AU4685593A - Enriching and identyfying fetal cells in maternal blood for in situ hybridization - Google Patents
Enriching and identyfying fetal cells in maternal blood for in situ hybridizationInfo
- Publication number
- AU4685593A AU4685593A AU46855/93A AU4685593A AU4685593A AU 4685593 A AU4685593 A AU 4685593A AU 46855/93 A AU46855/93 A AU 46855/93A AU 4685593 A AU4685593 A AU 4685593A AU 4685593 A AU4685593 A AU 4685593A
- Authority
- AU
- Australia
- Prior art keywords
- fetal
- cells
- chromosome
- probe
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6841—In situ hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/36—Gynecology or obstetrics
- G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Urology & Nephrology (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91596592A | 1992-07-17 | 1992-07-17 | |
US915965 | 1992-07-17 | ||
PCT/US1993/006828 WO1994002646A1 (en) | 1992-07-17 | 1993-07-19 | Enriching and identyfying fetal cells in maternal blood for in situ hybridization |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4685593A true AU4685593A (en) | 1994-02-14 |
Family
ID=25436486
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU46855/93A Abandoned AU4685593A (en) | 1992-07-17 | 1993-07-19 | Enriching and identyfying fetal cells in maternal blood for in situ hybridization |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0662152A1 (pt) |
JP (1) | JPH07509136A (pt) |
AU (1) | AU4685593A (pt) |
BR (1) | BR9306867A (pt) |
CA (1) | CA2140278C (pt) |
WO (1) | WO1994002646A1 (pt) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5457024A (en) * | 1993-01-22 | 1995-10-10 | Aprogenex, Inc. | Isolation of fetal erythrocytes |
US6136540A (en) * | 1994-10-03 | 2000-10-24 | Ikonisys Inc. | Automated fluorescence in situ hybridization detection of genetic abnormalities |
US5501954A (en) * | 1994-06-13 | 1996-03-26 | Genzyme Corporation | Method of detecting cellular material |
GB9422504D0 (en) | 1994-11-08 | 1995-01-04 | Robertson Patricia M B | Blood testing |
US5750339A (en) * | 1994-11-30 | 1998-05-12 | Thomas Jefferson University | Methods for identifying fetal cells |
US5998596A (en) * | 1995-04-04 | 1999-12-07 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibition of protein kinase activity by aptameric action of oligonucleotides |
JP2000508171A (ja) * | 1996-04-05 | 2000-07-04 | ザ・ジョンズ・ホプキンス・ユニバーシティ・スクール・オブ・メディシン | 希少細胞の富化方法 |
FR2751989B1 (fr) * | 1996-08-01 | 1998-10-30 | Soc D Rech Et De Dev En Activa | Methode d'identification de cellules eucaryotes par fixation desdites cellules sur un support et support pour mettre en oeuvre ladite methode |
US5731156A (en) * | 1996-10-21 | 1998-03-24 | Applied Imaging, Inc. | Use of anti-embryonic hemoglobin antibodies to identify fetal cells |
WO1998037919A1 (en) * | 1997-02-28 | 1998-09-03 | University Of Iowa Research Foundation | USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS |
GB9807045D0 (en) * | 1998-04-01 | 1998-06-03 | Rudi Knut | Nucleic acid detection method |
US7901887B2 (en) | 1998-05-09 | 2011-03-08 | Ikonisys, Inc. | Automated cancer diagnostic methods using fish |
KR100691043B1 (ko) | 1998-05-09 | 2007-03-09 | 아이코니시스 인코포레이티드 | 컴퓨터 제어된 태아 세포 포함 희귀 세포 진단 방법 및 장치 |
GB2361996B (en) * | 1998-10-29 | 2004-05-12 | Cell Works Inc | Multiple marker characterization of single cells |
