JP6075892B2 - 二本鎖ｒｎａエンドリボヌクレアーゼ - Google Patents

二本鎖ｒｎａエンドリボヌクレアーゼ Download PDF

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Publication number
JP6075892B2
JP6075892B2 JP2014514835A JP2014514835A JP6075892B2 JP 6075892 B2 JP6075892 B2 JP 6075892B2 JP 2014514835 A JP2014514835 A JP 2014514835A JP 2014514835 A JP2014514835 A JP 2014514835A JP 6075892 B2 JP6075892 B2 JP 6075892B2
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double
stranded rna
endoribonuclease
sequence
seq
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JP2014514835A
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Japanese (ja)
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JP2014518641A (ja
JP2014518641A5 (enExample
Inventor
ヤヌスズ マレク ブジニキ
ヤヌスズ マレク ブジニキ
イェルジ スコウロネク，クリストフ
イェルジ スコウロネク，クリストフ
ピアンカ，ダリウス
アグニエスカ スレジ，アガタ
アグニエスカ スレジ，アガタ
Original Assignee
ミエドジナロドウィ インスティタット バイオロジーモレキュラーネイ アイ コモルコウェイ
ミエドジナロドウィ インスティタット バイオロジーモレキュラーネイ アイ コモルコウェイ
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases [RNase]; Deoxyribonucleases [DNase]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/26—Endoribonucleases producing 5'-phosphomonoesters (3.1.26)
    • C12Y301/26003—Ribonuclease III (3.1.26.3)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2014514835A 2011-06-08 2012-06-07 二本鎖ｒｎａエンドリボヌクレアーゼ Expired - Fee Related JP6075892B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161494574P 2011-06-08 2011-06-08
PL395178A PL222511B1 (pl) 2011-06-08 2011-06-08 Endorybonukleazy dsRNA
PLP.395178 2011-06-08
US61/494,574 2011-06-08
PCT/PL2012/050020 WO2012169917A1 (en) 2011-06-08 2012-06-07 Dsrna endoribonucleases

Publications (3)

Publication Number Publication Date
JP2014518641A JP2014518641A (ja) 2014-08-07
JP2014518641A5 JP2014518641A5 (enExample) 2016-03-17
JP6075892B2 true JP6075892B2 (ja) 2017-02-08

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ID=47296271

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JP2014514835A Expired - Fee Related JP6075892B2 (ja) 2011-06-08 2012-06-07 二本鎖ｒｎａエンドリボヌクレアーゼ

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Country Link
US (1) US9238805B2 (enExample)
EP (1) EP2718431B1 (enExample)
JP (1) JP6075892B2 (enExample)
KR (1) KR20140045371A (enExample)
CN (1) CN103764821B (enExample)
AU (1) AU2012267271B2 (enExample)
CA (1) CA2837143C (enExample)
DK (1) DK2718431T3 (enExample)
ES (1) ES2555661T3 (enExample)
PL (1) PL222511B1 (enExample)
WO (1) WO2012169917A1 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014531908A (ja) 2011-10-14 2014-12-04 プレジデント アンド フェローズ オブ ハーバード カレッジ 構造アッセンブリによる配列決定
ES2991004T3 (es) 2011-12-22 2024-12-02 Harvard College Métodos para la detección de analitos
ES2952728T3 (es) 2011-12-22 2023-11-03 Harvard College Métodos para la detección de analitos
WO2013184754A2 (en) 2012-06-05 2013-12-12 President And Fellows Of Harvard College Spatial sequencing of nucleic acids using dna origami probes
US10138509B2 (en) 2013-03-12 2018-11-27 President And Fellows Of Harvard College Method for generating a three-dimensional nucleic acid containing matrix
RU2690935C2 (ru) 2013-06-04 2019-06-06 Президент Энд Фэллоуз Оф Харвард Коллидж Направляемая рнк регуляция транскрипции
WO2016007839A1 (en) 2014-07-11 2016-01-14 President And Fellows Of Harvard College Methods for high-throughput labelling and detection of biological features in situ using microscopy
CN104306989A (zh) * 2014-09-27 2015-01-28 郭和友 一种利用切割酶治疗细菌方法
JP6882282B2 (ja) 2015-11-03 2021-06-02 プレジデント アンド フェローズ オブ ハーバード カレッジ 三次元核酸含有マトリックスの立体撮像のための方法と装置
PL415883A1 (pl) * 2016-01-22 2017-07-31 Międzynarodowy Instytut Biologii Molekularnej I Komórkowej RNazy MiniIII, sposoby zmiany specyficzności cięcia sekwencji RNA przez RNazy MiniIII oraz ich zastosowania
EP4613756A3 (en) 2016-04-25 2025-11-12 President And Fellows Of Harvard College Hybridization chain reaction methods for in situ molecular detection
CN109923216B (zh) 2016-08-31 2024-08-02 哈佛学院董事及会员团体 将生物分子的检测组合到使用荧光原位测序的单个试验的方法
EP3507364A4 (en) 2016-08-31 2020-05-20 President and Fellows of Harvard College METHODS OF GENERATING NUCLEIC ACID SEQUENCE LIBRARIES FOR IN SITU FLUORESCENT SEQUENCING DETECTION
WO2018134386A1 (en) * 2017-01-23 2018-07-26 Novozymes A/S Host cells and methods for producing double-stranded rna
CN112770776B (zh) 2018-07-30 2025-08-19 瑞德库尔有限责任公司 用于样品处理或分析的方法和系统
WO2020076976A1 (en) 2018-10-10 2020-04-16 Readcoor, Inc. Three-dimensional spatial molecular indexing
US20220049303A1 (en) 2020-08-17 2022-02-17 Readcoor, Llc Methods and systems for spatial mapping of genetic variants
CN120098964A (zh) * 2025-03-05 2025-06-06 中国科学院南海海洋研究所 高效热稳定的核糖核酸酶SiRe_0902在特异性识别GG位点中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5459392A (en) 1977-10-14 1979-05-12 Rikagaku Kenkyusho Novel nuclease and its preparation
US20060057590A1 (en) 2004-09-14 2006-03-16 Azeddine Si-Ammour RNA probes

Also Published As

Publication number Publication date
US9238805B2 (en) 2016-01-19
PL222511B1 (pl) 2016-08-31
US20140087427A1 (en) 2014-03-27
PL395178A1 (pl) 2012-12-17
KR20140045371A (ko) 2014-04-16
EP2718431A1 (en) 2014-04-16
EP2718431B1 (en) 2015-10-28
CA2837143C (en) 2016-01-05
JP2014518641A (ja) 2014-08-07
CN103764821B (zh) 2016-04-27
DK2718431T3 (en) 2015-11-16
ES2555661T3 (es) 2016-01-07
CN103764821A (zh) 2014-04-30
WO2012169917A1 (en) 2012-12-13
CA2837143A1 (en) 2012-12-13
AU2012267271A1 (en) 2013-12-12
AU2012267271B2 (en) 2015-06-04

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