ATE85345T1 - Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. - Google Patents
Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung.Info
- Publication number
- ATE85345T1 ATE85345T1 AT88901838T AT88901838T ATE85345T1 AT E85345 T1 ATE85345 T1 AT E85345T1 AT 88901838 T AT88901838 T AT 88901838T AT 88901838 T AT88901838 T AT 88901838T AT E85345 T1 ATE85345 T1 AT E85345T1
- Authority
- AT
- Austria
- Prior art keywords
- fragment
- anf
- cdd
- arg
- ser
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 102400001279 Urodilatin Human genes 0.000 abstract 4
- IUCCYQIEZNQWRS-DWWHXVEHSA-N ularitide Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)N1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(O)=O)=O)[C@@H](C)CC)C1=CC=CC=C1 IUCCYQIEZNQWRS-DWWHXVEHSA-N 0.000 abstract 4
- 108010033276 Peptide Fragments Proteins 0.000 abstract 3
- 102000007079 Peptide Fragments Human genes 0.000 abstract 3
- 150000001413 amino acids Chemical group 0.000 abstract 3
- 108010001957 Ularitide Proteins 0.000 abstract 2
- 101800001849 Urodilatin Proteins 0.000 abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- 210000003734 kidney Anatomy 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Reproductive Health (AREA)
- Zoology (AREA)
- Ophthalmology & Optometry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873706731 DE3706731A1 (de) | 1987-03-02 | 1987-03-02 | Neues cardiodilatinfragment und verfahren zur gewinnung von cardiodilatinfragmenten |
| DE19873717329 DE3717329A1 (de) | 1987-05-22 | 1987-05-22 | Neues cardiodilatinfragment, verfahren zu seiner gewinnung und seine verwendung |
| DE3741641 | 1987-12-09 | ||
| PCT/EP1988/000144 WO1988006596A1 (en) | 1987-03-02 | 1988-02-27 | New cardiodilatin fragment, process for preparing same and use thereof |
| EP88901838A EP0349545B1 (de) | 1987-03-02 | 1988-02-27 | Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE85345T1 true ATE85345T1 (de) | 1993-02-15 |
Family
ID=27195544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88901838T ATE85345T1 (de) | 1987-03-02 | 1988-02-27 | Neues cadiodilatin-fragment, prozess zu dessen herstellung und dessen anwendung. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0349545B1 (de) |
| JP (1) | JP2819467B2 (de) |
| AT (1) | ATE85345T1 (de) |
| AU (1) | AU614738B2 (de) |
| DE (1) | DE3878231T2 (de) |
| DK (1) | DK174112B1 (de) |
| WO (1) | WO1988006596A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262521A (en) * | 1991-06-07 | 1993-11-16 | Sri International | Isolated atrial peptide-degrading enzyme and novel compounds useful as inhibitors thereof |
| DE4216133A1 (de) * | 1992-05-15 | 1993-11-18 | Bissendorf Peptide Gmbh | Anwendung von Urodilatin bei Lungen- und Bronchialerkrankungen |
| US5846932A (en) * | 1993-11-12 | 1998-12-08 | Genentech, Inc. | Receptor specific atrial natriuretic peptides |
| US5665704A (en) * | 1993-11-12 | 1997-09-09 | Genentech, Inc. | Receptor specific atrial natriuretic peptides |
| US6525022B1 (en) | 1993-11-12 | 2003-02-25 | Genentech, Inc. | Receptor specific atrial natriuretic peptides |
| JPH10500969A (ja) * | 1994-06-02 | 1998-01-27 | ベーリンガー マンハイム ゲゼルシャフト ミット ベシュレンクテル ハフツング | カルジオジラチンフラグメントの調製方法、高度に精製されたカルジオジラチンフラグメント及びそれらの調製のための中間生成物類 |