US6221596B1 (en) * | 1999-05-17 | 2001-04-24 | Motobit Ltd. | System and method for identifying and isolating rare cells from a mixed population of cells |
AU2922701A (en) * | 1999-11-04 | 2001-05-14 | Arcturus Engineering, Inc. | Automated laser capture microdissection |
AU1918100A (en) | 1999-11-18 | 2001-05-30 | Ikonisys Inc. | Method and apparatus for computer controlled cell based diagnosis |
US20060073509A1 (en) * | 1999-11-18 | 2006-04-06 | Michael Kilpatrick | Method for detecting and quantitating multiple subcellular components |
US6692965B1 (en) * | 1999-11-23 | 2004-02-17 | Chromocell Corporation | Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences |
GB0009784D0 (en) | 2000-04-20 | 2000-06-07 | Simeg Limited | Methods for clinical diagnosis |
US7083924B2 (en) | 2000-07-10 | 2006-08-01 | Btg International Limited | Diagnostic method for the identification of foetal DNA in a material sample |
GB0016742D0 (en) * | 2000-07-10 | 2000-08-30 | Simeg Limited | Diagnostic method |
US6956695B2 (en) | 2001-03-19 | 2005-10-18 | Ikonisys, Inc. | System and method for increasing the contrast of an image produced by an epifluorescence microscope |
US10156501B2 (en) | 2001-11-05 | 2018-12-18 | Life Technologies Corporation | Automated microdissection instrument for determining a location of a laser beam projection on a worksurface area |
EP1413874A1 (en) | 2002-10-16 | 2004-04-28 | Streck Laboratories, Inc. | Method and device for collecting and preserving cells for analysis |
CN104109712A (zh) | 2004-02-18 | 2014-10-22 | 克罗莫塞尔公司 | 使用信号探针的方法和材料 |
US20090305236A1 (en) * | 2005-05-11 | 2009-12-10 | Genetic Technologies Limited | Methods of enriching fetal cells |
JP2010500573A (ja) | 2006-08-04 | 2010-01-07 | イコニシス インコーポレーテッド | 顕微鏡システムのための画像処理方法 |
JP2009072198A (ja) * | 2008-10-24 | 2009-04-09 | Chromocell Corp | mRNA結合プローブを用いる生存細胞の選択および単離 |
US11634747B2 (en) | 2009-01-21 | 2023-04-25 | Streck Llc | Preservation of fetal nucleic acids in maternal plasma |
EP2389455A4 (en) * | 2009-01-26 | 2012-12-05 | Verinata Health Inc | METHODS AND COMPOSITIONS FOR IDENTIFYING A FETAL CELL |
NO2398912T3 (pt) | 2009-02-18 | 2018-02-10 | ||
SI2638176T1 (en) | 2010-11-09 | 2018-01-31 | Arcedi Biotech Aps | Enrichment and determination of fetal cells in the mother's blood and ligands for such use |
EP2704740B1 (en) | 2011-05-04 | 2016-10-05 | Streck, Inc. | Inactivated swine flu virus and methods of preparing it |
WO2014201138A1 (en) * | 2013-06-11 | 2014-12-18 | Stelling James R | Method for detection of fetal abnormalities |
US10091984B2 (en) | 2013-07-24 | 2018-10-09 | Streck, Inc. | Compositions and methods for stabilizing circulating tumor cells |
US9709556B2 (en) | 2013-12-11 | 2017-07-18 | Analiza, Inc. | Devices and methods for determining and/or isolating circulating cancer cells |
US20150160246A1 (en) | 2013-12-11 | 2015-06-11 | Analiza, Inc. | Devices and methods for determining and/or isolating cells such as circulating cancer or fetal cells |
US11168351B2 (en) | 2015-03-05 | 2021-11-09 | Streck, Inc. | Stabilization of nucleic acids in urine |
DK3289098T3 (da) * | 2015-04-30 | 2024-04-02 | Sakura Finetek Usa Inc | Fremgangsmåder til at reducere fordampning ved forhøjet temperatur |
US20170145475A1 (en) | 2015-11-20 | 2017-05-25 | Streck, Inc. | Single spin process for blood plasma separation and plasma composition including preservative |
