ATE339422T1 - Camptothecine mit modifiziertem lactonring - Google Patents
Camptothecine mit modifiziertem lactonringInfo
- Publication number
- ATE339422T1 ATE339422T1 AT03730480T AT03730480T ATE339422T1 AT E339422 T1 ATE339422 T1 AT E339422T1 AT 03730480 T AT03730480 T AT 03730480T AT 03730480 T AT03730480 T AT 03730480T AT E339422 T1 ATE339422 T1 AT E339422T1
- Authority
- AT
- Austria
- Prior art keywords
- camptothecine
- lactone ring
- modified lactone
- modified
- ring
- Prior art date
Links
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical compound C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 150000002596 lactones Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Epoxy Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002RM000305A ITRM20020305A1 (it) | 2002-05-31 | 2002-05-31 | Camptotecine con anello lattonico modificato. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE339422T1 true ATE339422T1 (de) | 2006-10-15 |
Family
ID=11456338
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03730480T ATE339422T1 (de) | 2002-05-31 | 2003-05-28 | Camptothecine mit modifiziertem lactonring |
| AT06116366T ATE403659T1 (de) | 2002-05-31 | 2003-05-28 | Camptothecine mit modifiziertem lactonring |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06116366T ATE403659T1 (de) | 2002-05-31 | 2003-05-28 | Camptothecine mit modifiziertem lactonring |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7273873B2 (enExample) |
| EP (2) | EP1511752B3 (enExample) |
| JP (1) | JP4693410B2 (enExample) |
| KR (1) | KR101042042B1 (enExample) |
| CN (1) | CN1656100A (enExample) |
| AR (1) | AR040139A1 (enExample) |
| AT (2) | ATE339422T1 (enExample) |
| AU (2) | AU2003241160B2 (enExample) |
| BR (2) | BR0311329A (enExample) |
| CA (2) | CA2706635A1 (enExample) |
| CY (2) | CY1107311T1 (enExample) |
| DE (2) | DE60308368T3 (enExample) |
| DK (2) | DK1719775T3 (enExample) |
| ES (2) | ES2312090T3 (enExample) |
| IT (1) | ITRM20020305A1 (enExample) |
| MX (1) | MXPA04011682A (enExample) |
| PE (1) | PE20050120A1 (enExample) |
| PL (1) | PL374346A1 (enExample) |
| PT (2) | PT1719775E (enExample) |
| SI (2) | SI1719775T1 (enExample) |
| TW (1) | TWI325866B (enExample) |
| WO (1) | WO2003101995A2 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2852606A1 (fr) * | 2003-03-18 | 2004-09-24 | Inst Nat Sante Rech Med | Moyens pour inhiber simultanement l'expression de plusieurs genes impliques dans une pathologie |
| ITRM20030344A1 (it) | 2003-07-14 | 2005-01-15 | Ist Naz Stud Cura Dei Tumori | 7-n-poliamminoalchil(ossi)imminometilcamptotecine recanti gruppi protettivi. |
| HRP20121053T1 (hr) | 2007-08-01 | 2013-01-31 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Kristalni oblik ii 7-(dimetoksimetil)kamptotecina, njegova upotreba kao međuprodukta, te upotreba produkata dobivenih iz istog |
| CN102746314B (zh) * | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
| CN104530066A (zh) * | 2015-01-06 | 2015-04-22 | 华东师范大学 | 一类新型高喜树碱衍生物、制备方法和用途 |
| EA202092436A1 (ru) | 2018-05-14 | 2021-05-04 | Нувейшн Био Инк. | Противораковые соединения, нацеливающие на ядерные гормональные рецепторы |
| CA3138197A1 (en) | 2019-05-14 | 2020-11-19 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| US11952349B2 (en) | 2019-11-13 | 2024-04-09 | Nuvation Bio Inc. | Anti-cancer nuclear hormone receptor-targeting compounds |
| IL306010A (en) * | 2021-03-23 | 2023-11-01 | Nuvation Bio Inc | Anticancer compounds against the nuclear hormone receptor |