| DE19535445A1 (de) * | 1995-09-23 | 1997-03-27 | Boehringer Mannheim Gmbh | Verfahren zur Herstellung von natriuretischen Peptiden über Streptavidin-Fusionsproteine |
| US6136564A (en) * | 1995-11-16 | 2000-10-24 | Roche Diagnostics Gmbh | Process for the production of peptides by way of streptavidin fusion proteins |
| DE19951471A1 (de) * | 1999-10-26 | 2001-05-03 | Forssmann Wolf Georg | Verwendung von Urodilatin zur Behandlung chronischer Niereninsuffizienz mit Nierenrestfunktionen |
| DE10116552A1 (de) | 2001-04-03 | 2002-10-10 | Abc Armbruster Biochemicals | Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe |
| DK1865976T3 (da) | 2005-04-07 | 2012-07-23 | Cardiopep Pharma Gmbh | Anvendelse af natriuretiske peptider til behandling af hjertesvigt |
| US8580746B2 (en) | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
| WO2007115175A2 (en) | 2006-03-30 | 2007-10-11 | Palatin Technologies, Inc. | Cyclic natriuretic peptide constructs |
| CA2647146A1 (en) | 2006-03-30 | 2007-10-11 | Palatin Technologies, Inc. | Linear natriuretic peptide constructs |
| EP2185183B1 (de) * | 2007-09-11 | 2016-03-16 | Cardiopep Pharma GmbH | Verwendung von natriuretischen peptiden zur behandlung von angioödemen |
| EP2631247A1 (de) | 2012-02-22 | 2013-08-28 | Immundiagnostik AG | Mittel und Verfahren zum Messen des Parathyroid-Hormons bei unter oxidativem Stress leidenden Patienten |
| ES2689193T3 (es) | 2013-03-08 | 2018-11-08 | Immundiagnostik Ag | La hormona paratiroidea biológica activa no oxidada determina mortalidad en pacientes en hemodiálisis |
| WO2019141791A1 (en) | 2018-01-17 | 2019-07-25 | Immundiagnostik Ag | Biomarker predicting coronary artery disease |
| FR3099056B1 (fr) * | 2019-07-26 | 2022-08-12 | Univ Rouen Normandie | Utilisation de l’ANP pour détruire les biofilms bactériens |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1985004870A1 (en) * | 1984-04-19 | 1985-11-07 | Biotechnology Research Partners, Ltd. | Novel atrial natriuretic/vasodilator polypeptides |
| DE3443257A1 (de) * | 1984-11-28 | 1986-05-28 | Bissendorf Peptide GmbH, 3002 Wedemark | Mittel enthaltend vollsynthetisches alpha-humanes atriales natriuretisches peptid (alpha-hanap) |
-
1988
- 1988-02-27 AT AT88901838T patent/ATE85345T1/de not_active IP Right Cessation
- 1988-02-27 JP JP63502001A patent/JP2819467B2/ja not_active Expired - Lifetime
- 1988-02-27 DE DE8888901838T patent/DE3878231T2/de not_active Expired - Lifetime
- 1988-02-27 WO PCT/EP1988/000144 patent/WO1988006596A1/en not_active Ceased
- 1988-02-27 AU AU13481/88A patent/AU614738B2/en not_active Expired
- 1988-02-27 EP EP88901838A patent/EP0349545B1/de not_active Expired - Lifetime
- 1988-11-02 DK DK198806108A patent/DK174112B1/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1988006596A1 (en) | 1988-09-07 |
| DK174112B1 (da) | 2002-06-24 |
| AU1348188A (en) | 1988-09-26 |
| EP0349545B1 (de) | 1993-02-03 |
| AU614738B2 (en) | 1991-09-12 |
| JP2819467B2 (ja) | 1998-10-30 |
| DE3878231T2 (de) | 1993-05-27 |
| JPH02502636A (ja) | 1990-08-23 |
| DK610888A (da) | 1988-11-02 |
| DK610888D0 (da) | 1988-11-02 |
| DE3878231D1 (de) | 1993-03-18 |
| EP0349545A1 (de) | 1990-01-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |