ES2001618A6 - Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura. - Google Patents
Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura.Info
- Publication number
- ES2001618A6 ES2001618A6 ES8601490A ES8601490A ES2001618A6 ES 2001618 A6 ES2001618 A6 ES 2001618A6 ES 8601490 A ES8601490 A ES 8601490A ES 8601490 A ES8601490 A ES 8601490A ES 2001618 A6 ES2001618 A6 ES 2001618A6
- Authority
- ES
- Spain
- Prior art keywords
- yeast
- yeast promoters
- hybrid promoters
- repressible
- repressible yeast
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 6
- 108091026890 Coding region Proteins 0.000 abstract 1
- 101150012394 PHO5 gene Proteins 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000035897 transcription Effects 0.000 abstract 1
- 238000013518 transcription Methods 0.000 abstract 1
- 238000011144 upstream manufacturing Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Tropical Medicine & Parasitology (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Alcoholic Beverages (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Gyroscopes (AREA)
- Led Devices (AREA)
- Graft Or Block Polymers (AREA)
- Enzymes And Modification Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE PROMOTORES DE LEVADURA REPRESIBLES CONTENIENDO PUNTOS DE ACTIVACION AGUA ARRIBA DEL GEN PHO5 DE LEVADURA, CARACTERIZADO PORQUE COMPRENDE LIGAR UN ELEMENTO PROMOTOR AGUAS ARRIBA (5K) CONTENIENDO UN PUNTO OPUNTOS DE ACTIVACION AGUAS ARRIBA DEL GEN PHO5 DE LEVADURA A UN ELEMENTO PROMOTOR AGUAS ABAJO (3K) DE UN GEN DE LEVADURA DISTINTO DEL GEN PHO5 INCLUYENDO UNA CAJA TATA FUNCIONAL Y QUE FINALIZA CERCA DEL CODON INICIADOR DE LA TRADUCCION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858521496A GB8521496D0 (en) | 1985-08-29 | 1985-08-29 | Repressible yeast promoters |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2001618A6 true ES2001618A6 (es) | 1988-06-01 |
Family
ID=10584428
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8601490A Expired ES2001618A6 (es) | 1985-08-29 | 1986-08-29 | Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura. |
ES8800794A Expired ES2006382A6 (es) | 1985-08-29 | 1988-03-16 | Procedimiento para la preparacion de un polipeptido mediante levadura que contiene un promotor hibrido con los puntos de activacion aguas arriba del gen pho5 de levadura. |
ES8800795A Expired ES2006383A6 (es) | 1985-08-29 | 1988-03-16 | Procedimiento para la preparacion de vectores hibridos de levadura comprendiendo promotores de levadura represibles con los lugares de actuacion aguas arriba del gen ph05 de levadura. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES8800794A Expired ES2006382A6 (es) | 1985-08-29 | 1988-03-16 | Procedimiento para la preparacion de un polipeptido mediante levadura que contiene un promotor hibrido con los puntos de activacion aguas arriba del gen pho5 de levadura. |
ES8800795A Expired ES2006383A6 (es) | 1985-08-29 | 1988-03-16 | Procedimiento para la preparacion de vectores hibridos de levadura comprendiendo promotores de levadura represibles con los lugares de actuacion aguas arriba del gen ph05 de levadura. |
Country Status (22)
Country | Link |
---|---|
US (1) | US5436136A (es) |
EP (1) | EP0213593B1 (es) |
JP (1) | JPH07110233B2 (es) |
AT (1) | ATE62510T1 (es) |
AU (1) | AU599329B2 (es) |
CA (1) | CA1318616C (es) |
DD (2) | DD254212A5 (es) |
DE (1) | DE3678647D1 (es) |
DK (1) | DK175093B1 (es) |
ES (3) | ES2001618A6 (es) |
FI (1) | FI91280C (es) |
GB (1) | GB8521496D0 (es) |
GR (1) | GR862209B (es) |
HU (1) | HU211207B (es) |
IE (1) | IE58844B1 (es) |
IL (1) | IL79837A (es) |
NO (1) | NO175871C (es) |
NZ (1) | NZ217388A (es) |
PH (1) | PH24715A (es) |
PT (1) | PT83273B (es) |
SU (1) | SU1630616A3 (es) |
ZA (1) | ZA866535B (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU621277B2 (en) * | 1985-11-13 | 1992-03-12 | Xoma Corporation | Shortened phosphoglycerate kinase promoter |
