DK3290530T3 - Konservering af cellefrie nukleinsyrer - Google Patents

Konservering af cellefrie nukleinsyrer Download PDF

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Publication number
DK3290530T3
DK3290530T3 DK17185367.4T DK17185367T DK3290530T3 DK 3290530 T3 DK3290530 T3 DK 3290530T3 DK 17185367 T DK17185367 T DK 17185367T DK 3290530 T3 DK3290530 T3 DK 3290530T3
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Denmark
Prior art keywords
preservation
cell
nucleic acids
free nucleic
free
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DK17185367.4T
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English (en)
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Rohan Fernando
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Streck Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/20—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing nitrogen and oxygen
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/125—Specific component of sample, medium or buffer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2527/00—Reactions demanding special reaction conditions
    • C12Q2527/127—Reactions demanding special reaction conditions the enzyme inhibitor or activator used
DK17185367.4T 2009-02-18 2010-02-11 Konservering af cellefrie nukleinsyrer DK3290530T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15347209P 2009-02-18 2009-02-18
EP10704474.5A EP2398912B1 (en) 2009-02-18 2010-02-11 Preservation of cell-free nucleic acids

Publications (1)

Publication Number Publication Date
DK3290530T3 true DK3290530T3 (da) 2020-12-07

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK10704474.5T DK2398912T3 (da) 2009-02-18 2010-02-11 Konservering af cellefrie nukleinsyrer
DK17185367.4T DK3290530T3 (da) 2009-02-18 2010-02-11 Konservering af cellefrie nukleinsyrer

Family Applications Before (1)

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DK10704474.5T DK2398912T3 (da) 2009-02-18 2010-02-11 Konservering af cellefrie nukleinsyrer

Country Status (7)

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US (9) US8304187B2 (da)
EP (3) EP3290530B1 (da)
DE (1) DE202010018569U1 (da)
DK (2) DK2398912T3 (da)
ES (1) ES2649572T3 (da)
NO (1) NO2398912T3 (da)
WO (1) WO2010096323A1 (da)

Families Citing this family (104)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US10083273B2 (en) 2005-07-29 2018-09-25 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US10081839B2 (en) 2005-07-29 2018-09-25 Natera, Inc System and method for cleaning noisy genetic data and determining chromosome copy number
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US8532930B2 (en) 2005-11-26 2013-09-10 Natera, Inc. Method for determining the number of copies of a chromosome in the genome of a target individual using genetic data from genetically related individuals
CA2731991C (en) 2008-08-04 2021-06-08 Gene Security Network, Inc. Methods for allele calling and ploidy calling
WO2010078194A1 (en) * 2008-12-30 2010-07-08 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) * 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
EP3290530B1 (en) 2009-02-18 2020-09-02 Streck Inc. Preservation of cell-free nucleic acids
EP2473638B1 (en) 2009-09-30 2017-08-09 Natera, Inc. Methods for non-invasive prenatal ploidy calling
ES2571104T3 (es) * 2009-11-09 2016-05-24 Streck Inc Estabilización del ARN y extracción del ARN presente en células intactas dentro de una muestra de sangre
WO2011113043A2 (en) * 2010-03-12 2011-09-15 University Of South Florida Sample storage for molecular and immunological detection
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
WO2011146632A1 (en) 2010-05-18 2011-11-24 Gene Security Network Inc. Methods for non-invasive prenatal ploidy calling
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
WO2012040603A2 (en) 2010-09-23 2012-03-29 Biocept, Inc. Use of diazolidinyl urea for anti-clumping of biological samples
JP6328934B2 (ja) 2010-12-22 2018-05-23 ナテラ， インコーポレイテッド 非侵襲性出生前親子鑑定法
AU2011358564B9 (en) 2011-02-09 2017-07-13 Natera, Inc Methods for non-invasive prenatal ploidy calling
WO2012151391A2 (en) 2011-05-04 2012-11-08 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
