ES2104596T3 - Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion. - Google Patents

Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.

Info

Publication number
ES2104596T3
ES2104596T3 ES90403232T ES90403232T ES2104596T3 ES 2104596 T3 ES2104596 T3 ES 2104596T3 ES 90403232 T ES90403232 T ES 90403232T ES 90403232 T ES90403232 T ES 90403232T ES 2104596 T3 ES2104596 T3 ES 2104596T3
Authority
ES
Spain
Prior art keywords
expression
preparation
allow
dna sequences
new polypeptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90403232T
Other languages
English (en)
Inventor
Dominique Petre
Edith Cerbelaud
Jean-Francois Mayaux
Patrice Yeh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of ES2104596T3 publication Critical patent/ES2104596T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A UNA SECUENCIA DE CODIFICACION DEL DNA PARA UN POLIPEPTIDO CON ACTIVIDAD AMIDASA ENANTIOSELECTIVA.
ES90403232T 1989-12-11 1990-11-15 Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion. Expired - Lifetime ES2104596T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8916332A FR2655660B1 (fr) 1989-12-11 1989-12-11 Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.

Publications (1)

Publication Number Publication Date
ES2104596T3 true ES2104596T3 (es) 1997-10-16

Family

ID=9388350

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90403232T Expired - Lifetime ES2104596T3 (es) 1989-12-11 1990-11-15 Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.

Country Status (20)

