DE69031071D1 - Polypeptid mit einer aktivität des menschlichen monocyten chemotaktischen faktors und dna, kodierend für das polypeptid - Google Patents

Polypeptid mit einer aktivität des menschlichen monocyten chemotaktischen faktors und dna, kodierend für das polypeptid

Info

Publication number
DE69031071D1
DE69031071D1 DE69031071T DE69031071T DE69031071D1 DE 69031071 D1 DE69031071 D1 DE 69031071D1 DE 69031071 T DE69031071 T DE 69031071T DE 69031071 T DE69031071 T DE 69031071T DE 69031071 D1 DE69031071 D1 DE 69031071D1
Authority
DE
Germany
Prior art keywords
polypeptide
dna
activity
chemotactic factor
encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69031071T
Other languages
English (en)
Other versions
DE69031071T2 (de
Inventor
Yasuji Furutani
Toshikazu Fukui
Yamagishi Junichi
Yamada Masaaki
Kouji Matsushima
Joost Oppenheim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Commerce
Original Assignee
US Department of Commerce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26332976&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69031071(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from JP64000065A external-priority patent/JP2893112B2/ja
Priority claimed from JP1026438A external-priority patent/JP2992640B2/ja
Application filed by US Department of Commerce filed Critical US Department of Commerce
Application granted granted Critical
Publication of DE69031071D1 publication Critical patent/DE69031071D1/de
Publication of DE69031071T2 publication Critical patent/DE69031071T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/521Chemokines
    • C07K14/523Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69031071T 1989-01-01 1990-01-02 Polypeptid mit einer aktivität des menschlichen monocyten chemotaktischen faktors und dna, kodierend für das polypeptid Expired - Lifetime DE69031071T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP64000065A JP2893112B2 (ja) 1989-01-01 1989-01-01 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするdna
JP1026438A JP2992640B2 (ja) 1989-02-03 1989-02-03 ヒト単球走化性因子活性を有するポリペプチド及びそれをコードするdna並びにそれらの製法
PCT/US1990/000040 WO1990007863A1 (en) 1989-01-01 1990-01-02 A polypeptide having human monocyte chemotactic factor activity and a dna encoding said polypeptide

Publications (2)

Publication Number Publication Date
DE69031071D1 true DE69031071D1 (de) 1997-08-21
DE69031071T2 DE69031071T2 (de) 1998-02-05

Family

ID=26332976

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69031071T Expired - Lifetime DE69031071T2 (de) 1989-01-01 1990-01-02 Polypeptid mit einer aktivität des menschlichen monocyten chemotaktischen faktors und dna, kodierend für das polypeptid

Country Status (10)

Country Link
EP (1) EP0452391B1 (de)
JP (1) JPH04501961A (de)
AT (1) ATE155526T1 (de)
AU (1) AU642399B2 (de)
CA (1) CA2006969C (de)
DE (1) DE69031071T2 (de)
DK (1) DK0452391T3 (de)
ES (2) ES2056753A6 (de)
IL (1) IL92938A (de)
WO (1) WO1990007863A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92937A0 (en) 1989-01-31 1990-09-17 Us Health Human derived monocyte attracting protein,pharmaceutical compositions comprising it and dna encoding it
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
US6767535B1 (en) 1989-05-12 2004-07-27 Dana-Farber Cancer Institute, Inc. Suppressing tumor formation using cells expressing JE/monocyte chemoattractant protein-1
ATE228164T1 (de) * 1990-09-05 2002-12-15 Heart Res Inst Ltd Chemotaktische faktoren
US6001649A (en) * 1990-11-29 1999-12-14 Societe Anonyme: Elf Sanofi Chemokine NC28 (monocyte chemotactic protein-3, MCP-3) polypeptides and their recombinant production
WO1992019737A1 (en) * 1991-05-09 1992-11-12 Dainippon Pharmaceutical Co., Ltd. Process for producing a monocyte chemotactic factor polypeptide and a strain for the production thereof
JPH0782169A (ja) * 1993-09-13 1995-03-28 Toray Ind Inc 創傷治療剤
US7265201B1 (en) 1995-06-23 2007-09-04 Millennium Pharmaceuticals, Inc. Human chemotactic cytokine
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
AU2006280004A1 (en) 2005-08-12 2007-02-22 Schering Corporation MCP1 fusions
US8524217B2 (en) 2010-05-11 2013-09-03 Merck Sharp & Dohme Corp. MCP1-Ig fusion variants