EP3150702B1 (en) 2011-06-19 2021-05-19 DNA Genotek, Inc. Devices, solutions and methods for sample collection
CA2849354C (en) * 2011-09-26 2021-11-09 Preanalytix Gmbh Stabilisation and isolation of extracellular nucleic acids
CN113388605A (zh) 2011-09-26 2021-09-14 凯杰有限公司 用于分离细胞外核酸的快速方法
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
ES2687126T3 (es) 2011-09-26 2018-10-23 Qiagen Gmbh Estabilización y aislamiento de ácidos nucleicos extracelulares
WO2013074927A1 (en) * 2011-11-16 2013-05-23 University Of Georgia Research Foundation, Inc. Method for isolating total rna from cells
EP3225699B1 (en) * 2012-02-13 2020-09-30 Streck, Inc. Blood collection device for improved nucleic acid regulation
DE102012101896A1 (de) * 2012-03-06 2013-09-12 Roberto Gerigk Formalinfreie Fixierungsmittel für histologische Färbungen von Gewebeproben
US10233508B2 (en) * 2012-08-21 2019-03-19 Qiagen Gmbh Virus particle stabilisation and method for isolating viral nucleic acids
US10724074B2 (en) 2012-09-25 2020-07-28 Qiagen Gmbh Stabilisation of biological samples
CA2839051A1 (en) * 2013-01-14 2014-07-14 Streck, Inc. Blood collection device for stabilizing cell-free rna in blood during sample shipping and storage
US10017807B2 (en) 2013-03-15 2018-07-10 Verinata Health, Inc. Generating cell-free DNA libraries directly from blood
EP3447141B1 (en) 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
CN105164258B (zh) 2013-03-18 2021-05-18 凯杰有限公司 细胞外核酸的稳定化和分离
WO2015013244A1 (en) 2013-07-24 2015-01-29 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
US9644232B2 (en) 2013-07-26 2017-05-09 General Electric Company Method and device for collection and amplification of circulating nucleic acids
WO2015048535A1 (en) 2013-09-27 2015-04-02 Natera, Inc. Prenatal diagnostic resting standards
US10262755B2 (en) 2014-04-21 2019-04-16 Natera, Inc. Detecting cancer mutations and aneuploidy in chromosomal segments
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
US20170009288A1 (en) 2014-02-03 2017-01-12 Thermo Fisher Scientific Baltics Uab Method for controlled dna fragmentation
AU2015233500B2 (en) 2014-03-18 2018-11-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
CN113774132A (zh) 2014-04-21 2021-12-10 纳特拉公司 检测染色体片段中的突变和倍性
EP3155395B1 (en) * 2014-06-10 2021-06-02 Biomatrica, INC. Methods and compositions for stabilization of nucleic acids in a blood sample at ambient temperatures
ES2786373T3 (es) 2014-06-10 2020-10-09 Biomatrica Inc Estabilización de trombocitos a temperaturas ambiente
US10604751B2 (en) 2014-07-02 2020-03-31 Siemens Healthcare Disgnostics Inc. Selective nucleic acid separation
DK3656875T3 (da) 2014-07-18 2021-12-13 Illumina Inc Ikke-invasiv prænatal diagnostik
CN107002132A (zh) 2014-11-14 2017-08-01 液体基因有限公司 循环无细胞rna用于诊断和/或监测癌症的用途
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
AU2016277476B2 (en) 2015-06-10 2022-07-21 Qiagen Gmbh Method for isolating extracellular nucleic acids using anion exchange particles
CN115161178A (zh) 2015-09-09 2022-10-11 集联健康有限公司 用于样品收集、稳定化和保存的系统、方法和装置
EP3377645B1 (en) 2015-11-20 2023-10-04 Qiagen GmbH Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
ES2946184T3 (es) 2015-12-08 2023-07-13 Biomatrica Inc Reducción de la velocidad de eritrosedimentación
DE102016102346A1 (de) 2016-02-10 2017-08-10 Biosepar Gesellschaft für Medizin- und Labortechnik mbH Fixativum
US11767522B2 (en) 2016-05-27 2023-09-26 Norgen Biotek Corp. Preservation of cell-free nucleic acids in biological samples
WO2018022991A1 (en) 2016-07-29 2018-02-01 Streck, Inc. Suspension composition for hematology analysis control
EP3500687A4 (en) 2016-08-17 2020-07-29 The Regents of the University of California NEW METHOD BASED ON AN IMMUNOSOND, ALLOWING THE EVALUATION OF AN ORGANIC DAMAGE STATUS BY AN ACELLULAR DNA ASSAY (CFDNA) BASED ON BIOFLUID
WO2018067517A1 (en) 2016-10-04 2018-04-12 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
US20210072255A1 (en) 2016-12-16 2021-03-11 The Brigham And Women's Hospital, Inc. System and method for protein corona sensor array for early detection of diseases
CA3049139A1 (en) 2017-02-21 2018-08-30 Natera, Inc. Compositions, methods, and kits for isolating nucleic acids
US20200102618A1 (en) * 2017-03-17 2020-04-02 Nantomics, Llc LIQUID BIOPSY FOR cfRNA
