DK409686A - Repressible gaerpromotorer - Google Patents

Repressible gaerpromotorer Download PDF

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Publication number
DK409686A
DK409686A DK409686A DK409686A DK409686A DK 409686 A DK409686 A DK 409686A DK 409686 A DK409686 A DK 409686A DK 409686 A DK409686 A DK 409686A DK 409686 A DK409686 A DK 409686A
Authority
DK
Denmark
Prior art keywords
yeast
promoters
repressible
yellow
hybrid promoters
Prior art date
Application number
DK409686A
Other languages
English (en)
Other versions
DK175093B1 (da
DK409686D0 (da
Inventor
Albert Hinnen
Bernd Meyhack
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK409686D0 publication Critical patent/DK409686D0/da
Publication of DK409686A publication Critical patent/DK409686A/da
Application granted granted Critical
Publication of DK175093B1 publication Critical patent/DK175093B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Gyroscopes (AREA)
  • Led Devices (AREA)
  • Graft Or Block Polymers (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
DK198604096A 1985-08-29 1986-08-28 DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf...... DK175093B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8521496 1985-08-29
GB858521496A GB8521496D0 (en) 1985-08-29 1985-08-29 Repressible yeast promoters

Publications (3)

Publication Number Publication Date
DK409686D0 DK409686D0 (da) 1986-08-28
DK409686A true DK409686A (da) 1987-03-01
DK175093B1 DK175093B1 (da) 2004-05-24

Family

ID=10584428

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198604096A DK175093B1 (da) 1985-08-29 1986-08-28 DNA-fragment, fremgangsmåde til fremstilling deraf, gærhybridpromotor, indeholdende DNA-fragmentet, fremgangsmåde til fremstilling deraf......

Country Status (22)

Country Link
US (1) US5436136A (da)
EP (1) EP0213593B1 (da)
JP (1) JPH07110233B2 (da)
AT (1) ATE62510T1 (da)
AU (1) AU599329B2 (da)
CA (1) CA1318616C (da)
DD (2) DD254212A5 (da)
DE (1) DE3678647D1 (da)
DK (1) DK175093B1 (da)
ES (3) ES2001618A6 (da)
FI (1) FI91280C (da)
GB (1) GB8521496D0 (da)
GR (1) GR862209B (da)
HU (1) HU211207B (da)
IE (1) IE58844B1 (da)
IL (1) IL79837A (da)
NO (1) NO175871C (da)
NZ (1) NZ217388A (da)
PH (1) PH24715A (da)
PT (1) PT83273B (da)
SU (1) SU1630616A3 (da)
ZA (1) ZA866535B (da)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987003008A1 (en) * 1985-11-13 1987-05-21 International Genetic Engineering, Inc. Shortened phosphoglycerate kinase promoter
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
MY101203A (en) * 1985-12-12 1991-08-17 Ucp Gen Pharma Ag Production of thrombin iinhibitors.
GB8620926D0 (en) * 1986-08-29 1986-10-08 Delta Biotechnology Ltd Yeast promoter
GB8907110D0 (en) * 1988-05-04 1989-05-10 Ciba Geigy Ag Improvements in the production of polypeptides
NO177065C (no) * 1988-09-26 1995-07-12 Labofina Sa Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym
JPH06500470A (ja) * 1990-09-04 1994-01-20 メルク　エンド　カンパニー　インコーポレーテッド メチロトローフ酵母細胞におけるインスリン様成長因子の産生
US5612198A (en) * 1990-09-04 1997-03-18 The Salk Institute Production of insulin-like growth factor-1 in methylotrophic yeast cells
CA2105064A1 (en) * 1991-04-01 1992-10-02 Martin Anthony Gleeson Genes which influence pichia proteolytic activity, and uses therefor
US5674728A (en) * 1993-11-03 1997-10-07 Novartis Corporation Aspergillus niger vacuolar aspartyl protease
JPH08173170A (ja) * 1994-05-25 1996-07-09 Kirin Brewery Co Ltd キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現
WO1998013513A2 (en) * 1996-09-24 1998-04-02 Cadus Pharmaceutical Corporation Methods and compositions for identifying receptor effectors
US6265186B1 (en) 1997-04-11 2001-07-24 Dsm N.V. Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces
US6890730B1 (en) 1999-12-10 2005-05-10 The Salk Institute Sequence and method for increasing protein expression in cellular expression systems
US8008459B2 (en) * 2001-01-25 2011-08-30 Evolva Sa Concatemers of differentially expressed multiple genes
US9476082B2 (en) 2010-05-20 2016-10-25 Evolva Sa Method of producing isoprenoid compounds in yeast
AU2013229777B2 (en) 2012-03-09 2017-10-26 Vestaron Corporation Toxic peptide production, peptide expression in plants and combinations of cysteine rich peptides
PT4139334T (pt) 2020-04-20 2024-11-27 Vestaron Corp Polipéptidos variantes de u1-agatoxina-ta1b proteoliticamente estáveis para controlo de pragas
TW202205956A (zh) 2020-05-01 2022-02-16 美商韋斯塔隆公司 殺蟲組合
IL307293A (en) 2021-04-01 2023-11-01 Vestaron Corp Av3 mutant polypeptides for pest control
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method
EP4526330A1 (en) 2022-05-18 2025-03-26 Vestaron Corporation Pesticidal actx peptide variants
WO2023245100A1 (en) 2022-06-17 2023-12-21 Vestaron Corporation Antimicrobial ncr13 variant peptides
WO2024026406A2 (en) 2022-07-29 2024-02-01 Vestaron Corporation Next Generation ACTX Peptides
WO2024259306A2 (en) 2023-06-16 2024-12-19 Vestaron Corporation Pvd1 variant polypeptides for pest control
WO2025226701A1 (en) 2024-04-23 2025-10-30 Vestaron Corporation Proteolytically stable u1-agatoxin-ta1b variant polypeptides for pest control

