DE68920321T2 - Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids. - Google Patents

Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.

Info

Publication number
DE68920321T2
DE68920321T2 DE68920321T DE68920321T DE68920321T2 DE 68920321 T2 DE68920321 T2 DE 68920321T2 DE 68920321 T DE68920321 T DE 68920321T DE 68920321 T DE68920321 T DE 68920321T DE 68920321 T2 DE68920321 T2 DE 68920321T2
Authority
DE
Germany
Prior art keywords
human
chemotactic factor
polypeptid
producing
neutrophil chemotactic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68920321T
Other languages
English (en)
Other versions
DE68920321D1 (de
Inventor
Kouji Matsushima
Teizo Yoshimura
Masaaki Yamada
Ryuji Furuta
Junichi Yamagishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
US Department of Health and Human Services
Original Assignee
US Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by US Department of Health and Human Services filed Critical US Department of Health and Human Services
Application granted granted Critical
Publication of DE68920321D1 publication Critical patent/DE68920321D1/de
Publication of DE68920321T2 publication Critical patent/DE68920321T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5421IL-8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE68920321T 1988-05-02 1989-04-26 Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids. Expired - Lifetime DE68920321T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18916488A 1988-05-02 1988-05-02
PCT/JP1989/000437 WO1989010962A1 (en) 1988-05-02 1989-04-26 Process for producing a human neutrophil chemotactic factor polypeptide

Publications (2)

Publication Number Publication Date
DE68920321D1 DE68920321D1 (de) 1995-02-09
DE68920321T2 true DE68920321T2 (de) 1995-05-24

Family

ID=22696203

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68920321T Expired - Lifetime DE68920321T2 (de) 1988-05-02 1989-04-26 Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.

Country Status (7)

Country Link
US (1) US5306627A (de)
EP (1) EP0413818B1 (de)
JP (1) JPH03505037A (de)
KR (1) KR900700615A (de)
AT (1) ATE116366T1 (de)
DE (1) DE68920321T2 (de)
WO (1) WO1989010962A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2223225B (en) 1987-11-19 1992-07-08 Sandoz Ltd Neutrophil-activating factor: its production and use in treatment
US5652338A (en) * 1988-03-16 1997-07-29 The United States Of America As Represented By The Department Of Health And Human Services Neutrophil chemotactic factor
WO1991008231A1 (en) * 1989-11-29 1991-06-13 Brigham And Women's Hospital [Ala IL-8]77 AS A LEUKOCYTE ADHESION INHIBITOR
US5241049A (en) * 1989-12-22 1993-08-31 Zymogenetics, Inc. Neutrophil chemoattractants
US7282568B2 (en) 2002-12-16 2007-10-16 Medarex, Inc. Human monoclonal antibodies against interleukin 8 (IL-8)
JP2007006419A (ja) * 2005-06-27 2007-01-11 Pioneer Electronic Corp スピーカ用ダンパ、スピーカおよびスピーカの組立方法
CA3084370A1 (en) 2018-01-12 2019-07-18 Bristol-Myers Squibb Company Combination therapy with anti-il-8 antibodies and anti-pd-1 antibodies for treating cancer

Also Published As

Publication number Publication date
KR900700615A (ko) 1990-08-16
EP0413818A1 (de) 1991-02-27
EP0413818B1 (de) 1994-12-28
WO1989010962A1 (en) 1989-11-16
JPH03505037A (ja) 1991-11-07
ATE116366T1 (de) 1995-01-15
DE68920321D1 (de) 1995-02-09
US5306627A (en) 1994-04-26

Similar Documents

Publication Publication Date Title
DE68916537T3 (de) Herstellung eines insulinähnlichen, wachstümsfaktor bindenden proteins.
DE3781765T2 (de) Verfahren zur herstellung eines polypeptides.
FI20090384A (fi) Menetelmä modifioidun G-CSF-polypeptidin valmistamiseksi
IE811463L (en) Interferons
ATE121781T1 (de) Verwendung von dns-fragmenten, die ein signalpeptid kodieren zur sekretion von reifen proteinen in rekombinanten hefen, expressions- kassetten, transformierte hefen und verfahren zur herstellung dieser proteine.
ATE217887T1 (de) Verfahren zur herstellung von wasserlöslichen polypeptiden
ES8306324A1 (es) "proceso para la produccion microbiana de interferon fibroblasto humano".
DE68928892T2 (de) Rekombinante DNA, transformierte Mikroorganismen, Pflanzenzellen und Pflanzen, Verfahren zur Einführung einer induzierbaren Eigenschaft in Pflanzen und Verfahren zur Herstellung eines Polypeptids oder Proteins mit Hilfe von Pflanzen oder Pflanzenzellen
DE3587422D1 (de) Fuer ein hirudinaehnliches protein kodierende dns-sequenz und verfahren zur herstellung eines solchen proteins.
HUT46065A (en) Process for producing new human tnf polypeptide mutants and dna encoding them
DK164940C (da) Polypeptid med human-gamma-interferonaktivitet, genteknologisk fremgangsmaade til fremstilling deraf, hybrid-plasmider indeholdende en dna-sekvens, der koder for peptidet, vaertsorganismer indeholdende hybridplasmiderne, samt laegemidler, som indeholder polypeptidet
KR910004803A (ko) 간의 실질 세포 성장 인자, 이를 코딩하는 유전자, 이 인자를 생산하는 방법, 및 이 인자를 생산하는 형질전환체
PT666914E (pt) Nova proteina ligando da selectina p
ES2056753A6 (es) Un procedimiento para la produccion de un polipeptido que tiene actividad de factor quemotactico de monocitos humanos.
DE68920321D1 (de) Verfahren zur herstellung eines menschlichen "neutrophil chemotactic factor"-polypeptids.
ATE194624T1 (de) Mutanten von menschlichem antithrombin iii
EP0315118A3 (de) Endothelin kodierendes DNA und dessen Verwendung
ATE109827T1 (de) Verfahren zur herstellung von peptiden, dazu zu verwendendes rekombinantes plasmid und mit diesem plasmid transformierte myelomzellen.
NO890174L (no) Rekombinante interleukin-1alfa-polypeptider.
ATE162853T1 (de) Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition