ES2056753A6 - Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos. - Google Patents

Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.

Info

Publication number
ES2056753A6
ES2056753A6 ES09050005A ES9050005A ES2056753A6 ES 2056753 A6 ES2056753 A6 ES 2056753A6 ES 09050005 A ES09050005 A ES 09050005A ES 9050005 A ES9050005 A ES 9050005A ES 2056753 A6 ES2056753 A6 ES 2056753A6
Authority
ES
Spain
Prior art keywords
polypeptide
chemotactic factor
factor activity
human monocyte
monocyte chemotactic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES09050005A
Other languages
English (en)
Inventor
Yasuji Furutani
Toshikazu Fukui
Yamagishi Junichi
Yamada Masaaki
Kouji Matsushima
Joost Oppenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Commerce
Original Assignee
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2056753(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP64000065A external-priority patent/JP2893112B2/ja
Priority claimed from JP1026438A external-priority patent/JP2992640B2/ja
Application filed by US Department of Commerce filed Critical US Department of Commerce
Publication of ES2056753A6 publication Critical patent/ES2056753A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PRODUCCION DE UN POLIPEPTIDO QUE TIENE ACTIVIDAD DE FACTOR QUEMOTACTICO DE MONOCITOS HUMANOS. COMPRENDE CULTIVAR UN HUESPED MICROBIANO TRANSFORMADO POR UN VECTOR DE EXPRESION QUE CONTIENE UNA SECUENCIA DE AMINO-ACIDOS REPRESENTADA POR LA SIGUIENTE FORMULA (I) O SU PORCION PRINCIPAL: GLN PRO ASP ALA ILE ASN ALA PRO VAL THR CYS CYS TYR ASN PHE THR ASN ARG LYS ILE SER VAL GLN ARG LEU ALA SER TYR ARG ARG ILE THR SER SER LYS CYS PRO LYS GLU ALA VAL ILE PHE LYS THR ILE VAL ALA LYS GLU ILE CYS X ASP PRO LYS GLN LYS TRP VAL GLN ASP SER MET ASP HIS LEU ASP LYS GLN THR GLN THR PRO LYS THR. EN DONDE X SIGNIFICA ALA O THR.
ES09050005A 1989-01-01 1990-01-02 Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos. Expired - Fee Related ES2056753A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP64000065A JP2893112B2 (ja) 1989-01-01 1989-01-01 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするｄｎａ
JP1026438A JP2992640B2 (ja) 1989-02-03 1989-02-03 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするｄｎａ並びにそれらの製法

Publications (1)

Publication Number Publication Date
ES2056753A6 true ES2056753A6 (es) 1994-10-01

Family

ID=26332976

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90901711T Expired - Lifetime ES2104600T3 (es) 1989-01-01 1990-01-02 Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido.
ES09050005A Expired - Fee Related ES2056753A6 (es) 1989-01-01 1990-01-02 Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES90901711T Expired - Lifetime ES2104600T3 (es) 1989-01-01 1990-01-02 Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido.

Country Status (10)

Country Link
EP (1) EP0452391B1 (es)
JP (1) JPH04501961A (es)
AT (1) ATE155526T1 (es)
AU (1) AU642399B2 (es)
CA (1) CA2006969C (es)
DE (1) DE69031071T2 (es)
DK (1) DK0452391T3 (es)
ES (2) ES2104600T3 (es)
IL (1) IL92938A (es)
WO (1) WO1990007863A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92937A0 (en) 1989-01-31 1990-09-17 Us Health Human derived monocyte attracting protein,pharmaceutical compositions comprising it and dna encoding it
US6767535B1 (en) 1989-05-12 2004-07-27 Dana-Farber Cancer Institute, Inc. Suppressing tumor formation using cells expressing JE/monocyte chemoattractant protein-1
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
DE69133159D1 (de) * 1990-09-05 2003-01-02 Heart Res Inst Ltd Chemotaktische faktoren
US6001649A (en) * 1990-11-29 1999-12-14 Societe Anonyme: Elf Sanofi Chemokine NC28 (monocyte chemotactic protein-3, MCP-3) polypeptides and their recombinant production
WO1992019737A1 (en) * 1991-05-09 1992-11-12 Dainippon Pharmaceutical Co., Ltd. Process for producing a monocyte chemotactic factor polypeptide and a strain for the production thereof
JPH0782169A (ja) * 1993-09-13 1995-03-28 Toray Ind Inc 創傷治療剤
US7265201B1 (en) 1995-06-23 2007-09-04 Millennium Pharmaceuticals, Inc. Human chemotactic cytokine
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
WO2007021807A1 (en) 2005-08-12 2007-02-22 Schering Corporation Mcp1 fusions
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants

Also Published As

Publication number Publication date
AU642399B2 (en) 1993-10-21
DE69031071D1 (de) 1997-08-21
IL92938A (en) 1998-08-16
EP0452391B1 (en) 1997-07-16
ATE155526T1 (de) 1997-08-15
DK0452391T3 (da) 1997-10-20
ES2104600T3 (es) 1997-10-16
WO1990007863A1 (en) 1990-07-26
EP0452391A4 (en) 1992-06-03
AU4845090A (en) 1990-08-13
CA2006969C (en) 2000-03-14
DE69031071T2 (de) 1998-02-05
EP0452391A1 (en) 1991-10-23
JPH04501961A (ja) 1992-04-09
IL92938A0 (en) 1990-09-17
CA2006969A1 (en) 1990-07-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20101018