DK171236B1 - 2'-Desoxy-5-fluoruridinderivater, fremgangsmåder til fremstilling deraf samt farmaceutiske præparat omfattende en sådan forbindelse - Google Patents

2'-Desoxy-5-fluoruridinderivater, fremgangsmåder til fremstilling deraf samt farmaceutiske præparat omfattende en sådan forbindelse Download PDF

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Publication number
DK171236B1
DK171236B1 DK423988A DK423988A DK171236B1 DK 171236 B1 DK171236 B1 DK 171236B1 DK 423988 A DK423988 A DK 423988A DK 423988 A DK423988 A DK 423988A DK 171236 B1 DK171236 B1 DK 171236B1
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DK
Denmark
Prior art keywords
group
compound
deoxy
amino acid
compound according
Prior art date
Application number
DK423988A
Other languages
Danish (da)
English (en)
Other versions
DK423988D0 (da
DK423988A (da
Inventor
Yukio Tada
Atsuhiko Uemura
Mitsugi Yasumoto
Setsuo Takeda
Hitoshi Saito
Norio Unemi
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of DK423988D0 publication Critical patent/DK423988D0/da
Publication of DK423988A publication Critical patent/DK423988A/da
Application granted granted Critical
Publication of DK171236B1 publication Critical patent/DK171236B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DK423988A 1987-07-31 1988-07-29 2'-Desoxy-5-fluoruridinderivater, fremgangsmåder til fremstilling deraf samt farmaceutiske præparat omfattende en sådan forbindelse DK171236B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19319287 1987-07-31
JP19319287 1987-07-31

Publications (3)

Publication Number Publication Date
DK423988D0 DK423988D0 (da) 1988-07-29
DK423988A DK423988A (da) 1989-02-01
DK171236B1 true DK171236B1 (da) 1996-08-05

Family

ID=16303837

Family Applications (1)

Application Number Title Priority Date Filing Date
DK423988A DK171236B1 (da) 1987-07-31 1988-07-29 2'-Desoxy-5-fluoruridinderivater, fremgangsmåder til fremstilling deraf samt farmaceutiske præparat omfattende en sådan forbindelse

Country Status (12)

Country Link
US (1) US4946951A (zh)
EP (1) EP0301873B1 (zh)
KR (1) KR890002223A (zh)
CN (1) CN1022249C (zh)
AT (1) ATE106891T1 (zh)
AU (1) AU610913B2 (zh)
CA (1) CA1313866C (zh)
DE (1) DE3889993T2 (zh)
DK (1) DK171236B1 (zh)
ES (1) ES2053742T3 (zh)
FI (1) FI89497C (zh)
NO (1) NO883387L (zh)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0247381B1 (en) * 1986-04-30 1993-08-04 Otsuka Pharmaceutical Co., Ltd. 5-flurorouracil derivatives
EP0346108A3 (en) * 1988-06-09 1991-04-24 The Wellcome Foundation Limited Anti-infective nucleosides
JP3074341B2 (ja) * 1993-12-24 2000-08-07 大鵬薬品工業株式会社 ２’−デオキシ−５−フルオロウリジン誘導体
KR100394429B1 (ko) * 2000-03-15 2003-08-09 영진화학공업 주식회사 알릴아민계 항균첨가제 및 직물항균가공제와 그 제조방법및 직물항균가공방법
CN1315863C (zh) * 2003-12-12 2007-05-16 河南省科学院质量检验与分析测试研究中心 β－L－2'－脱氧－核苷衍生物、其合成方法及其药物用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658672A1 (de) * 1976-12-23 1978-06-29 Robugen Gmbh Neue nucleosid-verbindungen und verfahren zu ihrer herstellung
JPS5535057A (en) * 1978-09-05 1980-03-11 Funai Corp 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it
US4340728A (en) * 1979-11-28 1982-07-20 Fuji Kagaku Kogyo Kabushiki Kaisha Nucleoside derivatives and process for preparing same
DE3002197A1 (de) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel
JPS5791994A (en) * 1980-11-26 1982-06-08 Fuji Kagaku Kogyo Kk 5'-o-(n-alkylcarbamoylalanyl)-5-fluorouridine and its preparation
DE3263939D1 (en) * 1981-12-09 1985-07-04 Teijin Ltd 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
JPS5929699A (ja) * 1982-08-11 1984-02-16 Funai Corp ２′−デオキシ−５−フルオロウリジンのエ−テル誘導体およびその製造方法並びにこれを含有する抗腫瘍剤
DE3469533D1 (en) * 1983-05-23 1988-04-07 Taiho Pharmaceutical Co Ltd Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
DE3481191D1 (de) * 1983-07-20 1990-03-08 Teijin Ltd Antineoplastisches mittel.
DK174238B1 (da) * 1984-10-30 2002-10-07 Otsuka Pharma Co Ltd 5-Fluoruracilderivater, deres fremstilling og lægemidler indeholdende sådanne forbindelser
JPS61189292A (ja) * 1985-02-15 1986-08-22 Funai Corp ５−フルオロデオキシウリジン誘導体の新規な固溶体及びこれを活性成分として含有する制癌剤
JPS62187484A (ja) * 1986-02-12 1987-08-15 Taiho Yakuhin Kogyo Kk ３′−０−ベンジル−２′−デオキシ−β−ウリジン類の製造方法
EP0247381B1 (en) * 1986-04-30 1993-08-04 Otsuka Pharmaceutical Co., Ltd. 5-flurorouracil derivatives

Also Published As

Publication number Publication date
DK423988D0 (da) 1988-07-29
ES2053742T3 (es) 1994-08-01
NO883387L (no) 1989-02-01
NO883387D0 (no) 1988-07-29
EP0301873A3 (en) 1990-11-28
FI89497C (fi) 1993-10-11
US4946951A (en) 1990-08-07
CN1022249C (zh) 1993-09-29
DK423988A (da) 1989-02-01
DE3889993T2 (de) 1994-09-22
ATE106891T1 (de) 1994-06-15
CN1032169A (zh) 1989-04-05
AU610913B2 (en) 1991-05-30
KR890002223A (ko) 1989-04-10
DE3889993D1 (de) 1994-07-14
CA1313866C (en) 1993-02-23
AU2002288A (en) 1989-02-02
FI883584A0 (fi) 1988-07-29
FI883584A (fi) 1989-02-01
EP0301873A2 (en) 1989-02-01
EP0301873B1 (en) 1994-06-08
FI89497B (fi) 1993-06-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed