BR9306867A - Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ - Google Patents

Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ

Info

Publication number
BR9306867A
BR9306867A BR9306867A BR9306867A BR9306867A BR 9306867 A BR9306867 A BR 9306867A BR 9306867 A BR9306867 A BR 9306867A BR 9306867 A BR9306867 A BR 9306867A BR 9306867 A BR9306867 A BR 9306867A
Authority
BR
Brazil
Prior art keywords
enrichment
identification
blood cells
situ hybridization
maternal blood
Prior art date
Application number
BR9306867A
Other languages
English (en)
Inventor
Nagindra Prashad
Morteza Asgari
Michael Lee Cubbage
Joel Bresser
Shyh Chen Ju
Mark Blick
Original Assignee
Aprogenex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aprogenex Inc filed Critical Aprogenex Inc
Publication of BR9306867A publication Critical patent/BR9306867A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6841—In situ hybridisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
BR9306867A 1992-07-17 1993-07-19 Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ BR9306867A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91596592A 1992-07-17 1992-07-17
PCT/US1993/006828 WO1994002646A1 (en) 1992-07-17 1993-07-19 Enriching and identyfying fetal cells in maternal blood for in situ hybridization

Publications (1)

Publication Number Publication Date
BR9306867A true BR9306867A (pt) 1998-12-08

Family

ID=25436486

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9306867A BR9306867A (pt) 1992-07-17 1993-07-19 Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ

Country Status (6)

Country Link
EP (1) EP0662152A1 (pt)
JP (1) JPH07509136A (pt)
AU (1) AU4685593A (pt)
BR (1) BR9306867A (pt)
CA (1) CA2140278C (pt)
WO (1) WO1994002646A1 (pt)

