EP3789499B1 (en) * | 2012-02-13 | 2023-03-15 | Streck, Inc. | Blood collection device for improved nucleic acid regulation |
| DE102012101896A1 (de) * | 2012-03-06 | 2013-09-12 | Roberto Gerigk | Formalinfreie Fixierungsmittel für histologische Färbungen von Gewebeproben |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| EP2888354B1 (en) * | 2012-08-21 | 2020-04-01 | Qiagen GmbH | Virus particle stabilisation and method for isolating viral nucleic acids |
| AU2013322643C1 (en) | 2012-09-25 | 2018-11-08 | Qiagen Gmbh | Stabilisation of biological samples |
| CA2839051A1 (en) | 2013-01-14 | 2014-07-14 | Streck, Inc. | Blood collection device for stabilizing cell-free rna in blood during sample shipping and storage |
| CA2906818C (en) | 2013-03-15 | 2022-08-16 | Verinata Health, Inc. | Generating cell-free dna libraries directly from blood |
| EP2976424B1 (en) * | 2013-03-18 | 2018-10-03 | Qiagen GmbH | Stabilisation of biological samples |
| WO2014146782A1 (en) | 2013-03-18 | 2014-09-25 | Qiagen Gmbh | Stabilization and isolation of extracellular nucleic acids |
| WO2015013244A1 (en) | 2013-07-24 | 2015-01-29 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
| US9644232B2 (en) | 2013-07-26 | 2017-05-09 | General Electric Company | Method and device for collection and amplification of circulating nucleic acids |
| US10577655B2 (en) | 2013-09-27 | 2020-03-03 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US10262755B2 (en) | 2014-04-21 | 2019-04-16 | Natera, Inc. | Detecting cancer mutations and aneuploidy in chromosomal segments |
| US9499870B2 (en) | 2013-09-27 | 2016-11-22 | Natera, Inc. | Cell free DNA diagnostic testing standards |
| US20170009288A1 (en) | 2014-02-03 | 2017-01-12 | Thermo Fisher Scientific Baltics Uab | Method for controlled dna fragmentation |
| EP3119197A1 (en) | 2014-03-18 | 2017-01-25 | Qiagen GmbH | Stabilization and isolation of extracellular nucleic acids |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| AU2015249846B2 (en) | 2014-04-21 | 2021-07-22 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US20170198335A1 (en) * | 2014-06-10 | 2017-07-13 | Biomatrica, Inc. | Stabilization of Non-Denatured Polypeptides, Nucleic Acids, and Exosomes in a Blood Sample at Ambient Temperatures |
| EP3942931A1 (en) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilization of thrombocytes at ambient temperatures |
| WO2016004308A1 (en) * | 2014-07-02 | 2016-01-07 | Siemens Healthcare Diagnostics Inc. | Selective nucleic acid separation |
| US10119167B2 (en) | 2014-07-18 | 2018-11-06 | Illumina, Inc. | Non-invasive prenatal diagnosis of fetal genetic condition using cellular DNA and cell free DNA |
| KR20170083563A (ko) | 2014-11-14 | 2017-07-18 | 리퀴드 제노믹스, 아이엔씨. | 암 진단 및/또는 모니터링을 위한 무세포 rna의 사용 방법 |
| US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
| EP3294906B1 (en) | 2015-05-11 | 2024-07-10 | Natera, Inc. | Methods for determining ploidy |
| EP3307886B1 (en) | 2015-06-10 | 2021-03-24 | Qiagen GmbH | Method for isolating extracellular nucleic acids using anion exchange particles |
| FI4035762T3 (fi) | 2015-09-09 | 2023-12-04 | Drawbridge Health Inc | Laitteita näytteiden keräämistä, stabilointia ja säilytystä varten |
| US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
| EP3377645B1 (en) | 2015-11-20 | 2023-10-04 | Qiagen GmbH | Method of preparing sterilized compositions for stabilization of extracellular nucleic acids |
| EP4242628B1 (en) | 2015-12-08 | 2025-07-02 | Biomatrica, Inc. | Reduction of erythrocyte sedimentation rate |
| DE102016102346A1 (de) * | 2016-02-10 | 2017-08-10 | Biosepar Gesellschaft für Medizin- und Labortechnik mbH | Fixativum |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| EP3464588B2 (en) | 2016-05-27 | 2025-01-08 | Norgen Biotek Corporation | Preservation of cell-free nucleic acids in biological samples |
| EP3491381B1 (en) | 2016-07-29 | 2025-09-24 | Streck LLC | Suspension composition for hematology analysis control |
| EP3845665A1 (en) | 2016-08-17 | 2021-07-07 | The Regents Of The University Of California | A novel immunoprobe-based method to assess organ injury status through a biofluid-based cell-free dna (cfdna) assay |
| WO2018067517A1 (en) | 2016-10-04 | 2018-04-12 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| US20210072255A1 (en) | 2016-12-16 | 2021-03-11 | The Brigham And Women's Hospital, Inc. | System and method for protein corona sensor array for early detection of diseases |
