DK2718431T3 - dsRNA endoribonucleases. - Google Patents
dsRNA endoribonucleases. Download PDFInfo
- Publication number
- DK2718431T3 DK2718431T3 DK12735349.8T DK12735349T DK2718431T3 DK 2718431 T3 DK2718431 T3 DK 2718431T3 DK 12735349 T DK12735349 T DK 12735349T DK 2718431 T3 DK2718431 T3 DK 2718431T3
- Authority
- DK
- Denmark
- Prior art keywords
- dsrna
- endoribonuclease
- sequence
- seq
- cleavage
- Prior art date
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
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- C12P19/26—Preparation of nitrogen-containing carbohydrates
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- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| ES2952728T3 (es) | 2011-12-22 | 2023-11-03 | Harvard College | Métodos para la detección de analitos |
| WO2013184754A2 (en) | 2012-06-05 | 2013-12-12 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using dna origami probes |
| US10138509B2 (en) | 2013-03-12 | 2018-11-27 | President And Fellows Of Harvard College | Method for generating a three-dimensional nucleic acid containing matrix |
| RU2690935C2 (ru) | 2013-06-04 | 2019-06-06 | Президент Энд Фэллоуз Оф Харвард Коллидж | Направляемая рнк регуляция транскрипции |
| WO2016007839A1 (en) | 2014-07-11 | 2016-01-14 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| CN104306989A (zh) * | 2014-09-27 | 2015-01-28 | 郭和友 | 一种利用切割酶治疗细菌方法 |
| JP6882282B2 (ja) | 2015-11-03 | 2021-06-02 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 三次元核酸含有マトリックスの立体撮像のための方法と装置 |
| PL415883A1 (pl) * | 2016-01-22 | 2017-07-31 | Międzynarodowy Instytut Biologii Molekularnej I Komórkowej | RNazy MiniIII, sposoby zmiany specyficzności cięcia sekwencji RNA przez RNazy MiniIII oraz ich zastosowania |
| EP4613756A3 (en) | 2016-04-25 | 2025-11-12 | President And Fellows Of Harvard College | Hybridization chain reaction methods for in situ molecular detection |
| CN109923216B (zh) | 2016-08-31 | 2024-08-02 | 哈佛学院董事及会员团体 | 将生物分子的检测组合到使用荧光原位测序的单个试验的方法 |
| EP3507364A4 (en) | 2016-08-31 | 2020-05-20 | President and Fellows of Harvard College | METHODS OF GENERATING NUCLEIC ACID SEQUENCE LIBRARIES FOR IN SITU FLUORESCENT SEQUENCING DETECTION |
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| CN112770776B (zh) | 2018-07-30 | 2025-08-19 | 瑞德库尔有限责任公司 | 用于样品处理或分析的方法和系统 |
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| CN120098964A (zh) * | 2025-03-05 | 2025-06-06 | 中国科学院南海海洋研究所 | 高效热稳定的核糖核酸酶SiRe_0902在特异性识别GG位点中的应用 |
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| US20140087427A1 (en) | 2014-03-27 |
| PL395178A1 (pl) | 2012-12-17 |
| KR20140045371A (ko) | 2014-04-16 |
| EP2718431A1 (en) | 2014-04-16 |
| EP2718431B1 (en) | 2015-10-28 |
| CA2837143C (en) | 2016-01-05 |
| JP2014518641A (ja) | 2014-08-07 |
| CN103764821B (zh) | 2016-04-27 |
| ES2555661T3 (es) | 2016-01-07 |
| CN103764821A (zh) | 2014-04-30 |
| WO2012169917A1 (en) | 2012-12-13 |
| JP6075892B2 (ja) | 2017-02-08 |
| CA2837143A1 (en) | 2012-12-13 |
| AU2012267271A1 (en) | 2013-12-12 |
| AU2012267271B2 (en) | 2015-06-04 |
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