CA3062985A1 (en) * 2017-05-16 2018-11-22 The Chinese University Of Hong Kong Integrative single-cell and cell-free plasma rna analysis
US11168323B2 (en) 2017-06-01 2021-11-09 Nantomics Llc DNA stabilization of RNA
CA3067946A1 (en) * 2017-08-02 2019-02-07 Sarstedt Ag & Co. Kg Process and composition for the stabilization of cell-free nucleic acids and cells
WO2019079743A1 (en) 2017-10-19 2019-04-25 Streck, Inc. COMPOSITIONS FOR HEMOLYSIS AND REGULATION OF COAGULATION AND STABILIZATION OF EXTRACELLULAR VESICLES
AU2018365883A1 (en) 2017-11-07 2020-05-14 Nanthealth Labs, Inc. Targeted cell free nucleic acid analysis
CN108220417B (zh) * 2017-12-28 2021-08-13 广州市金圻睿生物科技有限责任公司 可稳定保存的染色体非整倍体检测试剂盒的质控品及应用
CN108220478B (zh) * 2017-12-28 2021-08-17 广州市金圻睿生物科技有限责任公司 可稳定保存的丙型肝炎病毒基因检测试剂盒的病毒质控品
CN108103054B (zh) * 2017-12-28 2020-10-02 广州市金圻睿生物科技有限责任公司 一种rna保存液及其用途
CN108048529B (zh) * 2017-12-28 2021-01-19 广州市金圻睿生物科技有限责任公司 一种可稳定保存的肺癌甲基化基因检测试剂盒的质控品及应用
CN108085391B (zh) * 2017-12-28 2021-01-19 广州市金圻睿生物科技有限责任公司 一种可稳定保存的肺癌融合基因检测试剂盒的rna质控品
WO2019210306A1 (en) * 2018-04-27 2019-10-31 Momenta Pharmaceuticals , Inc. Blood preparation
CN108893524A (zh) * 2018-06-04 2018-11-27 北京启衡星生物科技有限公司 血浆中游离dna的保护剂
US11525159B2 (en) 2018-07-03 2022-12-13 Natera, Inc. Methods for detection of donor-derived cell-free DNA
WO2020021119A1 (en) 2018-07-27 2020-01-30 F. Hoffmann-La Roche Ag Method of monitoring effectiveness of immunotherapy of cancer patients
WO2020051542A2 (en) 2018-09-07 2020-03-12 Illumina, Inc. A method to determine if a circulating fetal cell isolated from a pregnant mother is from either the current or a historical pregnancy
KR20230155589A (ko) 2018-11-07 2023-11-10 시어 인코퍼레이티드 단백질 코로나 분석을 위한 조성물, 방법 및 시스템 및 그것들의 용도
US20220074949A1 (en) 2018-12-27 2022-03-10 Streck, Inc. Methods of preparing samples for proteomic analysis
CN111378708B (zh) * 2018-12-28 2022-07-19 康码（上海）生物科技有限公司 一种体外无细胞蛋白合成体系及其应用
WO2020198209A1 (en) 2019-03-26 2020-10-01 Seer, Inc. Compositions, methods and systems for protein corona analysis from biofluids and uses thereof
CN110747193B (zh) * 2019-09-25 2021-08-31 广州市达瑞生物技术股份有限公司 一种基于二代测序平台的肺癌多基因联合检测试剂盒质控品
CN111117999A (zh) * 2019-12-18 2020-05-08 上海兰卫医学检验所股份有限公司 一种适用于液态活检技术的血浆exRNA提取保存方法
CN116157681A (zh) 2020-07-01 2023-05-23 斯特雷克股份有限公司 制备用于蛋白质组学分析的样品的方法
US20220011298A1 (en) * 2020-07-10 2022-01-13 Acutis Diagnostics, Inc. Methods and compositions for isolation and rapid detection of micro-organisms from blood and bodily fluids
US20230302454A1 (en) 2020-08-13 2023-09-28 Streck, Inc. Sample collection containers, processes and collected samples
CN112251358A (zh) * 2020-10-23 2021-01-22 瑞因迈拓科技(广州)有限公司 一种用于病原微生物检测体液标本的保存剂及其应用
CN112501159A (zh) * 2020-12-04 2021-03-16 麦凯(上海)生物科技有限公司 一种通用型游离核酸保护剂
EP4263383A1 (en) 2020-12-17 2023-10-25 Nephrosant, Inc. Kits for stabilization of urine samples
WO2022150283A1 (en) * 2021-01-05 2022-07-14 Nuclease Probe Technologies, Inc. Sars-cov-2 detection
CN112760360B (zh) * 2021-03-22 2023-12-19 洛阳赛奥生物工程技术有限公司 一种rna保护剂及其应用
KR20240046683A (ko) * 2021-08-25 2024-04-09 세키스이 메디칼 가부시키가이샤 세포 함유액용 보존액 및 세포 함유액용 보존 용기
WO2024006924A1 (en) * 2022-06-29 2024-01-04 Life Technologies Corporation Systems and methods for analyte detection from multiplexed assays
EP4356731A1 (en) * 2022-10-19 2024-04-24 Olga Alekseevna Gra Medium and device for collecting, storing and transporting biological samples, as well as their use for the stabilization of extracellular nucleic acids

Family Cites Families (192)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1432249A (en) 1922-02-06 1922-10-17 Howard S Borden Article of manufacture
US1922799A (en) * 1932-12-16 1933-08-15 George E Gaus Method for affixing identification tags
US2250666A (en) * 1938-10-31 1941-07-29 Godefroy Mfg Company Combined label, cap loosener, and auxiliary container
US2690624A (en) 1949-09-15 1954-10-05 Ollie W Phillips Sign
US2930570A (en) * 1959-01-30 1960-03-29 Herbert R Leedy Pinch clamp
US3867521A (en) 1970-08-26 1975-02-18 Scherer Corp R P Method for absorption of drugs
US3781120A (en) 1970-09-14 1973-12-25 Technicon Instr Self-locating sample receptacle having integral identification label
US3874384A (en) 1971-11-01 1975-04-01 American Hospital Supply Corp Improved blood storage unit and method of storing blood
