DK162233C - Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii - Google Patents
Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viiiInfo
- Publication number
- DK162233C DK162233C DK562189A DK562189A DK162233C DK 162233 C DK162233 C DK 162233C DK 562189 A DK562189 A DK 562189A DK 562189 A DK562189 A DK 562189A DK 162233 C DK162233 C DK 162233C
- Authority
- DK
- Denmark
- Prior art keywords
- viii
- blood plasma
- phatar
- factor viii
- procedure
- Prior art date
Links
- 229960000301 factor viii Drugs 0.000 title abstract 3
- 210000002381 plasma Anatomy 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 102000001690 Factor VIII Human genes 0.000 abstract 2
- 108010054218 Factor VIII Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 238000002523 gelfiltration Methods 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Amplifiers (AREA)
- Networks Using Active Elements (AREA)
- Housing For Livestock And Birds (AREA)
- Cephalosporin Compounds (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Separation By Low-Temperature Treatments (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (28)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK562189A DK162233C (da) | 1989-11-09 | 1989-11-09 | Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii |
ZA908599A ZA908599B (en) | 1989-11-09 | 1990-10-26 | A method for isolating biologically active compounds |
CS905371A CZ537190A3 (cs) | 1989-11-09 | 1990-11-01 | Způsob izolování faktoru VIII |
SK5371-90A SK537190A3 (en) | 1989-11-09 | 1990-11-01 | Method of the factor viii isolation |
ES90917201T ES2068404T3 (es) | 1989-11-09 | 1990-11-05 | Un metodo para aislar el factor viii. |
CA002073012A CA2073012C (fr) | 1989-11-09 | 1990-11-05 | Methode d'isolement du facteur viii |
DE69017050T DE69017050T2 (de) | 1989-11-09 | 1990-11-05 | Verfahren zur isolierung von faktor viii. |
UA94020494A UA29421C2 (uk) | 1989-11-09 | 1990-11-05 | Спосіб виділення фактора vііі з інших білків в плазмі крові |
JP3500067A JP2509407B2 (ja) | 1989-11-09 | 1990-11-05 | 生物学的に活性な化合物の単離方法 |
AU67470/90A AU631471B2 (en) | 1989-11-09 | 1990-11-05 | A method for isolating factor viii |
PCT/DK1990/000279 WO1991007438A1 (fr) | 1989-11-09 | 1990-11-05 | Procede d'isolation du facteur viii |
AT90917201T ATE118508T1 (de) | 1989-11-09 | 1990-11-05 | Verfahren zur isolierung von faktor viii. |
HU9201551A HU214905B (hu) | 1989-11-09 | 1990-11-05 | Eljárás VIII. faktor izolálására |
EP90917201A EP0524172B1 (fr) | 1989-11-09 | 1990-11-05 | Procede d'isolation du facteur viii |
SU905052211A RU2055593C1 (ru) | 1989-11-09 | 1990-11-05 | Способ выделения фактора viii из других белков в плазме крови |
NZ236004A NZ236004A (en) | 1989-11-09 | 1990-11-07 | Isolation of factor viii using gel filtration |
US07/610,480 US5245014A (en) | 1989-11-09 | 1990-11-07 | Method for isolating factors viii from plasma by gel filtration chromatography under group separation conditions |
YU210590A YU47524B (sh) | 1989-11-09 | 1990-11-07 | Postupak za izolovanje faktora viii iz drugih proteina u krvnoj plazmi |
SI9012105A SI9012105A (sl) | 1989-11-09 | 1990-11-07 | Postopek za izoliranje biološko aktivnih spoji |
IE402290A IE66836B1 (en) | 1989-11-09 | 1990-11-08 | A method for isolating biologically active compounds |
IL9627790A IL96277A (en) | 1989-11-09 | 1990-11-08 | Method for isolating factor IIIV |
PT95830A PT95830B (pt) | 1989-11-09 | 1990-11-08 | Processo para o isolamento do factor viii sob a forma de uma fraccao pura directamente de plasma mediante filtracao em gel |
CN90109030A CN1044121C (zh) | 1989-11-09 | 1990-11-09 | 分离凝血因子viii配合物的方法 |
PL90287703A PL164894B1 (pl) | 1989-11-09 | 1990-11-09 | Sposób izolowania c zynnika krzepniecia VIII PL PL PL PL PL PL PL PL |
FI922105A FI103510B1 (fi) | 1989-11-09 | 1992-05-08 | Menetelmä tekijän VIII eristämiseksi |
BG96316A BG61231B1 (en) | 1989-11-09 | 1992-05-08 | A method for isolating factor viii |