| EP3585889A1 (en) | 2017-02-21 | 2020-01-01 | Natera, Inc. | Compositions, methods, and kits for isolating nucleic acids |
| US11795192B2 (en) | 2017-03-10 | 2023-10-24 | Lakewood Amedex, Inc. | Antimicrobial compounds, compositions, and uses thereof |
| CN110431238A (zh) * | 2017-03-17 | 2019-11-08 | 南托米克斯有限责任公司 | cfRNA的液体活检 |
| EP3625357A4 (en) * | 2017-05-16 | 2021-02-24 | The Chinese University Of Hong Kong | INTEGRATIVE ANALYSIS OF ACELLULAR AND MONOCELLULAR PLASMA RNA |
| EP3631006A4 (en) | 2017-06-01 | 2020-06-03 | Nantomics, LLC | DNA STABILIZATION OF RNA |
| CN110997933B (zh) * | 2017-08-02 | 2024-01-09 | 萨斯特德特股份有限两合公司 | 用于稳定无细胞核酸和细胞的方法和组合物 |
| CA3079415A1 (en) * | 2017-10-19 | 2019-04-25 | Streck, Inc. | Compositions for hemolysis and coagulation regulation and stabilization of extracellular vesicles |
| WO2019094363A2 (en) * | 2017-11-07 | 2019-05-16 | Nanthealth Labs, Inc. | Targeted cell free nucleic acid analysis |
| WO2019118926A1 (en) | 2017-12-14 | 2019-06-20 | Tai Diagnostics, Inc. | Assessing graft suitability for transplantation |
| CN108048529B (zh) * | 2017-12-28 | 2021-01-19 | 广州市金圻睿生物科技有限责任公司 | 一种可稳定保存的肺癌甲基化基因检测试剂盒的质控品及应用 |
| CN108085391B (zh) * | 2017-12-28 | 2021-01-19 | 广州市金圻睿生物科技有限责任公司 | 一种可稳定保存的肺癌融合基因检测试剂盒的rna质控品 |
| CN108220478B (zh) * | 2017-12-28 | 2021-08-17 | 广州市金圻睿生物科技有限责任公司 | 可稳定保存的丙型肝炎病毒基因检测试剂盒的病毒质控品 |
| CN108103054B (zh) * | 2017-12-28 | 2020-10-02 | 广州市金圻睿生物科技有限责任公司 | 一种rna保存液及其用途 |
| CN108220417B (zh) * | 2017-12-28 | 2021-08-13 | 广州市金圻睿生物科技有限责任公司 | 可稳定保存的染色体非整倍体检测试剂盒的质控品及应用 |
| WO2019161244A1 (en) | 2018-02-15 | 2019-08-22 | Natera, Inc. | Methods for isolating nucleic acids with size selection |
| CA3090426A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| WO2019210306A1 (en) * | 2018-04-27 | 2019-10-31 | Momenta Pharmaceuticals , Inc. | Blood preparation |
| CN108893524A (zh) * | 2018-06-04 | 2018-11-27 | 北京启衡星生物科技有限公司 | 血浆中游离dna的保护剂 |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| EP3830296A1 (en) | 2018-07-27 | 2021-06-09 | F. Hoffmann-La Roche AG | Method of monitoring effectiveness of immunotherapy of cancer patients |
| EP3847653A2 (en) | 2018-09-07 | 2021-07-14 | Illumina, Inc. | A method to determine if a circulating fetal cell isolated from a pregnant mother is from either the current or a historical pregnancy |
| GB2595583A (en) | 2018-11-07 | 2021-12-01 | Seer Inc | Compositions, methods and systems for protein corona analysis and uses thereof |
| WO2020140035A1 (en) | 2018-12-27 | 2020-07-02 | Streck, Inc. | Methods of preparing samples for proteomic analysis |
| CN111378708B (zh) * | 2018-12-28 | 2022-07-19 | 康码(上海)生物科技有限公司 | 一种体外无细胞蛋白合成体系及其应用 |
| CN114206214A (zh) | 2019-03-26 | 2022-03-18 | 禧尔公司 | 用于生物流体的蛋白质冕分析的组合物、方法和系统及其用途 |
| EP3980559A1 (en) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| CN110747193B (zh) * | 2019-09-25 | 2021-08-31 | 广州市达瑞生物技术股份有限公司 | 一种基于二代测序平台的肺癌多基因联合检测试剂盒质控品 |
| CN111117999A (zh) * | 2019-12-18 | 2020-05-08 | 上海兰卫医学检验所股份有限公司 | 一种适用于液态活检技术的血浆exRNA提取保存方法 |
| WO2021173722A2 (en) * | 2020-02-24 | 2021-09-02 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of analyzing cell free nucleic acids and applications thereof |
| EP4176268A1 (en) | 2020-07-01 | 2023-05-10 | Streck LLC | Methods of preparing samples for proteomic analysis |
| JP2023533323A (ja) * | 2020-07-10 | 2023-08-02 | アキュタス ダイアグノスティクス,インク. | 血液及び体液からの微生物の単離及び迅速検出のための方法及び組成物 |
| US20230302454A1 (en) | 2020-08-13 | 2023-09-28 | Streck, Inc. | Sample collection containers, processes and collected samples |
| CN112251358A (zh) * | 2020-10-23 | 2021-01-22 | 瑞因迈拓科技(广州)有限公司 | 一种用于病原微生物检测体液标本的保存剂及其应用 |
| CN112501159A (zh) * | 2020-12-04 | 2021-03-16 | 麦凯(上海)生物科技有限公司 | 一种通用型游离核酸保护剂 |
| EP4263383A4 (en) | 2020-12-17 | 2024-10-23 | Nephrosant, Inc. | KITS FOR STABILIZATION OF URINE SAMPLES |
| WO2022150283A1 (en) * | 2021-01-05 | 2022-07-14 | Nuclease Probe Technologies, Inc. | Sars-cov-2 detection |
| CN112760360B (zh) * | 2021-03-22 | 2023-12-19 | 洛阳赛奥生物工程技术有限公司 | 一种rna保护剂及其应用 |
| EP4394028A4 (en) * | 2021-08-25 | 2025-08-06 | Sekisui Medical Co Ltd | STORAGE SOLUTION FOR CELL-CONTAINING SOLUTION AND STORAGE CONTAINER FOR CELL-CONTAINING SOLUTION |
| EP4547860A1 (en) * | 2022-06-29 | 2025-05-07 | Life Technologies Corporation | Systems and methods for analyte detection from multiplexed assays |
| KR102699668B1 (ko) * | 2022-07-22 | 2024-08-28 | 주식회사 어큐진 | 분변 rna 보존액 |
| EP4356731A1 (en) * | 2022-10-19 | 2024-04-24 | Olga Alekseevna Gra | Medium and device for collecting, storing and transporting biological samples, as well as their use for the stabilization of extracellular nucleic acids |