US3872730A (en) 1972-03-10 1975-03-25 Becton Dickinson Co Sampling apparatus
US3879295A (en) 1973-08-17 1975-04-22 Eastman Kodak Co Vacutainer with positive separation barrier
US3973913A (en) 1976-01-29 1976-08-10 Louderback Allan Lee Blood control standard
US3994085A (en) 1976-03-29 1976-11-30 Groselak Robert E Baggage tag
US4043453A (en) * 1976-05-11 1977-08-23 The Wright Tool & Forge Company Holder and display device for wrench sockets
US4318090A (en) * 1980-10-27 1982-03-02 Sensormatic Electronics Corporation Apparatus for deactivating a surveillance tag
US4513522A (en) * 1982-09-16 1985-04-30 Selenke William M Label with particular application to laboratory specimen container identification
US4515890A (en) 1982-11-08 1985-05-07 Abbott Laboratories Immunoassay of terminal deoxynucleotidyl transferase
DE8407967U1 (de) * 1984-03-15 1984-06-07 Idento - Gesellschaft für industrielle Kennzeichnung mbH, 6074 Rödermark Beschriftbarer Kabelmarkierungsstreifen
US4584219A (en) * 1984-11-09 1986-04-22 Baartmans Hans R Web of labels
US4675159A (en) 1985-09-29 1987-06-23 Al Sioufi Habib Method and device for disinfecting biological fluids and container for same
US5110908A (en) 1986-12-31 1992-05-05 Praxis Biologics, Inc. Haemophilus influenzae peptides and proteins
US4884827A (en) 1988-01-22 1989-12-05 Norfolk Scientific Inc. Partially transparent label
US4921277A (en) * 1988-10-24 1990-05-01 Academy Of Applied Science, Inc. Method of labeling needle syringes and medication vials and novel labels therefor
HU201865B (en) 1989-04-28 1991-01-28 Pecsi Dohanygyar Tobacco-smoke filter of high efficiency
US5000484A (en) * 1989-08-30 1991-03-19 Phelan James C Identification and monitoring system for surgical specimens
US5153117A (en) * 1990-03-27 1992-10-06 Genetype A.G. Fetal cell recovery method
JP2540649B2 (ja) * 1990-04-27 1996-10-09 テルモ株式会社 採血管
US5250438A (en) 1990-05-09 1993-10-05 Streck Laboratories, Inc. Method for differential determination of white blood cells using diazolidinyl urea to stabilize white blood cells
US5135125A (en) * 1991-02-15 1992-08-04 Tapecon, Inc. Hanging label
US5260048A (en) 1991-05-08 1993-11-09 Streck Laboratories, Inc. Tissue fixative solution and method
US5459073A (en) 1991-05-08 1995-10-17 Streck Laboratories, Inc. Method and composition for preserving antigens and process for utilizing cytological material produced by same
US5196182A (en) 1991-05-08 1993-03-23 Streck Laboratories, Inc. Tissue fixative
US5849517A (en) 1991-05-08 1998-12-15 Streck Laboratories, Inc. Method and composition for preserving antigens and nucleic acids and process for utilizing cytological material produced by same
US5460797A (en) 1991-05-08 1995-10-24 Streck Laboratories, Inc. Method for fixing tissues and cells for analysis using oxazolidine compounds
US5459253A (en) 1991-07-19 1995-10-17 Pharmacia P-L Biochemicals Inc. M-RNA purification
US5343647A (en) * 1991-09-03 1994-09-06 Moore Business Forms, Inc. Pressure sensitive pricing tag/label
US5998483A (en) 1991-09-20 1999-12-07 Camiener; Gerald W. Glyoxal-containing preservative compositions
CA2119554C (en) 1991-09-20 2003-05-06 Gerald W. Camiener Method and compositions with aldehyde stabilizing solution
DE4134231A1 (de) 1991-10-16 1993-04-22 Fix Gmbh Gepaeckstreifenanhaenger fuer einzelbeschriftung
US5257633A (en) 1992-06-23 1993-11-02 Becton, Dickinson And Company Surface modified blood collection tubes
AU4685593A (en) 1992-07-17 1994-02-14 Aprogenex, Inc. Enriching and identyfying fetal cells in maternal blood for in situ hybridization
US5629147A (en) * 1992-07-17 1997-05-13 Aprogenex, Inc. Enriching and identifying fetal cells in maternal blood for in situ hybridization
GB9223035D0 (en) 1992-11-03 1992-12-16 Kiessling Cooper Ann A Preservation of peripheral blood & semen in fixatives that inactivate human pathogens
US5688516A (en) 1992-11-12 1997-11-18 Board Of Regents, The University Of Texas System Non-glycopeptide antimicrobial agents in combination with an anticoagulant, an antithrombotic or a chelating agent, and their uses in, for example, the preparation of medical devices
AU669754B2 (en) 1992-12-18 1996-06-20 Becton Dickinson & Company Barrier coating
