JPS6479144A - Amide compound and agent for promoting motion of digestive tract containing said compound - Google Patents

Amide compound and agent for promoting motion of digestive tract containing said compound

Info

Publication number
JPS6479144A
JPS6479144A JP62236250A JP23625087A JPS6479144A JP S6479144 A JPS6479144 A JP S6479144A JP 62236250 A JP62236250 A JP 62236250A JP 23625087 A JP23625087 A JP 23625087A JP S6479144 A JPS6479144 A JP S6479144A
Authority
JP
Japan
Prior art keywords
compound
agent
formula
motion
tracts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62236250A
Other languages
Japanese (ja)
Inventor
Yasuo Ito
Hideo Kato
Eiichi Ecchu
Nobuo Ogawa
Hiroyuki Nishino
Jun Sakaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Japan Co Ltd
Original Assignee
Hokuriku Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hokuriku Pharmaceutical Co Ltd filed Critical Hokuriku Pharmaceutical Co Ltd
Priority to JP62236250A priority Critical patent/JPS6479144A/en
Priority to YU160088A priority patent/YU46706B/en
Priority to CA000576117A priority patent/CA1335101C/en
Priority to ES198888114257T priority patent/ES2037779T3/en
Priority to DE8888114257T priority patent/DE3864636D1/en
Priority to AT88114257T priority patent/ATE66913T1/en
Priority to EP88114257A priority patent/EP0306827B1/en
Priority to US07/241,028 priority patent/US4983633A/en
Priority to BG85365A priority patent/BG48932A3/en
Priority to HU884538A priority patent/HU198447B/en
Priority to SU4356531A priority patent/SU1627082A3/en
Priority to UA4356531A priority patent/UA6330A1/en
Priority to KR1019880011317A priority patent/KR940000058B1/en
Priority to FI884077A priority patent/FI87644C/en
Priority to DK492288A priority patent/DK169816B1/en
Priority to AU21862/88A priority patent/AU606988B2/en
Publication of JPS6479144A publication Critical patent/JPS6479144A/en
Pending legal-status Critical Current

Links

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The compound of formula I (R1 and R2 are lower alkyl or together with N form 1-pyrrolidinyl or piperidino). EXAMPLE:4-Amino-5-chloro-N-[4-[2-(dimethylamino) ethoxy] benzyl]-2-methoxy benzamide. USE:An agent for promoting the motion of digestive tracts. It has excellent activ ity to promote the motion of digestive tracts and is extremely useful as an agent for ameliorating various indefinite complaint symptoms of digestive tracts caused by the lowering of the mobility of gastroenteric tracts. PREPARATION:The objective compound of formula I can be produced by converting a carboxylic acid compound of formula II into its reactive derivative and reacting with an amine compound of formula III in the presence or absence of a base (e.g., triethylamine) in a solvent (e.g., chloroform) at a temperature between 0 deg.C and the refluxing temperature of the solvent.
JP62236250A 1987-09-05 1987-09-22 Amide compound and agent for promoting motion of digestive tract containing said compound Pending JPS6479144A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
JP62236250A JPS6479144A (en) 1987-09-22 1987-09-22 Amide compound and agent for promoting motion of digestive tract containing said compound
YU160088A YU46706B (en) 1987-09-05 1988-08-19 PROCEDURE FOR OBTAINING AMIDE COMPOUNDS
CA000576117A CA1335101C (en) 1987-09-05 1988-08-30 Benzamide compounds, process for preparing the same, and compositions for activating gastric motor function containing the same
ES198888114257T ES2037779T3 (en) 1987-09-05 1988-09-01 PROCEDURE FOR PREPARING NEW AMIDA COMPOUNDS.
DE8888114257T DE3864636D1 (en) 1987-09-05 1988-09-01 AMID COMPOUNDS, METHOD FOR THEIR PRODUCTION AND COMPOSITION FOR THE ACTIVATION OF GASTROMOTORIC FUNCTIONS.
AT88114257T ATE66913T1 (en) 1987-09-05 1988-09-01 AMIDE COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND COMPOSITION FOR ACTIVATING GASTROMOTOR FUNCTIONS.
EP88114257A EP0306827B1 (en) 1987-09-05 1988-09-01 Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same
US07/241,028 US4983633A (en) 1987-09-05 1988-09-02 Amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same
BG85365A BG48932A3 (en) 1987-09-05 1988-09-02 Method for preparing of amide compounds
HU884538A HU198447B (en) 1987-09-05 1988-09-02 Process for production of derivatives of amid and medical compositions containing them
SU4356531A SU1627082A3 (en) 1987-09-05 1988-09-02 Process for preparation benzamide derivatives
UA4356531A UA6330A1 (en) 1987-09-05 1988-09-02 Process for the preparation of benzamide derivatives
KR1019880011317A KR940000058B1 (en) 1987-09-05 1988-09-02 Amide campounds, process for preparing the same and composition for activating gastric motor function containing the same
FI884077A FI87644C (en) 1987-09-05 1988-09-05 FRAMEWORK FOR PHARMACEUTICAL FRAMEWORK
DK492288A DK169816B1 (en) 1987-09-05 1988-09-05 Amide compounds, pharmaceutical composition containing the same as well as process for the preparation of the compounds
AU21862/88A AU606988B2 (en) 1987-09-05 1988-09-05 Novel amide compounds, process for preparing the same, and composition for activating gastric motor function containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62236250A JPS6479144A (en) 1987-09-22 1987-09-22 Amide compound and agent for promoting motion of digestive tract containing said compound

Publications (1)

Publication Number Publication Date
JPS6479144A true JPS6479144A (en) 1989-03-24

Family

ID=16997998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62236250A Pending JPS6479144A (en) 1987-09-05 1987-09-22 Amide compound and agent for promoting motion of digestive tract containing said compound

Country Status (1)

Country Link
JP (1) JPS6479144A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100595117B1 (en) * 2004-07-28 2006-06-30 일양약품주식회사 Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100595117B1 (en) * 2004-07-28 2006-06-30 일양약품주식회사 Process for Preparing 4-[2-DimethylaminoEthoxy]Benzylamine of Itopride·HCl Mediates

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