GB8530631D0 (en) | 1985-12-12 | 1986-01-22 | Ciba Geigy Ag | Thrombin inhibitors |
MY101203A (en) * | 1985-12-12 | 1991-08-17 | Ucp Gen Pharma Ag | Production of thrombin iinhibitors. |
GB8620926D0 (en) * | 1986-08-29 | 1986-10-08 | Delta Biotechnology Ltd | Yeast promoter |
GB8907110D0 (en) * | 1988-05-04 | 1989-05-10 | Ciba Geigy Ag | Improvements in the production of polypeptides |
NO177065C (no) * | 1988-09-26 | 1995-07-12 | Labofina Sa | Framgangsmåte for framstilling av enzymatisk aktivt humant lysozym |
JPH06500470A (ja) * | 1990-09-04 | 1994-01-20 | メルク エンド カンパニー インコーポレーテッド | メチロトローフ酵母細胞におけるインスリン様成長因子の産生 |
US5612198A (en) * | 1990-09-04 | 1997-03-18 | The Salk Institute | Production of insulin-like growth factor-1 in methylotrophic yeast cells |
ATE220105T1 (de) * | 1991-04-01 | 2002-07-15 | Merck & Co Inc | Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung |
US5674728A (en) * | 1993-11-03 | 1997-10-07 | Novartis Corporation | Aspergillus niger vacuolar aspartyl protease |
JPH08173170A (ja) * | 1994-05-25 | 1996-07-09 | Kirin Brewery Co Ltd | キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現 |
ATE284972T1 (de) * | 1996-09-24 | 2005-01-15 | Cadus Pharmaceutical Corp | Verfahren und zusammensetzungen für die identifizierung von receptor effectoren |
US6265186B1 (en) | 1997-04-11 | 2001-07-24 | Dsm N.V. | Yeast cells comprising at least two copies of a desired gene integrated into the chromosomal genome at more than one non-ribosomal RNA encoding domain, particularly with Kluyveromyces |
US6890730B1 (en) | 1999-12-10 | 2005-05-10 | The Salk Institute | Sequence and method for increasing protein expression in cellular expression systems |
US8008459B2 (en) * | 2001-01-25 | 2011-08-30 | Evolva Sa | Concatemers of differentially expressed multiple genes |
EP2571991A1 (en) | 2010-05-20 | 2013-03-27 | Evolva SA | Method of producing isoprenoid compounds in yeast |
PE20231212A1 (es) | 2020-04-20 | 2023-08-17 | Vestaron Corp | Polipeptidos variantes proteoliticamente estables de u1-agatoxina-ta1b para el control de plagas |
TW202205956A (zh) | 2020-05-01 | 2022-02-16 | 美商韋斯塔隆公司 | 殺蟲組合 |
CA3215602A1 (en) | 2021-04-01 | 2022-10-06 | Vestaron Corporation | Av3 mutant polypeptides for pest control |
WO2023122805A1 (en) | 2021-12-20 | 2023-06-29 | Vestaron Corporation | Sorbitol driven selection pressure method |
WO2023225555A1 (en) | 2022-05-18 | 2023-11-23 | Vestaron Corporation | Pesticidal actx peptide variants |
WO2023245100A1 (en) | 2022-06-17 | 2023-12-21 | Vestaron Corporation | Antimicrobial ncr13 variant peptides |
WO2024026406A2 (en) | 2022-07-29 | 2024-02-01 | Vestaron Corporation | Next Generation ACTX Peptides |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2125047B (en) * | 1982-08-09 | 1986-02-19 | Ciba Geigy Ag | Yeast hybrid vectors and their use for the production of polypeptides |
AU577259B2 (en) * | 1982-08-13 | 1988-09-22 | Zymogenetics Inc. | Glycolytic promters for regulated protein expression protease inhibitor |
US4876197A (en) * | 1983-02-22 | 1989-10-24 | Chiron Corporation | Eukaryotic regulatable transcription |
NZ207926A (en) * | 1983-04-25 | 1988-04-29 | Genentech Inc | Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast |
DE3485810T2 (de) * | 1983-05-27 | 1992-12-10 | Texas A & M University Syst | Verfahren zur herstellung eines rekombinanten baculovirus-expressionsvektors. |
GB8314961D0 (en) * | 1983-05-31 | 1983-07-06 | Kingsman A J | Dna sequence |
DE3479520D1 (en) * | 1983-11-21 | 1989-09-28 | Ciba Geigy Ag | Synthesis of tissue plasminogen activator(tpa) by yeast |
EP0164556B1 (en) * | 1984-05-11 | 1994-03-02 | Chiron Corporation | Enhanced yeast transcription employing hybrid promoter region constructs |
EP0164566A3 (de) * | 1984-05-11 | 1986-10-29 | LGA Gastechnik GmbH | Sicherheitseinrichtung für Flüssiggastanks |