NO921839A NO180741C (no) | 1989-11-09 | 1992-05-08 | Fremgangsmåte for isolering av Faktor VIII |
HRP-2105/90A HRP930277A2 (en) | 1989-11-09 | 1993-03-08 | A method for isolating biologically active compounds |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK562189 | 1989-11-09 | ||
DK562189A DK162233C (da) | 1989-11-09 | 1989-11-09 | Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii |
Publications (4)
Publication Number | Publication Date |
---|---|
DK562189D0 DK562189D0 (da) | 1989-11-09 |
DK562189A DK562189A (da) | 1991-05-10 |
DK162233B DK162233B (da) | 1991-09-30 |
DK162233C true DK162233C (da) | 1992-03-16 |
Family
ID=8144000
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK562189A DK162233C (da) | 1989-11-09 | 1989-11-09 | Fremgangsmaade til isolering af faktor viii fra blodplasma og pharmaceutisk praeparat indeholdende den saaledes isolerede fator viii |
Country Status (26)
Country | Link |
---|---|
US (1) | US5245014A (fr) |
EP (1) | EP0524172B1 (fr) |
JP (1) | JP2509407B2 (fr) |
CN (1) | CN1044121C (fr) |
AT (1) | ATE118508T1 (fr) |
AU (1) | AU631471B2 (fr) |
BG (1) | BG61231B1 (fr) |
CA (1) | CA2073012C (fr) |
CZ (1) | CZ537190A3 (fr) |
DE (1) | DE69017050T2 (fr) |
DK (1) | DK162233C (fr) |
ES (1) | ES2068404T3 (fr) |
FI (1) | FI103510B1 (fr) |
HU (1) | HU214905B (fr) |
IE (1) | IE66836B1 (fr) |
IL (1) | IL96277A (fr) |
NO (1) | NO180741C (fr) |
NZ (1) | NZ236004A (fr) |
PL (1) | PL164894B1 (fr) |
PT (1) | PT95830B (fr) |
RU (1) | RU2055593C1 (fr) |
SK (1) | SK537190A3 (fr) |
UA (1) | UA29421C2 (fr) |
WO (1) | WO1991007438A1 (fr) |
YU (1) | YU47524B (fr) |
ZA (1) | ZA908599B (fr) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2042138T3 (es) * | 1989-05-24 | 1993-12-01 | Miles Inc. | Filtracion en gel del factor viii tratado termicamente. |
US5859204A (en) * | 1992-04-07 | 1999-01-12 | Emory University | Modified factor VIII |
US6180371B1 (en) | 1996-06-26 | 2001-01-30 | Emory University | Modified factor VIII |
US5888974A (en) * | 1992-04-07 | 1999-03-30 | Emory University | Hybrid human/animal factor VIII |
US5659017A (en) * | 1995-11-07 | 1997-08-19 | Alpha Therapeutic Corporation | Anion exchange process for the purification of Factor VIII |
US7560107B2 (en) | 1996-06-26 | 2009-07-14 | Emory University | Modified factor VIII |
US6458563B1 (en) | 1996-06-26 | 2002-10-01 | Emory University | Modified factor VIII |
US6531577B1 (en) * | 1997-12-15 | 2003-03-11 | Hemasure Denmark A/S | von Willebrand factor (vWF)-containing preparation, process for preparing vWF-containing preparations, and use of such preparations |
US6290527B1 (en) * | 1998-07-03 | 2001-09-18 | Nippon Telegraph And Telephone Corp. | Nippon telegraph and telephone corporation |
US6586573B1 (en) | 1999-02-22 | 2003-07-01 | Baxter International Inc. | Albumin-free Factor VIII formulations |
JP2002348300A (ja) * | 1999-04-12 | 2002-12-04 | Fujimori Kogyo Co Ltd | 血液凝固第viii因子および血液凝固第viii因子/フォン・ビルブラント因子複合体の精製方法 |
AUPR638801A0 (en) * | 2001-07-13 | 2001-08-09 | Life Therapeutics Limited | Factor viii separation |
ES2449044T3 (es) | 2004-05-03 | 2014-03-18 | Emory University | Procedimiento de administración de fVIII sin dominio B porcino |
CN101010333B (zh) * | 2004-08-27 | 2013-08-14 | 诺和诺德医疗保健公司 | 从生物材料中纯化凝血因子xⅲ多肽 |
US20060226086A1 (en) * | 2005-04-08 | 2006-10-12 | Robinson Thomas C | Centrifuge for blood processing systems |
AU2009313325B2 (en) * | 2008-11-07 | 2014-05-01 | Takeda Pharmaceutical Company Limited | Factor VIII formulations |
BR112012024550B1 (pt) * | 2010-03-30 | 2020-12-08 | Octapharma Ag | processo de produção de uma proteína dependente de vitamina k livre de príons em uma sequência de purificação que emprega cromatografia |
RU2445974C2 (ru) * | 2010-04-26 | 2012-03-27 | Учреждение Российской академии медицинских наук Гематологический научный центр ГНЦ РАМН | Способ получения концентрата фактора viii из плазмы крови человека |
