DK175093B1 - DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf...... - Google Patents

DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf...... Download PDF

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Publication number
DK175093B1
DK175093B1 DK198604096A DK409686A DK175093B1 DK 175093 B1 DK175093 B1 DK 175093B1 DK 198604096 A DK198604096 A DK 198604096A DK 409686 A DK409686 A DK 409686A DK 175093 B1 DK175093 B1 DK 175093B1
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yeast
dna
hybrid
promoter
fragment
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DK198604096A
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Danish (da)
English (en)
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DK409686A (da
DK409686D0 (da
Inventor
Albert Hinnen
Bernd Meyhack
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Novartis Ag
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6456Plasminogen activators
    • C12N9/6459Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/65Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Led Devices (AREA)
  • Gyroscopes (AREA)
  • Graft Or Block Polymers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
DK198604096A 1985-08-29 1986-08-28 DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf...... DK175093B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858521496A GB8521496D0 (en) 1985-08-29 1985-08-29 Repressible yeast promoters
GB8521496 1985-08-29

Publications (3)

Publication Number Publication Date
DK409686D0 DK409686D0 (da) 1986-08-28
DK409686A DK409686A (da) 1987-03-01
DK175093B1 true DK175093B1 (da) 2004-05-24

Family

ID=10584428

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198604096A DK175093B1 (da) 1985-08-29 1986-08-28 DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf......

Country Status (22)

Country Link
US (1) US5436136A (ja)
EP (1) EP0213593B1 (ja)
JP (1) JPH07110233B2 (ja)
AT (1) ATE62510T1 (ja)
AU (1) AU599329B2 (ja)
CA (1) CA1318616C (ja)
DD (2) DD254212A5 (ja)
DE (1) DE3678647D1 (ja)
DK (1) DK175093B1 (ja)
ES (3) ES2001618A6 (ja)
FI (1) FI91280C (ja)
GB (1) GB8521496D0 (ja)
GR (1) GR862209B (ja)
HU (1) HU211207B (ja)
IE (1) IE58844B1 (ja)
IL (1) IL79837A (ja)
NO (1) NO175871C (ja)
NZ (1) NZ217388A (ja)
PH (1) PH24715A (ja)
PT (1) PT83273B (ja)
SU (1) SU1630616A3 (ja)
ZA (1) ZA866535B (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63501767A (ja) * 1985-11-13 1988-07-21 ゾマ、コーポレーション 短縮化されたホスホグリセリン酸キナ−ゼプロモ−タ−
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
MY101203A (en) * 1985-12-12 1991-08-17 Ucp Gen Pharma Ag Production of thrombin iinhibitors.
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
GB8907110D0 (en) * 1988-05-04 1989-05-10 Ciba Geigy Ag Improvements in the production of polypeptides
NO177065C (no) * 1988-09-26 1995-07-12 Labofina Sa Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
CA2090969C (en) * 1990-09-04 2001-08-21 Russell Arthur Brierley Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
EP0578746B1 (en) * 1991-04-01 2002-07-03 Merck & Co., Inc. GENES WHICH INFLUENCE $i(PICHIA) PROTEOLYTIC ACTIVITY, AND USES THEREFOR
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
US6159705A (en) * 1996-09-24 2000-12-12 Cadus Pharmaceutical Corporation Recombinant yeast cells for identifying receptor effectors
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en) 1999-12-10 2005-05-10 The Salk Institute Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
EP2571991A1 (en) 2010-05-20 2013-03-27 Evolva SA Method of producing isoprenoid compounds in yeast
AU2021260878A1 (en) 2020-04-20 2022-11-17 Vestaron Corporation Proteolytically stable U1-agatoxin-Ta1b variant polypeptides for pest control
AU2021265277A1 (en) 2020-05-01 2022-12-08 Vestaron Corporation Insecticidal combinations
WO2022212777A2 (en) 2021-04-01 2022-10-06 Vestaron Corporation Av3 mutant polypeptides for pest control
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method
WO2023225555A1 (en) 2022-05-18 2023-11-23 Vestaron Corporation Pesticidal actx peptide variants
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
WO2024026406A2 (en) 2022-07-29 2024-02-01 Vestaron Corporation Next Generation ACTX Peptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
ATE78293T1 (de) * 1983-05-27 1992-08-15 Texas A & M Univ Sys Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors.
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
PH22337A (en) * 1983-11-21 1988-08-12 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast
EP0164566A3 (de) * 1984-05-11 1986-10-29 LGA Gastechnik GmbH Sicherheitseinrichtung für Flüssiggastanks
EP0480480A3 (en) * 1984-05-11 1992-06-10 Chiron Corporation Enhanced yeast transcription employing hybrid promoter region constructs
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen

Also Published As

Publication number Publication date
JPH07110233B2 (ja) 1995-11-29
ES2001618A6 (es) 1988-06-01
IE862307L (en) 1987-02-28
DK409686A (da) 1987-03-01
US5436136A (en) 1995-07-25
IL79837A (en) 1992-06-21
DD254212A5 (de) 1988-02-17
DD267739A5 (de) 1989-05-10
EP0213593A1 (en) 1987-03-11
PT83273B (pt) 1989-05-12
NZ217388A (en) 1989-02-24
ATE62510T1 (de) 1991-04-15
HUT42525A (en) 1987-07-28
IL79837A0 (en) 1986-11-30
ZA866535B (en) 1987-04-29
FI91280B (fi) 1994-02-28
JPS6251995A (ja) 1987-03-06
PH24715A (en) 1990-10-01
ES2006383A6 (es) 1989-04-16
NO175871B (ja) 1994-09-12
ES2006382A6 (es) 1989-04-16
FI863430A (fi) 1987-03-01
PT83273A (en) 1986-09-01
NO863458L (no) 1987-03-02
CA1318616C (en) 1993-06-01
AU599329B2 (en) 1990-07-19
GB8521496D0 (en) 1985-10-02
IE58844B1 (en) 1993-11-17
NO175871C (no) 1994-12-21
SU1630616A3 (ru) 1991-02-23
DK409686D0 (da) 1986-08-28
GR862209B (en) 1986-12-31
EP0213593B1 (en) 1991-04-10
HU211207B (en) 1995-11-28
DE3678647D1 (en) 1991-05-16
NO863458D0 (no) 1986-08-28
FI91280C (fi) 1994-06-10
AU6203286A (en) 1987-03-05
FI863430A0 (fi) 1986-08-25

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