DK169816B1 - Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne - Google Patents

Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne Download PDF

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Publication number
DK169816B1
DK169816B1 DK492288A DK492288A DK169816B1 DK 169816 B1 DK169816 B1 DK 169816B1 DK 492288 A DK492288 A DK 492288A DK 492288 A DK492288 A DK 492288A DK 169816 B1 DK169816 B1 DK 169816B1
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DK
Denmark
Prior art keywords
lower alkyl
ethoxy
compound
amino
benzyl
Prior art date
Application number
DK492288A
Other languages
Danish (da)
English (en)
Other versions
DK492288D0 (da
DK492288A (da
Inventor
Yasuo Itoh
Hideo Kato
Eiichi Koshinaka
Nobuo Ogawa
Hiroyuki Nishino
Jun Sakaguchi
Original Assignee
Hokuriku Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP62221211A external-priority patent/JPS6466153A/ja
Priority claimed from JP62236250A external-priority patent/JPS6479144A/ja
Priority claimed from JP62242765A external-priority patent/JPS6485960A/ja
Priority claimed from JP62249749A external-priority patent/JPH0193568A/ja
Application filed by Hokuriku Pharmaceutical filed Critical Hokuriku Pharmaceutical
Publication of DK492288D0 publication Critical patent/DK492288D0/da
Publication of DK492288A publication Critical patent/DK492288A/da
Application granted granted Critical
Publication of DK169816B1 publication Critical patent/DK169816B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicinal Preparation (AREA)
  • Hybrid Electric Vehicles (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Catalysts (AREA)
  • Cephalosporin Compounds (AREA)
DK492288A 1987-09-05 1988-09-05 Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne DK169816B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
JP22121187 1987-09-05
JP62221211A JPS6466153A (en) 1987-09-05 1987-09-05 Amide compound and digestive tract motion-activator containing said compound as active ingredient
JP62236250A JPS6479144A (en) 1987-09-22 1987-09-22 Amide compound and agent for promoting motion of digestive tract containing said compound
JP23625087 1987-09-22
JP62242765A JPS6485960A (en) 1987-09-29 1987-09-29 Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient
JP24276587 1987-09-29
JP62249749A JPH0193568A (ja) 1987-10-05 1987-10-05 アミド化合物、及びそれを有効成分とする消化管運動賦活剤
JP24974987 1987-10-05

Publications (3)

Publication Number Publication Date
DK492288D0 DK492288D0 (da) 1988-09-05
DK492288A DK492288A (da) 1989-03-06
DK169816B1 true DK169816B1 (da) 1995-03-06

Family

ID=27476995

Family Applications (1)

Application Number Title Priority Date Filing Date
DK492288A DK169816B1 (da) 1987-09-05 1988-09-05 Amidforbindelser, farmaceutisk præparat indeholdende samme samt fremgangsmåde til fremstilling af forbindelserne

Country Status (15)

Country Link
US (1) US4983633A (ko)
EP (1) EP0306827B1 (ko)
KR (1) KR940000058B1 (ko)
AT (1) ATE66913T1 (ko)
AU (1) AU606988B2 (ko)
BG (1) BG48932A3 (ko)
CA (1) CA1335101C (ko)
DE (1) DE3864636D1 (ko)
DK (1) DK169816B1 (ko)
ES (1) ES2037779T3 (ko)
FI (1) FI87644C (ko)
HU (1) HU198447B (ko)
SU (1) SU1627082A3 (ko)
UA (1) UA6330A1 (ko)
YU (1) YU46706B (ko)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2186623A1 (en) * 1994-03-30 1995-10-21 Takeshi Kawakita Benzoic acid compound and use thereof as medicine
US5864039A (en) * 1994-03-30 1999-01-26 Yoshitomi Pharmaceutical Industries, Ltd. Benzoic acid compounds and use thereof as medicaments
KR0147963B1 (ko) * 1995-01-10 1998-08-17 강박광 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법
AU1180400A (en) * 1998-11-16 2000-06-05 Hokuriku Seiyaku Co. Ltd Remedies for digestive tract functional disorder
JP3853653B2 (ja) 1999-08-07 2006-12-06 ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト カルボン酸アミド、その調製法及び医薬組成物としてのその使用
DE10235312A1 (de) 2002-08-01 2004-02-12 Basf Ag Verfahren zur Herstellung von Aminoalkoxybenzylaminen und Aminoalkoxybenzonitrilen als Zwischenprodukte
CN1305837C (zh) * 2004-06-11 2007-03-21 吉林修正药业新药研发中心 一种改进的伊托必利原料药的制备方法
KR100595117B1 (ko) * 2004-07-28 2006-06-30 일양약품주식회사 이토프라이드·염산염 중간체인4-[2-(디메틸아미노)에톡시]벤질아민의 새로운 제조방법
ITMI20042168A1 (it) * 2004-11-12 2005-02-12 Erregierre Spa Processo di preparazione di itopride cloridrato
KR100663167B1 (ko) * 2005-10-27 2007-01-02 동우신테크 주식회사 염산 이토프리드의 제조방법
WO2007074386A2 (en) * 2005-12-28 2007-07-05 Bakulesh Mafatlal Khamar A novel process for synthesis of itopride and it’s novel intermediate-n-(4-hydroxybenzyl)-3,4-dimethoxybenzamide
KR100836528B1 (ko) * 2007-07-25 2008-06-10 주식회사 휴온스 이토프리드 염산염의 제조방법
CN101967103A (zh) * 2010-09-28 2011-02-09 浙江金伯士药业有限公司 一种伊托必利中间体的制备新方法
CN103073446B (zh) * 2011-10-26 2014-12-24 珠海保税区丽珠合成制药有限公司 盐酸伊托必利的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1069640B (de) * 1959-11-26 F. Hoffmann-La Roche S. Co. Aktiengesellschaft, Basel (Schweiz) Verfahren zur Herstellung von anfemetisch wirksamen Benzylaminderivaten
FR1525M (fr) * 1961-07-25 1962-11-16 Ile De France Médicaments antiémétiques nouveaux.
NL130752C (ko) * 1964-05-07

Also Published As

Publication number Publication date
UA6330A1 (uk) 1994-12-29
FI884077A (fi) 1989-03-06
HUT47531A (en) 1989-03-28
DK492288D0 (da) 1988-09-05
FI87644C (fi) 1993-02-10
DE3864636D1 (de) 1991-10-10
SU1627082A3 (ru) 1991-02-07
KR940000058B1 (ko) 1994-01-05
DK492288A (da) 1989-03-06
AU2186288A (en) 1989-03-09
ATE66913T1 (de) 1991-09-15
FI87644B (fi) 1992-10-30
US4983633A (en) 1991-01-08
YU160088A (en) 1990-06-30
CA1335101C (en) 1995-04-04
HU198447B (en) 1989-10-30
EP0306827B1 (en) 1991-09-04
AU606988B2 (en) 1991-02-21
YU46706B (sh) 1994-04-05
ES2037779T3 (es) 1993-07-01
KR890005036A (ko) 1989-05-11
FI884077A0 (fi) 1988-09-05
EP0306827A1 (en) 1989-03-15
BG48932A3 (en) 1991-06-14

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Date Code Title Description
B1 Patent granted (law 1993)
PUP Patent expired