KR101948337B1 (ko) | 2010-11-05 | 2019-02-14 | 박스알타 인코퍼레이티드 | 증가된 특이 활성도를 갖는 항혈우병 인자 viii의 신규 변이체 |
CA2821711C (fr) | 2010-12-15 | 2017-10-10 | Baxter International Inc. | Recuperation d'eluat par utilisation d'un gradient de conductivite |
CN103506080A (zh) * | 2012-06-19 | 2014-01-15 | 汪志友 | 一种用于分离纯化凝血因子viii的介质及其制备方法 |
CA2886326C (fr) * | 2012-09-28 | 2021-11-02 | Chugai Seiyaku Kabushiki Kaisha | Procede d'evaluation de reaction de coagulation du sang |
US9663553B2 (en) | 2014-01-29 | 2017-05-30 | Hemarus Therapeutics Limited | Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4495175A (en) * | 1982-08-05 | 1985-01-22 | University Of Rochester | Preparation of highly purified human antihemophilic factor |
US4543210A (en) * | 1984-10-04 | 1985-09-24 | Miles Laboratories, Inc. | Process for producing a high purity antihemophilic factor concentrate |
DK525384D0 (da) * | 1984-11-05 | 1984-11-05 | Nordisk Insulinlab | Praeparat paa basis af faktor viii til behandling af haemofili a inhibitorpatienter samt fremgangsmaade til fremstilling af et saadan praeparat |
US4847362A (en) * | 1985-02-01 | 1989-07-11 | New York University | Method for purifying antihemophilic factor |
US4675385A (en) * | 1985-03-27 | 1987-06-23 | Alpha Therapeutic Corporation | Isolation of human plasma procoagulant protein factor VIII from biological factors |
US4758657A (en) * | 1985-07-11 | 1988-07-19 | Armour Pharmaceutical Company | Method of purifying Factor VIII:C |
AT391808B (de) * | 1986-11-03 | 1990-12-10 | Immuno Ag | Verfahren zur herstellung einer faktor viii (ahf)-haeltigen fraktion |
ATE112287T1 (de) * | 1987-12-21 | 1994-10-15 | Miles Inc | Faktor viii- gelfiltration. |
WO1989009784A1 (fr) * | 1988-04-08 | 1989-10-19 | Commonwealth Serum Laboratories Commission | Production de concentre de facteur viii thermostable |
ES2042138T3 (es) * | 1989-05-24 | 1993-12-01 | Miles Inc. | Filtracion en gel del factor viii tratado termicamente. |
-
1989
- 1989-11-09 DK DK562189A patent/DK162233C/da not_active IP Right Cessation
-
1990
- 1990-10-26 ZA ZA908599A patent/ZA908599B/xx unknown
- 1990-11-01 CZ CS905371A patent/CZ537190A3/cs unknown
- 1990-11-01 SK SK5371-90A patent/SK537190A3/sk unknown
- 1990-11-05 HU HU9201551A patent/HU214905B/hu unknown
- 1990-11-05 AT AT90917201T patent/ATE118508T1/de not_active IP Right Cessation
- 1990-11-05 UA UA94020494A patent/UA29421C2/uk unknown
- 1990-11-05 DE DE69017050T patent/DE69017050T2/de not_active Expired - Fee Related
- 1990-11-05 AU AU67470/90A patent/AU631471B2/en not_active Ceased
- 1990-11-05 CA CA002073012A patent/CA2073012C/fr not_active Expired - Lifetime
- 1990-11-05 JP JP3500067A patent/JP2509407B2/ja not_active Expired - Lifetime
- 1990-11-05 EP EP90917201A patent/EP0524172B1/fr not_active Expired - Lifetime
- 1990-11-05 WO PCT/DK1990/000279 patent/WO1991007438A1/fr active IP Right Grant
- 1990-11-05 RU SU905052211A patent/RU2055593C1/ru active
- 1990-11-05 ES ES90917201T patent/ES2068404T3/es not_active Expired - Lifetime
- 1990-11-07 US US07/610,480 patent/US5245014A/en not_active Expired - Lifetime
- 1990-11-07 NZ NZ236004A patent/NZ236004A/xx unknown
- 1990-11-07 YU YU210590A patent/YU47524B/sh unknown
- 1990-11-08 IE IE402290A patent/IE66836B1/en not_active IP Right Cessation
- 1990-11-08 PT PT95830A patent/PT95830B/pt not_active IP Right Cessation
- 1990-11-08 IL IL9627790A patent/IL96277A/en not_active IP Right Cessation
- 1990-11-09 PL PL90287703A patent/PL164894B1/pl unknown
- 1990-11-09 CN CN90109030A patent/CN1044121C/zh not_active Expired - Lifetime
-
1992
- 1992-05-08 BG BG96316A patent/BG61231B1/bg unknown
- 1992-05-08 FI FI922105A patent/FI103510B1/fi active
- 1992-05-08 NO NO921839A patent/NO180741C/no not_active IP Right Cessation
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