| GB202303562D0 (en) | 2023-03-10 | 2023-04-26 | Belgian Volition Sprl | Sample collection for liquid biopsy |
| WO2024192232A1 (en) | 2023-03-14 | 2024-09-19 | Streck Llc | Compositions and uses thereof for stabilization of blood sample components |
| WO2025167593A1 (zh) * | 2024-02-06 | 2025-08-14 | 上海细胞治疗集团股份有限公司 | 生物样本的存储保护剂、采集卡、存储和检测方法 |
Family Cites Families (192)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1432249A (en) | 1922-02-06 | 1922-10-17 | Howard S Borden | Article of manufacture |
| US1922799A (en) | 1932-12-16 | 1933-08-15 | George E Gaus | Method for affixing identification tags |
| US2250666A (en) | 1938-10-31 | 1941-07-29 | Godefroy Mfg Company | Combined label, cap loosener, and auxiliary container |
| US2690624A (en) | 1949-09-15 | 1954-10-05 | Ollie W Phillips | Sign |
| US2930570A (en) | 1959-01-30 | 1960-03-29 | Herbert R Leedy | Pinch clamp |
| US3867521A (en) | 1970-08-26 | 1975-02-18 | Scherer Corp R P | Method for absorption of drugs |
| US3781120A (en) | 1970-09-14 | 1973-12-25 | Technicon Instr | Self-locating sample receptacle having integral identification label |
| US3874384A (en) | 1971-11-01 | 1975-04-01 | American Hospital Supply Corp | Improved blood storage unit and method of storing blood |
| US3872730A (en) | 1972-03-10 | 1975-03-25 | Becton Dickinson Co | Sampling apparatus |
| US3879295A (en) | 1973-08-17 | 1975-04-22 | Eastman Kodak Co | Vacutainer with positive separation barrier |
| US3973913A (en) | 1976-01-29 | 1976-08-10 | Louderback Allan Lee | Blood control standard |
| US3994085A (en) | 1976-03-29 | 1976-11-30 | Groselak Robert E | Baggage tag |
| US4043453A (en) | 1976-05-11 | 1977-08-23 | The Wright Tool & Forge Company | Holder and display device for wrench sockets |
| US4318090A (en) | 1980-10-27 | 1982-03-02 | Sensormatic Electronics Corporation | Apparatus for deactivating a surveillance tag |
| US4513522A (en) | 1982-09-16 | 1985-04-30 | Selenke William M | Label with particular application to laboratory specimen container identification |
| US4515890A (en) | 1982-11-08 | 1985-05-07 | Abbott Laboratories | Immunoassay of terminal deoxynucleotidyl transferase |
| DE8407967U1 (de) | 1984-03-15 | 1984-06-07 | Idento - Gesellschaft für industrielle Kennzeichnung mbH, 6074 Rödermark | Beschriftbarer Kabelmarkierungsstreifen |
| US4584219A (en) | 1984-11-09 | 1986-04-22 | Baartmans Hans R | Web of labels |
| US4675159A (en) | 1985-09-29 | 1987-06-23 | Al Sioufi Habib | Method and device for disinfecting biological fluids and container for same |
| US5110908A (en) | 1986-12-31 | 1992-05-05 | Praxis Biologics, Inc. | Haemophilus influenzae peptides and proteins |
| US4884827A (en) | 1988-01-22 | 1989-12-05 | Norfolk Scientific Inc. | Partially transparent label |
| US4921277A (en) | 1988-10-24 | 1990-05-01 | Academy Of Applied Science, Inc. | Method of labeling needle syringes and medication vials and novel labels therefor |
| HU201865B (en) | 1989-04-28 | 1991-01-28 | Pecsi Dohanygyar | Tobacco-smoke filter of high efficiency |
| US5000484A (en) | 1989-08-30 | 1991-03-19 | Phelan James C | Identification and monitoring system for surgical specimens |
| US5153117A (en) | 1990-03-27 | 1992-10-06 | Genetype A.G. | Fetal cell recovery method |
| JP2540649B2 (ja) | 1990-04-27 | 1996-10-09 | テルモ株式会社 | 採血管 |
| US5250438A (en) | 1990-05-09 | 1993-10-05 | Streck Laboratories, Inc. | Method for differential determination of white blood cells using diazolidinyl urea to stabilize white blood cells |
| US5135125A (en) | 1991-02-15 | 1992-08-04 | Tapecon, Inc. | Hanging label |
| US5196182A (en) | 1991-05-08 | 1993-03-23 | Streck Laboratories, Inc. | Tissue fixative |
| US5459073A (en) | 1991-05-08 | 1995-10-17 | Streck Laboratories, Inc. | Method and composition for preserving antigens and process for utilizing cytological material produced by same |
| US5849517A (en) | 1991-05-08 | 1998-12-15 | Streck Laboratories, Inc. | Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same |
| US5260048A (en) | 1991-05-08 | 1993-11-09 | Streck Laboratories, Inc. | Tissue fixative solution and method |
| US5460797A (en) | 1991-05-08 | 1995-10-24 | Streck Laboratories, Inc. | Method for fixing tissues and cells for analysis using oxazolidine compounds |
| US5459253A (en) | 1991-07-19 | 1995-10-17 | Pharmacia P-L Biochemicals Inc. | M-RNA purification |