Country Link
US (2) US5260208A (es)
EP (1) EP0433117B1 (es)
JP (1) JP3150335B2 (es)
KR (1) KR0164850B1 (es)
CN (1) CN1052508A (es)
AT (1) ATE152481T1 (es)
AU (1) AU631696B2 (es)
CA (1) CA2030073C (es)
DE (1) DE69030615T2 (es)
DK (1) DK0433117T3 (es)
ES (1) ES2104596T3 (es)
FI (1) FI102971B (es)
FR (1) FR2655660B1 (es)
GR (1) GR3024316T3 (es)
HU (1) HUT56138A (es)
IE (1) IE904115A1 (es)
IL (1) IL96309A0 (es)
NZ (1) NZ236087A (es)
PT (1) PT95909B (es)
ZA (1) ZA909071B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2655660B1 (fr) * 1989-12-11 1992-03-20 Rhone Poulenc Sante Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.
EP0524604B1 (de) * 1991-07-26 1998-10-14 Lonza A.G. Gentechnologisches Verfahren zur Herstellung von S-(+)-2,2-Dimethylcyclopropancarboxamid mittels Mikroorganismen
US5258305A (en) * 1991-09-13 1993-11-02 Nitto Chemical Industry Co., Ltd. Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi
DE4226971C2 (de) * 1992-08-14 1997-01-16 Widmar Prof Dr Tanner Modifizierte Pilzzellen und Verfahren zur Herstellung rekombinanter Produkte
US6051431A (en) * 1994-07-22 2000-04-18 Dsm N.V. Selection marker gene free recombinant strains: a method for obtaining them and the use of these strains
AU7514896A (en) 1995-10-06 1997-04-28 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
PT954571E (pt) * 1996-04-25 2007-12-07 Novartis Ag Biocatalisadores com actividade de aminoacilase
CA2259954C (en) 1996-07-10 2012-03-06 Lonza Ag Process for the preparation of (s)- or (r)-3,3,3-trifluoro-2-hydroxy-2-methylpropionic acid
US6207647B1 (en) * 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
EP0905250A1 (en) * 1997-08-13 1999-03-31 Smithkline Beecham Corporation The Chlamydia trachomatis Glutamyl-tRNAGln amidotransferase subunit ratA
WO2000063354A1 (en) * 1999-04-16 2000-10-26 Mitsubishi Rayon Co., Ltd. Novel amidase gene
CN1311197A (zh) * 2000-03-02 2001-09-05 上海博德基因开发有限公司 一种新的多肽——酰胺酶家族蛋白13和编码这种多肽的多核苷酸
JPWO2002052027A1 (ja) * 2000-12-22 2004-04-30 日本曹達株式会社 微生物触媒を用いた物質生産方法
EP1428876B1 (en) * 2001-08-28 2008-05-21 Mitsubishi Rayon Co., Ltd. Novel amide hydrolase gene
TW201002823A (en) * 2008-05-20 2010-01-16 Dsm Ip Assets Bv Preparation of alpha-amino-epsilon-caprolactam via lysine cyclisation
EP2123767A1 (en) * 2008-05-20 2009-11-25 DSM IP Assets B.V. Preparation of epsilon-caprolactam via lysine cyclisation
CN111363736A (zh) * 2020-03-12 2020-07-03 东莞市东阳光生物合成药有限公司 制备右旋酮洛芬的方法
CN116334151A (zh) * 2023-03-24 2023-06-27 浙江九洲药业股份有限公司 一种合成右旋酮洛芬的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU74142A1 (es) * 1976-01-08 1977-07-22
JPS5713000A (en) * 1980-06-24 1982-01-22 Ube Ind Ltd Preparation of optical active tryptophane
US4366250A (en) * 1980-09-24 1982-12-28 Anvar Preparation process of optically active α-aminated acids by biological hydrolysis of nitriles
JPS57186495A (en) * 1981-05-14 1982-11-16 Ube Ind Ltd Preparation of l-alpha-methylphenylalanine
JPS58192900A (ja) * 1982-05-04 1983-11-10 Ajinomoto Co Inc 複合プラスミド
US4925799A (en) * 1983-01-12 1990-05-15 The United States Of America As Represented By The Department Of Health And Human Services Plasmid cloning vector pAS1
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4921699A (en) * 1983-06-01 1990-05-01 Hoffman-La Roche Inc. Polypeptides having interferon activity
US4861722A (en) * 1983-08-24 1989-08-29 Ajinomoto Company, Inc. Coryneform bacteria carrying recombinant plasmids and their use in the fermentative production of L-lysine
NL8400312A (nl) * 1984-02-02 1985-09-02 Stamicarbon Optisch aktief gesubstitueerd boterzuuramide alsmede werkwijze voor de optische scheiding van gesubstitueerd boterzuuramide.
DE3435156A1 (de) * 1984-09-25 1986-04-03 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung der stereoisomeren von 1-amino-alkylphosphonsaeuren oder 1-aminoalkylphosphinsaeuren
NL8501093A (nl) * 1985-04-12 1986-11-03 Stamicarbon Werkwijze voor het racemiseren van een optisch aktief n- benzylideenaminozuuramide.
US4920054A (en) * 1986-07-25 1990-04-24 Allelix, Inc. Shuttle vectors from rhodococcus equi
GB2195630B (en) * 1986-08-26 1990-07-18 Chuo Kaseihin Co Inc Method for producing carnitine, l-carnitineamide hydrolase and method for producing same
US4965197A (en) * 1987-06-12 1990-10-23 Massachusetts Institute Of Technology Coryneform expression and secretion system
EP0330695B1 (en) * 1987-08-17 1992-11-11 Novo Nordisk A/S Process for preparation of organic chemicals
FR2626288B1 (es) * 1988-01-27 1990-05-18 Rhone Poulenc Sante
FR2626289B1 (fr) * 1988-01-27 1990-06-08 Rhone Poulenc Sante Procede de preparation d'acides aryl-2 alkanoiques optiquement actifs
GB2218985A (en) * 1988-05-27 1989-11-29 Shell Int Research Producing optically active 2-aryloxypropionic acids
FR2655660B1 (fr) * 1989-12-11 1992-03-20 Rhone Poulenc Sante Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.

