DK1719775T3 - Camptotheciner med en modificeret lactonring - Google Patents

Camptotheciner med en modificeret lactonring

Info

Publication number
DK1719775T3
DK1719775T3 DK06116366T DK06116366T DK1719775T3 DK 1719775 T3 DK1719775 T3 DK 1719775T3 DK 06116366 T DK06116366 T DK 06116366T DK 06116366 T DK06116366 T DK 06116366T DK 1719775 T3 DK1719775 T3 DK 1719775T3
Authority
DK
Denmark
Prior art keywords
camptothecins
lactone ring
modified lactone
modified
ring
Prior art date
Application number
DK06116366T
Other languages
Danish (da)
English (en)
Inventor
Mauro Marzi
Elena Marastoni
Sergio Penco
Claudio Pisano
Maria Ornella Tinti
Loredana Vesci
Franco Zunino
Domenico Vergani
Walter Cabri
Marco Alpegiani
Martin Patricio
Tamara Danelli
Original Assignee
Sigma Tau Ind Farmaceuti
Ist Naz Stud Cura Dei Tumori
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti, Ist Naz Stud Cura Dei Tumori filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1719775T3 publication Critical patent/DK1719775T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
DK06116366T 2002-05-31 2003-05-28 Camptotheciner med en modificeret lactonring DK1719775T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002RM000305A ITRM20020305A1 (it) 2002-05-31 2002-05-31 Camptotecine con anello lattonico modificato.
PCT/IT2003/000328 WO2003101995A2 (en) 2002-05-31 2003-05-28 Camptothecins with a modified lactone ring

Publications (1)

Publication Number Publication Date
DK1719775T3 true DK1719775T3 (da) 2008-11-17

Family

ID=11456338

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06116366T DK1719775T3 (da) 2002-05-31 2003-05-28 Camptotheciner med en modificeret lactonring
DK03730480.5T DK1511752T5 (da) 2002-05-31 2003-05-28 Camptotheciner med modificeret lactonring

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK03730480.5T DK1511752T5 (da) 2002-05-31 2003-05-28 Camptotheciner med modificeret lactonring

Country Status (22)

Country Link
US (1) US7273873B2 (enExample)
EP (2) EP1511752B3 (enExample)
JP (1) JP4693410B2 (enExample)
KR (1) KR101042042B1 (enExample)
CN (1) CN1656100A (enExample)
AR (1) AR040139A1 (enExample)
AT (2) ATE403659T1 (enExample)
AU (2) AU2003241160B2 (enExample)
BR (2) BR0311333A (enExample)
CA (2) CA2485201C (enExample)
CY (2) CY1107311T1 (enExample)
DE (2) DE60322754D1 (enExample)
DK (2) DK1719775T3 (enExample)
ES (2) ES2312090T3 (enExample)
IT (1) ITRM20020305A1 (enExample)
MX (1) MXPA04011682A (enExample)
PE (1) PE20050120A1 (enExample)
PL (1) PL374346A1 (enExample)
PT (2) PT1719775E (enExample)
SI (2) SI1719775T1 (enExample)
TW (1) TWI325866B (enExample)
WO (1) WO2003101995A2 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2852606A1 (fr) * 2003-03-18 2004-09-24 Inst Nat Sante Rech Med Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie
ITRM20030344A1 (it) 2003-07-14 2005-01-15 Ist Naz Stud Cura Dei Tumori 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi.
ES2400607T3 (es) * 2007-08-01 2013-04-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Forma cristalina ll de 7-(dimetoxi-metil)camptotecina, su uso como compuesto intermedio y productos obtenidos a partir de la misma
CN102746314B (zh) * 2011-04-18 2016-07-06 华东师范大学 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途
CN104530066A (zh) * 2015-01-06 2015-04-22 华东师范大学 一类新型高喜树碱衍生物、制备方法和用途
WO2019222272A1 (en) 2018-05-14 2019-11-21 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
BR112021022008A2 (pt) 2019-05-14 2022-05-17 Nuvation Bio Inc Compostos de direcionamento a receptor de hormônio nuclear anticâncer
TW202131930A (zh) 2019-11-13 2021-09-01 美商諾維雪碧歐公司 抗癌核荷爾蒙受體標靶化合物
WO2022204184A1 (en) 2021-03-23 2022-09-29 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
AU2022269568A1 (en) 2021-05-03 2023-11-16 Nuvation Bio Inc. Anti-cancer nuclear hormone receptor-targeting compounds
JP2025532843A (ja) * 2022-09-28 2025-10-03 ニューベイション・バイオ・インコーポレイテッド 抗がん核内ホルモン受容体標的化化合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57116076A (en) * 1981-01-09 1982-07-19 Yakult Honsha Co Ltd Novel camptothecin derivative and its preparation
US4399276A (en) * 1981-01-09 1983-08-16 Kabushiki Kaisha Yakult Honsha 7-Substituted camptothecin derivatives
FR2532591A1 (fr) 1982-09-02 1984-03-09 Hutchinson Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins
CN1114608C (zh) * 1995-06-21 2003-07-16 科学研究与运用咨询公司 喜树碱类似物、其制备方法和药物应用及其药物组合物
ES2175919T3 (es) * 1999-03-09 2002-11-16 Sigma Tau Ind Farmaceuti Derivados del camptothecin con actividad antitumoral.

