JPS5551068A - Novel hydantoin derivative, and antiphlogistic analgesic agent containing the same - Google Patents
Novel hydantoin derivative, and antiphlogistic analgesic agent containing the sameInfo
- Publication number
- JPS5551068A JPS5551068A JP12433178A JP12433178A JPS5551068A JP S5551068 A JPS5551068 A JP S5551068A JP 12433178 A JP12433178 A JP 12433178A JP 12433178 A JP12433178 A JP 12433178A JP S5551068 A JPS5551068 A JP S5551068A
- Authority
- JP
- Japan
- Prior art keywords
- analgesic agent
- hydantoin derivative
- same
- agent containing
- antiphlogistic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A hydantoin derivative of formula I [X is O or S; Ar is pheyl which may be substituted with halogen, alkyl, etc. R is alkyl, (substituted) cycloalkyl, aryl, or aralkyl].
EXAMPLE: 1-Ethyoxycarbonyl-3(3,4-dichlorophenyl)-5-methylhydantoin.
USE: An antiphlogistic, analgesic agent having analgesic and muscule-relaxing activities as well as strong antiphlogistic activity, and extremely low toxicity and side effects.
PROCESS: The compound I is prepared by the condensation reaction of a compound II with a compound III (Hal is halogen) in an organic solvent, in the presence of an organic base.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12433178A JPS6019731B2 (en) | 1978-10-09 | 1978-10-09 | anti-inflammatory analgesic |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12433178A JPS6019731B2 (en) | 1978-10-09 | 1978-10-09 | anti-inflammatory analgesic |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5551068A true JPS5551068A (en) | 1980-04-14 |
JPS6019731B2 JPS6019731B2 (en) | 1985-05-17 |
Family
ID=14882682
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12433178A Expired JPS6019731B2 (en) | 1978-10-09 | 1978-10-09 | anti-inflammatory analgesic |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6019731B2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04297461A (en) * | 1991-03-27 | 1992-10-21 | Otsuka Pharmaceut Factory Inc | 2-thiohydantoin derivative |
EP0894497A1 (en) * | 1997-07-31 | 1999-02-03 | Grünenthal GmbH | Use of substituted imidazolidin-2,4-diones as analgesics |
-
1978
- 1978-10-09 JP JP12433178A patent/JPS6019731B2/en not_active Expired
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04297461A (en) * | 1991-03-27 | 1992-10-21 | Otsuka Pharmaceut Factory Inc | 2-thiohydantoin derivative |
EP0894497A1 (en) * | 1997-07-31 | 1999-02-03 | Grünenthal GmbH | Use of substituted imidazolidin-2,4-diones as analgesics |
Also Published As
Publication number | Publication date |
---|---|
JPS6019731B2 (en) | 1985-05-17 |
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