JPS6483065A - Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent - Google Patents
Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agentInfo
- Publication number
- JPS6483065A JPS6483065A JP24186887A JP24186887A JPS6483065A JP S6483065 A JPS6483065 A JP S6483065A JP 24186887 A JP24186887 A JP 24186887A JP 24186887 A JP24186887 A JP 24186887A JP S6483065 A JPS6483065 A JP S6483065A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- endo
- antiarhythmic
- cyclopropylene
- cis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formula I [X is 2-5C alkylene or group of formula II; Y is dialkylamino or group of formula III-formula V; Z is H (the dotted line is C-C bond) or halogen (the dotted line is not C-C bond)] and its acid addition salt. EXAMPLE:N-beta-dimethylaminoethyl endo-cis-3,6-endo cyclopropylene-DELTA<4>-tetrahydro- 1,2-phthalic acid amide. USE:A drug having antiarhythmic action, bronchodilating action, anticholine action and muscle relaxing action. PREPARATION:A compound of formula I wherein Z is H can be produced e.g. by reacting 3,6-endocyclopropylene-DELTA<4>-tetrahydrophthalic anhydride with an amine of formula H2N-X-Y.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24186887A JPS6483065A (en) | 1987-09-25 | 1987-09-25 | Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24186887A JPS6483065A (en) | 1987-09-25 | 1987-09-25 | Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6483065A true JPS6483065A (en) | 1989-03-28 |
Family
ID=17080720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP24186887A Pending JPS6483065A (en) | 1987-09-25 | 1987-09-25 | Endo-cis-3,6-cyclopropylene-tetra(or hexa)hydrophthalic acid imide derivative and antiarhythmic agent |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6483065A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004723A1 (en) * | 1993-08-04 | 1995-02-16 | Yamanouchi Pharmaceutical Co., Ltd. | Imidazolylalkylamine derivative and pharmaceutical composition thereof |
| JP2007521273A (en) * | 2003-06-20 | 2007-08-02 | シガ テクノロジーズ，インコーポレーテッド | Compounds, compositions and methods for treating and preventing orthopoxvirus infection and related diseases |
-
1987
- 1987-09-25 JP JP24186887A patent/JPS6483065A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995004723A1 (en) * | 1993-08-04 | 1995-02-16 | Yamanouchi Pharmaceutical Co., Ltd. | Imidazolylalkylamine derivative and pharmaceutical composition thereof |
| JP2007521273A (en) * | 2003-06-20 | 2007-08-02 | シガ テクノロジーズ，インコーポレーテッド | Compounds, compositions and methods for treating and preventing orthopoxvirus infection and related diseases |
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