Also Published As

Publication number Publication date
ITRM20020305A0 (it) 2002-05-31
JP2005531602A (ja) 2005-10-20
EP1511752B1 (en) 2006-09-13
EP1511752B3 (en) 2010-03-10
WO2003101995A2 (en) 2003-12-11
DK1511752T5 (da) 2010-06-14
EP1511752B8 (en) 2007-04-18
DE60308368D1 (de) 2006-10-26
CY1107311T1 (el) 2012-11-21
ES2273002T7 (es) 2011-08-01
US20050154003A1 (en) 2005-07-14
TW200404806A (en) 2004-04-01
DE60308368T3 (de) 2010-09-16
ITRM20020305A1 (it) 2003-12-01
WO2003101995A3 (en) 2004-02-19
SI1719775T1 (sl) 2009-04-30
ATE339422T1 (de) 2006-10-15
AU2009236044B2 (en) 2011-03-24
PL374346A1 (en) 2005-10-17
WO2003101995A8 (en) 2004-12-23
PT1511752E (pt) 2007-01-31
BR0311333A (pt) 2005-03-15
BR0311329A (pt) 2005-02-22
TWI325866B (en) 2010-06-11
AU2003241160B2 (en) 2009-08-20
AR040139A1 (es) 2005-03-16
DE60322754D1 (de) 2008-09-18
CA2706635A1 (en) 2003-12-11
JP4693410B2 (ja) 2011-06-01
MXPA04011682A (es) 2005-03-31
CA2485201A1 (en) 2003-12-11
CN1656100A (zh) 2005-08-17
EP1719775A1 (en) 2006-11-08
CA2485201C (en) 2010-11-02
EP1719775B1 (en) 2008-08-06
ES2312090T3 (es) 2009-02-16
KR101042042B1 (ko) 2011-06-16
AU2009236044B8 (en) 2011-07-21
PE20050120A1 (es) 2005-03-04
US7273873B2 (en) 2007-09-25
ES2273002T3 (es) 2007-05-01
SI1511752T1 (sl) 2007-02-28
ATE403659T1 (de) 2008-08-15
DE60308368T2 (de) 2007-09-06
AU2003241160A1 (en) 2003-12-19
AU2009236044A8 (en) 2011-07-21
AU2009236044A1 (en) 2009-12-03
EP1511752A2 (en) 2005-03-09
PT1719775E (pt) 2008-09-30
DK1511752T3 (da) 2007-01-29
KR20050036909A (ko) 2005-04-20
CY1108793T1 (el) 2014-04-09

Similar Documents

Publication Publication Date Title
DE60330079D1 (de) Ölring
DE03726967T1 (de) Wirbelringerzeuger
NO20054339D0 (no) Forede bronnboringer med maksimal diameter
DK1490133T3 (da) Infusionsanordning med lavprofildrejeforbindelse
DK1467789T3 (da) Lægemiddeldispenser
DK1583763T3 (da) Benzoazolylpiperazinderivater med VR1-antagonistaktivitet
DK1560835T3 (da) Spirocykliske cyclohexan-derivater
FR2837895B1 (fr) Segment de piston
DE60332581D1 (de) Induktiver Stellungsgeber
ATE453811T1 (de) Synchronring
DE60332694D1 (de) Näherungssensor
DK1719775T3 (da) Camptotheciner med en modificeret lactonring
DE60239391D1 (de) rgungsringes mit großem parasitärem Widerstand
DE112005001543T5 (de) Entlüfteter Einspritzventil-Aussenring
DE50307081D1 (de) Gabelbrücke
FI20030333A7 (fi) MSM-anturi
FR2847399B1 (fr) Recepteur a configuration double
FR2838029B1 (fr) Bague
DE60200407D1 (de) Methylendioxy- Derivate
DE10393274D2 (de) Palettiergerät
DE20318238U1 (de) Beissring
FI20020799A0 (fi) Voimalaite
FR2848277B1 (fr) Segment de piston
ATA16062002A (de) Schlüsselanhänger
ES1052520Y (es) Dispositivo anillo abre-botellas