Also Published As

Publication number Publication date
EP0452391B1 (de) 1997-07-16
AU4845090A (en) 1990-08-13
AU642399B2 (en) 1993-10-21
JPH04501961A (ja) 1992-04-09
CA2006969C (en) 2000-03-14
ATE155526T1 (de) 1997-08-15
CA2006969A1 (en) 1990-07-01
IL92938A0 (en) 1990-09-17
EP0452391A1 (de) 1991-10-23
DE69031071T2 (de) 1998-02-05
EP0452391A4 (en) 1992-06-03
ES2056753A6 (es) 1994-10-01
IL92938A (en) 1998-08-16
ES2104600T3 (es) 1997-10-16
DK0452391T3 (da) 1997-10-20
WO1990007863A1 (en) 1990-07-26

Similar Documents

Publication Publication Date Title
DE69031071D1 (de) Polypeptid mit einer aktivität des menschlichen monocyten chemotaktischen faktors und dna, kodierend für das polypeptid
DK135488D0 (da) Il-3-protein, isaer humant il-3, dets fremstilling og anvendelse i farmaceutica, vektor, som koder proteinet, samt celler transformeret med vektoren
PT83813B (pt) Processo para a preparacao de proteinas de fusao eucarioticas
ATE358176T1 (de) Menschliche dnase
DE69833667D1 (de) Polynukleotid kodierend für ein polypeptid mit heparanase-aktivität und dessen expression in transduzierten zellen
ES2010538A6 (es) Procedimiento para la preparacion de un gen sintetico.
DK268882A (da) Fremgangsmaade til fremstilling af et polypeptid, dna-sekvens, som koder for polypeptidet, replicerbart mikrobielt udtrykkelsesmedium, som i en transformant-mikroorganisme er i stand til at udtrykke polypeptidet og kultur af en mikroorganisme transformeret dermed
ES8506347A1 (es) Un metodo para producir un polipeptido de tipo il-2-".
DE69233463D1 (de) Expression und reinigung von kloniertem humanen alpha-fetoprotein
DE3482840D1 (de) Expressionsvektoren und deren verwendung zur herstellung eines proteins mit menschlicher alpha-antitrypsin-aktivitaet.
ATE132900T1 (de) Gene, die ein protein mit menschlicher macif- aktivität kodieren, expressionsvektoren mit diesen genen, transformantenzellen und proteine mit menschlicher macif-aktivität
DK38889A (da) Onkogen-indkodet polypeptid med vaekstfaktoraktivitet
DE68920321T2 (de) Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.
DE69329190D1 (de) Autotaxin : ein das selbständige zellbewegungsvermögen stimulierendes protein nützlich in der krebs-diagnostik und therapie
DE3886517T2 (de) Menschlicher Prourokinase ähnliches Polypeptid.
AR243237A1 (es) Un vector de expresion recombinante que contiene una secuencia de adn que codifica el factor neurotrofico ciliar humano,un microorganismo e.coli transformado,y linea celulares transformadas.
EP0315118A3 (de) Endothelin kodierendes DNA und dessen Verwendung
DE69116704D1 (de) Gen, das ein Polypeptid mit Nitrilhydratase-Aktivität codiert, eine dieses Gen enthaltende Transformante und Verfahren zur Herstellung von Amiden mit dieser Transformante.
ES8605296A1 (es) Procedimiento de producir factor viii-r humano
ES2111537T3 (es) Inhibidor de la ribonucleasa de placenta humana recombinante y metodo de produccion.
EP0281089A3 (en) Process for the preparation of factor viii:c deficient plasma, and deficient plasma obtained therwith
DE3853590D1 (de) Rinder granulocyt-makrophagenkolonie stimulierender faktor.
ATE55150T1 (de) Expressionsvektoren und deren verwendung zur herstellung eines proteins mit menschlicher alpha-antitrypsin-aktivitaet.
ATE98990T1 (de) Menschlicher prourokinase aehnliches polypeptid.
DE68919619D1 (de) DNA-Sequenz, beteiligt an der Regulation der Expression einer DNA-Sequenz, die einen Polypeptid-Precursor kodiert, Expressionsvektoren und Methode der periplasmatischen Herstellung des Polypeptides.

Legal Events

Date Code Title Description
8363 Opposition against the patent