CA2983930C (en) * | 2016-04-15 | 2023-05-02 | Sakura Finetek U.S.A., Inc. | Methods to reduce evaporation during elevated temperature |
EP3491381A1 (en) | 2016-07-29 | 2019-06-05 | Streck, Inc. | Suspension composition for hematology analysis control |
CN112980779B (zh) * | 2021-05-20 | 2021-08-24 | 广州凯普医药科技有限公司 | 一种从孕妇宫颈脱落细胞中分离胎盘滋养层细胞的方法 |
WO2023178295A1 (en) | 2022-03-18 | 2023-09-21 | Ludwig Institute For Cancer Research Ltd | Methods and systems for analyzing chromatins |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4727021A (en) * | 1984-06-01 | 1988-02-23 | Sloan-Kettering Institute For Cancer Research | Human monoclonal antibodies to cytokeratin |
DE68928080T2 (de) * | 1988-08-31 | 1998-01-15 | Aprogenex Inc | Einstufiges in situ-hybridierungstestverfahren |
JPH04505556A (ja) * | 1989-03-07 | 1992-10-01 | シンジェン,インコーポレイテッド | 細胞の検出または分離のための浮遊状態におけるインシトゥハイブリッド形成法 |
US5153117A (en) * | 1990-03-27 | 1992-10-06 | Genetype A.G. | Fetal cell recovery method |
-
1993
- 1993-07-19 CA CA002140278A patent/CA2140278C/en not_active Expired - Lifetime
- 1993-07-19 BR BR9306867A patent/BR9306867A/pt not_active Application Discontinuation
- 1993-07-19 EP EP93917297A patent/EP0662152A1/en not_active Withdrawn
- 1993-07-19 JP JP6504652A patent/JPH07509136A/ja active Pending
- 1993-07-19 WO PCT/US1993/006828 patent/WO1994002646A1/en not_active Application Discontinuation
- 1993-07-19 AU AU46855/93A patent/AU4685593A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JPH07509136A (ja) | 1995-10-12 |
BR9306867A (pt) | 1998-12-08 |
WO1994002646A1 (en) | 1994-02-03 |
CA2140278C (en) | 2009-03-17 |
EP0662152A1 (en) | 1995-07-12 |
CA2140278A1 (en) | 1994-02-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2140278C (en) | Enriching and identyfing fetal cells in maternal blood for in situ hybridization | |
US5861253A (en) | Intracellular antigens for identifying fetal cells in maternal blood | |
WO1995003431A1 (en) | Enriching and identifying fetal cells in maternal blood for in situ hybridization | |
KR100523381B1 (ko) | 태아 세포를 동정하는데 사용되는 항배아 헤모글로빈 항체 | |
JP4404553B2 (ja) | 単離された母体血液の胎児細胞に対する出生前診断の方法 | |
US5714325A (en) | Prenatal diagnosis by isolation of fetal granulocytes from maternal blood | |
US5962234A (en) | Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells | |
US20030232377A1 (en) | Early noninvasive prenatal test for aneuploidies and heritable conditions | |
EP1172445A1 (en) | A method for direct genetic analysis of target cells by using fluorescence probes | |
JP2005515408A (ja) | 細胞標的分子を同定するための方法 | |
WO2000079005A1 (en) | High efficiency methods for combined immunocytochemistry and in-situ hybridization | |
WO1995009245A1 (en) | Methods for detecting and analyzing individual rare cells in a population | |
WO1994025873A1 (en) | Methods for enriching fetal progenitor cells from maternal blood | |
US20060105353A1 (en) | Non-invasive prenatal fetal cell diagnostic method | |
JP2000504213A (ja) | 細胞内成分を用いる無傷細胞の固相強化 | |
WO1999015892A1 (en) | Enrichment and identification of trophoblast cells in maternal peripheral blood | |
Bischoff et al. | Prenatal Diagnosis of Chromosomal Abnormalities Using Maternal Blood | |
MXPA99003697A (en) | Use of anti-embryonic hemoglobin antibodies to identify fetal cells |