US4895800A (en) * | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
-
1985
- 1985-08-29 GB GB858521496A patent/GB8521496D0/en active Pending
-
1986
- 1986-08-25 FI FI863430A patent/FI91280C/fi not_active IP Right Cessation
- 1986-08-25 IL IL79837A patent/IL79837A/xx not_active IP Right Cessation
- 1986-08-26 AT AT86111820T patent/ATE62510T1/de not_active IP Right Cessation
- 1986-08-26 DE DE8686111820T patent/DE3678647D1/de not_active Expired - Lifetime
- 1986-08-26 EP EP86111820A patent/EP0213593B1/en not_active Expired - Lifetime
- 1986-08-27 GR GR862209A patent/GR862209B/el unknown
- 1986-08-27 DD DD29389486A patent/DD254212A5/de not_active IP Right Cessation
- 1986-08-27 CA CA000516879A patent/CA1318616C/en not_active Expired - Lifetime
- 1986-08-27 DD DD31325586A patent/DD267739A5/de unknown
- 1986-08-28 PT PT83273A patent/PT83273B/pt unknown
- 1986-08-28 NZ NZ217388A patent/NZ217388A/xx unknown
- 1986-08-28 PH PH34192A patent/PH24715A/en unknown
- 1986-08-28 NO NO863458A patent/NO175871C/no not_active IP Right Cessation
- 1986-08-28 ZA ZA866535A patent/ZA866535B/xx unknown
- 1986-08-28 IE IE230786A patent/IE58844B1/en not_active IP Right Cessation
- 1986-08-28 HU HU863720A patent/HU211207B/hu unknown
- 1986-08-28 DK DK198604096A patent/DK175093B1/da not_active IP Right Cessation
- 1986-08-28 AU AU62032/86A patent/AU599329B2/en not_active Expired
- 1986-08-28 SU SU864028035A patent/SU1630616A3/ru active
- 1986-08-29 ES ES8601490A patent/ES2001618A6/es not_active Expired
- 1986-08-29 JP JP61201924A patent/JPH07110233B2/ja not_active Expired - Lifetime
-
1988
- 1988-03-16 ES ES8800794A patent/ES2006382A6/es not_active Expired
- 1988-03-16 ES ES8800795A patent/ES2006383A6/es not_active Expired
-
1991
- 1991-12-20 US US07/811,898 patent/US5436136A/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2001618A6 (es) | Procedimiento para la preparacion de promotores de levadura represibles conteniendo puntos de actividad agua arriba del gen phos de levadura. | |
UA27706C2 (uk) | Спосіб одержання гетерологічного поліпептиду | |
NZ188838A (en) | Dna coding for microbial expression of mammalian polypeptide recombinant microbial cloning vehicle | |
AU590733B2 (en) | Aspergillus niger transformation system | |
ES8604308A1 (es) | Un vector para producir un producto genetico por celulas de insectos | |
AU551251B2 (en) | Recombinant dna; chymosin production | |
NO178035C (no) | Ekspressjonsvektor, gjærcelle som er i stand til å utskille desulfatohirudin samt fremgangsmåte for fremstilling av et terapeutisk aktivt desulfatohirudin | |
JPS6485098A (en) | Glycoprotein and production thereof | |
ES2056753A6 (es) | Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos. | |
MY103358A (en) | Process for the production of protiens. | |
IL82207A (en) | Production of peptides,recombinant plasmid used therefor cntaining two sv40 promoters and myeloma cells transformed therewith | |
DE3479816D1 (en) | A promotor and use thereof | |
ES8606402A1 (es) | Un procedimiento para preparar una molecula de adn recom- biante | |
AR245956A1 (es) | Vector de adn, cepa bacteriana que lo contiene y metodo para modificar geneticamente una celula vegetal | |
ES8800342A1 (es) | Procedimiento para preparar un vector de levadura de copias multiples,estables y recombinante | |
EP0165759A3 (en) | Mammalian promotors useful in yeast expression | |
KR960001818B1 (en) | Method for producing hirudin | |
MY108667A (en) | Recombinant gene coding for human alpha interferon and expression vector thereof, etc. | |
JPS5717293A (en) | Remote like concentrated station stand alone system | |
AU2889277A (en) | Method of supplying extra oxygen to yeast cultures |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1A | Transfer granted | ||
FD1A | Patent lapsed |
Effective date: 20060830 |