DK19286A - Cykliske imidderivater af 2-(4-butylpiperazin-1-yl)-pyridiner - Google Patents

Cykliske imidderivater af 2-(4-butylpiperazin-1-yl)-pyridiner Download PDF

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Publication number
DK19286A
DK19286A DK19286A DK19286A DK19286A DK 19286 A DK19286 A DK 19286A DK 19286 A DK19286 A DK 19286A DK 19286 A DK19286 A DK 19286A DK 19286 A DK19286 A DK 19286A
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DK
Denmark
Prior art keywords
imiderivatives
butylpiperazin
pyridines
cyclic
hydrogen
Prior art date
Application number
DK19286A
Other languages
Danish (da)
English (en)
Other versions
DK19286D0 (da
Inventor
James Stewart New
Jr Walter G Lobeck
Joseph P Yevich
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DK19286D0 publication Critical patent/DK19286D0/da
Publication of DK19286A publication Critical patent/DK19286A/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK19286A 1985-01-16 1986-01-15 Cykliske imidderivater af 2-(4-butylpiperazin-1-yl)-pyridiner DK19286A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/691,952 US4619930A (en) 1985-01-16 1985-01-16 Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use
US69195285 1985-01-16

Publications (2)

Publication Number Publication Date
DK19286D0 DK19286D0 (da) 1986-01-15
DK19286A true DK19286A (da) 1986-07-17

Family

ID=24778661

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19286A DK19286A (da) 1985-01-16 1986-01-15 Cykliske imidderivater af 2-(4-butylpiperazin-1-yl)-pyridiner

Country Status (29)

Country Link
US (1) US4619930A (zh)
JP (1) JPH0780873B2 (zh)
KR (1) KR900000366B1 (zh)
CN (1) CN1016691B (zh)
AT (1) AT391698B (zh)
AU (1) AU591473B2 (zh)
BE (1) BE904047A (zh)
CA (1) CA1284325C (zh)
CH (1) CH666269A5 (zh)
DE (1) DE3601143C2 (zh)
DK (1) DK19286A (zh)
EG (1) EG17759A (zh)
ES (2) ES8705869A1 (zh)
FI (1) FI90077C (zh)
FR (1) FR2580282B1 (zh)
GB (1) GB2191772B (zh)
HU (1) HU198202B (zh)
IE (1) IE58866B1 (zh)
IL (1) IL77577A (zh)
IT (1) IT1214497B (zh)
LU (1) LU86248A1 (zh)
NL (1) NL8600071A (zh)
NZ (1) NZ214790A (zh)
OA (1) OA08187A (zh)
PT (1) PT81843B (zh)
SE (1) SE466310B (zh)
SU (1) SU1521282A3 (zh)
YU (1) YU45757B (zh)
ZA (1) ZA859692B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4677104A (en) * 1985-05-06 1987-06-30 Bristol-Myers Company Antipsychotic fused-ring pyridinylpiperazine derivatives
US4812567A (en) * 1985-10-16 1989-03-14 American Home Products Corporation Polycyclic spiroimides with psychotropic activity
MX174210B (es) * 1987-02-17 1994-04-28 Pfizer Procedimiento para la preparacion de compuestos arilpiperazinil-alquilenfenil-p-heterociclicos
US4748240A (en) * 1987-04-03 1988-05-31 American Home Products Corporation Psychotropic bicyclic imides
ATE81123T1 (de) * 1987-11-20 1992-10-15 Hoechst Roussel Pharma 3-(4(1-substituierte-4-piperazinyl)butyl>-4thiazolidinone, verfahren zu deren herstellung und ihre anwendung als arzneimittel.
US4880930A (en) * 1987-11-30 1989-11-14 New James S Psychotropic acyclic amide derivatives
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US5116970A (en) * 1988-02-18 1992-05-26 New James S Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones
ZA918221B (en) * 1990-10-23 1992-06-24 Akzo Nv 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CN104230915B (zh) * 2014-08-29 2016-08-17 南京大学 含噻唑烷二酮的苯基哌嗪衍生物及其制备方法与用途
CN104513198A (zh) * 2014-11-29 2015-04-15 南京红太阳生物化学有限责任公司 一种2-氯烟酸的合成方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE759371A (fr) * 1969-11-24 1971-05-24 Bristol Myers Co Azaspirodecanediones heterocycliques et procedes pour leur preparation
US3976776A (en) * 1972-12-06 1976-08-24 Mead Johnson & Company Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones
AT330777B (de) * 1973-09-08 1976-07-26 Thomae Gmbh Dr K Verfahren zur herstellung von neuen isochinolinderivaten und deren salzen
US4305944A (en) * 1980-09-08 1981-12-15 Mead Johnson & Company N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4456756A (en) * 1981-08-03 1984-06-26 Mead Johnson & Company Spirothiazolidinyl piperazine derivatives
DE3135532A1 (de) * 1981-09-08 1983-03-24 NPL po Dvigateli s Vatrešno Gorene, Varna Brennkraftmaschine
US4361565A (en) * 1981-12-28 1982-11-30 Mead Johnson & Company 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines
JPS5976059A (ja) * 1982-10-21 1984-04-28 Sumitomo Chem Co Ltd 環状イミド誘導体及びその酸付加塩
JPS61238784A (ja) * 1985-04-17 1986-10-24 Sumitomo Seiyaku Kk コハク酸イミド誘導体及びその酸付加塩
DE3529872A1 (de) * 1985-08-21 1987-02-26 Kali Chemie Pharma Gmbh Neue tetraoxoverbindungen

