FI883584A - Foerfarande foer framstaellning av 2'-deoxi-5-fluorouridins derivat. - Google Patents

Foerfarande foer framstaellning av 2'-deoxi-5-fluorouridins derivat. Download PDF

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Publication number
FI883584A
FI883584A FI883584A FI883584A FI883584A FI 883584 A FI883584 A FI 883584A FI 883584 A FI883584 A FI 883584A FI 883584 A FI883584 A FI 883584A FI 883584 A FI883584 A FI 883584A
Authority
FI
Finland
Prior art keywords
group
deoxy
fluorouridins
derivat
framstaellning
Prior art date
Application number
FI883584A
Other languages
English (en)
Other versions
FI89497C (fi
FI89497B (fi
FI883584A0 (fi
Inventor
Yukio Tada
Atsuhiko Uemura
Mitsugi Yasumoto
Setsuo Takeda
Hitoshi Saito
Norio Unemi
Original Assignee
Taiho Pharmaceutical Co Ltd
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, Otsuka Pharma Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Publication of FI883584A0 publication Critical patent/FI883584A0/fi
Publication of FI883584A publication Critical patent/FI883584A/fi
Application granted granted Critical
Publication of FI89497B publication Critical patent/FI89497B/fi
Publication of FI89497C publication Critical patent/FI89497C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI883584A 1987-07-31 1988-07-29 Foerfarande foer framstaellning av 2'-deoxi-5-fluoruridins derivat FI89497C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19319287 1987-07-31
JP19319287 1987-07-31

Publications (4)

Publication Number Publication Date
FI883584A0 FI883584A0 (fi) 1988-07-29
FI883584A true FI883584A (fi) 1989-02-01
FI89497B FI89497B (fi) 1993-06-30
FI89497C FI89497C (fi) 1993-10-11

Family

ID=16303837

Family Applications (1)

Application Number Title Priority Date Filing Date
FI883584A FI89497C (fi) 1987-07-31 1988-07-29 Foerfarande foer framstaellning av 2'-deoxi-5-fluoruridins derivat

Country Status (12)

Country Link
US (1) US4946951A (fi)
EP (1) EP0301873B1 (fi)
KR (1) KR890002223A (fi)
CN (1) CN1022249C (fi)
AT (1) ATE106891T1 (fi)
AU (1) AU610913B2 (fi)
CA (1) CA1313866C (fi)
DE (1) DE3889993T2 (fi)
DK (1) DK171236B1 (fi)
ES (1) ES2053742T3 (fi)
FI (1) FI89497C (fi)
NO (1) NO883387L (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2058073T3 (es) * 1986-04-30 1994-11-01 Otsuka Pharma Co Ltd Derivados de 5-fluorouracilo.
EP0346108A3 (en) * 1988-06-09 1991-04-24 The Wellcome Foundation Limited Anti-infective nucleosides
JP3074341B2 (ja) * 1993-12-24 2000-08-07 大鵬薬品工業株式会社 ２’−デオキシ−５−フルオロウリジン誘導体
KR100394429B1 (ko) * 2000-03-15 2003-08-09 영진화학공업 주식회사 알릴아민계 항균첨가제 및 직물항균가공제와 그 제조방법및 직물항균가공방법
CN1315863C (zh) * 2003-12-12 2007-05-16 河南省科学院质量检验与分析测试研究中心 β－L－2'－脱氧－核苷衍生物、其合成方法及其药物用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658672A1 (de) * 1976-12-23 1978-06-29 Robugen Gmbh Neue nucleosid-verbindungen und verfahren zu ihrer herstellung
JPS5535057A (en) * 1978-09-05 1980-03-11 Funai Corp 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it
US4340728A (en) * 1979-11-28 1982-07-20 Fuji Kagaku Kogyo Kabushiki Kaisha Nucleoside derivatives and process for preparing same
DE3002197A1 (de) * 1980-01-22 1981-07-23 Robugen Gmbh Pharmazeutische Fabrik Esslingen A.N., 7300 Esslingen 5-alkylsubstituierte pyrimidin-nukleoside, verfahren zu deren herstellung und daraus hergestellte virostatische und cytostatische mittel
JPS5791994A (en) * 1980-11-26 1982-06-08 Fuji Kagaku Kogyo Kk 5'-o-(n-alkylcarbamoylalanyl)-5-fluorouridine and its preparation
DE3263939D1 (en) * 1981-12-09 1985-07-04 Teijin Ltd 5-fluoro-2'-deoxyuridine derivatives and a process for the preparation thereof
JPS5929699A (ja) * 1982-08-11 1984-02-16 Funai Corp ２′−デオキシ−５−フルオロウリジンのエ−テル誘導体およびその製造方法並びにこれを含有する抗腫瘍剤
EP0129984B1 (en) * 1983-05-23 1988-03-02 Taiho Pharmaceutical Company Limited Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
DE3481191D1 (de) * 1983-07-20 1990-03-08 Teijin Ltd Antineoplastisches mittel.
DE3583726D1 (de) * 1984-10-30 1991-09-12 Otsuka Pharma Co Ltd 5-fluoruracilderivate.
JPS61189292A (ja) * 1985-02-15 1986-08-22 Funai Corp ５−フルオロデオキシウリジン誘導体の新規な固溶体及びこれを活性成分として含有する制癌剤
JPS62187484A (ja) * 1986-02-12 1987-08-15 Taiho Yakuhin Kogyo Kk ３′−０−ベンジル−２′−デオキシ−β−ウリジン類の製造方法
ES2058073T3 (es) * 1986-04-30 1994-11-01 Otsuka Pharma Co Ltd Derivados de 5-fluorouracilo.

Also Published As

Publication number Publication date
EP0301873A3 (en) 1990-11-28
CN1032169A (zh) 1989-04-05
DK423988D0 (da) 1988-07-29
ES2053742T3 (es) 1994-08-01
EP0301873B1 (en) 1994-06-08
CN1022249C (zh) 1993-09-29
AU2002288A (en) 1989-02-02
EP0301873A2 (en) 1989-02-01
DE3889993T2 (de) 1994-09-22
AU610913B2 (en) 1991-05-30
CA1313866C (en) 1993-02-23
FI89497C (fi) 1993-10-11
US4946951A (en) 1990-08-07
ATE106891T1 (de) 1994-06-15
FI89497B (fi) 1993-06-30
DE3889993D1 (de) 1994-07-14
NO883387D0 (no) 1988-07-29
DK423988A (da) 1989-02-01
FI883584A0 (fi) 1988-07-29
NO883387L (no) 1989-02-01
DK171236B1 (da) 1996-08-05
KR890002223A (ko) 1989-04-10

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Legal Events

Date Code Title Description
BB Publication of examined application
PC Transfer of assignment of patent

Owner name: TAIHO PHARMACEUTICAL CO., LTD.

MM Patent lapsed
MM Patent lapsed

Owner name: TAIHO PHARMACEUTICAL CO., LTD.