| JP2024516024A (ja) | 2021-05-03 | 2024-04-11 | ニューベイション・バイオ・インコーポレイテッド | 抗がん核内ホルモン受容体標的化化合物 |
| CA3267963A1 (en) * | 2022-09-28 | 2024-04-04 | Nuvation Bio Inc. | ANTICANCER COMPOUNDS TARGETING A NUCLEAR HORMONE RECEPTOR |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS57116076A (en) * | 1981-01-09 | 1982-07-19 | Yakult Honsha Co Ltd | Novel camptothecin derivative and its preparation |
| US4399276A (en) * | 1981-01-09 | 1983-08-16 | Kabushiki Kaisha Yakult Honsha | 7-Substituted camptothecin derivatives |
| FR2532591A1 (fr) | 1982-09-02 | 1984-03-09 | Hutchinson | Nouveau dispositif de securite pour pneumatiques de vehicules ou autres engins |
| JP3576171B2 (ja) | 1995-06-21 | 2004-10-13 | ソシエテ・ド・コンセイユ・ド・ルシエルシエ・エ・ダアツプリカーション・シヤンテイフイツク・（エス．セー．エール．アー．エス） | カンプトテシンの新規な同族体、その製造方法、その医薬としての用途及びこれを含有する医薬組成物 |
| PT1044977E (pt) * | 1999-03-09 | 2002-09-30 | Sigma Tau Ind Farmaceuti | Derivados de camptotecina com actividade antitumoral |
-
2002
- 2002-05-31 IT IT2002RM000305A patent/ITRM20020305A1/it unknown
-
2003
- 2003-05-26 TW TW092114164A patent/TWI325866B/zh not_active IP Right Cessation
- 2003-05-28 KR KR1020047016880A patent/KR101042042B1/ko not_active Expired - Fee Related
- 2003-05-28 US US10/511,724 patent/US7273873B2/en not_active Expired - Fee Related
- 2003-05-28 PT PT06116366T patent/PT1719775E/pt unknown
- 2003-05-28 ES ES06116366T patent/ES2312090T3/es not_active Expired - Lifetime
- 2003-05-28 DE DE60308368T patent/DE60308368T3/de not_active Expired - Lifetime
- 2003-05-28 AU AU2003241160A patent/AU2003241160B2/en not_active Ceased
- 2003-05-28 MX MXPA04011682A patent/MXPA04011682A/es active IP Right Grant
- 2003-05-28 SI SI200331380T patent/SI1719775T1/sl unknown
- 2003-05-28 CN CNA038125439A patent/CN1656100A/zh active Pending
- 2003-05-28 AT AT03730480T patent/ATE339422T1/de active
- 2003-05-28 ES ES03730480T patent/ES2273002T7/es active Active
- 2003-05-28 BR BR0311329-9A patent/BR0311329A/pt not_active IP Right Cessation
- 2003-05-28 EP EP03730480A patent/EP1511752B3/en not_active Expired - Lifetime
- 2003-05-28 PL PL03374346A patent/PL374346A1/xx unknown
- 2003-05-28 DK DK06116366T patent/DK1719775T3/da active
- 2003-05-28 JP JP2004509686A patent/JP4693410B2/ja not_active Expired - Fee Related
- 2003-05-28 SI SI200330509T patent/SI1511752T1/sl unknown
- 2003-05-28 CA CA2706635A patent/CA2706635A1/en not_active Abandoned
- 2003-05-28 CA CA2485201A patent/CA2485201C/en not_active Expired - Fee Related
- 2003-05-28 EP EP06116366A patent/EP1719775B1/en not_active Expired - Lifetime
- 2003-05-28 PT PT03730480T patent/PT1511752E/pt unknown
- 2003-05-28 DE DE60322754T patent/DE60322754D1/de not_active Expired - Lifetime
- 2003-05-28 AT AT06116366T patent/ATE403659T1/de active
- 2003-05-28 WO PCT/IT2003/000328 patent/WO2003101995A2/en not_active Ceased
- 2003-05-28 DK DK03730480.5T patent/DK1511752T5/da active
- 2003-05-28 BR BR0311333-7A patent/BR0311333A/pt not_active IP Right Cessation
- 2003-05-30 PE PE2003000529A patent/PE20050120A1/es not_active Application Discontinuation
- 2003-05-30 AR ARP030101915A patent/AR040139A1/es unknown
-
2006
- 2006-11-14 CY CY20061101648T patent/CY1107311T1/el unknown
-
2008
- 2008-10-31 CY CY20081101240T patent/CY1108793T1/el unknown
-
2009
- 2009-11-12 AU AU2009236044A patent/AU2009236044B8/en not_active Ceased
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