US5457024A (en) 1993-01-22 1995-10-10 Aprogenex, Inc. Isolation of fetal erythrocytes
JP3615545B2 (ja) 1993-02-01 2005-02-02 キアゲン・エヌ・ブイ 第四級アンモニウム塩界面活性剤及びそのｒｎａの単離剤
CA2166729A1 (en) * 1993-07-05 1995-01-19 Vivian Granger Preparation and stabilisation of cells
US6043032A (en) * 1993-09-22 2000-03-28 Tosoh Corporation Method of extracting nucleic acids and method of detecting specified nucleic acid sequences
CA2183657A1 (en) 1994-03-29 1995-10-05 Karen Pavelka Culture and isolation of fetal cells from maternal peripheral blood
WO1995027203A1 (en) * 1994-04-05 1995-10-12 Northern General Hospital N.H.S. Trust Preparation and stabilisation of cell suspensions
US5501954A (en) * 1994-06-13 1996-03-26 Genzyme Corporation Method of detecting cellular material
US5468022A (en) 1994-06-14 1995-11-21 Massachusetts Institute Of Technology Sample tube identification flag
FR2722506B1 (fr) * 1994-07-13 1996-08-14 Rhone Poulenc Rorer Sa Composition contenant des acides nucleiques, preparation et utilisations
US5512343A (en) * 1994-08-01 1996-04-30 Diagraph Corporation Label assembly
US5540358A (en) * 1994-12-19 1996-07-30 The Procter And Gamble Company Flexible planar gusseted package for dispensing a product through a fitment
US5490658A (en) * 1995-03-02 1996-02-13 Avery Dennison Corporation Label hangers for intravenous bottles
US5560657A (en) 1995-03-08 1996-10-01 Morgan; Brian R. Tamper-indicating label
USD382343S (en) * 1995-06-06 1997-08-12 Home Access Health Corporation Filmstrip for enhancing blood flow
US6527957B1 (en) * 1995-08-09 2003-03-04 Baxter International Inc. Methods for separating, collecting and storing red blood cells
US5817519A (en) 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6630301B1 (en) 1997-03-14 2003-10-07 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum
CA2248981C (en) 1996-03-15 2009-11-24 The Penn State Research Foundation Detection of extracellular tumor-associated nucleic acid in blood plasma or serum using nucleic acid amplification assays
PT938320E (pt) * 1996-03-26 2010-09-22 Michael S Kopreski Método que permite a utilização de arn extracelular extraído de plasma ou de soro para detectar, monitorizar ou avaliar o cancro
US6759217B2 (en) 1996-03-26 2004-07-06 Oncomedx, Inc. Method enabling use of extracellular RNA extracted from plasma or serum to detect, monitor or evaluate cancer
US6072086A (en) 1996-04-12 2000-06-06 Intergen Company Method and composition for controlling formaldehyde fixation by delayed quenching
GB2313288B (en) * 1996-05-24 2000-07-12 North Gen Hospital Nhs Trust Specimen collection fluid
IT1294964B1 (it) 1996-07-12 1999-04-23 Domenico Valerio Isolamento e cultura di cellule fetali dal sangue periferico materno
US6074827A (en) 1996-07-30 2000-06-13 Aclara Biosciences, Inc. Microfluidic method for nucleic acid purification and processing
US5731156A (en) * 1996-10-21 1998-03-24 Applied Imaging, Inc. Use of anti-embryonic hemoglobin antibodies to identify fetal cells
US6190609B1 (en) * 1996-11-19 2001-02-20 Baxter International Inc. Methods and apparatus for inactivating contaminants in biological fluid
US5783093A (en) * 1997-01-02 1998-07-21 Haemonetics Corporation Blood cell concentrates using a single solution for anticoagulation and preservation
US6030767A (en) * 1997-01-21 2000-02-29 The American National Red Cross Intracellular and extracellular decontamination of whole blood and blood components by amphiphilic phenothiazin-5-ium dyes plus light
US6125563A (en) 1997-02-14 2000-10-03 Girerd; Philippe H. Container label with handle flap
GB9704444D0 (en) * 1997-03-04 1997-04-23 Isis Innovation Non-invasive prenatal diagnosis
US20010051341A1 (en) 1997-03-04 2001-12-13 Isis Innovation Limited Non-invasive prenatal diagnosis
US6623983B1 (en) * 1997-03-25 2003-09-23 Immunivest Corporation Apparatus and methods for capture and analysis of particulate entities
SE514350C2 (sv) * 1997-04-07 2001-02-12 Resemino System Ab Metod för affischering samt för metoden anpassat system för affischering
US5939259A (en) * 1997-04-09 1999-08-17 Schleicher & Schuell, Inc. Methods and devices for collecting and storing clinical samples for genetic analysis
US5906744A (en) 1997-04-30 1999-05-25 Becton Dickinson And Company Tube for preparing a plasma specimen for diagnostic assays and method of making thereof
