JPS5551068A - Novel hydantoin derivative, and antiphlogistic analgesic agent containing the same - Google Patents

Novel hydantoin derivative, and antiphlogistic analgesic agent containing the same

Info

Publication number
JPS5551068A
JPS5551068A JP12433178A JP12433178A JPS5551068A JP S5551068 A JPS5551068 A JP S5551068A JP 12433178 A JP12433178 A JP 12433178A JP 12433178 A JP12433178 A JP 12433178A JP S5551068 A JPS5551068 A JP S5551068A
Authority
JP
Japan
Prior art keywords
analgesic agent
hydantoin derivative
same
agent containing
antiphlogistic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12433178A
Other languages
Japanese (ja)
Other versions
JPS6019731B2 (en
Inventor
Masayuki Teranishi
Yoshihiro Nakamizo
Yoshio Nakamura
Takiyuki Hirayama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP12433178A priority Critical patent/JPS6019731B2/en
Publication of JPS5551068A publication Critical patent/JPS5551068A/en
Publication of JPS6019731B2 publication Critical patent/JPS6019731B2/en
Expired legal-status Critical Current

Links

Abstract

NEW MATERIAL:A hydantoin derivative of formula I [X is O or S; Ar is pheyl which may be substituted with halogen, alkyl, etc. R is alkyl, (substituted) cycloalkyl, aryl, or aralkyl].
EXAMPLE: 1-Ethyoxycarbonyl-3(3,4-dichlorophenyl)-5-methylhydantoin.
USE: An antiphlogistic, analgesic agent having analgesic and muscule-relaxing activities as well as strong antiphlogistic activity, and extremely low toxicity and side effects.
PROCESS: The compound I is prepared by the condensation reaction of a compound II with a compound III (Hal is halogen) in an organic solvent, in the presence of an organic base.
COPYRIGHT: (C)1980,JPO&Japio
JP12433178A 1978-10-09 1978-10-09 anti-inflammatory analgesic Expired JPS6019731B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12433178A JPS6019731B2 (en) 1978-10-09 1978-10-09 anti-inflammatory analgesic

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12433178A JPS6019731B2 (en) 1978-10-09 1978-10-09 anti-inflammatory analgesic

Publications (2)

Publication Number Publication Date
JPS5551068A true JPS5551068A (en) 1980-04-14
JPS6019731B2 JPS6019731B2 (en) 1985-05-17

Family

ID=14882682

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12433178A Expired JPS6019731B2 (en) 1978-10-09 1978-10-09 anti-inflammatory analgesic

Country Status (1)

Country Link
JP (1) JPS6019731B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297461A (en) * 1991-03-27 1992-10-21 Otsuka Pharmaceut Factory Inc 2-thiohydantoin derivative
EP0894497A1 (en) * 1997-07-31 1999-02-03 Grünenthal GmbH Use of substituted imidazolidin-2,4-diones as analgesics

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04297461A (en) * 1991-03-27 1992-10-21 Otsuka Pharmaceut Factory Inc 2-thiohydantoin derivative
EP0894497A1 (en) * 1997-07-31 1999-02-03 Grünenthal GmbH Use of substituted imidazolidin-2,4-diones as analgesics

Also Published As

Publication number Publication date
JPS6019731B2 (en) 1985-05-17

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