| US5343647A (en) | 1991-09-03 | 1994-09-06 | Moore Business Forms, Inc. | Pressure sensitive pricing tag/label |
| WO1993005650A1 (en) | 1991-09-20 | 1993-04-01 | Camiener Gerald W | Methods and compositions with aldehyde stabilizing solution |
| US5998483A (en) | 1991-09-20 | 1999-12-07 | Camiener; Gerald W. | Glyoxal-containing preservative compositions |
| DE4134231A1 (de) | 1991-10-16 | 1993-04-22 | Fix Gmbh | Gepaeckstreifenanhaenger fuer einzelbeschriftung |
| US5257633A (en) | 1992-06-23 | 1993-11-02 | Becton, Dickinson And Company | Surface modified blood collection tubes |
| US5629147A (en) | 1992-07-17 | 1997-05-13 | Aprogenex, Inc. | Enriching and identifying fetal cells in maternal blood for in situ hybridization |
| CA2140278C (en) | 1992-07-17 | 2009-03-17 | Morteza Asgari | Enriching and identyfing fetal cells in maternal blood for in situ hybridization |
| GB9223035D0 (en) | 1992-11-03 | 1992-12-16 | Kiessling Cooper Ann A | Preservation of peripheral blood & semen in fixatives that inactivate human pathogens |
| US5688516A (en) | 1992-11-12 | 1997-11-18 | Board Of Regents, The University Of Texas System | Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices |
| AU669754B2 (en) | 1992-12-18 | 1996-06-20 | Becton Dickinson & Company | Barrier coating |
| US5457024A (en) | 1993-01-22 | 1995-10-10 | Aprogenex, Inc. | Isolation of fetal erythrocytes |
| JP3615545B2 (ja) | 1993-02-01 | 2005-02-02 | キアゲン・エヌ・ブイ | 第四級アンモニウム塩界面活性剤及びそのrnaの単離剤 |
| NZ271318A (en) | 1993-07-05 | 1998-08-26 | North Gen Hospital Nhs Trust | Leukocyte cell preparations stabilised with heavy metal compounds |
| US6043032A (en) | 1993-09-22 | 2000-03-28 | Tosoh Corporation | Method of extracting nucleic acids and method of detecting specified nucleic acid sequences |
| JPH09510875A (ja) | 1994-03-29 | 1997-11-04 | ジェンザイム・コーポレイション | 母親の末梢血からの胎児細胞の培養および単離 |
| ATE170979T1 (de) | 1994-04-05 | 1998-09-15 | North Gen Hospital Nhs Trust | Herstellung und stabilisierung von zellsuspensionen |
| US5501954A (en) | 1994-06-13 | 1996-03-26 | Genzyme Corporation | Method of detecting cellular material |
| US5468022A (en) | 1994-06-14 | 1995-11-21 | Massachusetts Institute Of Technology | Sample tube identification flag |
| FR2722506B1 (fr) | 1994-07-13 | 1996-08-14 | Rhone Poulenc Rorer Sa | Composition contenant des acides nucleiques, preparation et utilisations |
| US5512343A (en) | 1994-08-01 | 1996-04-30 | Diagraph Corporation | Label assembly |
| US5540358A (en) | 1994-12-19 | 1996-07-30 | The Procter And Gamble Company | Flexible planar gusseted package for dispensing a product through a fitment |
| US5490658A (en) | 1995-03-02 | 1996-02-13 | Avery Dennison Corporation | Label hangers for intravenous bottles |
| US5560657A (en) | 1995-03-08 | 1996-10-01 | Morgan; Brian R. | Tamper-indicating label |
| USD382343S (en) | 1995-06-06 | 1997-08-12 | Home Access Health Corporation | Filmstrip for enhancing blood flow |
| US6527957B1 (en) | 1995-08-09 | 2003-03-04 | Baxter International Inc. | Methods for separating, collecting and storing red blood cells |
| US5817519A (en) | 1995-12-28 | 1998-10-06 | Bayer Corporation | Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples |
| US6630301B1 (en) | 1997-03-14 | 2003-10-07 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum |
| WO1997034015A1 (en) | 1996-03-15 | 1997-09-18 | The Penn State Research Foundation | Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays |
| US6759217B2 (en) | 1996-03-26 | 2004-07-06 | Oncomedx, Inc. | Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer |
| EP0938320B2 (en) | 1996-03-26 | 2014-06-18 | Michael S. Kopreski | Method enabling use of extracellular rna extracted from plasma or serum to detect, monitor or evaluate cancer |
| US6072086A (en) | 1996-04-12 | 2000-06-06 | Intergen Company | Method and composition for controlling formaldehyde fixation by delayed quenching |
| GB2313288B (en) | 1996-05-24 | 2000-07-12 | North Gen Hospital Nhs Trust | Specimen collection fluid |
| IT1294964B1 (it) | 1996-07-12 | 1999-04-23 | Domenico Valerio | Isolamento e cultura di cellule fetali dal sangue periferico materno |
| US6074827A (en) | 1996-07-30 | 2000-06-13 | Aclara Biosciences, Inc. | Microfluidic method for nucleic acid purification and processing |
| US5731156A (en) | 1996-10-21 | 1998-03-24 | Applied Imaging, Inc. | Use of anti-embryonic hemoglobin antibodies to identify fetal cells |
| US6190609B1 (en) | 1996-11-19 | 2001-02-20 | Baxter International Inc. | Methods and apparatus for inactivating contaminants in biological fluid |
