JPS55115889A - 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation - Google Patents
6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparationInfo
- Publication number
- JPS55115889A JPS55115889A JP2193779A JP2193779A JPS55115889A JP S55115889 A JPS55115889 A JP S55115889A JP 2193779 A JP2193779 A JP 2193779A JP 2193779 A JP2193779 A JP 2193779A JP S55115889 A JPS55115889 A JP S55115889A
- Authority
- JP
- Japan
- Prior art keywords
- agent
- compound
- carbamoylthiazolo
- pyrimidine derivative
- reacting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A pyrimidine derivative of formula I (R<1>,<2> are H, (substituted) alkyl, phenyl, heterocyclic group, cycloalkyl, etc.). EXAMPLE:5H-5-Oxo-6-carbamoylthiazolo[3,2-a]pyrimidine. USE:Antiphlogistic agent, antipyretic agent, blood platelet coagulation inhibiting agent, immuno-regulating agent, etc. Synthetic intermediate of various pharmacologically active substances. PROCESS:The compound of formula I is prepared, e.g. by reacting an acid halide or mixed acid anhydride of a compound II with an amine III in a solvent such as ether, THF, etc., optionally in the presence of a base, or by reacting the compound II with the compound III in the presence of a condensing agent.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2193779A JPS55115889A (en) | 1979-02-28 | 1979-02-28 | 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2193779A JPS55115889A (en) | 1979-02-28 | 1979-02-28 | 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55115889A true JPS55115889A (en) | 1980-09-06 |
JPS6233239B2 JPS6233239B2 (en) | 1987-07-20 |
Family
ID=12068952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2193779A Granted JPS55115889A (en) | 1979-02-28 | 1979-02-28 | 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55115889A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2520742A1 (en) * | 1982-02-04 | 1983-08-05 | Erba Farmitalia | SUBSTITUTED 1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINES USEFUL AS MEDICAMENTS AND PROCESS FOR THEIR PREPARATION |
US4421914A (en) * | 1980-10-15 | 1983-12-20 | Teijin Limited | Thiazolo[3,2-a]pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof |
FR2538392A1 (en) * | 1982-12-23 | 1984-06-29 | Erba Farmitalia | CARBOXAMIDO TYPE DERIVATIVES OF 5H-1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND EXHIBITING AN ANALGESIC AND ANTI-INFLAMMATORY EFFECT |
-
1979
- 1979-02-28 JP JP2193779A patent/JPS55115889A/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4421914A (en) * | 1980-10-15 | 1983-12-20 | Teijin Limited | Thiazolo[3,2-a]pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof |
FR2520742A1 (en) * | 1982-02-04 | 1983-08-05 | Erba Farmitalia | SUBSTITUTED 1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINES USEFUL AS MEDICAMENTS AND PROCESS FOR THEIR PREPARATION |
FR2538392A1 (en) * | 1982-12-23 | 1984-06-29 | Erba Farmitalia | CARBOXAMIDO TYPE DERIVATIVES OF 5H-1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND EXHIBITING AN ANALGESIC AND ANTI-INFLAMMATORY EFFECT |
Also Published As
Publication number | Publication date |
---|---|
JPS6233239B2 (en) | 1987-07-20 |
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