US5976014A (en) 1997-05-28 1999-11-02 Moore U.S.A., Inc. Integrity seal form/label combination
US6251638B1 (en) 1997-05-30 2001-06-26 Diagen Corporation Methods for detection of nucleic acid sequences in urine
US6083731A (en) 1997-06-24 2000-07-04 Washington State University Research Foundation Recombinant materials and methods for the production of limonene hydroxylases
WO1998059076A1 (en) * 1997-06-25 1998-12-30 Promega Corporation Method of isolating rna
US5962234A (en) 1997-10-20 1999-10-05 Applied Imaging Corporation Use of anti-embryonic epsilon hemoglobin antibodies to identify fetal cells
CA2260402C (en) 1998-01-22 2001-10-23 Pierre Boisvert Display card
US6210889B1 (en) * 1998-01-28 2001-04-03 The Universite Laval Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities
JP2002503814A (ja) 1998-02-12 2002-02-05 イムニベスト・コーポレイション 循環ガン細胞の迅速かつ効率的な単離のための方法および試薬
US20010018192A1 (en) * 1998-02-12 2001-08-30 Terstappen Leon W.M.M. Labeled cells for use as an internal functional control in rare cell detection assays
US6177163B1 (en) * 1998-06-22 2001-01-23 Tricor Direct, Inc. Markable repositionable adhesive sheet dispensing roll for use in an industrial setting
US6204375B1 (en) * 1998-07-31 2001-03-20 Ambion, Inc. Methods and reagents for preserving RNA in cell and tissue samples
US20060204989A1 (en) * 1998-09-22 2006-09-14 Kopreski Michael S Comparative analysis of extracellular RNA species
US20090233276A1 (en) 1998-09-22 2009-09-17 Oncomedx, Inc. Method Enabling the Use of Extracellular Ribonucleic Acid (RNA) Extracted from Plasma or Serum to Detect, Monitor or Evaluate Cancer or Premalignant Conditions
CA2299119C (en) 1999-02-23 2013-02-05 Qiagen Gmbh A method of stabilizing and/or isolating nucleic acids
US6077235A (en) * 1999-02-23 2000-06-20 Becton, Dickinson And Company Blood collection assembly and method therefor
EP1203227A4 (en) 1999-06-04 2003-01-02 Bioseparations Inc PRENATAL DIAGNOSIS SCREENING SYSTEM AND METHOD
AU5620600A (en) 1999-06-16 2001-01-02 University Of Cincinnati, The Agent and process for isolation of extra-chromosomal nucleic acids
DE19928820A1 (de) * 1999-06-17 2000-12-21 Ulrich Groth Fixiermittel für Zellen und Gewebe von Lebewesen
WO2001008546A2 (en) * 1999-07-29 2001-02-08 Baxter International Inc. Sampling tube holder for blood sampling system
DE60044977D1 (de) 1999-09-24 2010-10-28 Ambion Inc Cocktail von nukleaseinhibitoren
US20010049895A1 (en) 2000-01-06 2001-12-13 Burke Doyle G. Promotional hanger
US6337189B1 (en) 2000-02-08 2002-01-08 Streck Laboratories, Inc. Fixative system, method and composition for biological testing
DE10006662A1 (de) 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
GB0009179D0 (en) 2000-04-13 2000-05-31 Imp College Innovations Ltd Non-invasive prenatal diagnosis
GB0009784D0 (en) 2000-04-20 2000-06-07 Simeg Limited Methods for clinical diagnosis
US20020045196A1 (en) * 2000-05-12 2002-04-18 Walt Mahoney Methods of isolating trophoblast cells from maternal blood
CA2411077C (en) * 2000-06-08 2013-02-05 Stacy R. Kaufman Verification of prescription information and warning label
WO2001098542A2 (en) * 2000-06-21 2001-12-27 Digene Corporation Universal collection medium
US6813868B2 (en) * 2000-08-10 2004-11-09 Baxa Corporation Method, system, and apparatus for handling, labeling, filling and capping syringes
AU2002211795C1 (en) 2000-10-17 2008-04-17 Zeptometrix Corporation Nucleic acid amplification controls
US6664056B2 (en) 2000-10-17 2003-12-16 The Chinese University Of Hong Kong Non-invasive prenatal monitoring
US6551267B1 (en) 2000-10-18 2003-04-22 Becton, Dickinson And Company Medical article having blood-contacting surface
CA2428864C (en) 2000-11-08 2011-04-12 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
WO2002055985A2 (en) 2000-11-15 2002-07-18 Roche Diagnostics Corp Methods and reagents for identifying rare fetal cells in the material circulation
EP1207208A3 (en) 2000-11-15 2003-12-10 Becton Dickinson and Company Method for preservation of cells and nucleic acid targets
US20020066216A1 (en) * 2000-12-01 2002-06-06 Delacruz Cedric G. Baby birth announcement
US6794152B2 (en) 2000-12-22 2004-09-21 Streck Laboratories Inc. Flow cytometry reagent and system