Also Published As

Publication number Publication date
IE58866B1 (en) 1993-11-17
ES550829A0 (es) 1987-05-16
IT1214497B (it) 1990-01-18
ATA10086A (de) 1990-05-15
GB2191772B (en) 1990-05-23
US4619930A (en) 1986-10-28
GB8614686D0 (en) 1986-07-23
YU4186A (en) 1987-10-31
BE904047A (fr) 1986-07-15
HUT39743A (en) 1986-10-29
IE860125L (en) 1986-07-16
CH666269A5 (de) 1988-07-15
CA1284325C (en) 1991-05-21
DK19286D0 (da) 1986-01-15
FI860136A0 (fi) 1986-01-13
SE8600173L (sv) 1986-07-17
CN86100224A (zh) 1986-11-19
FI90077C (fi) 1993-12-27
FR2580282A1 (fr) 1986-10-17
KR900000366B1 (ko) 1990-01-25
FI860136A (fi) 1986-07-17
NL8600071A (nl) 1986-08-18
ES8705869A1 (es) 1987-05-16
PT81843B (pt) 1988-05-27
AT391698B (de) 1990-11-12
PT81843A (en) 1986-02-01
EG17759A (en) 1991-03-30
IL77577A (en) 1990-02-09
SU1521282A3 (ru) 1989-11-07
OA08187A (fr) 1987-10-30
NZ214790A (en) 1989-04-26
GB2191772A (en) 1987-12-23
ES8801822A1 (es) 1988-02-16
IT8619081A0 (it) 1986-01-15
FR2580282B1 (fr) 1992-10-16
ZA859692B (en) 1986-07-14
KR860005808A (ko) 1986-08-13
ES557390A0 (es) 1988-02-16
CN1016691B (zh) 1992-05-20
HU198202B (en) 1989-08-28
FI90077B (fi) 1993-09-15
AU5229486A (en) 1986-07-24
AU591473B2 (en) 1989-12-07
DE3601143C2 (de) 1994-05-11
SE466310B (sv) 1992-01-27
YU45757B (sh) 1992-07-20
DE3601143A1 (de) 1986-07-17
SE8600173D0 (sv) 1986-01-15
JPH0780873B2 (ja) 1995-08-30
JPS61167682A (ja) 1986-07-29
LU86248A1 (fr) 1986-08-04

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