| US5783093A (en) | 1997-01-02 | 1998-07-21 | Haemonetics Corporation | Blood cell concentrates using a single solution for anticoagulation and preservation |
| WO1998031219A1 (en) | 1997-01-21 | 1998-07-23 | The American National Red Cross | Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light |
| US6125563A (en) | 1997-02-14 | 2000-10-03 | Girerd; Philippe H. | Container label with handle flap |
| GB9704444D0 (en) | 1997-03-04 | 1997-04-23 | Isis Innovation | Non-invasive prenatal diagnosis |
| US20010051341A1 (en) | 1997-03-04 | 2001-12-13 | Isis Innovation Limited | Non-invasive prenatal diagnosis |
| ATE251306T1 (de) | 1997-03-25 | 2003-10-15 | Immunivest Corp | Gerät und methoden zum einfnag und zur analyse von partikel-einheiten |
| SE514350C2 (sv) | 1997-04-07 | 2001-02-12 | Resemino System Ab | Metod för affischering samt för metoden anpassat system för affischering |
| US5939259A (en) | 1997-04-09 | 1999-08-17 | Schleicher & Schuell, Inc. | Methods and devices for collecting and storing clinical samples for genetic analysis |
| US5906744A (en) | 1997-04-30 | 1999-05-25 | Becton Dickinson And Company | Tube for preparing a plasma specimen for diagnostic assays and method of making thereof |
| US5976014A (en) | 1997-05-28 | 1999-11-02 | Moore U.S.A., Inc. | Integrity seal form/label combination |
| EP1634966B1 (en) | 1997-05-30 | 2010-11-03 | TrovaGene, Inc. | Methods for detection of nucleic acid sequences in urine |
| US6083731A (en) * | 1997-06-24 | 2000-07-04 | Washington State University Research Foundation | Recombinant materials and methods for the production of limonene hydroxylases |
| JP2002507121A (ja) | 1997-06-25 | 2002-03-05 | プロメガ コーポレイション | Rnaの単離方法 |
| US5962234A (en) | 1997-10-20 | 1999-10-05 | Applied Imaging Corporation | Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells |
| CA2260402C (en) | 1998-01-22 | 2001-10-23 | Pierre Boisvert | Display card |
| US6210889B1 (en) | 1998-01-28 | 2001-04-03 | The Universite Laval | Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities |
| US20010018192A1 (en) | 1998-02-12 | 2001-08-30 | Terstappen Leon W.M.M. | Labeled cells for use as an internal functional control in rare cell detection assays |
| WO1999041613A1 (en) | 1998-02-12 | 1999-08-19 | Immunivest | Methods and reagents for the rapid and efficient isolation of circulating cancer cells |
| US6177163B1 (en) | 1998-06-22 | 2001-01-23 | Tricor Direct, Inc. | Markable repositionable adhesive sheet dispensing roll for use in an industrial setting |
| US6204375B1 (en) | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
| US20060204989A1 (en) * | 1998-09-22 | 2006-09-14 | Kopreski Michael S | Comparative analysis of extracellular RNA species |
| US20090233276A1 (en) | 1998-09-22 | 2009-09-17 | Oncomedx, Inc. | Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions |
| US6077235A (en) | 1999-02-23 | 2000-06-20 | Becton, Dickinson And Company | Blood collection assembly and method therefor |
| US7683035B1 (en) * | 1999-02-23 | 2010-03-23 | Qiagen, Gmbh | Method of stabilizing and/or isolating nucleic acids |
| EP1203227A4 (en) | 1999-06-04 | 2003-01-02 | Bioseparations Inc | PRENATAL DIAGNOSIS SCREENING SYSTEM AND METHOD |
| AU5620600A (en) | 1999-06-16 | 2001-01-02 | University Of Cincinnati, The | Agent and process for isolation of extra-chromosomal nucleic acids |
| DE19928820A1 (de) | 1999-06-17 | 2000-12-21 | Ulrich Groth | Fixiermittel für Zellen und Gewebe von Lebewesen |
| EP1377216A2 (en) | 1999-07-29 | 2004-01-07 | Baxter International Inc. | Sampling tube holder for blood sampling system |
| EP1220944B1 (en) | 1999-09-24 | 2010-09-15 | Ambion, Inc. | Nuclease inhibitor cocktail |
| US20010049895A1 (en) | 2000-01-06 | 2001-12-13 | Burke Doyle G. | Promotional hanger |
| US6337189B1 (en) | 2000-02-08 | 2002-01-08 | Streck Laboratories, Inc. | Fixative system, method and composition for biological testing |
| DE10006662A1 (de) | 2000-02-15 | 2001-08-23 | Antigen Produktions Gmbh | Gefäß zur Nukleinsäureanalytik |
| GB0009179D0 (en) | 2000-04-13 | 2000-05-31 | Imp College Innovations Ltd | Non-invasive prenatal diagnosis |
| GB0009784D0 (en) | 2000-04-20 | 2000-06-07 | Simeg Limited | Methods for clinical diagnosis |
| US20020045196A1 (en) | 2000-05-12 | 2002-04-18 | Walt Mahoney | Methods of isolating trophoblast cells from maternal blood |
