JPS6485960A - Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient - Google Patents
Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredientInfo
- Publication number
- JPS6485960A JPS6485960A JP62242765A JP24276587A JPS6485960A JP S6485960 A JPS6485960 A JP S6485960A JP 62242765 A JP62242765 A JP 62242765A JP 24276587 A JP24276587 A JP 24276587A JP S6485960 A JPS6485960 A JP S6485960A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- motion
- compound
- digestive tube
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound shown by formula I (R1 and R2 are H or lower alkyl; R3 and R4 are H, lower alkoxy, amino or halogen; R5 and R6 are lower alkyl or R5 and R6 together with N are bonded to form 1-pyrrolidinyl or piperidino) and an acid addition salt thereof. EXAMPLE:N-{ 4-(2-(Dimethylamino) ethoxy]benzyl }-2-methoxy-5-sulfamoylbenza mide. USE:A reactivator for motion of digestive tube having excellent activating action on digestive tube, useful for improving various indefinite complaint symptoms followed by reduction in motion function of gastrointestinal tract. PREPARATION:A carboxylic acid shown by formula II is converted into a reactive derivative thereof (acid chloride, acid anhydride or mixed acid anhy dride) and reacted with an amine shown by formula III including a novel com pound in the presence or absence of a base (e.g. pyridine or picoline) in an inert organic solvent (e.g. ether or benzene) to give a compound shown by formula I.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62242765A JPS6485960A (en) | 1987-09-29 | 1987-09-29 | Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient |
YU160088A YU46706B (en) | 1987-09-05 | 1988-08-19 | PROCEDURE FOR OBTAINING AMIDE COMPOUNDS |
CA000576117A CA1335101C (en) | 1987-09-05 | 1988-08-30 | Benzamide compounds, process for preparing the same, and compositions for activating gastric motor function containing the same |
EP88114257A EP0306827B1 (en) | 1987-09-05 | 1988-09-01 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
ES198888114257T ES2037779T3 (en) | 1987-09-05 | 1988-09-01 | PROCEDURE FOR PREPARING NEW AMIDA COMPOUNDS. |
DE8888114257T DE3864636D1 (en) | 1987-09-05 | 1988-09-01 | AMID COMPOUNDS, METHOD FOR THEIR PRODUCTION AND COMPOSITION FOR THE ACTIVATION OF GASTROMOTORIC FUNCTIONS. |
AT88114257T ATE66913T1 (en) | 1987-09-05 | 1988-09-01 | AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND COMPOSITION FOR ACTIVATING GASTROMOTOR FUNCTIONS. |
BG85365A BG48932A3 (en) | 1987-09-05 | 1988-09-02 | Method for preparing of amide compounds |
HU884538A HU198447B (en) | 1987-09-05 | 1988-09-02 | Process for production of derivatives of amid and medical compositions containing them |
SU4356531A SU1627082A3 (en) | 1987-09-05 | 1988-09-02 | Process for preparation benzamide derivatives |
US07/241,028 US4983633A (en) | 1987-09-05 | 1988-09-02 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
UA4356531A UA6330A1 (en) | 1987-09-05 | 1988-09-02 | Process for the preparation of benzamide derivatives |
KR1019880011317A KR940000058B1 (en) | 1987-09-05 | 1988-09-02 | Amide campounds, process for preparing the same and composition for activating gastric motor function containing the same |
FI884077A FI87644C (en) | 1987-09-05 | 1988-09-05 | FRAMEWORK FOR PHARMACEUTICAL FRAMEWORK |
DK492288A DK169816B1 (en) | 1987-09-05 | 1988-09-05 | Amide compounds, pharmaceutical composition containing the same as well as process for the preparation of the compounds |
AU21862/88A AU606988B2 (en) | 1987-09-05 | 1988-09-05 | Novel amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62242765A JPS6485960A (en) | 1987-09-29 | 1987-09-29 | Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6485960A true JPS6485960A (en) | 1989-03-30 |
Family
ID=17093942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62242765A Pending JPS6485960A (en) | 1987-09-05 | 1987-09-29 | Amide compound and reactivator for motion of digestive tube comprising said compound as active ingredient |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6485960A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100595117B1 (en) * | 2004-07-28 | 2006-06-30 | 일양약품주식회사 | Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates |
-
1987
- 1987-09-29 JP JP62242765A patent/JPS6485960A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100595117B1 (en) * | 2004-07-28 | 2006-06-30 | 일양약품주식회사 | Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates |
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