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
AU577259B2 (en) * 1982-08-13 1988-09-22 Zymogenetics Inc. Glycolytic promters for regulated protein expression protease inhibitor
US4876197A (en) * 1983-02-22 1989-10-24 Chiron Corporation Eukaryotic regulatable transcription
NZ207926A (en) * 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
EP0127839B1 (en) * 1983-05-27 1992-07-15 THE TEXAS A&M UNIVERSITY SYSTEM Method for producing a recombinant baculovirus expression vector
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
EP0143081B1 (en) * 1983-11-21 1989-08-23 Ciba-Geigy Ag Synthesis of tissue plasminogen activator(tpa) by yeast
EP0164566A3 (de) * 1984-05-11 1986-10-29 LGA Gastechnik GmbH Sicherheitseinrichtung für Flüssiggastanks
EP0164556B1 (en) * 1984-05-11 1994-03-02 Chiron Corporation Enhanced yeast transcription employing hybrid promoter region constructs
US4895800A (en) * 1985-11-26 1990-01-23 Phillips Petroleum Company Yeast production of hepatitis B surface antigen

Also Published As

Publication number Publication date
EP0213593A1 (en) 1987-03-11
AU599329B2 (en) 1990-07-19
ATE62510T1 (de) 1991-04-15
DK175093B1 (da) 2004-05-24
JPS6251995A (ja) 1987-03-06
IE862307L (en) 1987-02-28
GR862209B (en) 1986-12-31
US5436136A (en) 1995-07-25
FI91280B (fi) 1994-02-28
FI863430A0 (fi) 1986-08-25
FI91280C (fi) 1994-06-10
HUT42525A (en) 1987-07-28
ES2006382A6 (es) 1989-04-16
ES2001618A6 (es) 1988-06-01
NO863458D0 (no) 1986-08-28
NO175871C (no) 1994-12-21
DK409686D0 (da) 1986-08-28
ES2006383A6 (es) 1989-04-16
SU1630616A3 (ru) 1991-02-23
PT83273B (pt) 1989-05-12
PT83273A (en) 1986-09-01
CA1318616C (en) 1993-06-01
NZ217388A (en) 1989-02-24
HU211207B (en) 1995-11-28
GB8521496D0 (en) 1985-10-02
FI863430L (fi) 1987-03-01
DE3678647D1 (en) 1991-05-16
IE58844B1 (en) 1993-11-17
EP0213593B1 (en) 1991-04-10
AU6203286A (en) 1987-03-05
ZA866535B (en) 1987-04-29
JPH07110233B2 (ja) 1995-11-29
DD254212A5 (de) 1988-02-17
DD267739A5 (de) 1989-05-10
PH24715A (en) 1990-10-01
IL79837A0 (en) 1986-11-30
NO175871B (da) 1994-09-12
IL79837A (en) 1992-06-21
NO863458L (no) 1987-03-02

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