Also Published As

Publication number Publication date
IE904115A1 (en) 1991-06-19
US5260208A (en) 1993-11-09
PT95909A (pt) 1991-09-30
ZA909071B (en) 1991-09-25
US5766918A (en) 1998-06-16
CA2030073C (en) 2001-10-30
JP3150335B2 (ja) 2001-03-26
DE69030615T2 (de) 1997-11-06
CA2030073A1 (en) 1991-06-12
IL96309A0 (en) 1991-08-16
FI102971B1 (fi) 1999-03-31
NZ236087A (en) 1992-11-25
FI905660L (fi) 1991-06-12
AU6661490A (en) 1991-06-13
FI905660A0 (fi) 1990-11-15
FI102971B (fi) 1999-03-31
HUT56138A (en) 1991-07-29
AU631696B2 (en) 1992-12-03
KR0164850B1 (ko) 1999-01-15
PT95909B (pt) 1998-01-30
FR2655660A1 (fr) 1991-06-14
KR910012245A (ko) 1991-08-07
EP0433117B1 (en) 1997-05-02
JPH04218379A (ja) 1992-08-07
HU907151D0 (en) 1991-05-28
DE69030615D1 (de) 1997-06-05
EP0433117A1 (en) 1991-06-19
GR3024316T3 (en) 1997-10-31
FR2655660B1 (fr) 1992-03-20
CN1052508A (zh) 1991-06-26
ATE152481T1 (de) 1997-05-15
DK0433117T3 (da) 1997-11-03

Similar Documents

Publication Publication Date Title
ES2104596T3 (es) Nuevos polipeptidos, secuencias de adn que permiten su expresion, metodo de preparacion, y utilizacion.
ES8401133A1 (es) Metodo para preparar albumina de suero humano o una proteina de fusion de la misma.
ES2163864T3 (es) Secuencias de dna de 2-desoxiglucosa-6-fosfato (2-dog-6-p) como marcador de seleccion en plantas.
ES8602121A1 (es) Procedimiento para producir un vehiculo de expresion para la formacion de uroquinasa humana
ES2072900T3 (es) Expresion elevada de proteinas en levadura.
AR241314A1 (es) Aislado de adn, vector en base en dicho aislado cultivo de celulas tratadas con dicho vector y preparacion de factor viii humano funcional.
ZA91134B (en) New proteins produced by human lymphocytes,dna sequence encoding these proteins and their pharmaceutical and biological uses
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
ES8705521A1 (es) Un metodo de producir un polipetido similar a factor de necrosis de tumores (tnf) de mamiferos.
ES2009210A6 (es) Un procedimiento para la obtencion de nuevos polipeptidos que proporcionan anticuerpos frente a virus de sida, yno reaccionantes con anticuerpos sida.
ATE380875T1 (de) Chimäre proteine zur vermeidung der komplementaktivierung
ES8402351A1 (es) Procedimiento para producir interferon inmune humano.
ES2056817T3 (es) Transformacion de trichoderma.
FI101720B1 (fi) Synteettisen DNA:n konstruointi ja sen käyttö suurten polypeptidien synteesissä
ES2052580T3 (es) Nuevas formas de factor-1 estimulante de colonias.
ATE182901T1 (de) Für androgen-rezeptor-protein kodierende dna
GB9209993D0 (en) Vaccines
ES552431A0 (es) Procedimiento para preparar plasmidos de expresion prhw11 y prhw12
ES2064324T3 (es) Adn que codifica para un polipeptido con actividades anticoagulantes.
AR246310A1 (es) Procedimiento para la preparacion de la cadena alfa- del receptor de la interleucina 5 humana, o partes del mismo, secuencia del adn, vector y celula hospedante.
FI863626A7 (fi) DNA-sekvenssejä, yhdistelmä-DNA -molekyylejä ja menetelmiä ihmisen lip okortiinin kaltaisia polypeptidejä.
FI896261A7 (fi) Menetelmä proteiinin tai polypeptidin valmistamiseksi, polypeptidiä ko odaava DNA-sekvenssi, DNA-sekvenssin sisältämä mikro-organismi sekä po lypeptidi ja sen käyttö farmaseuttisena valmisteena
CO4480058A1 (es) Genes codificantes y procedimiento de expresion de una nueva enzima: ftalil amidasa
DK0774004T3 (da) DNA-sekvens, som koder for de humane proteiner Tx og Ty, der er beslægtede med Interleukin-1betakonverterende enzym
ES2121754T3 (es) Fragmento de adnc que codifica el gen del receptor del interferon alfa y procedimiento para la preparacion de una proteina correspondiente.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 433117

Country of ref document: ES