| CA2686276C (en) | 2000-06-08 | 2015-08-11 | Stacy R. Kaufman | Verification of prescription information and warning label |
| CA2414102A1 (en) | 2000-06-21 | 2001-12-27 | Digene Corporation | Universal collection medium |
| WO2002011787A2 (en) | 2000-08-10 | 2002-02-14 | Baxa Corporation | Method, system, and apparatus for handling, labeling, filling, and capping syringes |
| US6664056B2 (en) | 2000-10-17 | 2003-12-16 | The Chinese University Of Hong Kong | Non-invasive prenatal monitoring |
| EP1326963B1 (en) | 2000-10-17 | 2008-05-21 | Zeptometrix Corporation | Microorganisms rendered non-pathogenic |
| US6551267B1 (en) | 2000-10-18 | 2003-04-22 | Becton, Dickinson And Company | Medical article having blood-contacting surface |
| CN100386441C (zh) | 2000-11-08 | 2008-05-07 | 贝克顿迪肯森公司 | 收集和稳定生物样品的装置、抑制体外基因诱导的方法和制备全血样品的方法 |
| US6602718B1 (en) | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
| EP1207208A3 (en) | 2000-11-15 | 2003-12-10 | Becton Dickinson and Company | Method for preservation of cells and nucleic acid targets |
| CA2428757A1 (en) | 2000-11-15 | 2002-07-18 | Roche Diagnostics Corporation | Methods and reagents for identifying rare fetal cells in the maternal circulation |
| US20020066216A1 (en) | 2000-12-01 | 2002-06-06 | Delacruz Cedric G. | Baby birth announcement |
| US6794152B2 (en) | 2000-12-22 | 2004-09-21 | Streck Laboratories Inc. | Flow cytometry reagent and system |
| US6581973B2 (en) | 2001-03-30 | 2003-06-24 | Cheringal Associates, Inc. | Double blind study label |
| US6617180B1 (en) | 2001-04-16 | 2003-09-09 | Taiwan Semiconductor Manufacturing Company | Test structure for detecting bridging of DRAM capacitors |
| FR2824144B1 (fr) | 2001-04-30 | 2004-09-17 | Metagenex S A R L | Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel |
| DE60239470D1 (de) | 2001-07-25 | 2011-04-28 | Oncomedx Inc | Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna |
| WO2008111981A1 (en) | 2007-03-14 | 2008-09-18 | Sierra Molecular Corporation | Compositions, systems, and methods for preservation of macromolecules |
| US7863012B2 (en) | 2004-02-17 | 2011-01-04 | Veridex, Llc | Analysis of circulating tumor cells, fragments, and debris |
| DE60227678D1 (de) | 2001-08-23 | 2008-08-28 | Immunivest Corp | Analyse zirkulierender tumorzellen, fragmente und trümmer |
| WO2003020116A2 (en) | 2001-08-31 | 2003-03-13 | University Of North Carolina At Chapel Hill | Fixed-dried red blood cells |
| US6527242B1 (en) | 2001-10-01 | 2003-03-04 | Netta Kennedy | Brace for a picture frame |
| ATE527004T1 (de) | 2002-02-01 | 2011-10-15 | Caridianbct Inc | System zur entnahme und aufbereitung von vollblut |
| GB0203280D0 (en) * | 2002-02-12 | 2002-03-27 | Ic Innovations Ltd | Anti-glycolytic composition |
| US20050107316A1 (en) | 2002-02-22 | 2005-05-19 | Klaus Strebhardt | Agent for inhibiting development or progress of proliferative diseases and especially cancer diseases and pharmaceutical composition containing said agent |
| GB2386038A (en) | 2002-02-27 | 2003-09-03 | Motorola Inc | Channel estimation in a radio receiver |
| US6977162B2 (en) | 2002-03-01 | 2005-12-20 | Ravgen, Inc. | Rapid analysis of variations in a genome |
| WO2003095974A2 (en) | 2002-05-07 | 2003-11-20 | Becton, Dickinson And Company | Collection assembly |
| US20070178478A1 (en) | 2002-05-08 | 2007-08-02 | Dhallan Ravinder S | Methods for detection of genetic disorders |
| US7442506B2 (en) | 2002-05-08 | 2008-10-28 | Ravgen, Inc. | Methods for detection of genetic disorders |
| US7022478B2 (en) * | 2002-05-14 | 2006-04-04 | The Chinese University Of Hong Kong | Methods for evaluating stroke or cardiac ischemia by nucleic acid detection |
| US20040014107A1 (en) | 2002-05-22 | 2004-01-22 | Garcia-Blanco Mariano A. | RNP immunoprecipitation assay |
| WO2003106623A2 (en) | 2002-06-13 | 2003-12-24 | New York University | Early noninvasive prenatal test for aneuploidies and heritable conditions |
| US6913932B2 (en) | 2002-08-23 | 2005-07-05 | Beckman Coulter, Inc. | Formaldehyde-ammonium salt complexes for the stabilization of blood cells |
| US20060008807A1 (en) | 2002-08-23 | 2006-01-12 | O'hara Shawn M | Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample |
| EP1816461B1 (en) | 2002-10-16 | 2020-01-08 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
| US10966421B2 (en) | 2002-10-16 | 2021-04-06 | Streck, Inc. | Method and device for collecting and preserving cells for analysis |
| KR100471183B1 (ko) | 2002-10-29 | 2005-03-10 | 삼성전자주식회사 | 오프 세트 트랜지스터를 갖는 반도체 기억소자 및 그제조방법 |
