JPS55115889A - 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation - Google Patents

6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation

Info

Publication number
JPS55115889A
JPS55115889A JP2193779A JP2193779A JPS55115889A JP S55115889 A JPS55115889 A JP S55115889A JP 2193779 A JP2193779 A JP 2193779A JP 2193779 A JP2193779 A JP 2193779A JP S55115889 A JPS55115889 A JP S55115889A
Authority
JP
Japan
Prior art keywords
agent
compound
carbamoylthiazolo
pyrimidine derivative
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2193779A
Other languages
Japanese (ja)
Other versions
JPS6233239B2 (en
Inventor
Kenzo Watanabe
Takeo Oba
Toshio Tanaka
Kiyoshi Sakauchi
Noriaki Okamura
Tatsuyuki Naritomo
Seiji Kurozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP2193779A priority Critical patent/JPS55115889A/en
Publication of JPS55115889A publication Critical patent/JPS55115889A/en
Publication of JPS6233239B2 publication Critical patent/JPS6233239B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A pyrimidine derivative of formula I (R<1>,<2> are H, (substituted) alkyl, phenyl, heterocyclic group, cycloalkyl, etc.). EXAMPLE:5H-5-Oxo-6-carbamoylthiazolo[3,2-a]pyrimidine. USE:Antiphlogistic agent, antipyretic agent, blood platelet coagulation inhibiting agent, immuno-regulating agent, etc. Synthetic intermediate of various pharmacologically active substances. PROCESS:The compound of formula I is prepared, e.g. by reacting an acid halide or mixed acid anhydride of a compound II with an amine III in a solvent such as ether, THF, etc., optionally in the presence of a base, or by reacting the compound II with the compound III in the presence of a condensing agent.
JP2193779A 1979-02-28 1979-02-28 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation Granted JPS55115889A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2193779A JPS55115889A (en) 1979-02-28 1979-02-28 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2193779A JPS55115889A (en) 1979-02-28 1979-02-28 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS55115889A true JPS55115889A (en) 1980-09-06
JPS6233239B2 JPS6233239B2 (en) 1987-07-20

Family

ID=12068952

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2193779A Granted JPS55115889A (en) 1979-02-28 1979-02-28 6-carbamoylthiazolo 3,2-a pyrimidine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS55115889A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2520742A1 (en) * 1982-02-04 1983-08-05 Erba Farmitalia SUBSTITUTED 1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINES USEFUL AS MEDICAMENTS AND PROCESS FOR THEIR PREPARATION
US4421914A (en) * 1980-10-15 1983-12-20 Teijin Limited Thiazolo[3,2-a]pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof
FR2538392A1 (en) * 1982-12-23 1984-06-29 Erba Farmitalia CARBOXAMIDO TYPE DERIVATIVES OF 5H-1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND EXHIBITING AN ANALGESIC AND ANTI-INFLAMMATORY EFFECT

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4421914A (en) * 1980-10-15 1983-12-20 Teijin Limited Thiazolo[3,2-a]pyrimidines, derivatives thereof, processes for production thereof, and pharmaceutical use thereof
FR2520742A1 (en) * 1982-02-04 1983-08-05 Erba Farmitalia SUBSTITUTED 1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINES USEFUL AS MEDICAMENTS AND PROCESS FOR THEIR PREPARATION
FR2538392A1 (en) * 1982-12-23 1984-06-29 Erba Farmitalia CARBOXAMIDO TYPE DERIVATIVES OF 5H-1,3,4-THIADIAZOLO (3,2-A) PYRIMIDINE, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND EXHIBITING AN ANALGESIC AND ANTI-INFLAMMATORY EFFECT

Also Published As

Publication number Publication date
JPS6233239B2 (en) 1987-07-20

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