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US5457024A (en) * 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
US6136540A (en) 1994-10-03 2000-10-24 Ikonisys Inc. Automated fluorescence in situ hybridization detection of genetic abnormalities
US5501954A (en) * 1994-06-13 1996-03-26 Genzyme Corporation Method of detecting cellular material
GB9422504D0 (en) * 1994-11-08 1995-01-04 Robertson Patricia M B Blood testing
US5750339A (en) * 1994-11-30 1998-05-12 Thomas Jefferson University Methods for identifying fetal cells
US5998596A (en) * 1995-04-04 1999-12-07 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of protein kinase activity by aptameric action of oligonucleotides
EP0891550A1 (en) * 1996-04-05 1999-01-20 The Johns Hopkins University School Of Medicine A method of enriching rare cells
FR2751989B1 (fr) * 1996-08-01 1998-10-30 Soc D Rech Et De Dev En Activa Methode d'identification de cellules eucaryotes par fixation desdites cellules sur un support et support pour mettre en oeuvre ladite methode
US5731156A (en) * 1996-10-21 1998-03-24 Applied Imaging, Inc. Use of anti-embryonic hemoglobin antibodies to identify fetal cells
WO1998037919A1 (en) * 1997-02-28 1998-09-03 University Of Iowa Research Foundation USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
GB9807045D0 (en) * 1998-04-01 1998-06-03 Rudi Knut Nucleic acid detection method
US7901887B2 (en) 1998-05-09 2011-03-08 Ikonisys, Inc. Automated cancer diagnostic methods using fish
AU754722B2 (en) 1998-05-09 2002-11-21 Ikonisys Inc. Method and apparatus for computer controlled rare cell, including fetal cell, based diagnosis
JP2002529704A (ja) * 1998-10-29 2002-09-10 セル ワークス インコーポレイテッド 単一細胞の複数マーカー特徴付け
US6221596B1 (en) * 1999-05-17 2001-04-24 Motobit Ltd. System and method for identifying and isolating rare cells from a mixed population of cells
WO2001033190A2 (en) * 1999-11-04 2001-05-10 Arcturus Engineering, Inc. Automated laser capture microdissection
US20060073509A1 (en) * 1999-11-18 2006-04-06 Michael Kilpatrick Method for detecting and quantitating multiple subcellular components
WO2001037192A1 (en) * 1999-11-18 2001-05-25 Ikonisys, Inc. Method and apparatus for computer controlled cell based diagnosis
US6692965B1 (en) * 1999-11-23 2004-02-17 Chromocell Corporation Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences
GB0009784D0 (en) * 2000-04-20 2000-06-07 Simeg Limited Methods for clinical diagnosis
GB0016742D0 (en) * 2000-07-10 2000-08-30 Simeg Limited Diagnostic method
US7083924B2 (en) 2000-07-10 2006-08-01 Btg International Limited Diagnostic method for the identification of foetal DNA in a material sample
EP1405058A4 (en) 2001-03-19 2007-07-04 Ikonisys Inc SYSTEM AND METHOD FOR INCREASING THE CONTRAST OF AN IMAGE PRODUCED BY AN EPIFLUORESCENT MICROSCOPE
US10156501B2 (en) 2001-11-05 2018-12-18 Life Technologies Corporation Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
WO2005079462A2 (en) 2004-02-18 2005-09-01 Chromocell Corporation Methods and materials using signaling probes
JP2008543277A (ja) * 2005-05-11 2008-12-04 ジェネティック テクノロジーズ リミテッド 胎児細胞を富化する方法
KR20090074155A (ko) 2006-08-04 2009-07-06 아이코니시스 인코포레이티드 현미경 시스템의 이미지 처리 방법
JP2009072198A (ja) * 2008-10-24 2009-04-09 Chromocell Corp ｍＲＮＡ結合プローブを用いる生存細胞の選択および単離
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
US20100298453A1 (en) * 2009-01-26 2010-11-25 Invista North America S.A R.L. Board stock foam having biobased content
EP3290530B1 (en) 2009-02-18 2020-09-02 Streck Inc. Preservation of cell-free nucleic acids
EA027314B1 (ru) 2010-11-09 2017-07-31 Арседи Байотек Апс Способы выделения фетальной клетки с эндотелиальными и эпителиальными свойствами и набор для их осуществления
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
WO2014201138A1 (en) * 2013-06-11 2014-12-18 Stelling James R Method for detection of fetal abnormalities
WO2015013244A1 (en) 2013-07-24 2015-01-29 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US9709556B2 (en) 2013-12-11 2017-07-18 Analiza, Inc. Devices and methods for determining and/or isolating circulating cancer cells
US20150160246A1 (en) 2013-12-11 2015-06-11 Analiza, Inc. Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
DK3289098T3 (da) * 2015-04-30 2024-04-02 Sakura Finetek Usa Inc Fremgangsmåder til at reducere fordampning ved forhøjet temperatur
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
JP6550471B2 (ja) * 2016-04-15 2019-07-24 サクラ ファインテック ユー．エス．エー．， インコーポレイテッド 蒸発低減方法およびこれに用いる試薬
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
WO2023178295A1 (en) 2022-03-18 2023-09-21 Ludwig Institute For Cancer Research Ltd Methods and systems for analyzing chromatins

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Publication number Priority date Publication date Assignee Title
US4727021A (en) * 1984-06-01 1988-02-23 Sloan-Kettering Institute For Cancer Research Human monoclonal antibodies to cytokeratin
ATE153705T1 (de) * 1988-08-31 1997-06-15 Aprogenex Inc Einstufiges in situ-hybridierungstestverfahren
JPH04505556A (ja) * 1989-03-07 1992-10-01 シンジェン，インコーポレイテッド 細胞の検出または分離のための浮遊状態におけるインシトゥハイブリッド形成法
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method

Also Published As

Publication number Publication date
CA2140278C (en) 2009-03-17
EP0662152A1 (en) 1995-07-12
JPH07509136A (ja) 1995-10-12
WO1994002646A1 (en) 1994-02-03
AU4685593A (en) 1994-02-14
CA2140278A1 (en) 1994-02-03

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Legal Events

Date Code Title Description
FA7 Application deemed withdrawn (art. 18 par. 1 of law 5772/71) - being contrary to morals, good customs and public security, order and health