| AU2004217872B2 (en) | 2003-03-05 | 2010-03-25 | Genetic Technologies Limited | Identification of fetal DNA and fetal cell markers in maternal plasma or serum |
| US7267980B1 (en) | 2003-04-04 | 2007-09-11 | Research & Diagnostic Systems, Inc. | Stabilizing solution for cells and tissues |
| US20050277204A1 (en) | 2003-08-12 | 2005-12-15 | Massachusetts Institute Of Technology | Sample preparation methods and devices |
| US7318293B2 (en) | 2003-09-19 | 2008-01-15 | Ardern Ii William B | Binder clip sleeve |
| US20070111233A1 (en) | 2003-10-30 | 2007-05-17 | Bianchi Diana W | Prenatal diagnosis using cell-free fetal DNA in amniotic fluid |
| US20050181353A1 (en) | 2004-02-17 | 2005-08-18 | Rao Galla C. | Stabilization of cells and biological specimens for analysis |
| US20100216153A1 (en) | 2004-02-27 | 2010-08-26 | Helicos Biosciences Corporation | Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities |
| US20080119645A1 (en) | 2004-05-05 | 2008-05-22 | Isis Pharmaceuticals, Inc. | Amidites and Methods of Rna Synthesis |
| US8497134B2 (en) | 2004-08-19 | 2013-07-30 | Blood Cell Storage, Inc. | Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices |
| ES2251307B2 (es) * | 2004-10-05 | 2006-12-16 | Universidad Complutense De Madrid | Solucion para el mantenimiento indefinido de los acidos nucleicos en su celula de origen. |
| AU2005305012C1 (en) | 2004-11-05 | 2012-07-19 | Qiagen North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
| ATE481504T1 (de) | 2004-12-10 | 2010-10-15 | Siemens Healthcare Diagnostics | Für die vorhersage des ansprechens maligner neoplasie auf eine auf taxan beruhende medizinische behandlung geeignete genetische veränderung |
| US7390663B2 (en) | 2005-02-23 | 2008-06-24 | Streck, Inc. | Process, composition and kit for providing a stable whole blood calibrator/control |
| US7419832B2 (en) * | 2005-03-10 | 2008-09-02 | Streck, Inc. | Blood collection tube with surfactant |
| DE102005013261A1 (de) | 2005-03-22 | 2006-09-28 | Adnagen Ag | Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen |
| FI1899892T4 (fi) | 2005-05-20 | 2025-02-27 | Dental Imaging Technologies Corporation | Fokaalitason sijainti |
| WO2007022483A2 (en) | 2005-08-19 | 2007-02-22 | Bioventures, Inc. | Method and device for the collection and isolation of nucleic acid |
| WO2007053491A2 (en) | 2005-10-28 | 2007-05-10 | The Trustees Of Columbia University In The City Of New York | Method and kit for evaluating rna quality |
| EP2423334A3 (en) | 2006-02-02 | 2012-04-18 | The Board of Trustees of The Leland Stanford Junior University | Non-invasive fetal genetic screening by digital analysis |
| AU2007220991C1 (en) | 2006-02-28 | 2013-08-15 | University Of Louisville Research Foundation | Detecting fetal chromosomal abnormalities using tandem single nucleotide polymorphisms |
| US20070243548A1 (en) | 2006-03-28 | 2007-10-18 | Elias Georges | Calumenin-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance |
| US20070243549A1 (en) | 2006-04-12 | 2007-10-18 | Biocept, Inc. | Enrichment of circulating fetal dna |
| ES2264403B1 (es) | 2006-06-22 | 2007-11-01 | Grifols S.A. | Medio de suspension de hematies. |
| US20080081689A1 (en) | 2006-07-07 | 2008-04-03 | Atlantic City Coin & Slot Service Company, Inc. | Gaming device and method of use |
| CA2662837C (en) | 2006-08-30 | 2012-07-31 | Bioventures, Inc. | Methods and substances for isolation and detection of small polynucleotides |
| US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US20080108071A1 (en) | 2006-10-10 | 2008-05-08 | Katherine Thompson | Methods and Systems to Determine Fetal Sex and Detect Fetal Abnormalities |
| GB0704488D0 (en) | 2007-03-08 | 2007-04-18 | Univ Nottingham | Platelet viability kit |
| US8537789B2 (en) | 2007-08-01 | 2013-09-17 | Harris Corporation | Mobile ad-hoc network providing communication latency reduction features and related methods |
| WO2009042457A1 (en) | 2007-09-21 | 2009-04-02 | Streck, Inc. | Nucleic acid isolation in preserved whole blood |
| US20090308303A1 (en) | 2008-06-13 | 2009-12-17 | Burlando Albert A | Identification marker |
| CN102089752B (zh) | 2008-07-10 | 2014-05-07 | 洛克泰克科技有限公司 | 依赖性问题的有效率的并行计算 |
| WO2010078194A1 (en) * | 2008-12-30 | 2010-07-08 | Streck, Inc. | Method for screening blood using a preservative that may be in a substantially solid state form |
| US11634747B2 (en) * | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
| DE202010018569U1 (de) | 2009-02-18 | 2017-09-26 | Streck Inc. | Konservierung zellfreier Nukleinsäuren |