US6581973B2 (en) * 2001-03-30 2003-06-24 Cheringal Associates, Inc. Double blind study label
US6617180B1 (en) * 2001-04-16 2003-09-09 Taiwan Semiconductor Manufacturing Company Test structure for detecting bridging of DRAM capacitors
FR2824144B1 (fr) * 2001-04-30 2004-09-17 Metagenex S A R L Methode de diagnostic prenatal sur cellule foetale isolee du sang maternel
DE60239470D1 (de) * 2001-07-25 2011-04-28 Oncomedx Inc Verfahren zur bewertung pathologischer krankheitszustände unter verwendung extrazellulärer rna
WO2008111981A1 (en) 2007-03-14 2008-09-18 Sierra Molecular Corporation Compositions, systems, and methods for preservation of macromolecules
EP1425383A4 (en) 2001-08-23 2005-11-09 Immunivest Corp STABILIZATION OF CELLS AND BIOLOGICAL PREPARATIONS FOR ANALYSIS
US7863012B2 (en) 2004-02-17 2011-01-04 Veridex, Llc Analysis of circulating tumor cells, fragments, and debris
AU2002329951A1 (en) * 2001-08-31 2003-03-18 University Of North Carolina At Chapel Hill Fixed-dried red blood cells
US6527242B1 (en) * 2001-10-01 2003-03-04 Netta Kennedy Brace for a picture frame
US6994790B2 (en) * 2002-02-01 2006-02-07 Gambro, Inc. Whole blood collection and processing method
GB0203280D0 (en) * 2002-02-12 2002-03-27 Ic Innovations Ltd Anti-glycolytic composition
WO2003070283A2 (en) 2002-02-22 2003-08-28 Klaus Strebhardt Agent for inhibiting development or progress of proliferative diseases and especially cancer diseases and pharmaceutical composition containing said agent
GB2386038A (en) 2002-02-27 2003-09-03 Motorola Inc Channel estimation in a radio receiver
US6977162B2 (en) * 2002-03-01 2005-12-20 Ravgen, Inc. Rapid analysis of variations in a genome
CA2484628A1 (en) 2002-05-07 2003-11-20 Becton, Dickinson And Company Collection assembly
US20070178478A1 (en) * 2002-05-08 2007-08-02 Dhallan Ravinder S Methods for detection of genetic disorders
US7442506B2 (en) 2002-05-08 2008-10-28 Ravgen, Inc. Methods for detection of genetic disorders
US7022478B2 (en) * 2002-05-14 2006-04-04 The Chinese University Of Hong Kong Methods for evaluating stroke or cardiac ischemia by nucleic acid detection
US20040014107A1 (en) 2002-05-22 2004-01-22 Garcia-Blanco Mariano A. RNP immunoprecipitation assay
WO2003106623A2 (en) 2002-06-13 2003-12-24 New York University Early noninvasive prenatal test for aneuploidies and heritable conditions
US6913932B2 (en) * 2002-08-23 2005-07-05 Beckman Coulter, Inc. Formaldehyde-ammonium salt complexes for the stabilization of blood cells
US20060008807A1 (en) * 2002-08-23 2006-01-12 O'hara Shawn M Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
CA2445204C (en) 2002-10-16 2014-08-12 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
EP1816461B1 (en) 2002-10-16 2020-01-08 Streck Laboratories, Inc. Method and device for collecting and preserving cells for analysis
KR100471183B1 (ko) * 2002-10-29 2005-03-10 삼성전자주식회사 오프 세트 트랜지스터를 갖는 반도체 기억소자 및 그제조방법
WO2004078999A1 (en) * 2003-03-05 2004-09-16 Genetic Technologies Limited Identification of fetal dna and fetal cell markers in maternal plasma or serum
US7267980B1 (en) 2003-04-04 2007-09-11 Research & Diagnostic Systems, Inc. Stabilizing solution for cells and tissues
US20050277204A1 (en) 2003-08-12 2005-12-15 Massachusetts Institute Of Technology Sample preparation methods and devices
US7318293B2 (en) * 2003-09-19 2008-01-15 Ardern Ii William B Binder clip sleeve
US20070111233A1 (en) * 2003-10-30 2007-05-17 Bianchi Diana W Prenatal diagnosis using cell-free fetal DNA in amniotic fluid
US20050181353A1 (en) * 2004-02-17 2005-08-18 Rao Galla C. Stabilization of cells and biological specimens for analysis
US20100216153A1 (en) 2004-02-27 2010-08-26 Helicos Biosciences Corporation Methods for detecting fetal nucleic acids and diagnosing fetal abnormalities
US20080119645A1 (en) * 2004-05-05 2008-05-22 Isis Pharmaceuticals, Inc. Amidites and Methods of Rna Synthesis
US8497134B2 (en) 2004-08-19 2013-07-30 Blood Cell Storage, Inc. Fluorescent detector systems for the detection of chemical perturbations in sterile storage devices
ES2251307B2 (es) * 2004-10-05 2006-12-16 Universidad Complutense De Madrid Solucion para el mantenimiento indefinido de los acidos nucleicos en su celula de origen.
