JPS6479144A - Amide compound and agent for promoting motion of digestive tract containing said compound - Google Patents
Amide compound and agent for promoting motion of digestive tract containing said compoundInfo
- Publication number
- JPS6479144A JPS6479144A JP62236250A JP23625087A JPS6479144A JP S6479144 A JPS6479144 A JP S6479144A JP 62236250 A JP62236250 A JP 62236250A JP 23625087 A JP23625087 A JP 23625087A JP S6479144 A JPS6479144 A JP S6479144A
- Authority
- JP
- Japan
- Prior art keywords
- compound
- agent
- formula
- motion
- tracts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The compound of formula I (R1 and R2 are lower alkyl or together with N form 1-pyrrolidinyl or piperidino). EXAMPLE:4-Amino-5-chloro-N-[4-[2-(dimethylamino) ethoxy] benzyl]-2-methoxy benzamide. USE:An agent for promoting the motion of digestive tracts. It has excellent activ ity to promote the motion of digestive tracts and is extremely useful as an agent for ameliorating various indefinite complaint symptoms of digestive tracts caused by the lowering of the mobility of gastroenteric tracts. PREPARATION:The objective compound of formula I can be produced by converting a carboxylic acid compound of formula II into its reactive derivative and reacting with an amine compound of formula III in the presence or absence of a base (e.g., triethylamine) in a solvent (e.g., chloroform) at a temperature between 0 deg.C and the refluxing temperature of the solvent.
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62236250A JPS6479144A (en) | 1987-09-22 | 1987-09-22 | Amide compound and agent for promoting motion of digestive tract containing said compound |
YU160088A YU46706B (en) | 1987-09-05 | 1988-08-19 | PROCEDURE FOR OBTAINING AMIDE COMPOUNDS |
CA000576117A CA1335101C (en) | 1987-09-05 | 1988-08-30 | Benzamide compounds, process for preparing the same, and compositions for activating gastric motor function containing the same |
ES198888114257T ES2037779T3 (en) | 1987-09-05 | 1988-09-01 | PROCEDURE FOR PREPARING NEW AMIDA COMPOUNDS. |
DE8888114257T DE3864636D1 (en) | 1987-09-05 | 1988-09-01 | AMID COMPOUNDS, METHOD FOR THEIR PRODUCTION AND COMPOSITION FOR THE ACTIVATION OF GASTROMOTORIC FUNCTIONS. |
AT88114257T ATE66913T1 (en) | 1987-09-05 | 1988-09-01 | AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND COMPOSITION FOR ACTIVATING GASTROMOTOR FUNCTIONS. |
EP88114257A EP0306827B1 (en) | 1987-09-05 | 1988-09-01 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
US07/241,028 US4983633A (en) | 1987-09-05 | 1988-09-02 | Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
BG85365A BG48932A3 (en) | 1987-09-05 | 1988-09-02 | Method for preparing of amide compounds |
HU884538A HU198447B (en) | 1987-09-05 | 1988-09-02 | Process for production of derivatives of amid and medical compositions containing them |
SU4356531A SU1627082A3 (en) | 1987-09-05 | 1988-09-02 | Process for preparation benzamide derivatives |
UA4356531A UA6330A1 (en) | 1987-09-05 | 1988-09-02 | Process for the preparation of benzamide derivatives |
KR1019880011317A KR940000058B1 (en) | 1987-09-05 | 1988-09-02 | Amide campounds, process for preparing the same and composition for activating gastric motor function containing the same |
FI884077A FI87644C (en) | 1987-09-05 | 1988-09-05 | FRAMEWORK FOR PHARMACEUTICAL FRAMEWORK |
DK492288A DK169816B1 (en) | 1987-09-05 | 1988-09-05 | Amide compounds, pharmaceutical composition containing the same as well as process for the preparation of the compounds |
AU21862/88A AU606988B2 (en) | 1987-09-05 | 1988-09-05 | Novel amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62236250A JPS6479144A (en) | 1987-09-22 | 1987-09-22 | Amide compound and agent for promoting motion of digestive tract containing said compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6479144A true JPS6479144A (en) | 1989-03-24 |
Family
ID=16997998
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62236250A Pending JPS6479144A (en) | 1987-09-05 | 1987-09-22 | Amide compound and agent for promoting motion of digestive tract containing said compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6479144A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100595117B1 (en) * | 2004-07-28 | 2006-06-30 | 일양약품주식회사 | Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates |
-
1987
- 1987-09-22 JP JP62236250A patent/JPS6479144A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR100595117B1 (en) * | 2004-07-28 | 2006-06-30 | 일양약품주식회사 | Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates |
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