| EP2995953B1 (en) | 2009-03-24 | 2017-11-29 | Biocept, Inc. | Devices and methods of cell capture and analysis |
| US20110027771A1 (en) | 2009-07-31 | 2011-02-03 | Artemis Health, Inc. | Methods and compositions for cell stabilization |
| US20110053208A1 (en) | 2009-08-31 | 2011-03-03 | Streck, Inc. | Biological sample identification system |
| EP3103883A1 (en) | 2009-11-09 | 2016-12-14 | Streck, Inc. | Stabilization of rna in and extracting from intact cells within a blood sample |
| JP5876834B2 (ja) | 2010-01-04 | 2016-03-02 | キアジェン ゲイサーズバーグ インコーポレイテッド | 固定された組織サンプルからの核酸またはタンパク質の回収のための方法、組成物、およびキット |
| WO2012040603A2 (en) | 2010-09-23 | 2012-03-29 | Biocept, Inc. | Use of diazolidinyl urea for anti-clumping of biological samples |
| US20130316218A1 (en) | 2010-10-07 | 2013-11-28 | Schott Ag | Electrochemical energy accumulator |
| WO2012066913A1 (ja) | 2010-11-16 | 2012-05-24 | Ntn株式会社 | 転がり軸受および転がり軸受の製造方法 |
| WO2012145662A1 (en) | 2011-04-21 | 2012-10-26 | Streck, Inc. | Improved sample tube having particular utility for nucleic acid amplification |
| CA2835654A1 (en) | 2011-06-01 | 2012-12-06 | Streck, Inc. | Rapid thermocycler system for rapid amplification of nucleic acids and related methods |
| CN104428677A (zh) | 2011-12-09 | 2015-03-18 | 斯克利普斯研究所 | 用于识别循环肿瘤细胞的设备、系统和方法 |
| EP3789499B1 (en) | 2012-02-13 | 2023-03-15 | Streck, Inc. | Blood collection device for improved nucleic acid regulation |
| WO2014029791A1 (en) | 2012-08-21 | 2014-02-27 | Qiagen Gmbh | Method for isolating nucleic acids from a formaldehyde releaser stabilized sample |
| CA2839051A1 (en) | 2013-01-14 | 2014-07-14 | Streck, Inc. | Blood collection device for stabilizing cell-free rna in blood during sample shipping and storage |
| WO2015013244A1 (en) | 2013-07-24 | 2015-01-29 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
-
2010
- 2010-02-11 DE DE202010018569.6U patent/DE202010018569U1/de not_active Expired - Lifetime
- 2010-02-11 NO NO10704474A patent/NO2398912T3/no unknown
- 2010-02-11 US US12/704,030 patent/US8304187B2/en active Active
- 2010-02-11 EP EP17185367.4A patent/EP3290530B1/en active Active
- 2010-02-11 WO PCT/US2010/023859 patent/WO2010096323A1/en not_active Ceased
- 2010-02-11 DK DK17185367.4T patent/DK3290530T3/da active
- 2010-02-11 EP EP10704474.5A patent/EP2398912B1/en not_active Not-in-force
- 2010-02-11 EP EP20193258.9A patent/EP3778919A1/en not_active Withdrawn
- 2010-02-11 DK DK10704474.5T patent/DK2398912T3/en active
- 2010-02-11 ES ES10704474.5T patent/ES2649572T3/es active Active
-
2012
- 2012-10-10 US US13/648,415 patent/US8586306B2/en not_active Expired - Fee Related
-
2013
- 2013-11-05 US US14/071,969 patent/US9657227B2/en active Active
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2017
- 2017-05-22 US US15/601,682 patent/US9926590B2/en active Active
-
2018
- 2018-02-12 US US15/894,077 patent/US10144955B2/en active Active
- 2018-03-27 US US15/937,446 patent/US10294513B2/en active Active
-
2019
- 2019-04-08 US US16/377,344 patent/US10689686B2/en active Active
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2020
- 2020-06-22 US US16/908,233 patent/US11761025B2/en active Active
-
2023
- 2023-07-31 US US18/228,306 patent/US20230374568A1/en not_active Abandoned
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2024
- 2024-03-15 US US18/606,919 patent/US20240218425A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US10294513B2 (en) | 2019-05-21 |
| US20140054508A1 (en) | 2014-02-27 |
| WO2010096323A1 (en) | 2010-08-26 |
| EP2398912A1 (en) | 2011-12-28 |
| EP3778919A1 (en) | 2021-02-17 |
| US20180216165A1 (en) | 2018-08-02 |
| US10689686B2 (en) | 2020-06-23 |
| NO2398912T3 (enExample) | 2018-02-10 |
| EP2398912B1 (en) | 2017-09-13 |
| US11761025B2 (en) | 2023-09-19 |
| EP3290530B1 (en) | 2020-09-02 |
| US20170260569A1 (en) | 2017-09-14 |
| US20130034860A1 (en) | 2013-02-07 |
| EP3290530A1 (en) | 2018-03-07 |
| US10144955B2 (en) | 2018-12-04 |
| US20240218425A1 (en) | 2024-07-04 |
| US20180163256A1 (en) | 2018-06-14 |
| US20230374568A1 (en) | 2023-11-23 |
| US9926590B2 (en) | 2018-03-27 |
| ES2649572T3 (es) | 2018-01-12 |
| DE202010018569U1 (de) | 2017-09-26 |
| DK2398912T3 (en) | 2017-10-30 |
| US8304187B2 (en) | 2012-11-06 |
| US8586306B2 (en) | 2013-11-19 |
| US20200318161A1 (en) | 2020-10-08 |
| US9657227B2 (en) | 2017-05-23 |
| US20190233879A1 (en) | 2019-08-01 |
| US20100209930A1 (en) | 2010-08-19 |
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