KR20130143677A (ko) * 2004-11-05 2013-12-31 퀴아젠 노쓰 아메리칸 홀딩즈, 인크. 안정화 시약으로부터 핵산을 정제하기 위한 조성물 및 방법
JP2008524986A (ja) 2004-12-10 2008-07-17 バイエル・ヘルスケア・アクチェンゲゼルシャフト タキサンに基づく薬物療法に対する悪性腫瘍の応答予測に有用な遺伝子変化
US7390663B2 (en) 2005-02-23 2008-06-24 Streck, Inc. Process, composition and kit for providing a stable whole blood calibrator/control
US7419832B2 (en) 2005-03-10 2008-09-02 Streck, Inc. Blood collection tube with surfactant
DE102005013261A1 (de) 2005-03-22 2006-09-28 Adnagen Ag Reagenz und Verfahren zur Verhinderung der zeitabhängigen Expression in biologischen Zellen
EP1899921B1 (en) 2005-05-20 2018-05-02 Dental Imaging Technologies Corporation Panoramic view generator
EP1915447A4 (en) 2005-08-19 2008-07-30 Bioventures Inc METHOD AND DEVICE FOR COLLECTING AND ISOLATING NUCLEIC ACIDS
WO2007053491A2 (en) 2005-10-28 2007-05-10 The Trustees Of Columbia University In The City Of New York Method and kit for evaluating rna quality
US7888017B2 (en) * 2006-02-02 2011-02-15 The Board Of Trustees Of The Leland Stanford Junior University Non-invasive fetal genetic screening by digital analysis
ATE508209T1 (de) * 2006-02-28 2011-05-15 Univ Louisville Res Found Erkennung von chromosomabnormalitäten im fötus mit hilfe der tandem-einzelnukleotid- polymorphismen
US20070243548A1 (en) 2006-03-28 2007-10-18 Elias Georges Calumenin-directed diagnostics and therapeutics for cancer and chemotherapeutic drug resistance
US20070243549A1 (en) 2006-04-12 2007-10-18 Biocept, Inc. Enrichment of circulating fetal dna
ES2264403B1 (es) 2006-06-22 2007-11-01 Grifols S.A. Medio de suspension de hematies.
WO2008006086A2 (en) * 2006-07-07 2008-01-10 Atlantic City Coin & Slot Service Company, Inc. Gaming device and method of use
CN101528763B (zh) 2006-08-30 2012-06-27 生物风险公司 分离和检测小多核苷酸的方法和物质
US8080645B2 (en) 2007-10-01 2011-12-20 Longhorn Vaccines & Diagnostics Llc Biological specimen collection/transport compositions and methods
US20080108071A1 (en) * 2006-10-10 2008-05-08 Katherine Thompson Methods and Systems to Determine Fetal Sex and Detect Fetal Abnormalities
GB0704488D0 (en) * 2007-03-08 2007-04-18 Univ Nottingham Platelet viability kit
US8537789B2 (en) 2007-08-01 2013-09-17 Harris Corporation Mobile ad-hoc network providing communication latency reduction features and related methods
EP2191012A1 (en) * 2007-09-21 2010-06-02 Streck, Inc. Nucleic acid isolation in preserved whole blood
US20090308303A1 (en) 2008-06-13 2009-12-17 Burlando Albert A Identification marker
US8516454B2 (en) 2008-07-10 2013-08-20 Rocketick Technologies Ltd. Efficient parallel computation of dependency problems
WO2010078194A1 (en) * 2008-12-30 2010-07-08 Streck, Inc. Method for screening blood using a preservative that may be in a substantially solid state form
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
EP3290530B1 (en) 2009-02-18 2020-09-02 Streck Inc. Preservation of cell-free nucleic acids
WO2010111388A2 (en) 2009-03-24 2010-09-30 Biocept, Inc. Devices and methods of cell capture and analysis
WO2011014741A1 (en) 2009-07-31 2011-02-03 Artemis Health, Inc. Methods and compositions for cell stabilization
US20110053208A1 (en) * 2009-08-31 2011-03-03 Streck, Inc. Biological sample identification system
ES2571104T3 (es) 2009-11-09 2016-05-24 Streck Inc Estabilización del ARN y extracción del ARN presente en células intactas dentro de una muestra de sangre
EP2521778B1 (en) 2010-01-04 2014-03-19 QIAGEN Gaithersburg, Inc. Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples
WO2012040603A2 (en) 2010-09-23 2012-03-29 Biocept, Inc. Use of diazolidinyl urea for anti-clumping of biological samples
US20130316218A1 (en) 2010-10-07 2013-11-28 Schott Ag Electrochemical energy accumulator
WO2012066913A1 (ja) 2010-11-16 2012-05-24 Ntn株式会社 転がり軸受および転がり軸受の製造方法
WO2012145662A1 (en) 2011-04-21 2012-10-26 Streck, Inc. Improved sample tube having particular utility for nucleic acid amplification
CA2835654A1 (en) 2011-06-01 2012-12-06 Streck, Inc. Rapid thermocycler system for rapid amplification of nucleic acids and related methods
US20140329917A1 (en) 2011-12-09 2014-11-06 Gerd Marienfeld Apparatus, system and method for identifying circulating tumor cells
EP3225699B1 (en) 2012-02-13 2020-09-30 Streck, Inc. Blood collection device for improved nucleic acid regulation
US20150225712A1 (en) 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
CA2839051A1 (en) 2013-01-14 2014-07-14 Streck, Inc. Blood collection device for stabilizing cell-free rna in blood during sample shipping and storage
WO2015013244A1 (en) 2013-07-24 2015-01-29 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells

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