NO175871C - Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær - Google Patents

Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær

Info

Publication number
NO175871C
NO175871C NO863458A NO863458A NO175871C NO 175871 C NO175871 C NO 175871C NO 863458 A NO863458 A NO 863458A NO 863458 A NO863458 A NO 863458A NO 175871 C NO175871 C NO 175871C
Authority
NO
Norway
Prior art keywords
yeast
host
preparing
yeast hybrid
polypeptide heterologous
Prior art date
Application number
NO863458A
Other languages
English (en)
Norwegian (no)
Other versions
NO863458L (no
NO175871B (ja
NO863458D0 (no
Inventor
Albert Hinnen
Bernd Meyhack
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO863458D0 publication Critical patent/NO863458D0/no
Publication of NO863458L publication Critical patent/NO863458L/no
Publication of NO175871B publication Critical patent/NO175871B/no
Publication of NO175871C publication Critical patent/NO175871C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Graft Or Block Polymers (AREA)
  • Led Devices (AREA)
  • Gyroscopes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
NO863458A 1985-08-29 1986-08-28 Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær NO175871C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858521496A GB8521496D0 (en) 1985-08-29 1985-08-29 Repressible yeast promoters

Publications (4)

Publication Number Publication Date
NO863458D0 NO863458D0 (no) 1986-08-28
NO863458L NO863458L (no) 1987-03-02
NO175871B NO175871B (ja) 1994-09-12
NO175871C true NO175871C (no) 1994-12-21

Family

ID=10584428

Family Applications (1)

Application Number Title Priority Date Filing Date
NO863458A NO175871C (no) 1985-08-29 1986-08-28 Gjærhybridpromotor, gjærhybridvektor, Saccharomyces spec.-vert, samt fremgangsmåte for fremstilling av et polypeptid heterologt med gjær

Country Status (22)

Country Link
US (1) US5436136A (ja)
EP (1) EP0213593B1 (ja)
JP (1) JPH07110233B2 (ja)
AT (1) ATE62510T1 (ja)
AU (1) AU599329B2 (ja)
CA (1) CA1318616C (ja)
DD (2) DD254212A5 (ja)
DE (1) DE3678647D1 (ja)
DK (1) DK175093B1 (ja)
ES (3) ES2001618A6 (ja)
FI (1) FI91280C (ja)
GB (1) GB8521496D0 (ja)
GR (1) GR862209B (ja)
HU (1) HU211207B (ja)
IE (1) IE58844B1 (ja)
IL (1) IL79837A (ja)
NO (1) NO175871C (ja)
NZ (1) NZ217388A (ja)
PH (1) PH24715A (ja)
PT (1) PT83273B (ja)
SU (1) SU1630616A3 (ja)
ZA (1) ZA866535B (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU621277B2 (en) * 1985-11-13 1992-03-12 Xoma Corporation Shortened phosphoglycerate kinase promoter
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
MY101203A (en) * 1985-12-12 1991-08-17 Ucp Gen Pharma Ag Production of thrombin iinhibitors.
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
GB8907110D0 (en) * 1988-05-04 1989-05-10 Ciba Geigy Ag Improvements in the production of polypeptides
NO177065C (no) * 1988-09-26 1995-07-12 Labofina Sa Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
WO1992004363A1 (en) * 1990-09-04 1992-03-19 The Salk Institute Biotechnology/Industrial Associates, Inc. Production of insulin-like growth factor-1 in methylotrophic yeast cells
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
CA2105064A1 (en) * 1991-04-01 1992-10-02 Martin Anthony Gleeson Genes which influence pichia proteolytic activity, and uses therefor
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
ATE284972T1 (de) * 1996-09-24 2005-01-15 Cadus Pharmaceutical Corp Verfahren und zusammensetzungen für die identifizierung von receptor effectoren
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en) 1999-12-10 2005-05-10 The Salk Institute Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
WO2011146833A1 (en) 2010-05-20 2011-11-24 Evolva Inc. Method of producing isoprenoid compounds in yeast
CN116018350A (zh) 2020-04-20 2023-04-25 韦斯塔隆公司 用于有害生物防治的蛋白水解稳定的U1-漏斗网蛛毒素-Ta1b变体多肽
KR20230005929A (ko) 2020-05-01 2023-01-10 베스타론 코포레이션 살충 조합물
AR125258A1 (es) 2021-04-01 2023-06-28 Vestaron Corp Polipéptidos con mutaciones de av3 para el control de plagas
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method
WO2023225555A1 (en) 2022-05-18 2023-11-23 Vestaron Corporation Pesticidal actx peptide variants
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
WO2024026406A2 (en) 2022-07-29 2024-02-01 Vestaron Corporation Next Generation ACTX Peptides

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
IE58011B1 (en) * 1983-05-27 1993-06-16 Texas A & M Univ Sys Method for producing a recombinant baculovirus expression vector
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
EP0143081B1 (en) * 1983-11-21 1989-08-23 Ciba-Geigy Ag Synthesis of tissue plasminogen activator(tpa) by yeast
ATE102250T1 (de) * 1984-05-11 1994-03-15 Chiron Corp Erhoehte hefetranskription unter verwendung einer hybridkonstruktion der promotorregion.
EP0164566A3 (de) * 1984-05-11 1986-10-29 LGA Gastechnik GmbH Sicherheitseinrichtung für Flüssiggastanks
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen

Also Published As

Publication number Publication date
AU599329B2 (en) 1990-07-19
IE58844B1 (en) 1993-11-17
ES2006382A6 (es) 1989-04-16
EP0213593B1 (en) 1991-04-10
US5436136A (en) 1995-07-25
GB8521496D0 (en) 1985-10-02
PH24715A (en) 1990-10-01
IL79837A (en) 1992-06-21
NZ217388A (en) 1989-02-24
ZA866535B (en) 1987-04-29
DD254212A5 (de) 1988-02-17
PT83273A (en) 1986-09-01
PT83273B (pt) 1989-05-12
DK409686A (da) 1987-03-01
HU211207B (en) 1995-11-28
FI863430A0 (fi) 1986-08-25
GR862209B (en) 1986-12-31
ES2006383A6 (es) 1989-04-16
NO863458L (no) 1987-03-02
DK175093B1 (da) 2004-05-24
FI91280C (fi) 1994-06-10
FI863430A (fi) 1987-03-01
ATE62510T1 (de) 1991-04-15
IE862307L (en) 1987-02-28
JPS6251995A (ja) 1987-03-06
DD267739A5 (de) 1989-05-10
ES2001618A6 (es) 1988-06-01
NO175871B (ja) 1994-09-12
FI91280B (fi) 1994-02-28
AU6203286A (en) 1987-03-05
CA1318616C (en) 1993-06-01
DK409686D0 (da) 1986-08-28
DE3678647D1 (en) 1991-05-16
EP0213593A1 (en) 1987-03-11
HUT42525A (en) 1987-07-28
JPH07110233B2 (ja) 1995-11-29
NO863458D0 (no) 1986-08-28
SU1630616A3 (ru) 1991-02-23
IL79837A0 (en) 1986-11-30

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