ES2104600T3 - Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido. - Google Patents

Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido.

Info

Publication number
ES2104600T3
ES2104600T3 ES90901711T ES90901711T ES2104600T3 ES 2104600 T3 ES2104600 T3 ES 2104600T3 ES 90901711 T ES90901711 T ES 90901711T ES 90901711 T ES90901711 T ES 90901711T ES 2104600 T3 ES2104600 T3 ES 2104600T3
Authority
ES
Spain
Prior art keywords
polypeptide
dna
activity
chemototic
codes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90901711T
Other languages
English (en)
Inventor
Yasuji Furutani
Toshikazu Fukui
Yamagishi Junichi
Yamada Masaaki
Kouji Matsushima
Joost Oppenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Commerce
Original Assignee
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2104600(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP64000065A external-priority patent/JP2893112B2/ja
Priority claimed from JP1026438A external-priority patent/JP2992640B2/ja
Application filed by US Department of Commerce filed Critical US Department of Commerce
Application granted granted Critical
Publication of ES2104600T3 publication Critical patent/ES2104600T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

UN PROCEDIMIENTO PARA LA PRODUCCION DE UN POLIPEPTIDO QUE TIENE ACTIVIDAD DE FACTOR QUEMOTACTICO DE MONOCITOS HUMANOS. COMPRENDE CULTIVAR UN HUESPED MICROBIANO TRANSFORMADO POR UN VECTOR DE EXPRESION QUE CONTIENE UNA SECUENCIA DE AMINO-ACIDOS REPRESENTADA POR LA SIGUIENTE FORMULA (I) O SU PORCION PRINCIPAL: GLN PRO ASP ALA ILE ASN ALA PRO VAL THR CYS CYS TYR ASN PHE THR ASN ARG LYS ILE SER VAL GLN ARG LEU ALA SER TYR ARG ARG ILE THR SER SER LYS CYS PRO LYS GLU ALA VAL ILE PHE LYS THR ILE VAL ALA LYS GLU ILE CYS X ASP PRO LYS GLN LYS TRP VAL GLN ASP SER MET ASP HIS LEU ASP LYS GLN THR GLN THR PRO LYS THR. EN DONDE X SIGNIFICA ALA O THR.
ES90901711T 1989-01-01 1990-01-02 Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido. Expired - Lifetime ES2104600T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP64000065A JP2893112B2 (ja) 1989-01-01 1989-01-01 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするｄｎａ
JP1026438A JP2992640B2 (ja) 1989-02-03 1989-02-03 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするｄｎａ並びにそれらの製法

Publications (1)

Publication Number Publication Date
ES2104600T3 true ES2104600T3 (es) 1997-10-16

Family

ID=26332976

Family Applications (2)

Application Number Title Priority Date Filing Date
ES09050005A Expired - Fee Related ES2056753A6 (es) 1989-01-01 1990-01-02 Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.
ES90901711T Expired - Lifetime ES2104600T3 (es) 1989-01-01 1990-01-02 Polipeptido que tiene actividad del factor quimiotactico de los monocitos humanos y adn que codifica dicho polipeptido.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES09050005A Expired - Fee Related ES2056753A6 (es) 1989-01-01 1990-01-02 Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.

Country Status (10)

Country Link
EP (1) EP0452391B1 (es)
JP (1) JPH04501961A (es)
AT (1) ATE155526T1 (es)
AU (1) AU642399B2 (es)
CA (1) CA2006969C (es)
DE (1) DE69031071T2 (es)
DK (1) DK0452391T3 (es)
ES (2) ES2056753A6 (es)
IL (1) IL92938A (es)
WO (1) WO1990007863A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92937A0 (en) 1989-01-31 1990-09-17 Us Health Human derived monocyte attracting protein,pharmaceutical compositions comprising it and dna encoding it
US6767535B1 (en) 1989-05-12 2004-07-27 Dana-Farber Cancer Institute, Inc. Suppressing tumor formation using cells expressing JE/monocyte chemoattractant protein-1
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
SG66214A1 (en) * 1990-09-05 1999-07-20 Heart Research Inst Ltd Novel chemotactic factor
FR2669930A1 (fr) * 1990-11-29 1992-06-05 Sanofi Sa Proteine presentant une activite de type cytokine, adn recombinant, vecteur d'expression et hotes permettant son obtention.
WO1992019737A1 (en) * 1991-05-09 1992-11-12 Dainippon Pharmaceutical Co., Ltd. Process for producing a monocyte chemotactic factor polypeptide and a strain for the production thereof
JPH0782169A (ja) * 1993-09-13 1995-03-28 Toray Ind Inc 創傷治療剤
US7265201B1 (en) 1995-06-23 2007-09-04 Millennium Pharmaceuticals, Inc. Human chemotactic cytokine
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
AU2006280004A1 (en) 2005-08-12 2007-02-22 Schering Corporation MCP1 fusions
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants

Also Published As

Publication number Publication date
ATE155526T1 (de) 1997-08-15
DE69031071T2 (de) 1998-02-05
DE69031071D1 (de) 1997-08-21
CA2006969A1 (en) 1990-07-01
ES2056753A6 (es) 1994-10-01
IL92938A0 (en) 1990-09-17
AU642399B2 (en) 1993-10-21
WO1990007863A1 (en) 1990-07-26
EP0452391B1 (en) 1997-07-16
DK0452391T3 (da) 1997-10-20
AU4845090A (en) 1990-08-13
JPH04501961A (ja) 1992-04-09
IL92938A (en) 1998-08-16
EP0452391A1 (en) 1991-10-23
CA2006969C (en) 2000-03-14
EP0452391A4 (en) 1992-06-03

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